The proliferation and differentiation of placental-derived multipotent cells into smooth muscle cells on fibrillar collagen.

abstract：:Quinacrine and related heterocyclic compounds have antiprion activity. Since the infectious pathogen of prion diseases is composed of multimeric PrP(Sc) assemblies, we hypothesized that this antiprion property could be enhanced by attaching multiple quinacrine-derived chloroquinoline or acridine moieties to a scaffold...

journal_title：Biomaterials

authors： Mays CE,Joy S,Li L,Yu L,Genovesi S,West FG,Westaway D

更新日期：2012-10-01 00:00:00

abstract：:Osteoclasts resorb bone at surfaces, leaving behind pits and trails where both mineral and organic phases of bone have been dissolved. Rough surface structures are deliberately imparted to synthetic implants, in order to improve osseointegration. The aim of this study is to characterize osteoclastic resorption pits on...

journal_title：Biomaterials

authors： Hefti T,Frischherz M,Spencer ND,Hall H,Schlottig F

更新日期：2010-10-01 00:00:00

abstract：:The dynamic regulation of integrin-binding peptides is crucial for chondrogenic differentiation. Here, we revealed the feasibility for flexible modification of RGD by embedding a large molecular weight and slightly charged (isoelectric point, 6-6.25) RGD-chimeric protein (CBD-RGD) with cellulose-binding domain (CBD) i...

journal_title：Biomaterials

authors： Chang JC,Hsu SH,Chen DC

更新日期：2009-10-01 00:00:00

abstract：:CD47, a "don't eat me" signal, is over-expressed on the surface of most tumors that interacts with signal regulatory protein α (SIRPα) on phagocytic cells. By engaging SIRPα, CD47 limits the ability of macrophages to engulf tumor cells, which acts as a major phagocytic barrier. In this study, we developed an exosome-b...

journal_title：Biomaterials

authors： Koh E,Lee EJ,Nam GH,Hong Y,Cho E,Yang Y,Kim IS

更新日期：2017-03-01 00:00:00

abstract：:It is well known that biomaterials play an important role in the regulation of adhesion and growth of a variety of cultured cell types. However, whether biomaterials are associated with the senescence of cultured cells is not known. The present work shows that the decrease of the hydrophobic property of poly (ethylene...

journal_title：Biomaterials

authors： Lou PJ,Chiu MY,Chou CC,Liao BW,Young TH

更新日期：2010-03-01 00:00:00

abstract：:A PCL/hydrogel construct that would mimic the structural organization, biochemistry and anatomy of meniscus was engineered. The compressive (380 ± 40 kPa) and tensile modulus (18.2 ± 0.9 MPa) of the PCL scaffolds were increased significantly when constructs were printed with a shifted design and circumferential strand...

journal_title：Biomaterials

authors： Bahcecioglu G,Bilgen B,Hasirci N,Hasirci V

更新日期：2019-10-01 00:00:00

abstract：:The synthesis of poly(lactic acid) through polycondensation of the lactic acid monomer gave weight average molecular weights (Mw) lower than 1.6 x 10(4), whereas ring-opening polymerization of lactides in bulk at 130 degrees C for 72 h using stannous octoate as catalyst in the concentration range from 0.003 to 0.8 wt%...

journal_title：Biomaterials

authors： Hyon SH,Jamshidi K,Ikada Y

更新日期：1997-11-01 00:00:00

abstract：:Bioceramic coatings, created by the high velocity oxy-fuel combustion spraying of hydroxyapatite (HA) powders onto commercially pure titanium, were characterized in order to determine whether this relatively new coating process can be successfully applied to bioceramic coatings of orthopaedic and dental implants. Four...

journal_title：Biomaterials

authors： Haman JD,Lucas LC,Crawmer D

更新日期：1995-02-01 00:00:00

abstract：:Experimental and histological studies on the reaction of surrounding gingiva to permucosal implants of dense calcium hydroxyapatite were carried out in dogs. Epithelial attachment and connection of supra-alveolar collagen fibres to the implant surface seemed to form a biological seal around implants similar to that ar...

journal_title：Biomaterials

authors： Kurashina K,de Lange GL,de Putter C,de Groot K

更新日期：1984-07-01 00:00:00

abstract：:The present study deals with the synthesis and characterization of radiopaque polymers which could, when solubilized in an appropriate water-miscible solvent, be useful embolic materials for the treatment of cerebral aneurysms and arteriovenous malformations. For this purpose cellulose (both microcrystalline and powde...

