The mechanical properties of elastomeric poly(alkyl methacrylate)s.

abstract：:In human body ascorbic acid plays an essential role in the synthesis and function of skeletal tissues and immune system factors. Ascorbic acid is also a major physiological antioxidant, repairing oxidatively damaged biomolecules, preventing the formation of excessive reactive oxygen species or scavenging these species...

journal_title：Biomaterials

authors： Wang Y,Singh A,Xu P,Pindrus MA,Blasioli DJ,Kaplan DL

更新日期：2006-06-01 00:00:00

abstract：:The nanotopography and nanoscale geometry of the extra-cellular matrix (ECM) are important regulators of cell adhesion, motility and fate decision. However, unlike the sensing of matrix mechanics and ECM density, the molecular processes regulating the direct sensing of the ECM nanotopography and nanoscale geometry are...

journal_title：Biomaterials

authors： Di Cio S,Iskratsch T,Connelly JT,Gautrot JE

更新日期：2020-02-01 00:00:00

abstract：:Previous studies have shown that heterotopic induction of bone formation by calcium phosphate-based macroporous constructs is set into motion by the geometry of the implanted substrata, i.e. a sequence of repetitive concavities assembled within the macroporous spaces. The aim of this study was to construct osteoinduct...

journal_title：Biomaterials

authors： Ripamonti U,Roden LC,Renton LF

更新日期：2012-05-01 00:00:00

abstract：:Over the past two decades, in vitro autologous endothelial cell (EC) coverage of expanded polytetrafluoroethylene (ePTFE) graft has been developed and clinically applied with success in infrainguinal bypasses. Before endothelialization, the luminal surface of the graft has to be coated with a currently used fibrinolyt...

journal_title：Biomaterials

authors： Fernandez P,Deguette A,Pothuaud L,Belleannée G,Coste P,Bordenave L

更新日期：2005-08-01 00:00:00

abstract：:Parkinson's disease (PD) is one of the most common neurodegenerative diseases. Activins are members of the superfamily of transforming growth factors and have many potential neuroprotective effects. Herein, at the first place, we verified activin B's neuroprotective role in a PD model, and revealed that activin B's fa...

journal_title：Biomaterials

authors： Li J,Darabi M,Gu J,Shi J,Xue J,Huang L,Liu Y,Zhang L,Liu N,Zhong W,Zhang L,Xing M,Zhang L

更新日期：2016-09-01 00:00:00

abstract：:A nucleus pulposus prosthesis (NPP) made of the hydrogel N-vinyl-2-pyrrolidinone copolymerized with 2-(4'-iodobenzoyl)-oxo-ethyl methacrylate has recently been developed. The special features of this NPP, i.e. intrinsic radiopacity and its ability to swell in situ to fill the nucleus cavity and restore disc height, we...

journal_title：Biomaterials

authors： Bergknut N,Smolders LA,Koole LH,Voorhout G,Hagman RE,Lagerstedt AS,Saralidze K,Hazewinkel HA,van der Veen AJ,Meij BP

更新日期：2010-09-01 00:00:00

abstract：:Magnesium (Mg), a potential biodegradable material, has recently received increasing attention due to its unique antibacterial property. However, rapid corrosion in the physiological environment and potential toxicity limit clinical applications. In order to improve the corrosion resistance meanwhile not compromise th...

journal_title：Biomaterials

authors： Qin H,Zhao Y,An Z,Cheng M,Wang Q,Cheng T,Wang Q,Wang J,Jiang Y,Zhang X,Yuan G

更新日期：2015-06-01 00:00:00

abstract：:The clinical application of cancer radiotherapy is critically impeded by hypoxia-induced radioresistance, insufficient DNA damage, and multiple DNA repair mechanisms. Herein we demonstrate a dual-hyperthermia strategy to potentiate radiotherapy by relieving tumor hypoxia and preventing irradiation-induced DNA damage r...

journal_title：Biomaterials

authors： Li Q,Hang L,Jiang W,Dou J,Xiao L,Tang X,Yao Y,Wang Y

更新日期：2020-10-01 00:00:00

abstract：:The oriented attachment of hydroxyapatite (HAP) nanorods was achieved through a hydrothermal treatment. The nanorods were arranged in order along the c-axis of the HAP. These formed ca. 3.5 slip-shaped pores between the rods. High-resolution transmission electron (HRTEM) also revealed that single crystals of HAP may g...

journal_title：Biomaterials

authors： Chen JD,Wang YJ,Wei K,Zhang SH,Shi XT

更新日期：2007-05-01 00:00:00

abstract：:The in vivo performance of 250 retrieved internal fixation plates was evaluated. The corrosion characteristics and metallurgical properties of each implant were assessed and correlated with respective clinical performance. Screw-plate interface corrosion and screw surface corrosion were graded; Rockwell hardness, grai...

