Particle shape dependence of CD8+ T cell activation by artificial antigen presenting cells.

abstract：:Replacing the tissue lost after a stroke potentially provides a new neural substrate to promote recovery. However, significant neurobiological and biotechnological challenges need to be overcome to make this possibility into a reality. Human neural stem cells (hNSCs) can differentiate into mature brain cells, but requ...

journal_title：Biomaterials

authors： Bible E,Qutachi O,Chau DY,Alexander MR,Shakesheff KM,Modo M

更新日期：2012-10-01 00:00:00

abstract：:To understand the effect of photosensitizer (PS) release from graft copolymer based micelles in photodynamic therapy (PDT), the two pH-sensitive and non-pH-sensitive graft copolymers, (poly(N-vinyly caprolactam)-g-poly(D,L-lactide) and poly(N-vinyly caprolactam-co-N-vinyl imidazole)-g-poly(D,L-lactide)), were synthesi...

journal_title：Biomaterials

authors： Tsai HC,Tsai CH,Lin SY,Jhang CR,Chiang YS,Hsiue GH

更新日期：2012-02-01 00:00:00

abstract：:In vivo and in vitro degradation of high molecular weight poly(L-lactide) used for internal bone fixation has been investigated. Within 3 months as-polymerized, microporous PLLA (Mv = 6.8-9.5 X 10(5] exhibited a massive strength-loss (sigma b = 68-75 MPa to sigma b = 4 MPa) and decrease of Mv (90-95%). At week 39, the...

journal_title：Biomaterials

authors： Leenslag JW,Pennings AJ,Bos RR,Rozema FR,Boering G

更新日期：1987-07-01 00:00:00

abstract：:Sintered bovine cancellous bone exhibited excellent biocompatiblity, high porosity and have an interconnecting porous structure allowing for bone ingrowth. However, the main mineral constitution of sintered bovine bone-hydroxyapatite (Ca10(PO4)6(OH)2, HAP) seems to be too stable in vivo. For improving its bioactivity,...

journal_title：Biomaterials

authors： Lin FH,Liao CJ,Chen KS,Sun JS

更新日期：1999-03-01 00:00:00

abstract：:The design of new bioactive scaffolds mimicking the physiologic environment present during tissue formation is an important frontier in biomaterials research. Herein, we evaluated scaffolds prepared from blends of two biopolymers: silk fibroin and hyaluronan. Our rationale was that such blends would allow the combinat...

journal_title：Biomaterials

authors： Garcia-Fuentes M,Meinel AJ,Hilbe M,Meinel L,Merkle HP

更新日期：2009-10-01 00:00:00

abstract：:The interaction of three cell types important to the wound repair process with collagen/glycosaminoglycan (GAG) dermal regeneration matrices covalently modified with an Arg-Gly-Asp (RGD)-containing peptide was characterized. Function-blocking monoclonal antibodies directed against various integrin subunits were used t...

journal_title：Biomaterials

authors： Grzesiak JJ,Pierschbacher MD,Amodeo MF,Malaney TI,Glass JR

更新日期：1997-12-01 00:00:00

abstract：:In the present study, we tested the hypothesis that electroporation-mediated transfer of Runx2, Osterix, or both genes enhances the in vitro and in vivo osteogenesis from adipose stem cells (ASCs). ASCs were transfected with Runx2, Osterix, or both genes using electroporation, and further cultured in monolayer or in P...

journal_title：Biomaterials

authors： Lee JS,Lee JM,Im GI

更新日期：2011-01-01 00:00:00

abstract：:There is a great clinical need for tissue engineered blood vessels that could be used to replace or bypass damaged arteries. The success of such grafts will depend strongly on their ability to mimic the cellular and matrix organization found in native arteries, but currently available cell scaffolds such as electrospu...

journal_title：Biomaterials

authors： McClendon MT,Stupp SI

更新日期：2012-08-01 00:00:00

abstract：:Certain types of implanted medical devices depend on oxygen supplied from surrounding tissues for their function. However, there is a concern that the tissue associated with the foreign body response to implants may become impermeable to oxygen over the long term and render the implant nonfunctional. We report oxygen ...

journal_title：Biomaterials

authors： Kumosa LS,Routh TL,Lin JT,Lucisano JY,Gough DA

更新日期：2014-09-01 00:00:00

abstract：:The aim of this study, in rabbit tibia, was an evaluation of the early reactions of the tissues to the insertion of polylactic membranes, used in connection with titanium implants. The specimens were retrieved after 1-4 weeks, and a histological analysis was performed. It was possible to see that, in the early implant...

journal_title：Biomaterials

authors： Piattelli A,Scarano A,Coraggio F,Matarasso S

更新日期：1998-05-01 00:00:00

abstract：:Phototherapy has drawn increasing attention including the use of nanocarriers with high drug loading capacity and delivery efficacy for target-specific therapy. We have made use of naturally-occurring halloysite nanotubes (HNTs) to build a biomimetic nanocarrier platform for target-specific delivery of phototherapeuti...