journal_title：Biomaterials

authors： Mottu F,Rüfenacht DA,Laurent A,Doelker E

更新日期：2002-01-01 00:00:00

abstract：:Sol-gel derived porous silica carriers for the controlled release of proteins were synthesized using a room temperature process. The materials are intended to serve as both substrates for bone growth as well as to allow incorporated proteins such as growth factors to diffuse out and stimulate cell function and tissue ...

journal_title：Biomaterials

authors： Santos EM,Radin S,Ducheyne P

更新日期：1999-09-01 00:00:00

abstract：:Gelatin and dextran were blended and crosslinked to form enzymatically degradable interpenetrating polymeric networks (IPNs) as materials for degradable implants. Several crosslinking methods were investigated including treatment with glyceraldehyde, thermal hardening, and chelation of dextran by divalent metal cation...

journal_title：Biomaterials

authors： Kosmala JD,Henthorn DB,Brannon-Peppas L

更新日期：2000-10-01 00:00:00

abstract：:A procedure for preparing homogeneous chitosan gels by in situ molybdate cross-linking is described. The gels are obtained by dispersing solid MoO3 in a buffered chitosan solution and the polymer is cross-linked by formation of heavily negatively charged molybdate polyoxyanions. The resulting ionic gels are very trans...

journal_title：Biomaterials

authors： Draget KI,Vårum KM,Moen E,Gynnild H,Smidsrød O

更新日期：1992-01-01 00:00:00

abstract：:The objective of this research was to investigate whether immobilized anti-inflammatory cytokines will signal changes in the inflammatory profile of cultured monocytes. A fusion protein of recombinant human IL-1 receptor antagonist and elastin-like peptide (IL-1ra-ELP) was expressed in Escherichia coli. THP-1 human mo...

journal_title：Biomaterials

authors： Kim DH,Smith JT,Chilkoti A,Reichert WM

更新日期：2007-08-01 00:00:00

abstract：:Three proprietary dental resins were found to include acrylates (as distinct from methacrylates). As acrylates are well known to have adverse skin reactions, the nature and content of the acrylates were obtained. One resin contained methyl acrylate, and the other two ethyl acrylate. Also, the extractable free monomer ...

journal_title：Biomaterials

authors： Davy KW,Braden M

更新日期：1991-08-01 00:00:00

abstract：:Intervertebral disc (IVD) herniation causes pain and disability, but current discectomy procedures alleviate pain without repairing annulus fibrosus (AF) defects. Tissue engineering strategies seal AF defects by utilizing hydrogel systems to prevent recurrent herniation, however current biomaterials are limited by poo...

journal_title：Biomaterials

authors： DiStefano TJ,Shmukler JO,Danias G,Di Pauli von Treuheim T,Hom WW,Goldberg DA,Laudier DM,Nasser PR,Hecht AC,Nicoll SB,Iatridis JC

更新日期：2020-11-01 00:00:00

abstract：:The ability to influence the direction of polymerization of a self-assembling biomolecular system has the potential to generate materials with extremely high anisotropy. In biological systems where highly-oriented cellular populations give rise to aligned and often load-bearing tissue such organized molecular scaffold...

journal_title：Biomaterials

authors： Saeidi N,Sander EA,Ruberti JW

更新日期：2009-12-01 00:00:00

abstract：:Ultrasound imaging is a widely used imaging technique. The use of contrast agents has become an indispensible part of clinical ultrasound imaging, and molecular imaging via ultrasound has recently attracted significant attention. We recently reported that "Bubble liposomes" (BLs) encapsulating US imaging gas liposomes...

journal_title：Biomaterials

authors： Negishi Y,Hamano N,Tsunoda Y,Oda Y,Choijamts B,Endo-Takahashi Y,Omata D,Suzuki R,Maruyama K,Nomizu M,Emoto M,Aramaki Y

更新日期：2013-01-01 00:00:00

abstract：:The purpose of this study was to investigate the chemical influence of chemo-mechanical caries removal (CMCR) on surface topography of dental ceramic materials. Thirty samples of three different types of ceramics (Vita Omega, Vita Alpha, and Procera AllTitan) were manufactured and used. With an optical profilometer, d...

journal_title：Biomaterials

authors： Arvidsson A,Milleding P,Wennerberg A

更新日期：2002-10-01 00:00:00

abstract：:Premature ovarian failure (POF) is the most frequently occurred disease in ovary. Direct inhibition of mammalian target of rapamycin (mTOR) activity can treat woman POF but brings adverse effects to women. Herein, by rational design of a hydrogelator Nap-Phe-Phe-Asp-Arg-Leu-Tyr-OH (Y) and co-assembling Y with an inhib...

