Microwave CO2 plasma-initiated vapour phase graft polymerization of acrylic acid onto polytetrafluoroethylene for immobilization of human thrombomodulin.

abstract：:In this work, the in vitro interaction of cerebellar granule neurons prepared from 7-day-old Wistar rats and poly ethylene-co-vinyl alcohol (EVAL) membranes was investigated. Cells were cultured in smooth and particulate EVAL membranes for up to 7 days. Particulate membranes were prepared by using 1-octanol to precipi...

journal_title：Biomaterials

authors： Young TH,Lin CW,Cheng LP,Hsieh CC

更新日期：2001-07-01 00:00:00

abstract：:The Debye Function Analysis of diffraction patterns from nanosized mineral crystals showing different average degrees of maturity was carried out on engineered bone samples. The analysis relied on a bivariate family of atomistic hydroxyapatite nanocrystal models and provided information about crystal structure, size a...

journal_title：Biomaterials

authors： Guagliardi A,Cedola A,Giannini C,Ladisa M,Cervellino A,Sorrentino A,Lagomarsino S,Cancedda R,Mastrogiacomo M

更新日期：2010-11-01 00:00:00

abstract：:Over the last few decades, colloidal drug delivery systems (CDDS) such as nano-structures have been developed in order to improve the efficiency and the specificity of drug action. Their small size permits them to be injected intravenously in order to reach target tissues. However, it is known that they can be rapidly...

journal_title：Biomaterials

authors： Vonarbourg A,Passirani C,Saulnier P,Benoit JP

更新日期：2006-08-01 00:00:00

abstract：:Micro/nanotopographical modification of biomaterials constitutes a promising approach to direct stem cell osteogenic differentiation to promote osseointegration. In this work, titania nanotubes (NTs) 25 and 80 nm in size with the acid-etched Ti topography (AcidTi) and hierarchical hybrid micropitted/nanotubular topogr...

journal_title：Biomaterials

authors： Zhao L,Liu L,Wu Z,Zhang Y,Chu PK

更新日期：2012-03-01 00:00:00

abstract：:Personalized oncology significantly relies on the development of cancer theranostic agents to integrate cancer therapeutics and diagnostics. Current most common strategy for development of such multifunctional agents requires multistep chemical conjugation with cancer targeted ligands, contrast agents and therapeutic ...

journal_title：Biomaterials

authors： Luo S,Tan X,Qi Q,Guo Q,Ran X,Zhang L,Zhang E,Liang Y,Weng L,Zheng H,Cheng T,Su Y,Shi C

更新日期：2013-03-01 00:00:00

abstract：:Permanent male sterilization has been recognized as useful tools for the development of neuter experimental animals and fattening livestock, as well as efficient control of pet overpopulation. Traditional routes such as surgical ways, chemical injections, and anti-fertility vaccines have addressed these crucial proble...

journal_title：Biomaterials

authors： Liu Z,Liu X,Ran X,Ju E,Ren J,Qu X

更新日期：2015-11-01 00:00:00

abstract：:This highly absorbent, biodegradable dressing derived from seaweed can be successfully applied to cleanse a wide variety of secreting lesions. The high absorption of exudate is achieved via strong hydrophilic gel formation and this serves to control wound secretion levels and to minimize bacterial contamination. Algin...

journal_title：Biomaterials

authors： Gilchrist T,Martin AM

更新日期：1983-10-01 00:00:00

abstract：:The interactions between alginate and polycations have been studied by using different labelling techniques. Binding of poly-L-lysine (PLL) to alginate in the gel state is mainly governed by the amount of dissociable negative charges on the bead surface. PLL was found to bind more rapidly to gel beads made from algina...

journal_title：Biomaterials

authors： Thu B,Bruheim P,Espevik T,Smidsrød O,Soon-Shiong P,Skjåk-Braek G

更新日期：1996-05-01 00:00:00

abstract：:It is estimated that 4 to 5 million people are currently co-infected with Human Immunodeficiency Virus (HIV) and Hepatitis C Virus (HCV). HIV/HCV co-infection is associated with unique health risks including increased hepatotoxicity of antiretrovirals, accelerated progression of HCV and liver diseases. The standard in...

journal_title：Biomaterials

authors： Zhang J,Mulvenon A,Makarov E,Wagoner J,Knibbe J,Kim JO,Osna N,Bronich TK,Poluektova LY

更新日期：2013-05-01 00:00:00

abstract：:The biological activity of osteoblasts on the newly developed bioactive poly(methyl methacrylate) (PMMA)/silica hybrid containing calcium salt was investigated. The attachment, proliferation, and differentiation of primary cultured mouse calvarial osteoblasts were evaluated by hexosaminase, MTT, and alkaline phosphata...

