Tantalum-loaded polyurethane microspheres for particulate embolization: preparation and properties.

abstract：:Arterial catheterization is one of the most frequently performed inpatient diagnostic and therapeutic procedures in the development countries. Complications may occur after any catheterization from inadequate hemostasis, particularly in the setting of aggressive anticoagulation. This study suggests that microcrystalli...

journal_title：Biomaterials

authors： Hoekstra A,Struszczyk H,Kivekäs O

更新日期：1998-08-01 00:00:00

abstract：:Electrically conducting polymers hold promise for developing advanced neuroprostheses, bionic systems and neural repair devices. Among them, poly(3, 4-ethylenedioxythiophene) doped with polystyrene sulfonate (PEDOT:PSS) exhibits superior physicochemical properties but biocompatibility issues have limited its use. We d...

journal_title：Biomaterials

authors： Collazos-Castro JE,Polo JL,Hernández-Labrado GR,Padial-Cañete V,García-Rama C

更新日期：2010-12-01 00:00:00

abstract：:The rationale behind this work is to design an implant device, based on a ferromagnetic material, with the potential to deform in vivo promoting osseointegration through the growth of a healthy periprosthetic bone structure. One of the primary requirements for such a device is that the material should be non-inflammat...

journal_title：Biomaterials

authors： Malheiro VN,Spear RL,Brooks RA,Markaki AE

更新日期：2011-10-01 00:00:00

abstract：:Keratins are a family of structural proteins that can be isolated from a variety of tissues. "Soft" keratins are cytoskeletal elements found in epithelial tissues while protective tissues such as nails, hooves, and hair are composed of "hard" keratins. Hard keratins have been the subject of biomaterials investigations...

journal_title：Biomaterials

authors： Hill P,Brantley H,Van Dyke M

更新日期：2010-02-01 00:00:00

abstract：:Four commercial hydroxyapatites (both natural and synthetic) were tested to assess transformations of the chemical and crystalline structure following variation of temperature from 20 to 1600 degrees C. The thermal behaviour of hydroxyapatite is relevant for biomedical applications such as plasma spraying of metallic ...

journal_title：Biomaterials

authors： Locardi B,Pazzaglia UE,Gabbi C,Profilo B

更新日期：1993-05-01 00:00:00

abstract：:Calcium phosphate (CaP) based approaches remain an attractive option for delivering plasmid DNA (pDNA) into cultured cells. However, despite their appeal, current synthesis methodologies typically yield lower, less consistent transfection efficiencies when compared to viral approaches. Therefore, we report here a nove...

journal_title：Biomaterials

authors： Olton D,Li J,Wilson ME,Rogers T,Close J,Huang L,Kumta PN,Sfeir C

更新日期：2007-02-01 00:00:00

abstract：:Although folate exhibits many advantages over other targeting ligands, it has one major defect: poor water solubility. Once it was conjugated to hydrophilic drug carrier such as N-(2-hydroxypropyl) methacrylamide (HPMA) copolymer, the hydrophobic folate may be buried inside the random polymer coil and not exposed to b...

journal_title：Biomaterials

authors： Li L,Yang Q,Zhou Z,Zhong J,Huang Y

更新日期：2014-06-01 00:00:00

abstract：:Coralline hydroxyapatite ceramics alone (control) and the ceramics combined with rat marrow cells were implanted subcutaneously in the backs of syngeneic Fischer rats and harvested at 1,2,3,4,6,8 and 24 wk after surgery. None of the control ceramics (without marrow) showed bone formation. However, ceramics combined wi...

journal_title：Biomaterials

authors： Okumura M,Ohgushi H,Tamai S

更新日期：1991-05-01 00:00:00

abstract：:Previous work developing particle-based acellular, artificial antigen presenting cells (aAPCs) has focused exclusively on spherical platforms. To explore the role of shape, we generated ellipsoidal PLGA microparticles with varying aspect ratios (ARs) and synthesized aAPCs from them. The ellipsoidal biomimetic aAPCs wi...

journal_title：Biomaterials

authors： Sunshine JC,Perica K,Schneck JP,Green JJ

更新日期：2014-01-01 00:00:00

abstract：:Nitric oxide (NO) is an important biological messenger involved in the treatment of bacterial infections, but its controlled and targeted release in bacterial infections remains a major challenge. Herein, an intelligent NO nanogenerator triggered by near-infrared (NIR) light is constructed for targeted treatment of P....

