A novel hyaluronan-based biomaterial (Hyaff-11) as a scaffold for endothelial cells in tissue engineered vascular grafts.

abstract：:The functionalization of polytetrafluoroethylene (PTFE) for human thrombomodulin (hTM) binding has been achieved by CO2 plasma activation and subsequent vapour phase graft polymerization of acrylic acid (AA). The PTFE surfaces after CO2 plasma treatment, AA grafting and hTM immobilization were characterized by attenua...

journal_title：Biomaterials

authors： Vasilets VN,Hermel G,König U,Werner C,Müller M,Simon F,Grundke K,Ikada Y,Jacobasch HJ

更新日期：1997-09-01 00:00:00

abstract：:Cyclic RGD peptide-decorated polymeric micellar-like nanoparticles (MNP) based on PEGylated poly (trimethylene carbonate) (PEG-PTMC) were prepared for active targeting to integrin-rich cancer cells. An amphiphilic diblock copolymer, α-carboxyl poly (ethylene glycol)-poly (trimethylene carbonate) (HOOC-PEG-PTMC), was s...

journal_title：Biomaterials

authors： Jiang X,Sha X,Xin H,Chen L,Gao X,Wang X,Law K,Gu J,Chen Y,Jiang Y,Ren X,Ren Q,Fang X

更新日期：2011-12-01 00:00:00

abstract：:Previously we have formulated a new cationic emulsion, composed of 3beta [N-(N',N'-dimethylaminoethane) carbamoyl] cholesterol and dioleoylphosphatidyl ethanolamine, castor oil and Tween 80, and it efficiently delivered plasmid DNA into various cancer cells with low toxicity. Chitosan is a natural cationic polysacchar...

journal_title：Biomaterials

authors： Lee MK,Chun SK,Choi WJ,Kim JK,Choi SH,Kim A,Oungbho K,Park JS,Ahn WS,Kim CK

更新日期：2005-05-01 00:00:00

abstract：:Osteoclasts resorb bone at surfaces, leaving behind pits and trails where both mineral and organic phases of bone have been dissolved. Rough surface structures are deliberately imparted to synthetic implants, in order to improve osseointegration. The aim of this study is to characterize osteoclastic resorption pits on...

journal_title：Biomaterials

authors： Hefti T,Frischherz M,Spencer ND,Hall H,Schlottig F

更新日期：2010-10-01 00:00:00

abstract：:Tissue-engineered muscle is a viable option for tissue repair, though presently technologies are not developed enough to produce tissue in vitro identical to that in vivo. One important step in generating accurate engineered muscle is to mimic natural muscle architecture. Skeletal muscle is composed of fibrils whose o...

journal_title：Biomaterials

authors： Lam MT,Sim S,Zhu X,Takayama S

更新日期：2006-08-01 00:00:00

abstract：:The effective role of exosome delivering neurogenic microRNA (miRNA) enables to induce efficient differentiation process during neurogenesis. The microfludic system capable of visualizing the exosomal behavior such as secretion, migration, and uptake of individual exosomes can be used as a robust technique to understa...

journal_title：Biomaterials

authors： Oh HJ,Shin Y,Chung S,Hwang DW,Lee DS

更新日期：2017-01-01 00:00:00

abstract：:Lung fibrosis is a poor prognostic factor for pulmonary adenocarcinoma, and the effect of a rigid microenvironment on cancer behavior is unclear. We cultured A549 cells on matrices of 0.2, 2, and 25 kPa to mimic the rigidities of normal lung parenchyma, progressive fibrotic change, and lung fibrosis, respectively. Lun...

journal_title：Biomaterials

authors： Chang CC,Hsieh TL,Tiong TY,Hsiao CH,Ji AT,Hsu WT,Lee OK,Ho JH

更新日期：2015-08-01 00:00:00

abstract：:The purpose of this study was to quantify and compare the amount of water absorbed by six commercially available resin-modified glass ionomer cements and to investigate the possible influence of time and resin content on water sorption. The materials evaluated included Variglass used as a restoration, base and liner; ...

journal_title：Biomaterials

authors： Yap AU

更新日期：1996-10-01 00:00:00

abstract：:Metronomic chemotherapy, which is defined as a low-dose and frequent administration of cytotoxic drugs without drug-free breaks, has been recently emerged as an alternative to traditional MTD therapy and has shown therapeutic benefit in breast cancer patients in numbers of clinical studies. Unlike MTD, metronomic chem...

journal_title：Biomaterials

authors： Chung SW,Kim GC,Kweon S,Lee H,Choi JU,Mahmud F,Chang HW,Kim JW,Son WC,Kim SY,Byun Y

更新日期：2018-11-01 00:00:00

abstract：:Elemental metal nanoparticles like cadmium and silver are known to cause oxidative stress and are also highly toxic. Yet for gold nanoparticles (AuNPs), it is not well established whether these particles are biologically toxic. Here we show that AuNPs, which were taken up by MRC-5 human lung fibroblasts in vitro, indu...