journal_title：Biomaterials

authors： Rhee SH,Hwang MH,Si HJ,Choi JY

更新日期：2003-03-01 00:00:00

abstract：:Acetaminophen (APAP) is the most widely used analgesic and its overdose, intentional or unintentional, is known to cause massive oxidative stress and liver tissue damages characterized by hepatocellular apoptosis and hemorrhagic necrosis, leading to acute liver failure (ALF). There has been great interest in the use o...

journal_title：Biomaterials

authors： Ko E,Jeong D,Kim J,Park S,Khang G,Lee D

更新日期：2014-04-01 00:00:00

abstract：:Cell delivery in cell therapy is typically challenged by the low cell survival rate and immunological rejection during cells injection and circulation. Encapsulation of cells with semipermeable hydrogels or membranes can improve cell viability by resisting high shear force and inhibit immune response with the physical...

journal_title：Biomaterials

authors： Yang J,Yang Y,Kawazoe N,Chen G

更新日期：2019-03-01 00:00:00

abstract：:Recently, chitosan-gelatin scaffolds have gained much attention in various tissue engineering applications. However, the underlying cell-matrix interactions remain unclear in addition to the scaffold degradation and mechanical characteristics. In this study, we evaluated (i) the degradation kinetics of chitosan and ch...

journal_title：Biomaterials

authors： Huang Y,Onyeri S,Siewe M,Moshfeghian A,Madihally SV

更新日期：2005-12-01 00:00:00

abstract：:Local signals from tissue-specific extracellular matrix (ECM) microenvironments, including matrix adhesive ligand, mechanical elasticity and micro-scale geometry, are known to instruct a variety of stem cell differentiation processes. Likewise, these signals converge to provide multifaceted, mechanochemical cues for h...

journal_title：Biomaterials

authors： Floren M,Tan W

更新日期：2015-08-01 00:00:00

abstract：:Bioactive glass is used as both a bone filler and as a coating on implants, and has been advocated as a potential osteogenic scaffold for tissue engineering. Rat-derived mesenchymal stem cells (MSCs) show elevated levels of alkaline phosphatase activity when grown on 45S5 bioactive glass as compared to standard tissue...

journal_title：Biomaterials

authors： Reilly GC,Radin S,Chen AT,Ducheyne P

更新日期：2007-10-01 00:00:00

abstract：:The advancement in gene therapy relies upon the discovery of safe and efficient delivery agents and methods. In this study, we report the design and synthesis of a cationic bolaamphiphile as a non-viral gene delivery agent. The bolaamphiphile is composed of 1,12-diaminododecane as the central hydrophobic unit linked t...

journal_title：Biomaterials

authors： Khan M,Ang CY,Wiradharma N,Yong LK,Liu S,Liu L,Gao S,Yang YY

更新日期：2012-06-01 00:00:00

abstract：:Recent studies have shown that extracellular matrix (ECM) substitutes can have a dramatic impact on cell growth, differentiation and function. However, these ECMs are often applied generically and have yet to be developed for specific cell types. In this study, we developed tissue-specific ECM-based coating substrates...

journal_title：Biomaterials

authors： Zhang Y,He Y,Bharadwaj S,Hammam N,Carnagey K,Myers R,Atala A,Van Dyke M

更新日期：2009-08-01 00:00:00

abstract：:Hydrogels are a promising type of biomaterial for articular cartilage constructs since they have been shown to enable encapsulated chondrocytes to express their predominant phenotypic marker, type II collagen. Endogenously expressed signaling molecules, such as insulin-like growth factor-1 (IGF-1), are also known to f...

journal_title：Biomaterials

authors： Yoon DM,Hawkins EC,Francke-Carroll S,Fisher JP

更新日期：2007-01-01 00:00:00

abstract：:Fibronectin (Fn) forms a fibrillar network that controls cell behavior in both physiological and diseased conditions including cancer. Indeed, breast cancer-associated stromal cells not only increase the quantity of deposited Fn but also modify its conformation. However, (i) the interplay between mechanical and confor...

journal_title：Biomaterials

authors： Wang K,Andresen Eguiluz RC,Wu F,Seo BR,Fischbach C,Gourdon D

更新日期：2015-06-01 00:00:00

abstract：:It is now well accepted that the initial rapid adsorption of blood proteins to biomaterial surfaces is important in the long-term performance of the implant. Cells that interact with the implant will be reacting to a layer (single or multiple) of adsorbed protein. The parameters of importance in a study of protein ads...

