Wound treatment with Sorbsan--an alginate fibre dressing.

abstract：:This work reports the development of new non-thrombogenic polymers based on the linear polymers of polyamidoamines (PAAs), having heparin binding ability, obtained by polyaddition of secondary amines to N,N'-methylene bis-acrylamide. PAAs could not be used directly in the making of blood-contacting materials due to th...

journal_title：Biomaterials

authors： Dey RK,Ray AR

更新日期：2003-08-01 00:00:00

abstract：:Non-invasive assay for the early stage diagnosis of methicillin resistant Staphylococcus aureus (MRSA) related pneumonia is of great clinical importance and still a great challenge. In this paper, we reported a novel kind of Au@Ag core-shell theranostic nanoparticles (NPs) conjugated with MRSA specific antibody on the...

journal_title：Biomaterials

authors： Huo D,Ding J,Cui YX,Xia LY,Li H,He J,Zhou ZY,Wang HW,Hu Y

更新日期：2014-08-01 00:00:00

abstract：:This animal experiment compared the regenerative processes within defined bony defects of the porcine skull after delivery of routinely utilized bone graft materials: anorganic bone matrix (ABM) and an identical ABM carrying the cell binding peptide P-15. Particulated autogenous bone was used as a control group. The c...

journal_title：Biomaterials

authors： Thorwarth M,Schultze-Mosgau S,Wehrhan F,Kessler P,Srour S,Wiltfang J,Andreas Schlegel K

更新日期：2005-10-01 00:00:00

abstract：:A comparative in vitro assessment of 4 types of tubing representative of the materials currently used in cardiopulmonary bypass (CPB) procedures was conducted under static conditions using liquid extracts of the materials or direct contact with fresh human blood or serum. The parameters monitored were biomarkers of co...

journal_title：Biomaterials

authors： Harmand MF,Briquet F

更新日期：1999-09-01 00:00:00

abstract：:The performance of implantable biomaterials derived from decellularized tissue, including encouraging results with skeletal muscle, suggests that the extracellular matrix (ECM) derived from native tissue has promising regenerative potential. Yet, the supply of biomaterials derived from donated tissue will always be li...

journal_title：Biomaterials

authors： Hurd SA,Bhatti NM,Walker AM,Kasukonis BM,Wolchok JC

更新日期：2015-05-01 00:00:00

abstract：:Checkpoint blocking antibodies that interfere in the PD-1/PD-L1 axis provide effective cancer immunotherapy for tumors that are immune inflamed or induced to become "hot". It has also been demonstrated that a small molecule inhibitor of the signaling hub kinase GSK3 can interfere in the PD-1/PD-L1 axis in T-cells by s...

journal_title：Biomaterials

authors： Allen SD,Liu X,Jiang J,Liao YP,Chang CH,Nel AE,Meng H

更新日期：2020-12-28 00:00:00

abstract：:In order to evaluate degradation kinetics and biocompatibility of a resorbable poly(D,L-lactic acid) (PDLLA) plug for total cemented hip prostheses, an experimental in vitro and in vivo study was carried out. Degradation rate studies were performed in Ringer solution and after in vivo plug implantation in the femoral ...

journal_title：Biomaterials

authors： Giardino R,Fini M,Aldini NN,Giavaresi G,Rocca M,Orienti L,de Lollis A,Fambri L

更新日期：1997-07-01 00:00:00

abstract：:Geliperm hydrogel provides optimal physiological conditions for wound healing. The material is composed of two interlaced networks, one of polyacrylamide and one of agar, and contains about 96% firmly bound water. It is supplied in smooth, elastic, transparent sheets which are impermeable to bacteria but permeable to ...

journal_title：Biomaterials

authors： Kickhöfen B,Wokalek H,Scheel D,Ruh H

更新日期：1986-01-01 00:00:00

abstract：:Myocardial infarction (MI) leads to the mass death of cardiomyocytes accompanying with the unfavorable alternation of microenvironment, a fibrosis scar deprived of electrical communications, and the lack of blood supply in the infarcted myocardium. The three factors are inextricably intertwined and thus result in a co...

journal_title：Biomaterials

authors： Wang W,Tan B,Chen J,Bao R,Zhang X,Liang S,Shang Y,Liang W,Cui Y,Fan G,Jia H,Liu W

更新日期：2018-04-01 00:00:00

abstract：:A amphiphilic block copolymer composed of conventional monomethoxy (polyethylene glycol)-poly (d,l-lactide-co-glycolide)-poly (l-lysine) (mPEG-PLGA-b-PLL) was synthesized. The chemical structure of this copolymer and its precursors was confirmed by Fourier Transform Infrared Spectroscopy (FTIR), (1)H Nuclear Magnetic ...