journal_title：Biomaterials

authors： Li LY,Zhou YM,Gao RY,Liu XC,Du HH,Zhang JL,Ai XC,Zhang JP,Fu LM,Skibsted LH

更新日期：2019-01-01 00:00:00

abstract：:We compared the osteogenic response in porous alumni (Al) and hydroxyapatite coated porous alumni ceramic (HA/Al) by grafting rat bone marrow cells with these implants subcutaneously in the back of syngeneic rats. The ceramics did not show any bone formation without marrow, but did when combined with marrow cells. The...

journal_title：Biomaterials

authors： Takaoka T,Okumura M,Ohgushi H,Inoue K,Takakura Y,Tamai S

更新日期：1996-08-01 00:00:00

abstract：:A glucose biosensor was fabricated with loading of glucose oxidase (GOx) into a new organic-inorganic hybrid nanocomposite. The preparation involves formation of silica network into a Nafion (perfluorosulfonate ionomer) and subsequent loading of polyaniline grafted multiwalled carbon nanotubes (MWNT-g-PANI) onto Nafio...

journal_title：Biomaterials

authors： Gopalan AI,Lee KP,Ragupathy D,Lee SH,Lee JW

更新日期：2009-10-01 00:00:00

abstract：:Three proprietary dental resins were found to include acrylates (as distinct from methacrylates). As acrylates are well known to have adverse skin reactions, the nature and content of the acrylates were obtained. One resin contained methyl acrylate, and the other two ethyl acrylate. Also, the extractable free monomer ...

journal_title：Biomaterials

authors： Davy KW,Braden M

更新日期：1991-08-01 00:00:00

abstract：:The purpose of this study was to determine the mechanical properties and the atomistic structures of various gelatin hydrogels as a preliminary to using these in bioengineering applications. The hydrogels were investigated as neat materials and as particulate-reinforced composites both in the as-formed state and follo...

journal_title：Biomaterials

authors： Usta M,Piech DL,MacCrone RK,Hillig WB

更新日期：2003-01-01 00:00:00

abstract：:Over the past two decades, in vitro autologous endothelial cell (EC) coverage of expanded polytetrafluoroethylene (ePTFE) graft has been developed and clinically applied with success in infrainguinal bypasses. Before endothelialization, the luminal surface of the graft has to be coated with a currently used fibrinolyt...

journal_title：Biomaterials

authors： Fernandez P,Deguette A,Pothuaud L,Belleannée G,Coste P,Bordenave L

更新日期：2005-08-01 00:00:00

abstract：:Poor fixation of bone replacement implants, e.g. the artificial hip, in implantation sites with inferior bone quality and quantity may be overcome by the use of implants coated with a cultured living bone equivalent. In this study, we tested, respectively, amorphous carbonated apatite (CA)- and crystalline octacalcium...

journal_title：Biomaterials

authors： Dekker RJ,de Bruijn JD,Stigter M,Barrere F,Layrolle P,van Blitterswijk CA

更新日期：2005-09-01 00:00:00

abstract：:Anchorage-dependent cells (NRK 49F) were grown at 37 degrees C in serum containing medium on glass coated with a N-isopropyl acrylamide/N-t-butyl acrylamide copolymer (NIPAaM/NTBAM) with a lower critical solution temperature (LCST) of 8 degrees C. After incubating the dishes and adherent cells at 4 degrees C for 1 h, ...

journal_title：Biomaterials

authors： Rollason G,Davies JE,Sefton MV

更新日期：1993-01-01 00:00:00

abstract：:Chitosans with various degrees of deacetylation were synthesized by acetylation with acetic anhydride. These chitosans were evaluated for efficacy of nanoparticle formation, DNA binding efficiency, morphology, and in vitro and in vivo gene transfection efficiency. DNA binding efficacy was reduced as degree of deacetyl...

journal_title：Biomaterials

authors： Kiang T,Wen J,Lim HW,Leong KW

更新日期：2004-10-01 00:00:00

abstract：:Titanium surfaces with micro-nano hybrid topography (nanoscale nodules in microscale pits) have been recently demonstrated to show higher biological capability than those with microtopography alone. On the other hand, UV treatment of titanium surfaces, which is called UV photofunctionalization, has recently been intro...

journal_title：Biomaterials

authors： Tsukimura N,Yamada M,Iwasa F,Minamikawa H,Att W,Ueno T,Saruwatari L,Aita H,Chiou WA,Ogawa T