journal_title：Biomaterials

authors： Chittur KK

更新日期：1998-03-01 00:00:00

abstract：:Artemisinin (ART) is an iron-dependent anti-cancer drug. However, simultaneous delivery of hydrophobic ART and Fe(2+) ions into cancer cells remains a major challenge. Herein, we reported Fe3O4@C/Ag@mSiO2 (FCA@mSiO2) multifunctional nanocarriers which can load ART as high as 484 mg/g. Moreover, FCA@mSiO2 nanoparticles...

journal_title：Biomaterials

authors： Chen J,Guo Z,Wang HB,Zhou JJ,Zhang WJ,Chen QW

更新日期：2014-08-01 00:00:00

abstract：:The aim of our study was the evaluation of a cell-free cartilage implant that allows the recruitment of mesenchymal stem and progenitor cells by chemo-attractants and subsequent guidance of the progenitors to form cartilage repair tissue after microfracture. Chemotactic activity of human serum on human mesenchymal pro...

journal_title：Biomaterials

authors： Erggelet C,Neumann K,Endres M,Haberstroh K,Sittinger M,Kaps C

更新日期：2007-12-01 00:00:00

abstract：:Current synthetic vascular grafts possess a significant mechanical mismatch compared to the native vasculature and do not permit endothelialization; both of these deficiencies contribute to the relatively high rate of failure of many synthetic grafts. In this communication, we report the modification of polyurethane (...

journal_title：Biomaterials

authors： Chuang TW,Masters KS

更新日期：2009-10-01 00:00:00

abstract：:In spite of good prospects for bone morphogenetic proteins (BMP) applications, an ideal carrier system for BMPs has not yet been identified. The purpose of this study was to evaluate the osteogenic effect of a fibrin-fibronectin sealing system (FFSS) combined with beta-tricalcium phosphate (beta-TCP) as a carrier syst...

journal_title：Biomaterials

authors： Hong SJ,Kim CS,Han DK,Cho IH,Jung UW,Choi SH,Kim CK,Cho KS

更新日期：2006-07-01 00:00:00

abstract：:Biomimetic materials are often capable of subtly affecting tissue development, regeneration and carcinogenesis due to their high similarity to natural tissues. Despite the benefit of using such materials in tissue engineering, their prospective use in cancer therapy has been neglected, particularly the functions and m...

journal_title：Biomaterials

authors： Li X,Wang Y,Chen Y,Zhou P,Wei K,Wang H,Wang J,Fang H,Zhang S

更新日期：2020-10-01 00:00:00

abstract：:Tubular vessels for tissue engineering are typically fabricated using a molding, dipping, or electrospinning technique. While these techniques provide some control over inner and outer diameters of the tube, they lack the ability to align the polymers or fibers of interest throughout the tube. This is an important asp...

journal_title：Biomaterials

authors： Lovett ML,Cannizzaro CM,Vunjak-Novakovic G,Kaplan DL

更新日期：2008-12-01 00:00:00

abstract：:A major role of respiratory mucus is to trap inhaled particles, including pathogens and environmental particulates, to limit body exposure. Despite the tremendous health implications, how particle size and surface chemistry affect mobility in respiratory mucus from humans without lung disease is not known. We prepared...

journal_title：Biomaterials

authors： Schuster BS,Suk JS,Woodworth GF,Hanes J

更新日期：2013-04-01 00:00:00

abstract：:The goal of this study was to develop a polymeric carrier for delivery of anti-tumor drugs and sustained release of these agents in order to optimize anti-tumor activity while minimizing systemic effects. We used oligo(poly(ethylene glycol) fumarate) (OPF) hydrogels modified with small negatively charged molecules, so...

journal_title：Biomaterials

authors： Dadsetan M,Liu Z,Pumberger M,Giraldo CV,Ruesink T,Lu L,Yaszemski MJ

更新日期：2010-11-01 00:00:00

abstract：:Artificial extracellular matrix proteins, genetically engineered from elastin- and fibronectin-derived repeating units, were crosslinked with hexamethylene diisocyanate in dimethylsulfoxide. The resulting hydrogel films were transparent, uniform, and highly extensible. Their tensile moduli depended on crosslinker conc...

journal_title：Biomaterials

authors： Nowatzki PJ,Tirrell DA

更新日期：2004-03-01 00:00:00

abstract：:Highly fluorescent core-shell silica nanoparticles made by the modified Stöber process (C dots) are promising as tools for sensing and imaging subcellular agents and structures but will only be useful if they can be easily delivered to the cytoplasm of the subject cells. This work shows that C dots can be electrostati...

journal_title：Biomaterials

authors： Fuller JE,Zugates GT,Ferreira LS,Ow HS,Nguyen NN,Wiesner UB,Langer RS

更新日期：2008-04-01 00:00:00