journal_title：Biomaterials

authors： Liu P,Yu H,Sun Y,Zhu M,Duan Y

更新日期：2012-06-01 00:00:00

abstract：:The present study provides in vivo trials of silicone rubber chambers filled with different concentrations of bilobalide (0, 50, 100, 200, 400 microM) to bridge a 15 mm sciatic nerve defect in rats. Collagen was also filled in the chambers to prevent the bilobalide from leakage. Histological and electrophysiological t...

journal_title：Biomaterials

authors： Chen YS,Liu CJ,Cheng CY,Yao CH

更新日期：2004-02-01 00:00:00

abstract：:We describe a near-infrared fluorescent heptamethine dye (IR-780 iodide) with unique properties for sentinel lymph node (SLN) mapping in both small and large animals. This dye has a significant photobrightening effect in serum and a long retention time in the lymphatic system which allows to acquire much higher signal...

journal_title：Biomaterials

authors： Zhang C,Wang S,Xiao J,Tan X,Zhu Y,Su Y,Cheng T,Shi C

更新日期：2010-03-01 00:00:00

abstract：:In order to clarify the role of a primer on the adhesion between dental precious metals and resin, surface-enhanced Raman scattering (SERS) technique has been applied to the structural analysis of the adhesive monomer, 6-(N-(4-vinylbenzyl)propylamino)-1,3,5-triazine-2, 4-dithione (VBATDT) adsorbed on colloidal Au surf...

journal_title：Biomaterials

authors： Suzuki M,Fujishima A,Miyazaki T,Hisamitsu H,Kojima K,Kadoma Y

更新日期：1999-05-01 00:00:00

abstract：:Restoration of tissue integrity and tissue function of wounded skin are both essential for wound repair and regeneration, while synergistic promotion of the two remains elusive. Since elevated reactive oxygen species (ROS) production in the injured site has been implicated in triggering a set of deleterious effects su...

journal_title：Biomaterials

authors： Wu H,Li F,Wang S,Lu J,Li J,Du Y,Sun X,Chen X,Gao J,Ling D

更新日期：2018-01-01 00:00:00

abstract：:The combined use of natural ECM components and synthetic materials offers an attractive alternative to fabricate hydrogel-based tissue engineering scaffolds to study cell-matrix interactions in three-dimensions (3D). A facile method was developed to modify gelatin with cysteine via a bifunctional PEG linker, thus intr...

journal_title：Biomaterials

authors： Fu Y,Xu K,Zheng X,Giacomin AJ,Mix AW,Kao WJ

更新日期：2012-01-01 00:00:00

abstract：:Realizing the potential of human pluripotent stem cell (hPSC)-based therapy requires the development of defined scalable culture systems with efficient expansion, differentiation and isolation protocols. We report an engineered 3D microfiber system that efficiently supports long-term hPSCs self-renewal under chemicall...

journal_title：Biomaterials

authors： Lu HF,Narayanan K,Lim SX,Gao S,Leong MF,Wan AC

更新日期：2012-03-01 00:00:00

abstract：:The degree of metal ion dissolution from Ti-6Al-4V alloy hip replacement stems subjected to various mechanical and chemical surface pretreatments was analysed in vitro. High-dissolution rates were observed for nitric acid passivated samples that had been mechanically surface treated to increase the implant surface are...

journal_title：Biomaterials

authors： Browne M,Gregson PJ

更新日期：2000-02-01 00:00:00

abstract：:Aberrant regulation of angiogenesis supply sufficient oxygen and nutrients to exacerbate tumor progression and metastasis. Taking this hallmark of cancer into account, reported here is a self-monitoring and triple-collaborative therapy system by auto-fluorescent polymer nanotheranostics which could be concurrently aga...

journal_title：Biomaterials

authors： Shao L,Li Q,Zhao C,Lu J,Li X,Chen L,Deng X,Ge G,Wu Y

更新日期：2019-02-01 00:00:00

abstract：:Polylactide (PLA) microspheres were coated with collagen for cell culture and injectable cell carriers. Utilizing a method of emulsion-solvent evaporation, PLA microspheres with diameter ranging from 180 to 280 microm were prepared, followed with aminolysis in hexanediamine/n-propanol solution to introduce free amino ...

journal_title：Biomaterials

authors： Hong Y,Gao C,Xie Y,Gong Y,Shen J

更新日期：2005-11-01 00:00:00

abstract：:Self-assembly is a prominent phenomenon observed in nature. Inspired by this thermodynamically favorable approach, several natural and synthetic materials have been investigated to develop functional systems for various biomedical applications, including drug delivery. Furthermore, layered self-assembled systems provi...