journal_title：Biomaterials

authors： Wu Y,Deng G,Jiang K,Wang H,Song Z,Han H

更新日期：2021-01-01 00:00:00

abstract：:The efficacy of colloidal particles as drug carriers is closely related to their interaction with proteins and enzymes in different body fluids. In the present work, we analysed the interaction phenomenon between lysozyme (LZM), a positively charged enzyme that is highly concentrated in mucosas, and two different drug...

journal_title：Biomaterials

authors： Calvo P,Vila-Jato JL,Alonso MJ

更新日期：1997-10-01 00:00:00

abstract：:Effect of poly(epsilon-caprolactone) (PCL) content on the bioactivity and mechanical properties of PCL/silica hybrid was investigated. The PCL/silica hybrids with different PCL contents were prepared through co-condensation reaction with triethoxysilane end capped PCL and tetraethyl orthosilicate. The higher the PCL c...

journal_title：Biomaterials

authors： Rhee SH

更新日期：2004-03-01 00:00:00

abstract：:Bioactive composites composed of hydroxyapatite containing glass (HA-G) as a coating and titanium (Ti) or titanium alloy implants as a substrate were prepared by the Cullet method. This method results in the HA-G coating layer on the substrate with a compositional gradient in HA concentration. The results of in vitro ...

journal_title：Biomaterials

authors： Yamada K,Imamura K,Itoh H,Iwata H,Maruno S

更新日期：2001-08-01 00:00:00

abstract：:Stress urinary incontinence (SUI) is an embarrassing problem affecting a large number of women and interfering with their quality of life. The injury or weakness of urethral supporting tissues by childbirth and aging has been considered as key factors in the development of the SUI. In this study, plasmid DNA (pDNA; en...

journal_title：Biomaterials

authors： Choi SJ,Oh SH,Kim IG,Chun SY,Lee JY,Lee JH

更新日期：2013-07-01 00:00:00

abstract：:This paper presents some results concerning the size-controlled hydroxyapatite nanoparticles obtained in aqueous media in a biopolymer matrix from soluble precursors salts. Taking the inspiration from nature, where composite materials made of a polymer matrix and inorganic fillers are often found, e.g. bone, shell of ...

journal_title：Biomaterials

authors： Rusu VM,Ng CH,Wilke M,Tiersch B,Fratzl P,Peter MG

更新日期：2005-09-01 00:00:00

abstract：:Hydroxyapatite (HAP) cement was implanted in the femur of rats with experimentally induced osteoporosis, and the osteogenic response was studied histomorphologically. Osteoporosis was induced with ovariectomy with either a normal diet or a low-calcium diet. The rats fed a low-calcium diet after ovariectomy showed a de...

journal_title：Biomaterials

authors： Saito T,Kin Y,Koshino T

更新日期：2002-07-01 00:00:00

abstract：:Mandibular reconstruction requires functional and aesthetic repair and is further complicated by contamination from oral and skin flora. Antibiotic-releasing porous space maintainers have been developed for the local release of vancomycin and to promote soft tissue attachment. In this study, mandibular defects in six ...

journal_title：Biomaterials

authors： Watson E,Smith BT,Smoak MM,Tatara AM,Shah SR,Pearce HA,Hogan KJ,Shum J,Melville JC,Hanna IA,Demian N,Wenke JC,Bennett GN,van den Beucken JJJP,Jansen JA,Wong ME,Mikos AG

更新日期：2020-10-01 00:00:00

abstract：:Using the recently developed surface modification technique, free amino groups have been introduced onto polyester-type polyurethane (PU) scaffolds. The introduction of these free amino groups increases the surface energy and provides a convenient way to further immobilize bioactive species such as gelatin, collagen o...

journal_title：Biomaterials

authors： Zhu Y,Gao C,He T,Shen J

更新日期：2004-02-01 00:00:00

abstract：:Leveraging the multifunctional nature of citrate in chemistry and inspired by its important role in biological tissues, a class of highly versatile and functional citrate-based materials (CBBs) has been developed via facile and cost-effective polycondensation. CBBs exhibiting tunable mechanical properties and degradat...

journal_title：Biomaterials

authors： Ma C,Gerhard E,Lu D,Yang J

更新日期：2018-09-01 00:00:00

abstract：:A rapid and simple in vitro method is described which measures the extent of unrecoiled solids compression when a complex biopolymer is subjected to a centrifugal force. This method, termed the compaction assay, was used to assess the response of purulent cystic fibrosis (CF) sputum samples to the addition of recombin...

journal_title：Biomaterials

authors： Daugherty AL,Patapoff TW,Clark RC,Sinicropi DV,Mrsny RJ

更新日期：1995-05-01 00:00:00

abstract：:The immune system is a powerful resource for the eradication of cancer, but to overcome the low immunogenicity of tumor cells, a sufficiently strong CD8(+) T cell-mediated adaptive immune response is required. Nanoparticulate biomaterials represent a potentially effective delivery system for cancer vaccines, as they c...

