Challenge to the concept that UHMWPE acetabular components oxidize in vivo.

abstract：:The Raman laser and infrared spectra of doped bio-active glasses of the 45S5 type are presented and discussed. The spectroscopic results show that the doping agents cause the destruction of the basic glass structure and the consequent formation of SiO4(4-) units in the glass network. When the doped glasses have been i...

journal_title：Biomaterials

authors： Krajewski A,Ravaglioli A,Bertoluzza A,Monti P,Battaglia MA,Pizzoferrato A,Olmi R,Moroni A

更新日期：1988-11-01 00:00:00

abstract：:Immunotherapy has shown promising treatment effects for a variety of cancers. However, the immune treatment efficiency for solid tumors is limited owing to insufficient infiltration of immune cells into solid tumors. The conversion of tumor-supportive macrophages to tumor-suppressive macrophages, inducing the function...

journal_title：Biomaterials

authors： Wang Y,Lin YX,Qiao SL,An HW,Ma Y,Qiao ZY,Rajapaksha RP,Wang H

更新日期：2017-01-01 00:00:00

abstract：:A surface functionalization strategy that produces substrates with well-controlled ligand density is critical to investigating the role of cell-substrate interactions in regulating cell adhesion, viability, migration, proliferation and differentiation. Towards this end, we have designed and synthesized a triblock prot...

journal_title：Biomaterials

authors： Fischer SE,Liu X,Mao HQ,Harden JL

更新日期：2007-08-01 00:00:00

abstract：:The currently available surgical options to repair the diaphragm are associated with significant risks of defect recurrence, lack of growth potential and restored functionality. A tissue engineered diaphragm has the potential to improve surgical outcomes for patients with congenital or acquired disorders. Here we show...

journal_title：Biomaterials

authors： Gubareva EA,Sjöqvist S,Gilevich IV,Sotnichenko AS,Kuevda EV,Lim ML,Feliu N,Lemon G,Danilenko KA,Nakokhov RZ,Gumenyuk IS,Grigoriev TE,Krasheninnikov SV,Pokhotko AG,Basov AA,Dzhimak SS,Gustafsson Y,Bautista G,Beltrán Ro

更新日期：2016-01-01 00:00:00

abstract：:We studied non-implanted ultra-high molecular weight polyethylene (UHMWPE) knee components, that were gamma-sterilized in air and shelf-aged during 6 and 7 years, to explore fracture mechanisms in the degraded material. Prior to the fractography study, we assessed degradation through FTIR and optical density measureme...

journal_title：Biomaterials

authors： Puértolas JA,Larrea A,Gómez-Barrena E

更新日期：2001-08-01 00:00:00

abstract：:There is a great clinical need for tissue engineered blood vessels that could be used to replace or bypass damaged arteries. The success of such grafts will depend strongly on their ability to mimic the cellular and matrix organization found in native arteries, but currently available cell scaffolds such as electrospu...

journal_title：Biomaterials

authors： McClendon MT,Stupp SI

更新日期：2012-08-01 00:00:00

abstract：:Beads of polytetrafluoroethylene were used to investigate adsorption of thrombin and the influence of the adsorbed protease on a subsequent deposition of fibrinogen. Adsorption of active thrombin was not detected by a specific fluorogenic substrate unless > 0.1 units/ml had been applied. Adsorption was considerably im...

journal_title：Biomaterials

authors： Schlosser E,Simler R,Hörmann H

更新日期：1993-04-01 00:00:00

abstract：:The study was to produce a novel hybrid poly-(lactic-co-glycolic acid) (PLGA)-gelatin/chondroitin/hyaluronate (PLGA-GCH) scaffold and evaluate its potentials in cartilage repair. The porous PLGA-GCH scaffold was developed to mimic the natural extra cellular matrix of cartilage. The differentiated mesenchymal stem cell...

journal_title：Biomaterials

authors： Fan H,Hu Y,Zhang C,Li X,Lv R,Qin L,Zhu R

更新日期：2006-09-01 00:00:00

abstract：:Colloidal nanoparticle drug delivery systems have attracted much interest for their ability to enable effective formulation and delivery of therapeutic agents. The selective delivery of these nanoparticles to the disease site can be enhanced by coating the surface of the nanoparticles with targeting moieties, such as ...

journal_title：Biomaterials

authors： Fay F,McLaughlin KM,Small DM,Fennell DA,Johnston PG,Longley DB,Scott CJ

更新日期：2011-11-01 00:00:00

abstract：:Tissue engineering therapies targeted at nerve regeneration in spinal cord injuries (SCI) have broad social and economic benefits to the American population. Due to the complicated pathophysiology of SCI, there are very few options available for functional regeneration of the spinal column. Nanotechnology offers inter...