journal_title：Biomaterials

authors： Sarode A,Annapragada A,Guo J,Mitragotri S

更新日期：2020-02-29 00:00:00

abstract：:It has been widely accepted that lymph nodes (LNs) are critical targets of cancer vaccines and particles sized between 10 and 100 nm with a neutral or negative surface charge are preferred for lymphatic transfer after subcutaneous or intradermal injection. However their limited uptake by antigen presenting cells (APCs...

journal_title：Biomaterials

authors： Zeng Q,Li H,Jiang H,Yu J,Wang Y,Ke H,Gong T,Zhang Z,Sun X

更新日期：2017-04-01 00:00:00

abstract：:Poly(L-lactide) (PLLA) with an extremely high molecular weight (Mv up to 1 X 10(6)) was synthesized at a low catalyst concentration (0.015 wt%) and temperatures between 100-110 degrees C. Besides good mechanical properties the as-polymerized PLLA exhibited a microporous structure. Plates and screws of this material we...

journal_title：Biomaterials

authors： Leenslag JW,Pennings AJ,Bos RR,Rozema FR,Boering G

更新日期：1987-01-01 00:00:00

abstract：:Structural properties of several cross-linked hyaluronan derivatives, obtained by scanning electron microscopy, monodimensional NMR microscopy and small angle X-ray scattering of synchrotron radiation, are presented and compared with those observed for non-modified hyaluronic acid, used as a reference material. The ex...

journal_title：Biomaterials

authors： Gamini A,Paoletti S,Toffanin R,Micali F,Michielin L,Bevilacqua C

更新日期：2002-02-01 00:00:00

abstract：:There is a need for new therapeutic strategies to treat bone defects caused by trauma, disease or tissue loss. Injectable systems for cell transplantation have the advantage of allowing the use of minimally invasive surgical procedures, and thus for less discomfort to patients. In the present study, it is hypothesized...

journal_title：Biomaterials

authors： Evangelista MB,Hsiong SX,Fernandes R,Sampaio P,Kong HJ,Barrias CC,Salema R,Barbosa MA,Mooney DJ,Granja PL

更新日期：2007-09-01 00:00:00

abstract：:The formation of a confluent endothelium on expanded polytetrafluoroethylene (PTFE) vascular prostheses has never been observed. This lack of endothelialization is known to be one of the main reasons leading to the development of thromboses and/or intimal hyperplasia. In this context, several efforts were put forward ...

journal_title：Biomaterials

authors： Crombez M,Chevallier P,-Gaudreault RC,Petitclerc E,Mantovani D,Laroche G

更新日期：2005-12-01 00:00:00

abstract：:Hierarchical structured nanomaterials with diverse functionality, such as magnetic susceptibility, stimuli-responsiveness, environmental sensing and biocompatibility, are highly sought after for biomedicine and biodetection alike. In this study, we designed and fabricated a new kind of multifunctional core/shell nanos...

journal_title：Biomaterials

authors： Li D,Zhang YT,Yu M,Guo J,Chaudhary D,Wang CC

更新日期：2013-10-01 00:00:00

abstract：:The use of defined in vitro systems to study the developmental and physiological characteristics of a variety of cell types is increasing, due in large part to their ease of integration with tissue engineering, regenerative medicine, and high-throughput screening applications. In this study, myotubes derived from feta...

journal_title：Biomaterials

authors： Das M,Rumsey JW,Bhargava N,Stancescu M,Hickman JJ

更新日期：2009-10-01 00:00:00

abstract：:There is a growing demand for the production of a DNA biosensor with applications in medicine, the food industry, agriculture, veterinary science and environmental science. In this paper we describe methods for the optical and electrochemical detection of DNA using the enzyme horseradish peroxidase (EC 1.11.1.7) and g...

journal_title：Biomaterials

authors： Downs ME,Warner PJ,Turner AP,Fothergill JC

更新日期：1988-01-01 00:00:00

abstract：:Current approaches for topical vaginal administration of nanoparticles result in poor retention and extensive leakage. To overcome these challenges, we developed a nanoparticle-releasing nanofiber delivery platform and evaluated its ability to improve nanoparticle retention in a murine model. We individually tailored ...

journal_title：Biomaterials

authors： Krogstad EA,Ramanathan R,Nhan C,Kraft JC,Blakney AK,Cao S,Ho RJY,Woodrow KA

更新日期：2017-11-01 00:00:00

abstract：:We developed cell-free implants, comprising carbodiimide crosslinked recombinant human collagen (RHC), to enable corneal regeneration by endogenous cell recruitment, to address the worldwide shortage of donor corneas. Patients were grafted with RHC implants. Over four years, the regenerated neo-corneas were stably int...

journal_title：Biomaterials

authors： Fagerholm P,Lagali NS,Ong JA,Merrett K,Jackson WB,Polarek JW,Suuronen EJ,Liu Y,Brunette I,Griffith M

更新日期：2014-03-01 00:00:00