journal_title：Biomaterials

authors： Li JJ,Hartono D,Ong CN,Bay BH,Yung LY

更新日期：2010-08-01 00:00:00

abstract：:Measurements were made of the extremes in temperature which occur at different sites in the oral cavity during fluid intake. The results indicate that temperatures noted at the tooth surface, within the mouth, during fluid intake were less than the temperatures of the fluid imbibed. Variations in temperature were note...

journal_title：Biomaterials

authors： Longman CM,Pearson GJ

更新日期：1987-09-01 00:00:00

abstract：:Nano- to micro-structured biodegradable poly(L-lactide-co-epsilon-caprolactone) (PLCL) fabrics were prepared by electrospinning. Electrospun microfiber fabrics with different compositions of PLCL (mol% in feed; 70/30, 50/50, and 30/70), poly(L-lactide) (PLL) and poly(epsilon-caprolactone) (PCL) were obtained using met...

journal_title：Biomaterials

authors： Kwon IK,Kidoaki S,Matsuda T

更新日期：2005-06-01 00:00:00

abstract：:The adsorption of chondroitin-4-sulphate (C4S) and heparin onto titanium has been studied in the absence and presence of bovine serum albumin (BSA). Isotherm data (0.02 M calcium acetate, pH 6.8) have shown that BSA in solution and BSA-coated titanium result in decreased adsorption for both C4S and heparin. For the BS...

journal_title：Biomaterials

authors： Hughes Wassell DT,Embery G

更新日期：1997-08-01 00:00:00

abstract：:Autologous melanocyte transplantation for vitiligo treatment by use of melanocyte suspension has drawbacks including cell damage in cell preparation and transportation, difficult manipulation and low engraftment rate in acral vitiligious lesions. We have proposed the concept of cellular patch as an alternative solutio...

journal_title：Biomaterials

authors： Lin SJ,Jee SH,Hsiao WC,Yu HS,Tsai TF,Chen JS,Hsu CJ,Young TH

更新日期：2006-03-01 00:00:00

abstract：:The reaction of calcium ions and organic phosphate ester monomer at varying pHs was examined. Above pH 10, poorly crystallized hydroxyapatite was formed, which had lower crystallinity than that synthesized with inorganic phosphate as a source of P under the same conditions. On the other hand, the results of X-ray diff...

journal_title：Biomaterials

authors： Okazaki M,Hattori M

更新日期：1989-03-01 00:00:00

abstract：:The aim of this study was to follow the in vivo biodegradation as well as to appreciate the brain tissue response to poly(methylidene malonate 2.1.2) (PMM 2.1.2)-based microspheres implanted into the rat brain. Ninety-three adult Sprague-Dawley female rats were engaged in the study in which 54 underwent stereotactic i...

journal_title：Biomaterials

authors： Fournier E,Passirani C,Colin N,Sagodira S,Menei P,Benoit JP,Montero-Menei CN

更新日期：2006-10-01 00:00:00

abstract：:A multifunctional organic-inorganic hybrid nanocapsule based on Bi2S3-embedded poly (lactic-co-glycolic acid) (PLGA) nanocapsule has been elaborately designed to combine the merits of both polymeric shell structure and Bi2S3 nanoparticles. Hydrophobic Bi2S3 nanoparticles were successfully introduced into the PLGA nano...

journal_title：Biomaterials

authors： Yao MH,Ma M,Chen Y,Jia XQ,Xu G,Xu HX,Chen HR,Wu R

更新日期：2014-09-01 00:00:00

abstract：:The non-specific interaction between nanoparticles (NPs) and plasma proteins occurs immediately after NPs enter the blood, resulting in the formation of the protein corona that thereafter replaces the original NPs and becomes what the organs and cells really see. Consequently, the in vivo fate of NPs and the biologica...

journal_title：Biomaterials

authors： Peng Q,Zhang S,Yang Q,Zhang T,Wei XQ,Jiang L,Zhang CL,Chen QM,Zhang ZR,Lin YF

更新日期：2013-11-01 00:00:00

abstract：:Multiblock, high molecular weight, linear, backbone degradable HPMA copolymer-prostaglandin E1 (PGE1) conjugate has been synthesized by RAFT polymerization mediated by a new bifunctional chain transfer agent (CTA), which contains an enzymatically degradable oligopeptide sequence flanked by two dithiobenzoate groups, f...

journal_title：Biomaterials

authors： Pan H,Sima M,Miller SC,Kopečková P,Yang J,Kopeček J

更新日期：2013-09-01 00:00:00

abstract：:Implant stability is not only a function of strength but also depends on the fixation established with surrounding tissues [Robertson DM, Pierre L, Chahal R. Preliminary observations of bone ingrowth into porous materials. J Biomed Mater Res 1976;10:335-44]. In the past, such stability was primarily achieved using scr...