journal_title：Biomaterials

authors： Bechara SL,Judson A,Popat KC

更新日期：2010-05-01 00:00:00

abstract：:Block copolymer prodrugs (BCPs) have attracted considerable attentions in clinical translation of nanomedicine owing to their self-assembly into well-defined core-shell nanoparticles for improved pharmacokinetics, stability in blood circulation without drug leakage, and optimized biodistribution. However, a cascade of...

journal_title：Biomaterials

authors： Ke W,Yin W,Zha Z,Mukerabigwi JF,Chen W,Wang Y,He C,Ge Z

更新日期：2018-02-01 00:00:00

abstract：:Subtle changes on the surface of polymeric materials on autoclaving have been ignored so far. An increase in cyclic trimer content on the surface of polyethylene terephthalate on autoclaving is reported. This increase may affect the biocompatibility of polyethylene terephthalate. Quantification of the cyclic trimer wa...

journal_title：Biomaterials

authors： Nair PD,Sreenivasan K

更新日期：1984-09-01 00:00:00

abstract：:Bioabsorbable internal fixation devices were introduced clinically in the treatment of fractures and osteotomies of the extremities at the Department of Orthopaedics and Traumatology, Helsinki University, in 1984. Since November 5, 1984, a total of 3200 patients were managed using bone or ligament fixation devices mad...

journal_title：Biomaterials

authors： Rokkanen PU,Böstman O,Hirvensalo E,Mäkelä EA,Partio EK,Pätiälä H,Vainionpää SI,Vihtonen K,Törmälä P

更新日期：2000-12-01 00:00:00

abstract：:A genetically encoded Förster Resonance Energy Transfer (FRET)-based biosensor that continuously monitors matrix metalloproteinase 9 (MMP-9) activity was developed. MMP-9 is an extracellularly acting endopeptidase with a prominent role in development, learning and memory, cancer metastasis, and stroke. To assess the b...

journal_title：Biomaterials

authors： Stawarski M,Rutkowska-Wlodarczyk I,Zeug A,Bijata M,Madej H,Kaczmarek L,Wlodarczyk J

更新日期：2014-02-01 00:00:00

abstract：:In the present work, we designed and synthesized a novel mono-guanidine heterolipid (MGH) and confirmed its structure by NMR and ESI-MS. The MGH was used as cationic lipid in developing etoposide loaded cationic self-microemulsifying drug delivery system (ECS) intended to be delivered by intratumoral route. The ECS ex...

journal_title：Biomaterials

authors： Shete H,Sable S,Tidke P,Selkar N,Pawar Y,Chakraborty A,De A,Vanage G,Patravale V

更新日期：2015-07-01 00:00:00

abstract：:In ophthalmology, there is a need for novel degradable biomaterials for e.g. controlled drug release in the vitreous body. These degradable materials should feature both excellent biocompatibility, and well-defined kinetics of degradation. In most cases, poly(D,L-lactic acid), or poly(lactic-co-glycolic acid) are used...

journal_title：Biomaterials

authors： Bruining MJ,Blaauwgeers HG,Kuijer R,Pels E,Nuijts RM,Koole LH

更新日期：2000-03-01 00:00:00

abstract：:Vasculopathy due to ischemia in damaged tissues is a major cause of morbidity and mortality. To treat these conditions, endothelial progenitor cells (EPCs) from various sources, such as umbilical cord or peripheral blood, have been the focus of the regenerative medicine field due to their proliferative and vasculogeni...

journal_title：Biomaterials

authors： Kim J,Jeon YJ,Kim HE,Shin JM,Chung HM,Chae JI

更新日期：2013-02-01 00:00:00

abstract：:Remote microactuators are of great interest in biology and medicine as minimally-invasive tools for cellular stimulation. Remote actuation can be achieved by active magnetostrictive transducers which are capable of changing shape in response to external magnetic fields thereby creating controlled displacements. Among ...

journal_title：Biomaterials

authors： Vargas-Estevez C,Blanquer A,Dulal P,Pérez Del Real R,Duch M,Ibáñez E,Barrios L,Murillo G,Torras N,Nogués C,Stadler BJH,Plaza JA,Esteve J

更新日期：2017-09-01 00:00:00

abstract：:Interest in the identification and isolation of circulating tumor cells (CTCs) has been growing since the introduction of CTCs as an alternative to the tumor tissue biopsy, which can potentially be important indices for prognosis and cancer treatment. However, the contamination of non-specific binding of normal hemato...

journal_title：Biomaterials

authors： Wu JC,Tseng PY,Tsai WS,Liao MY,Lu SH,Frank CW,Chen JS,Wu HC,Chang YC

更新日期：2013-07-01 00:00:00

abstract：:To study the effect of ionizable functional groups on the adhesion of leucocytes to surfaces, both poly(ethyleneimine) and poly(acrylic acid) were immobilized on polyurethane films, resulting in the introduction of amine and carboxylic acid groups, respectively. This was confirmed by contact angle measurements and XPS...