journal_title：Biomaterials

authors： Cook SD,Thomas KA,Harding AF,Collins CL,Haddad RJ Jr,Milicic M,Fischer WL

更新日期：1987-05-01 00:00:00

abstract：:Despite being increasingly used as artificial enzymes, little has been known for the origin of the pH-switchable peroxidase-like and catalase-like activities of metals. Using calculations and experiments, we report the mechanisms for both activities and their pH-switchability for metals Au, Ag, Pd and Pt. The calculat...

journal_title：Biomaterials

authors： Li J,Liu W,Wu X,Gao X

更新日期：2015-04-01 00:00:00

abstract：:Lesions in the avascular part of 20 canine menisci were repaired by implantation of a porous polyurethane. Seven menisci were not repaired and served as controls. The repair tissue was characterized by biochemical and immunological analysis. The role of vascularity in healing was studied by perfusion of menisci with I...

journal_title：Biomaterials

authors： Klompmaker J,Veth RP,Jansen HW,Nielsen HK,de Groot JH,Pennings AJ,Kuijer R

更新日期：1996-09-01 00:00:00

abstract：:In addition to unidirectional laminates and short fiber reinforcements for compression bone plate developments in the literature, we have proposed using a textile structure, i.e. braid preform, for this purpose. In the present paper, the influence of braiding angles and plate thicknesses on the bending performance of ...

journal_title：Biomaterials

authors： Fujihara K,Huang ZM,Ramakrishna S,Satknanantham K,Hamada H

更新日期：2003-07-01 00:00:00

abstract：:Biological heart prostheses present medium and long-term problems, owing to progressive deterioration and calcification of the tissue. To study the latter problem, we compared the effectiveness of anticalcification treatments in calf pericardium samples implanted into female Wistar rats after the following procedures:...

journal_title：Biomaterials

authors： Jorge-Herrero E,Gutiérrez MP,Castillo-Olivares JL

更新日期：1991-03-01 00:00:00

abstract：:A major role of respiratory mucus is to trap inhaled particles, including pathogens and environmental particulates, to limit body exposure. Despite the tremendous health implications, how particle size and surface chemistry affect mobility in respiratory mucus from humans without lung disease is not known. We prepared...

journal_title：Biomaterials

authors： Schuster BS,Suk JS,Woodworth GF,Hanes J

更新日期：2013-04-01 00:00:00

abstract：:Nanotherapeutics have been investigated for years, but only modest survival benefits were observed clinic. This is partially attributed to the short and rapid elimination of nanodrug after intravenous administration. In this study, a long circulation single wall carbon nanotube (SWCNT) complex was successfully fabrica...

journal_title：Biomaterials

authors： Xie L,Wang G,Zhou H,Zhang F,Guo Z,Liu C,Zhang X,Zhu L

更新日期：2016-10-01 00:00:00

abstract：:Artificial meniscal lesions extending into the avascular part of the meniscus, which do not heal by any other means, were repaired by suturing either a porous polymer implant or a synovial flap into the defect. The implant guided the ingrowth of vascular repair tissue into the defect. This fibrous tissue later on tran...

journal_title：Biomaterials

authors： Klompmaker J,Jansen HW,Veth RP,de Groot JH,Nijenhuis AJ,Pennings AJ

更新日期：1991-11-01 00:00:00

abstract：:Breast cancer is associated with high mortality due to tumor metastasis. The anti-metastasis efficacy of photochemotherapy is strictly limited by poor targeting capability with respect to circulating tumor cells (CTCs) in blood and lymph. Herein, we decorate the platelet membrane (PM) on a surface of nanoparticles (NP...

journal_title：Biomaterials

authors： Ye H,Wang K,Wang M,Liu R,Song H,Li N,Lu Q,Zhang W,Du Y,Yang W,Zhong L,Wang Y,Yu B,Wang H,Kan Q,Zhang H,Wang Y,He Z,Sun J

更新日期：2019-06-01 00:00:00

abstract：:Titanium implants have been used widely and successfully for various types of bone-anchored reconstructions. It is believed that properties of oxide films covering titanium implant surfaces are of crucial importance for a successful osseointegration, in particular at compromized bone sites. The aim of the present stud...

journal_title：Biomaterials

authors： Sul YT,Johansson CB,Petronis S,Krozer A,Jeong Y,Wennerberg A,Albrektsson T

更新日期：2002-01-01 00:00:00

abstract：:A cardiomyocyte-targeted Fas siRNA delivery system was developed using prostaglandin E(2) (PGE(2))-modified siRNA polyplexes formed by a reducible poly(amido amine) to inhibit cardiomyocyte apoptosis. PGE(2), which was used as a specific ligand for cardiomyocyte targeting, was conjugated to the terminal-end of the sen...

