The synovial response to intra-articular acrylic cement particles in guinea pigs.

abstract：:The introduction of vaccines is regarded as one of the most successful medical interventions to date. However, there is a clear need for the development of new vaccines for diseases which require the induction of a potent cellular immune response. Advancements in the field of vaccine research have resulted in a move a...

journal_title：Biomaterials

authors： Moran HBT,Turley JL,Andersson M,Lavelle EC

更新日期：2018-11-01 00:00:00

abstract：:Heparin-conjugated electrospun poly(ε-caprolactone) (PCL)/gelatin scaffolds were developed to provide controlled release of platelet-derived growth factor-BB (PDGF-BB) and allow prolonged bioactivity of this molecule. A mixture of PCL and gelatin was electrospun into three different morphologies. Next, heparin molecul...

journal_title：Biomaterials

authors： Lee J,Yoo JJ,Atala A,Lee SJ

更新日期：2012-10-01 00:00:00

abstract：:Intercellular interactions in the cell microenvironment play a critical role in determining cell fate, but the effects of these interactions on pathways governing human embryonic stem cell (hESC) behavior have not been fully elucidated. We and others have previously reported that 3-D culture of hESCs affects cell fate...

journal_title：Biomaterials

authors： Azarin SM,Lian X,Larson EA,Popelka HM,de Pablo JJ,Palecek SP

更新日期：2012-03-01 00:00:00

abstract：:Biomedical alloys may release nickel ions during corrosion phenomena and, in addition to their interaction with oral tissues, these ions may also influence characteristic properties of the immune system cells. The aim of this study was to evaluate the effect of nickel chloride on the expression of functionally distinc...

journal_title：Biomaterials

authors： D'Antò V,Eckhardt A,Hiller KA,Spagnuolo G,Valletta R,Ambrosio L,Schmalz G,Schweikl H

更新日期：2009-03-01 00:00:00

abstract：:Wound dressing is critical important for cutaneous wound healing. However, the application of current products is limited due to poor mechanical property, unsuitable water vapor transmission rate (WVTR), poor anti-infective property or poor biocompatibility, etc. In the present study, a microporous silicone rubber mem...

journal_title：Biomaterials

authors： Xu R,Luo G,Xia H,He W,Zhao J,Liu B,Tan J,Zhou J,Liu D,Wang Y,Yao Z,Zhan R,Yang S,Wu J

更新日期：2015-02-01 00:00:00

abstract：:To explore molecular mechanism of mediation of adsorbed proteins to cell adhesion and growth on biomaterials, this study examined endothelial cell adhesion, morphology and viability on bare and titanium nitride (TiN) coated nickel titanium (NiTi) alloys and chitosan film firstly, and then identified the type and amoun...

journal_title：Biomaterials

authors： Yang D,Lü X,Hong Y,Xi T,Zhang D

更新日期：2013-07-01 00:00:00

abstract：:The aim of this study was to characterize a nasally delivered bioadhesive liposome using an inactivated H5N3 virus as a model antigen. Bioadhesive liposomes were developed using tremella (T) or xanthan gum (XG) as the bioadhesive polysaccharide. Using chickens as the target animal, we evaluated whether delivery of a b...

journal_title：Biomaterials

authors： Chiou CJ,Tseng LP,Deng MC,Jiang PR,Tasi SL,Chung TW,Huang YY,Liu DZ

更新日期：2009-10-01 00:00:00

abstract：:Brain tumors and brain metastases are among the deadliest malignancies of all human cancers, largely due to the cellular blood-brain and blood-tumor barriers that limit the delivery of imaging and therapeutic agents from the systemic circulation to tumors. Thus, improved strategies for brain tumor visualization and ta...

journal_title：Biomaterials

authors： Wu JB,Shi C,Chu GC,Xu Q,Zhang Y,Li Q,Yu JS,Zhau HE,Chung LW

更新日期：2015-10-01 00:00:00

abstract：:Combined and targeted therapy have been extensively employed to achieve more effective elimination of tumor tissues. In this study, biocompatible multifunctional lipid-coated calcium phosphate nanoparticles (LCP NPs) were designed and constructed as an efficient targeted delivery system for combined gene/photothermal ...

journal_title：Biomaterials

authors： Tang J,Li B,Howard CB,Mahler SM,Thurecht KJ,Wu Y,Huang L,Xu ZP

更新日期：2019-09-01 00:00:00

abstract：:Hydrogels provide three-dimensional frameworks with tissue-like elasticity and high permeability for culturing therapeutically relevant cells or tissues. While recent research efforts have created diverse macromer chemistry to form hydrogels, the mechanisms of hydrogel polymerization for in situ cell encapsulation rem...

