Abstract：
:Hydroxyapatite (HAP) cement was implanted in the femur of rats with experimentally induced osteoporosis, and the osteogenic response was studied histomorphologically. Osteoporosis was induced with ovariectomy with either a normal diet or a low-calcium diet. The rats fed a low-calcium diet after ovariectomy showed a decrease in both cumulative photodensity and the cortical thickness index. There was significant bone conduction in the femur of these rats, but the development of new bone was late, and the affinity index was small. The change in the affinity index with time was similar between the ovariectomy group and the ovariectomy/low calcium-group, suggesting the possibility that estrogen plays a major role in bone conduction.
journal_name
Biomaterialsjournal_title
Biomaterialsauthors
Saito T,Kin Y,Koshino Tdoi
10.1016/s0142-9612(02)00003-0keywords:
subject
Has Abstractpub_date
2002-07-01 00:00:00pages
2711-6issue
13eissn
0142-9612issn
1878-5905pii
S0142-9612(02)00003-0journal_volume
23pub_type
杂志文章相关文献
BIOMATERIALS文献大全abstract：:Silk fibers have potential biomedical applications beyond their traditional use as sutures. The physical properties of silk fibers and films make it a promising candidate for tissue engineering scaffold applications, particularly where high mechanical loads or tensile forces are applied or in cases where low rates of ...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/s0142-9612(03)00158-3
更新日期：2003-08-01 00:00:00
abstract：:The efficient delivery of short interfering RNA (siRNA) is an enormous challenge in the field of gene therapy. Herein, we report a delivery nanosystem based on programmed DNA self-assembly mammalian target of rapamycin (mTOR) siRNA-loaded DNA nanotubes (DNA-NTs). We demonstrate that these siRNA-DNA-NTs can be effectiv...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/j.biomaterials.2015.07.015
更新日期：2015-10-01 00:00:00
abstract：:A multifunctional organic-inorganic hybrid nanocapsule based on Bi2S3-embedded poly (lactic-co-glycolic acid) (PLGA) nanocapsule has been elaborately designed to combine the merits of both polymeric shell structure and Bi2S3 nanoparticles. Hydrophobic Bi2S3 nanoparticles were successfully introduced into the PLGA nano...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/j.biomaterials.2014.06.010
更新日期：2014-09-01 00:00:00
abstract：:Type I collagen constitutes a major portion of the extracellular matrix (ECM) in arterial wall and it is the major substrate for cell growth and differentiation. The goal of this study was to evaluate the differentiation and proliferation of placenta-derived multipotent cells (PDMCs) on polymerized type I collagen fib...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/j.biomaterials.2010.02.011
更新日期：2010-05-01 00:00:00
abstract：:The aim of this study, in rabbit tibia, was an evaluation of the early reactions of the tissues to the insertion of polylactic membranes, used in connection with titanium implants. The specimens were retrieved after 1-4 weeks, and a histological analysis was performed. It was possible to see that, in the early implant...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/s0142-9612(97)00173-7
更新日期：1998-05-01 00:00:00
abstract：:Current tissue engineering strategies are focused on the restoration of pathologically altered tissue architecture by transplantation of cells in combination with supportive scaffolds and biomolecules. In recent years, considerable attention has been given to chitosan (CS)-based materials and their applications in the...