journal_title：Biomaterials

authors： Kim SH,Jeong JH,Ou M,Yockman JW,Kim SW,Bull DA

更新日期：2008-11-01 00:00:00

abstract：:The advancement in gene therapy relies upon the discovery of safe and efficient delivery agents and methods. In this study, we report the design and synthesis of a cationic bolaamphiphile as a non-viral gene delivery agent. The bolaamphiphile is composed of 1,12-diaminododecane as the central hydrophobic unit linked t...

journal_title：Biomaterials

authors： Khan M,Ang CY,Wiradharma N,Yong LK,Liu S,Liu L,Gao S,Yang YY

更新日期：2012-06-01 00:00:00

abstract：:Helicobacter pylori is a significant human pathogen that recognizes specific carbohydrate receptors, such as the fucose receptor, and produces the vacuolating cytotoxin, which induces inflammatory responses and modulates the cell-cell junction integrity of the gastric epithelium. The clinical applicability of topical ...

journal_title：Biomaterials

authors： Lin YH,Tsai SC,Lai CH,Lee CH,He ZS,Tseng GC

更新日期：2013-06-01 00:00:00

abstract：:The effect of inclusion of an immobilization matrix and the capsule membrane permeability on the viability, metabolic activity, and proliferation of encapsulated HEK cells was investigated in vitro. In the absence of a matrix, a particular transfected HEK cell line formed a single aggregate in the core of the poly(hyd...

journal_title：Biomaterials

authors： Lahooti S,Sefton MV

更新日期：2000-05-01 00:00:00

abstract：:Two types of cells--human platelets and spore cells--were encapsulated in polymer shells by adsorbing polyanions and polycations in a stepwise fashion. The encapsulated cells were attached to gold and silicon surfaces and their morphological and adhesion properties were studied in air using tapping mode atomic force m...

journal_title：Biomaterials

authors： Yu M,Ivanisevic A

更新日期：2004-08-01 00:00:00

abstract：:Intestinal organoids are widely applied in stem cell research, regenerative medicine, toxicology, pharmacology, and host-microbe interactions research. The variability of oxidative metabolism for stem and differentiated cell types constituting organoid is known to be important but so far it has not been studied in det...

journal_title：Biomaterials

authors： Okkelman IA,Foley T,Papkovsky DB,Dmitriev RI

更新日期：2017-11-01 00:00:00

abstract：:Self-assembly is a prominent phenomenon observed in nature. Inspired by this thermodynamically favorable approach, several natural and synthetic materials have been investigated to develop functional systems for various biomedical applications, including drug delivery. Furthermore, layered self-assembled systems provi...

journal_title：Biomaterials

authors： Sarode A,Annapragada A,Guo J,Mitragotri S

更新日期：2020-02-29 00:00:00

abstract：:We have developed an ion-sensing nanoparticle that is comprised of a superparamagnetic iron oxide (SPIO) core encapsulated with a porous silica shell. The latter can be readily anchored with ligands capable of coordinating with positron-emitting metal. Evidently, this nanoparticle has a great potential for use in cell...

journal_title：Biomaterials

authors： Patel D,Kell A,Simard B,Deng J,Xiang B,Lin HY,Gruwel M,Tian G

更新日期：2010-04-01 00:00:00

abstract：:Implant-associated infections represent a significant health problem and financial burden on healthcare systems. Current strategies for the treatment or prevention of such infections are still inadequate and new strategies are needed in this era of antibiotic resistance. Melimine, a synthetic antimicrobial peptide wit...

journal_title：Biomaterials

authors： Chen R,Willcox MD,Ho KK,Smyth D,Kumar N

更新日期：2016-04-01 00:00:00

abstract：:The maximum capacity of a hydrophobic adsorbent is interpreted in terms of square or hexagonal (cubic and face-centered-cubic, FCC) interfacial packing models of adsorbed blood proteins in a way that accommodates experimental measurements by the solution-depletion method and quartz-crystal-microbalance (QCM) for the h...

journal_title：Biomaterials

authors： Kao P,Parhi P,Krishnan A,Noh H,Haider W,Tadigadapa S,Allara DL,Vogler EA

更新日期：2011-02-01 00:00:00

abstract：:It is estimated that 4 to 5 million people are currently co-infected with Human Immunodeficiency Virus (HIV) and Hepatitis C Virus (HCV). HIV/HCV co-infection is associated with unique health risks including increased hepatotoxicity of antiretrovirals, accelerated progression of HCV and liver diseases. The standard in...

journal_title：Biomaterials

authors： Zhang J,Mulvenon A,Makarov E,Wagoner J,Knibbe J,Kim JO,Osna N,Bronich TK,Poluektova LY

更新日期：2013-05-01 00:00:00