journal_title：Biomaterials

authors： Bruil A,Terlingen JG,Beugeling T,van Aken WG,Feijen J

更新日期：1992-01-01 00:00:00

abstract：:The interest in gallium alloys as a replacement for amalgam has increased in recent years due to the risk of environmental pollution from amalgam. Alloy powders with compositions close to those for alloys of amalgam are mixed with a liquid gallium alloy. The mix is condensed into a prepared cavity in much the same way...

journal_title：Biomaterials

authors： Herø H,Simensen CJ,Jørgensen RB

更新日期：1996-07-01 00:00:00

abstract：:The potential for base poly(ethylene glycol) graft poly(acrylic acid) PEG-g-PA copolymers and surface-modified PEG-g-PA materials to inhibit random protein fouling and bacterial adhesion are investigated. PEG-g-PA co-polymers were synthesized that inhibited non-specific protein and cellular adhesion. PEG-g-PA co-polym...

journal_title：Biomaterials

authors： Wagner VE,Koberstein JT,Bryers JD

更新日期：2004-05-01 00:00:00

abstract：:In order to overcome the problem of rapid clearance of the polysaccharide hyaluronic acid (Hyal) in the treatment of osteoarthritis (OA), a 50% cross-linked Hyal hydrogel (Hyal 50%) was synthesised. The 50% refers to the amount of COOH groups of the polysaccharide involved in the cross-linking reaction. i.e. 50% of th...

journal_title：Biomaterials

authors： Barbucci R,Lamponi S,Borzacchiello A,Ambrosio L,Fini M,Torricelli P,Giardino R

更新日期：2002-12-01 00:00:00

abstract：:Tissue engineering and regenerative medicine technologies offer promising therapies for both medicine and dentistry. Our long-term goal is to create functional biomimetic tooth buds for eventual tooth replacement in humans. Here, our objective was to create a biomimetic 3D tooth bud model consisting of dental epitheli...

journal_title：Biomaterials

authors： Monteiro N,Smith EE,Angstadt S,Zhang W,Khademhosseini A,Yelick PC

更新日期：2016-11-01 00:00:00

abstract：:This paper describes a method of foaming a polymer system comprising poly(ethyl methacrylate)/tetrahydrofurfuryl methacrylate (PEMA/THFMA), characterisation of the resulting porosity and use of the foam for chondrocyte culture. The potential for this polymer system to support cartilage repair has been investigated pre...

journal_title：Biomaterials

authors： Barry JJ,Gidda HS,Scotchford CA,Howdle SM

更新日期：2004-08-01 00:00:00

abstract：:The creep strain rate and fracture of several dental amalgams has been shown to be markedly dependent on the type of loading applied. Cyclic loading typical of the in vivo situation increases creep rates and reduces times to fracture when analysis is based on a Mechanical Equation of State. The cyclic strain rate enha...

journal_title：Biomaterials

authors： Williams KR

更新日期：1983-10-01 00:00:00

abstract：:The superelastic nature of bones requires matching biomechanical properties from the ideal artificial biomedical implants in order to provide smooth load transfer and foster the growth of new bone tissues. In this work, we determine the biomechanical characteristics of porous NiTi implants and investigate bone ingrowt...

journal_title：Biomaterials

authors： Liu X,Wu S,Yeung KW,Chan YL,Hu T,Xu Z,Liu X,Chung JC,Cheung KM,Chu PK

更新日期：2011-01-01 00:00:00

abstract：:Premature ovarian failure (POF) is the most frequently occurred disease in ovary. Direct inhibition of mammalian target of rapamycin (mTOR) activity can treat woman POF but brings adverse effects to women. Herein, by rational design of a hydrogelator Nap-Phe-Phe-Asp-Arg-Leu-Tyr-OH (Y) and co-assembling Y with an inhib...

journal_title：Biomaterials

authors： Shi Z,Li X,Wei M,Chen P,Zhang T,Ling X,Zhang J,Zhao C,Wang F,Liang G

更新日期：2020-11-16 00:00:00

abstract：:Delivery of polynucleotide-based therapeutics into target cells involves interactions with glycosaminoglycan chains that are located on cell membrane milieu. Mechanisms governing glycosaminoglycan-mediated changes in the nanoparticulate structures of polymer-polynucleotide complexes are unknown, and cannot be fully el...

journal_title：Biomaterials

authors： Meneksedag-Erol D,Tang T,Uludağ H

更新日期：2018-02-01 00:00:00

abstract：:Radiolabeled nanomaterials, especially those with ultra-small structures, have been the research focus in recent years, and thus may open up new prospects for clinical diseases theranostics. Herein, fluorinated Pd nanosheets labeled with Gd or radionuclides are developed as multimodal platforms for tumor theranostics....

journal_title：Biomaterials

authors： Guo Z,Chen M,Peng C,Mo S,Shi C,Fu G,Wen X,Zhuang R,Su X,Liu T,Zheng N,Zhang X

更新日期：2018-10-01 00:00:00