更新日期：2011-07-01 00:00:00

abstract：:Engineered nanomaterials are known to exhibit diverse and sometimes unexpected biological effects. Fullerene nanoparticles have been reported to specifically bind to and elicit persistent activation of hippocampal Ca(2+)/calmodulin-dependent protein kinase II (CaMKII), a multimeric intracellular serine/threonine kinas...

journal_title：Biomaterials

authors： Chen L,Miao Y,Chen L,Xu J,Wang X,Zhao H,Shen Y,Hu Y,Bian Y,Shen Y,Chen J,Zha Y,Wen LP,Wang M

更新日期：2014-11-01 00:00:00

abstract：:The early biological response at titanium (Ti), copper (Cu)-coated Ti and sham sites was evaluated in an in vivo rat model. Material surface chemical and topographical properties were characterized using Auger electron spectroscopy, energy dispersive X-ray spectroscopy and interferometry, respectively. The number of l...

journal_title：Biomaterials

authors： Suska F,Gretzer C,Esposito M,Emanuelsson L,Wennerberg A,Tengvall P,Thomsen P

更新日期：2005-02-01 00:00:00

abstract：:Vascular smooth muscle cells (VSMCs) isolated from rabbit aorta and immortalised A7r5 cells were cultured on conducting polypyrrole (PPy) substrates and were subjected to a 50muA sinusoidal electrical stimulation at 0.05, 5 and 500 Hz. These substrates were doped with hyaluronic acid and coated with collagen IV follow...

journal_title：Biomaterials

authors： Rowlands AS,Cooper-White JJ

更新日期：2008-12-01 00:00:00

abstract：:Bone is the most frequent metastasis site for breast cancer. As well as dramatically increasing disease burden, bone metastases are also an indicator of poor prognosis. One of the main challenges in investigating bone metastasis in breast cancer is engineering in vitro models that replicate the features of in vivo bon...

journal_title：Biomaterials

authors： Han W,El Botty R,Montaudon E,Malaquin L,Deschaseaux F,Espagnolle N,Marangoni E,Cottu P,Zalcman G,Parrini MC,Assayag F,Sensebe L,Silberzan P,Vincent-Salomon A,Dutertre G,Roman-Roman S,Descroix S,Camonis J

更新日期：2020-12-24 00:00:00

abstract：:Dacron velour is often used to anchor a percutaneous device, like the catheter used in peritoneal dialysis. However, exit-site infections complicate this method of dialysis and are supposed to be related to the design of the catheter. In animal experiments, a percutaneous device provided with a titanium fibre mesh to ...

journal_title：Biomaterials

authors： Paquay YC,de Ruijter JE,van der Waerden JP,Jansen JA

更新日期：1996-06-01 00:00:00

abstract：:The histology and cytology of the tissue response to intra-articular insertion of particles of acrylic bone cement containing barium sulphate has been studied in the guinea pig knee joint. Following insertion of the acrylic, fibrinous debris admixed with particles became adherent to the synovial membrane. Cell prolife...

journal_title：Biomaterials

authors： Meachim G,Brooke G

更新日期：1984-03-01 00:00:00

abstract：:Human induced pluripotent stem cell (hiPSC) derived angiogenesis models present a unique opportunity for patient-specific platforms to study the complex process of angiogenesis and the endothelial cell response to biomaterial and biophysical changes in a defined microenvironment. We present a refined method for differ...

journal_title：Biomaterials

authors： Natividad-Diaz SL,Browne S,Jha AK,Ma Z,Hossainy S,Kurokawa YK,George SC,Healy KE

更新日期：2019-02-01 00:00:00

abstract：:Restoration of tissue integrity and tissue function of wounded skin are both essential for wound repair and regeneration, while synergistic promotion of the two remains elusive. Since elevated reactive oxygen species (ROS) production in the injured site has been implicated in triggering a set of deleterious effects su...

journal_title：Biomaterials

authors： Wu H,Li F,Wang S,Lu J,Li J,Du Y,Sun X,Chen X,Gao J,Ling D

更新日期：2018-01-01 00:00:00

abstract：:A nanohybrid vesicle was developed from cholesteryl succinyl silane(CSS) in combination of sol-gel process and self-assembly technique. The silicalike surface adds CSS vesicles remarkably high stability against destabilization in blood or leakage of drug cargos. It was found that CSS vesicles alone exhibited selective...

journal_title：Biomaterials

authors： Ma Y,Dai Z,Zha Z,Gao Y,Yue X

更新日期：2011-12-01 00:00:00

abstract：:Peripheral nerve injuries often lead to incomplete recovery and contribute to significant disability to approximately 360,000 people in the USA each year. Stem cell therapy holds significant promise for peripheral nerve regeneration, but maintenance of stem cell viability and differentiation potential in vivo are stil...

journal_title：Biomaterials

authors： Du J,Zhen G,Chen H,Zhang S,Qing L,Yang X,Lee G,Mao HQ,Jia X

更新日期：2018-10-01 00:00:00