journal_title：Biomaterials

authors： Lin CC,Raza A,Shih H

更新日期：2011-12-01 00:00:00

abstract：:Peel bond strength and tensile bond strength between three polyvinylsiloxane denture soft liners and a heat-cured acrylic resin denture base were measured using two adhesive systems. The soft lining materials differed only in regard of their filler content and compliance. The values of bond strength and mode of failur...

journal_title：Biomaterials

authors： McCabe JF,Carrick TE,Kamohara H

更新日期：2002-03-01 00:00:00

abstract：:Cell-extracellular cell matrix (ECM) interactions play a vital role in development including cytoskeletal structure, growth and differentiation. A 15 amino acid, non-RGD containing, peptide that is derived from type I collagen was tested for its ability to confer cell survival. Two routinely utilized bone graft materi...

journal_title：Biomaterials

authors： Hanks T,Atkinson BL

更新日期：2004-08-01 00:00:00

abstract：:Bone tissue engineering strategies are fundamentally based upon porous scaffold materials that serve as a support for ingrowth of host cells and/or provide a substrate for exogenously delivered cells. Here we report the application of a surface calcium phosphate (CaP) mineral layer to a macroporous polymeric/CaP compo...

journal_title：Biomaterials

authors： Lickorish D,Guan L,Davies JE

更新日期：2007-03-01 00:00:00

abstract：:We have developed nanoparticles based on Murine Leukemia Virus virus-like-particles (VLPs) that efficiently deliver therapeutic bioactive proteins in their native state into target cells. Nuclear transcription factors and toxic proteins were incorporated into the VLPs from stable producer cells without transducing vir...

journal_title：Biomaterials

authors： Wu DT,Roth MJ

更新日期：2014-09-01 00:00:00

abstract：:RNA interference induced by double-stranded, small interfering RNA (siRNA) molecules has attracted great attention as a genetic therapeutic approach. Despite major advances in this field, new nanoparticle formulations are required for in vivo delivery of siRNA, particularly for tissue-specific delivery of siRNA reagen...

journal_title：Biomaterials

authors： Tagalakis AD,He L,Saraiva L,Gustafsson KT,Hart SL

更新日期：2011-09-01 00:00:00

abstract：:The physiological role of cumulus cell surrounding oocytes is particularly important for normal cytoplasmic maturation of oocytes. Collagen-based demineralized bone matrix (DBM) is a valuable biomaterial for the three-dimensional (3-D) cell culture. The present study was designed to determine whether in vitro maturati...

journal_title：Biomaterials

authors： Ma S,Lin H,Miao Y,Liu X,Wang B,Dai J

更新日期：2007-07-01 00:00:00

abstract：:An oxygen-permeable membrane bioreactor utilizing human hepatocytes has been tested in this study. In the bioreactor, human hepatocytes were cultured between flat-sheet gas-permeable polymeric membranes, which ensure the diffusion of O(2) and CO(2) providing a support for cell anchorage and growth and permit the onlin...

journal_title：Biomaterials

authors： De Bartolo L,Salerno S,Morelli S,Giorno L,Rende M,Memoli B,Procino A,Andreucci VE,Bader A,Drioli E

更新日期：2006-09-01 00:00:00

abstract：:The use of bone cement to treat vertebral compression fractures in a percutaneous manner requires placement of the cement under fluoroscopic image guidance. To enhance visualization of the flow during injection and to monitor and prevent leakage beyond the confines of the vertebral body, the orthopedic community has d...

journal_title：Biomaterials

authors： Kurtz SM,Villarraga ML,Zhao K,Edidin AA

更新日期：2005-06-01 00:00:00

abstract：:Endocytosis is a fundamental biological process and is also the key mechanism for drug and non-viral gene delivery. The importance of topographical cues in modulating cell behaviors has become increasingly evident, but the influence of topography on endocytosis has however only been sparsely studied. We hypothesize th...

journal_title：Biomaterials

authors： Teo BK,Goh SH,Kustandi TS,Loh WW,Low HY,Yim EK

更新日期：2011-12-01 00:00:00

abstract：:Bone is the most frequent metastasis site for breast cancer. As well as dramatically increasing disease burden, bone metastases are also an indicator of poor prognosis. One of the main challenges in investigating bone metastasis in breast cancer is engineering in vitro models that replicate the features of in vivo bon...

journal_title：Biomaterials

authors： Han W,El Botty R,Montaudon E,Malaquin L,Deschaseaux F,Espagnolle N,Marangoni E,Cottu P,Zalcman G,Parrini MC,Assayag F,Sensebe L,Silberzan P,Vincent-Salomon A,Dutertre G,Roman-Roman S,Descroix S,Camonis J