journal_title：Biomaterials

authors： Shi Z,Li X,Wei M,Chen P,Zhang T,Ling X,Zhang J,Zhao C,Wang F,Liang G

更新日期：2020-11-16 00:00:00

abstract：:Tubular vessels for tissue engineering are typically fabricated using a molding, dipping, or electrospinning technique. While these techniques provide some control over inner and outer diameters of the tube, they lack the ability to align the polymers or fibers of interest throughout the tube. This is an important asp...

journal_title：Biomaterials

authors： Lovett ML,Cannizzaro CM,Vunjak-Novakovic G,Kaplan DL

更新日期：2008-12-01 00:00:00

abstract：:Surface microroughness increases osteoblast differentiation and enhances responses of osteoblasts to 1,25-dihydroxyvitamin D3 [1alpha,25(OH)2D3]. The observations that beta1 integrin expression is increased in osteoblasts grown on Ti substrates with rough microarchitecture, and that it is regulated by 1alpha,25(OH)2D3...

journal_title：Biomaterials

authors： Wang L,Zhao G,Olivares-Navarrete R,Bell BF,Wieland M,Cochran DL,Schwartz Z,Boyan BD

更新日期：2006-07-01 00:00:00

abstract：:The necessity of information about the inner microscopical features of low absorbing materials is one of the most important goals in the structural research field. So far, non destructive analysis have been performed using contact radiography giving the scope for great advances in the production and application of new...

journal_title：Biomaterials

authors： Baruchel J,Lodini A,Romanzetti S,Rustichelli F,Scrivani A

更新日期：2001-06-01 00:00:00

abstract：:Bone defects caused by fractures or cancer-mediated destruction are debilitating. Chitosan is commonly used in scaffold matrices for bone healing, but rarely as a free drug. We demonstrate that free chitosan promotes osteoblast proliferation and osteogenesis in mesenchymal stem cells, increases osteopontin and collage...

journal_title：Biomaterials

authors： Tan ML,Shao P,Friedhuber AM,van Moorst M,Elahy M,Indumathy S,Dunstan DE,Wei Y,Dass CR

更新日期：2014-09-01 00:00:00

abstract：:The physiological activity of hyaluronic acid (HA) polymers and oligomers makes it a promising material for a variety of applications. The development of HA-hydrogel scaffolds with improved mechanical stability against degradation and biochemical functionality may enhance their application to tissue engineering. In th...

journal_title：Biomaterials

authors： Segura T,Anderson BC,Chung PH,Webber RE,Shull KR,Shea LD

更新日期：2005-02-01 00:00:00

abstract：:The design of peptide-based subunit vaccine formulations for the direct delivery of tumor antigen peptides (Aps) to dendritic cells (DCs) localized within draining lymph nodes (DLNs) is challenging. Mature DCs (mDCs) are abundantly distributed within DLNs but have dramatically reduced endocytic uptake and antigen-proc...

journal_title：Biomaterials

authors： Qian Y,Jin H,Qiao S,Dai Y,Huang C,Lu L,Luo Q,Zhang Z

更新日期：2016-08-01 00:00:00

abstract：:In this work, the in vitro interaction of cerebellar granule neurons prepared from 7-day-old Wistar rats and poly ethylene-co-vinyl alcohol (EVAL) membranes was investigated. Cells were cultured in smooth and particulate EVAL membranes for up to 7 days. Particulate membranes were prepared by using 1-octanol to precipi...

journal_title：Biomaterials

authors： Young TH,Lin CW,Cheng LP,Hsieh CC

更新日期：2001-07-01 00:00:00

abstract：:Superparamagnetic magnetite nanoparticles (MNP) coated with silica were synthesized and chronically implanted into the middle ear epithelial tissues of a guinea pig model (n=16) for the generation of force by an external magnetic field. In vivo limitations of biocompatibility include particle morphology, size distribu...

journal_title：Biomaterials

authors： Dormer K,Seeney C,Lewelling K,Lian G,Gibson D,Johnson M

更新日期：2005-05-01 00:00:00

abstract：:The efficient generation of integration- and xeno-free iPSCs is a prerequisite for their use in clinical applications. Furthermore, non-invasiveness of somatic cell acquisition for iPSC generation is another factor to consider. In this study, we established a practical, simple, and convenient method to generate integr...

journal_title：Biomaterials

authors： Lee KI,Kim HT,Hwang DY

更新日期：2014-09-01 00:00:00

abstract：:Islet transplantation is a method for the treatment of type 1 diabetes mellitus (DM) and has been widely performed around the world. The long-term cryopreservation of islets shows many advantages in the field of islet transplantation. Previous studies have described the development of sheet-type polyvinyl alcohol (PVA...

journal_title：Biomaterials

authors： Qi Z,Shen Y,Yanai G,Yang K,Shirouzu Y,Hiura A,Sumi S

更新日期：2010-05-01 00:00:00