journal_title：Biomaterials
pub_type： 杂志文章,评审
doi：10.1016/j.biomaterials.2005.03.016
更新日期：2005-10-01 00:00:00
abstract：:A series of mesoporous silica nanoparticles (MSNs) were synthesized using the co-structure directing method. A non-cytotoxic anionic surfactant, undec-1-en-11-yltetra(ethylene glycol) phosphate monoester surfactant (PMES), was used as a structure directing agent (SDA) together with aminopropyltrimethoxysilane that fun...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/j.biomaterials.2011.04.077
更新日期：2011-09-01 00:00:00
abstract：:Biocompatibility and tissue regenerating capacity are essential characteristics in the design of collagenous biomaterials for tissue engineering. Attachment of glycosaminoglycans (GAGs) to collagen may add to these characteristics by creating an appropriate micro-environment. In this study, porous type I collagen matr...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/s0142-9612(00)00052-1
更新日期：2000-08-01 00:00:00
abstract：:This is the first report on a series of studies of the crystallinity of bone tissues. The measurements were done at the microfocused diffraction beamline at ERSF (European Synchrotron Radiation Facility) as a feasibility test on various aspects on microdiffraction analysis. Beside the crystal structure, crystallite si...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/s0142-9612(98)00120-3
更新日期：1998-11-01 00:00:00
abstract：:Drug-loaded implants have attracted considerable attention in cancer treatment due to their precise delivery of drugs into cancer tissues. Contrary to injected drug delivery, the application of drug-loaded implants remains underutilized given the requirement for a surgical operation. Nevertheless, drug-loaded implants...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/j.biomaterials.2019.119618
更新日期：2020-02-01 00:00:00
abstract：:This study was undertaken to evaluate the influence of storage conditions on the shelf-life of porcine bioprosthetic valves. Fifty-five unimplanted porcine bioprostheses have been evaluated. The valves were stored in 0.5% buffered glutaraldehyde solution for different periods of time (7, 23 and 32 months). Twenty-eigh...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/s0142-9612(96)00155-x
更新日期：1997-04-01 00:00:00
abstract：:Lymphocytes typically interact with implanted biomaterials through adsorbed exogenous proteins. To provide a more complete characterization of these interactions, analysis of lymphocyte migration on adsorbed extracellular matrix proteins must accompany the commonly performed adhesion studies. We report here a comparis...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/s0142-9612(99)00154-4
更新日期：1999-12-01 00:00:00
abstract：:The influence of crystallization, upon heat treatment, on the properties of high-velocity oxy-fuel (HVOF) sprayed hydroxyapatite (HA) coatings was investigated. The characterization of the HA coating was performed by X-ray diffraction (XRD) and Fourier Transform Infrared Spectroscopy (FTIR). Differential Scanning Calo...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/s0142-9612(01)00326-x
更新日期：2002-05-01 00:00:00
abstract：:Fibronectin (Fn) forms a fibrillar network that controls cell behavior in both physiological and diseased conditions including cancer. Indeed, breast cancer-associated stromal cells not only increase the quantity of deposited Fn but also modify its conformation. However, (i) the interplay between mechanical and confor...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/j.biomaterials.2015.03.019
更新日期：2015-06-01 00:00:00
abstract：:Infection constitutes a major risk for implant failure, but the reasons why biomaterial sites are more vulnerable than normal tissue are not fully elucidated. In this study, a soft tissue infection model was developed, allowing the analysis of cellular and molecular responses in each of the sub-compartments of the imp...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/j.biomaterials.2014.11.032
更新日期：2015-02-01 00:00:00
abstract：:To broaden the clinical application of cartilage regenerative medicine, we should develop an implant-type tissue-engineered cartilage with firmness and 3-D structure. For that, we attempted to use a porous biodegradable polymer scaffold in the combination with atelocollagen hydrogel, and optimized the structure and co...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/j.biomaterials.2010.02.028
更新日期：2010-06-01 00:00:00
abstract：:High-throughput screening techniques for cellular response are often unable to account for several factors present in the in vivo environment, many of which have been shown to modulate cellular response to the screened parameter. Culture in three-dimensional biomaterials and active mechanical stimulation are two such ...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/j.biomaterials.2009.09.068
更新日期：2010-01-01 00:00:00
abstract：:We have used a new synthetic injectable composite constituted of hydroxyapatite/tricalcium phosphate (HA/TCP) particles in suspension in a self-hardening Si-hydroxypropylmethylcellulose (HPMC) hydrogel. The aim of this study was to evaluate in vivo the biocompatibility and the new bone formation efficacy of this scaff...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/j.biomaterials.2006.01.057