更新日期：2020-12-24 00:00:00

abstract：:We report the synthesis and characterization of dendrimer-entrapped gold nanoparticles (Au DENPs) modified by polyethylene glycol (PEG) with enhanced biocompatibility for computed tomography (CT) imaging applications. In this study, amine-terminated poly(amidoamine) dendrimers of generation 5 (G5.NH(2)) modified by PE...

journal_title：Biomaterials

authors： Peng C,Zheng L,Chen Q,Shen M,Guo R,Wang H,Cao X,Zhang G,Shi X

更新日期：2012-02-01 00:00:00

abstract：:Prosthetic heart valves epitomize both the triumphant advance of cardiac surgery in its early days and its stagnation into a retrospective, exclusive first world discipline of late. Fifty-two years after the first diseased heart valve was replaced in a patient, prostheses largely represent the concepts of the 1960s wi...

journal_title：Biomaterials

authors： Zilla P,Brink J,Human P,Bezuidenhout D

更新日期：2008-02-01 00:00:00

abstract：:Films of polyoxyethylene network were prepared from two types of triethoxysilane-terminated prepolymers. In this way, films of polyoxyethylene network with possible applications in the biomedical field could be made easier. To test their biocompatibility, these networks were added to organ cultures of adult human skin...

journal_title：Biomaterials

authors： Beele H,Thierens H,Deveux R,Goethals E,de Ridder L

更新日期：1992-01-01 00:00:00

abstract：:We investigated the hypothesis that immobilizing TGF-β1 within fibrin hydrogels may act in synergy with cyclic mechanical stimulation to enhance the properties of vascular grafts. To this end, we engineered a fusion TGF-β1 protein that can covalently anchor to fibrin during polymerization upon the action of factor XII...

journal_title：Biomaterials

authors： Liang MS,Koobatian M,Lei P,Swartz DD,Andreadis ST

更新日期：2013-10-01 00:00:00

abstract：:The interaction of three cell types important to the wound repair process with collagen/glycosaminoglycan (GAG) dermal regeneration matrices covalently modified with an Arg-Gly-Asp (RGD)-containing peptide was characterized. Function-blocking monoclonal antibodies directed against various integrin subunits were used t...

journal_title：Biomaterials

authors： Grzesiak JJ,Pierschbacher MD,Amodeo MF,Malaney TI,Glass JR

更新日期：1997-12-01 00:00:00

abstract：:In order to clarify the role of a primer on the adhesion between dental precious metals and resin, surface-enhanced Raman scattering (SERS) technique has been applied to the structural analysis of the adhesive monomer, 6-(N-(4-vinylbenzyl)propylamino)-1,3,5-triazine-2, 4-dithione (VBATDT) adsorbed on colloidal Au surf...

journal_title：Biomaterials

authors： Suzuki M,Fujishima A,Miyazaki T,Hisamitsu H,Kojima K,Kadoma Y

更新日期：1999-05-01 00:00:00

abstract：:This study was conducted to determine the interaction of individual corrosion products from biodegradable iron stents with cells from the adjacent tissue. The response of human umbilical venous smooth muscle cells (SMCs) to an excess of ferrous ions was investigated in a cell culture model at the phenotypic and at the...

journal_title：Biomaterials

authors： Mueller PP,May T,Perz A,Hauser H,Peuster M

更新日期：2006-04-01 00:00:00

abstract：:Poly(N-isopropylacrylamide) (PNIPAAm) is known to be thermally responsive material and has a lower critical solution temperature (LCST, 32 degrees C) at which a macromolecular transition from a hydrophilic to a hydrophobic structure occurs. Chitosan is a useful natural polymeric biomaterial due to its biocompatibility...

journal_title：Biomaterials

authors： Cho JH,Kim SH,Park KD,Jung MC,Yang WI,Han SW,Noh JY,Lee JW

更新日期：2004-11-01 00:00:00

abstract：:Human adipose tissue extracellular matrix, derived through decellularization processing, has been shown to provide a biomimetic microenvironment for adipose tissue regeneration. This study reports the use of human adipose tissue-derived extracellular matrix (hDAM) scaffolds as a three-dimensional cell culturing system...

journal_title：Biomaterials

authors： Dunne LW,Huang Z,Meng W,Fan X,Zhang N,Zhang Q,An Z

更新日期：2014-06-01 00:00:00

abstract：:New crosslinked ionic polyurethanes and copolyurethanes were yielded by reaction of telechelic cis-1,4-oligoisoprenes, bearing a variable number of ammonium and hydroxy groups, with isocyanurate of isophorone diisocyanate (I-IPDI). Aiming for a comparative study, polyurethane elastomers based on non-ionic telechelic o...

journal_title：Biomaterials

authors： Kébir N,Campistron I,Laguerre A,Pilard JF,Bunel C,Jouenne T

更新日期：2007-10-01 00:00:00