journal_title：Biomaterials

authors： Molino NM,Neek M,Tucker JA,Nelson EL,Wang SW

更新日期：2016-04-01 00:00:00

abstract：:Plaque-induced lesions can produce peri-implant bone loss with ultimate implant loss. Although the peri-implant tissues seem to be more resistant than the periodontal ones to plaque and calculus, they can produce a more extensive spread of the infection to the deeper tissues around implants. The case of a 45-year-old ...

journal_title：Biomaterials

authors： Piattelli A,Cosci F,Scarano A,Trisi P

更新日期：1995-08-01 00:00:00

abstract：:Recent studies suggest that bone marrow stromal cells are a potential source of osteoblasts and chondrocytes and can be used to regenerate damaged tissues using a tissue-engineering (TE) approach. However, these strategies require the use of an appropriate scaffold architecture that can support the formation de novo o...

journal_title：Biomaterials

authors： Oliveira JM,Rodrigues MT,Silva SS,Malafaya PB,Gomes ME,Viegas CA,Dias IR,Azevedo JT,Mano JF,Reis RL

更新日期：2006-12-01 00:00:00

abstract：:For chronic non-viral gene therapy, biodegradable carriers with low cytotoxicity are essential. To create a series of non-toxic and biodegradable gene carriers, hyperbranched polymers based on 2,2-bis-(methylol)propionic acid (bis-MPA); (Boltorn H) were modified by introducing tertiary amines. The terminal OH groups w...

journal_title：Biomaterials

authors： Reul R,Nguyen J,Kissel T

更新日期：2009-10-01 00:00:00

abstract：:The superelastic nature of bones requires matching biomechanical properties from the ideal artificial biomedical implants in order to provide smooth load transfer and foster the growth of new bone tissues. In this work, we determine the biomechanical characteristics of porous NiTi implants and investigate bone ingrowt...

journal_title：Biomaterials

authors： Liu X,Wu S,Yeung KW,Chan YL,Hu T,Xu Z,Liu X,Chung JC,Cheung KM,Chu PK

更新日期：2011-01-01 00:00:00

abstract：:Previous studies have shown that heterotopic induction of bone formation by calcium phosphate-based macroporous constructs is set into motion by the geometry of the implanted substrata, i.e. a sequence of repetitive concavities assembled within the macroporous spaces. The aim of this study was to construct osteoinduct...

journal_title：Biomaterials

authors： Ripamonti U,Roden LC,Renton LF

更新日期：2012-05-01 00:00:00

abstract：:A photografting technique to produce functional groups of silanol able to induce apatite nucleation was attempted on polyethylene substrate for biomimetic formation of bone-mineral-like apatite layer on its surface. The polyethylene surface was subjected to vapor-phase photografting of vinyltrimethoxysilane and subseq...

journal_title：Biomaterials

authors： Kim HM,Uenoyama M,Kokubo T,Minoda M,Miyamoto T,Nakamura T

更新日期：2001-09-01 00:00:00

abstract：:Traditional biochemistry of contact activation of blood coagulation suggesting that anionic hydrophilic surfaces are specific activators of the cascade is inconsistent with known trends in protein adsorption. To investigate contact activation reactions, a chromogenic assay was used to measure prekallkrein (PK) hydroly...

journal_title：Biomaterials

authors： Chatterjee K,Thornton JL,Bauer JW,Vogler EA,Siedlecki CA

更新日期：2009-10-01 00:00:00

abstract：:Construction of biodegradable, three-dimensional scaffolds for tissue engineering has been previously described using a variety of molding and rapid prototyping techniques. In this study, we report and compare two methods for fabricating poly(DL-lactide-co-glycolide) (PLGA) scaffolds with feature sizes of approximatel...

journal_title：Biomaterials

authors： Vozzi G,Flaim C,Ahluwalia A,Bhatia S

更新日期：2003-06-01 00:00:00

abstract：:We report here the study of the biocompatibility of a bone graft material, the Pyrost, using a previously established in vitro model of human osteoblasts. The effect of this material on cell proliferation was evaluated by the MTS assay. Results indicated the absolute absence of cytotoxic or cytostatic effect of Pyrost...

journal_title：Biomaterials

authors： Josset Y,Oum'hamed Z,Zarrinpour A,Lorenzato M,Adnet JJ,Laurent-Maquin D

更新日期：1998-10-01 00:00:00