journal_title：Biomaterials

authors： Ryan G,Pandit A,Apatsidis DP

更新日期：2006-05-01 00:00:00

abstract：:In arterial replacement there is a clear clinical need for a functional substitute possessing appropriate haemocompatible properties to be implanted as small diameter artery. Endothelial cell seeding constitutes an appreciated method to improve blood compatibility on the condition that cells firmly adhere to the suppo...

journal_title：Biomaterials

authors： Rémy M,Durand M,Menu P,Voegel JC,Ponsot JF,Bérard X,Harmand MF,Bordenave L

更新日期：2013-12-01 00:00:00

abstract：:Targeted theranostic nano-system integrating functions of both diagnosis and therapy shows great potential for improving diagnosis and therapeutic efficacy. Herein, multifunctional nanoparticle based on activatable hyaluronic acid (HA) conjugating two near-infrared (NIR) dyes of Cy5.5 and IR825 was successfully design...

journal_title：Biomaterials

authors： Liang X,Fang L,Li X,Zhang X,Wang F

更新日期：2017-07-01 00:00:00

abstract：:A nanocarrier delivery system that can simultaneously deliver a chemotherapeutic drug and siRNA to the tumor is emerging as a promising treatment strategy for cancer treatment. In this study, a multifunctional PHD/PPF/siRNA complexes was developed by one-step assembly of prefunctionalized polymers: PEI-HZ-DOX (PHD) an...

journal_title：Biomaterials

authors： Dong DW,Xiang B,Gao W,Yang ZZ,Li JQ,Qi XR

更新日期：2013-07-01 00:00:00

abstract：:Immune checkpoint blocking (ICB) antibodies have shown great success in the clinic, but their low response rate in patients with immunosuppressive cold tumors remains a huge challenge. Inspired by the capability of immunogenic cell death (ICD) to convert tumors from cold to hot, we developed a corn-like Au/Ag nanorod ...

journal_title：Biomaterials

authors： Jin L,Shen S,Huang Y,Li D,Yang X

更新日期：2021-01-01 00:00:00

abstract：:A range of poly(alkyl methacrylate)s in the range C5 to C13 with varying degrees of crosslinking, have been studied with respect to stress-strain behaviour. Where the extensions to break were sufficiently high, stress-strain properties conformed well to the statistical theory of rubber elasticity, the Mooney/Rivlin C2...

journal_title：Biomaterials

authors： Davy KW,Braden M

更新日期：1987-09-01 00:00:00

abstract：:We report here the study of the biocompatibility of a bone graft material, the Pyrost, using a previously established in vitro model of human osteoblasts. The effect of this material on cell proliferation was evaluated by the MTS assay. Results indicated the absolute absence of cytotoxic or cytostatic effect of Pyrost...

journal_title：Biomaterials

authors： Josset Y,Oum'hamed Z,Zarrinpour A,Lorenzato M,Adnet JJ,Laurent-Maquin D

更新日期：1998-10-01 00:00:00

abstract：:Alginate/aminopropyl-silicate/alginate (Alg/AS/Alg) membrane was prepared on Ca-alginate gel beads by a sol-gel process. The membrane has identical to Si-O-Si identical to bonds as well as electrostatic bonds between amino groups of AS and carboxyl groups of alginate. Permeability and stability were investigated for t...

journal_title：Biomaterials

authors： Sakai S,Ono T,Ijima H,Kawakami K

更新日期：2002-11-01 00:00:00

abstract：:The present study provides in vivo trials of silicone rubber chambers filled with different concentrations of bilobalide (0, 50, 100, 200, 400 microM) to bridge a 15 mm sciatic nerve defect in rats. Collagen was also filled in the chambers to prevent the bilobalide from leakage. Histological and electrophysiological t...

journal_title：Biomaterials

authors： Chen YS,Liu CJ,Cheng CY,Yao CH

更新日期：2004-02-01 00:00:00

abstract：:The microstructure of TiTa30 alloys diffusion bonded to a 99.7 wt% Al2O3 ceramic was subdivided into a reaction double layer containing the intermetallic phases TiAl and Ti3Al and the (alpha + beta) Ti microstructure. Excellent fracture toughness data of the TiTa30/Al2O3 joints of about 37 J/m2 were obtained after wel...

journal_title：Biomaterials

authors： Gibbesch B,Elssner G,Petzow G

更新日期：1992-01-01 00:00:00

abstract：:Fibrillar type I collagen is nontoxic, biocompatible, and possesses considerable strength and stability. In a study of scaffolds for use in laminated tissue substitutes, we examined the properties of membranes made from air-dried hydrogels of collagen fibrils that were polymerized from native, monomeric collagen. Plan...

journal_title：Biomaterials

authors： Vernon RB,Gooden MD,Lara SL,Wight TN

更新日期：2005-04-01 00:00:00