更新日期：2006-06-01 00:00:00
abstract：:We investigated the hypothesis that immobilizing TGF-β1 within fibrin hydrogels may act in synergy with cyclic mechanical stimulation to enhance the properties of vascular grafts. To this end, we engineered a fusion TGF-β1 protein that can covalently anchor to fibrin during polymerization upon the action of factor XII...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/j.biomaterials.2013.05.073
更新日期：2013-10-01 00:00:00
abstract：:Smad3 mediates the intracellular signaling of TGF-beta1 superfamily and plays a critical role in the cellular proliferation, differentiation and elaboration of matrix pivotal to cutaneous wound healing. Smad3 antisense oligonucleotides (ASOs) impregnated polyelectrolyte complex (PEC) containing chitosan and sodium alg...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/j.biomaterials.2008.08.023
更新日期：2008-12-01 00:00:00
abstract：:The iron-containing fluoridated hydroxyapatites Fe-FeFAp and FeF-FeAp were synthesized heterogeneously in the presence of ferrous ions at 80 degrees C and pH 7.4 in two different types of solution, i.e. fluoride-free solution during the initial half of the experimental period and fluoride-containing solution during th...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/s0142-9612(96)00094-4
更新日期：1997-01-01 00:00:00
abstract：:Random copolymers of trimethylene carbonate and epsilon-caprolactone have been synthesized through ring-opening polymerization using rare earth alkoxides as initiator. The structure of the copolymers has been characterized by 1H and 13C NMR. Their thermal behaviour, their permeability to liquid and their mechanical pr...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/s0142-9612(01)00029-1
更新日期：2001-11-01 00:00:00
abstract：:This work describes the use of aqueous two-phase systems to print cell-containing contractile collagen microdroplets. The fully aqueous conditions enable convenient formation of sub-microliter 'microgels' that are much smaller than otherwise possible to fabricate while maintaining high cell viability. The produced mic...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/j.biomaterials.2013.08.046
更新日期：2013-12-01 00:00:00
abstract：:The micro-environment is an important factor in the differentiation of cultured stem cells for the purpose of site specific transplantation. In an attempt to optimize differentiation conditions, co-culture systems composed of both stem cells and primary cells or cell lines were used in hydrogel with in vitro and in vi...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/j.biomaterials.2010.06.006
更新日期：2010-10-01 00:00:00
abstract：:Multidrug resistance (MDR) remains one of the major reasons for the reductions in efficacy of many chemotherapeutic agents in cancer therapy. As a classical MDR phenotype of human malignancies, the adenosine triphosphate binding cassette (ABC)-transporter P-glycoprotein (MDR1/P-gp) is an efflux protein with aberrant a...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/j.biomaterials.2014.12.030
更新日期：2015-03-01 00:00:00
abstract：:Photosensitizers with aggregation-induced emission (AIE) characteristics are of great interest for cancer theranostics involving both fluorescence imaging and photodynamic therapy (PDT). However, in the purpose of clinical trials of PDT, the development of prominent drug delivery systems for boosting the PDT efficienc...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/j.biomaterials.2019.119749
更新日期：2020-02-01 00:00:00
abstract：:We report here the study of the biocompatibility of a bone graft material, the Pyrost, using a previously established in vitro model of human osteoblasts. The effect of this material on cell proliferation was evaluated by the MTS assay. Results indicated the absolute absence of cytotoxic or cytostatic effect of Pyrost...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/s0142-9612(98)00090-8
更新日期：1998-10-01 00:00:00
abstract：:Menisci are one of the most commonly injured parts of the knee with a limited healing potential. This study focuses on fabrication and characterization of biomimetic surfaces for meniscal tissue engineering. To achieve this, a combination of hyaluronic acid/chitosan (HA/CH) mutilayers with covalently immobilized major...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/j.biomaterials.2010.04.018
更新日期：2010-08-01 00:00:00
abstract：:One of the key challenges for neural tissue engineering is to exploit supporting materials with robust functionalities not only to govern cell-specific behaviors, but also to form functional neural network. The unique electrical and mechanical properties of graphene imply it as a promising candidate for neural interfa...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/j.biomaterials.2013.05.024
更新日期：2013-09-01 00:00:00
abstract：:By use of scanning electron microscopy (SEM), together with energy dispersive chemical analysis, a study has been made of the comparison of an in vitro method of assessing interface reactions between bone and ceramic implants with the naturally occurring changes seen in the rat ear model. Interface reactions between b...
journal_title：Biomaterials
pub_type： 杂志文章
doi：10.1016/0142-9612(85)90024-9
更新日期：1985-07-01 00:00:00
