Effect of steam sterilization on polyethylene terephthalate.

abstract：:Intracellular-acting therapeutic proteins offer a promising clinical alternative to extracellular-acting agents, but are limited in efficacy by their low permeability into the cell cytoplasm. We have developed a nanoparticle (NP) composed of lipid (DOTAP/DOPE) and apolipoprotein (APOA-I) to mediate the targeted delive...

journal_title：Biomaterials

authors： Kim SK,Foote MB,Huang L

更新日期：2012-05-01 00:00:00

abstract：:Nanomaterials with integrated multiple imaging and therapeutic modalities possess great potentials in accurate cancer diagnostics and enhanced therapeutic efficacy. Traditional strategies for achieving multimodality nanoplatform through one by one combination of different modalities are challenged by the complicated s...

journal_title：Biomaterials

authors： He X,Peng C,Qiang S,Xiong LH,Zhao Z,Wang Z,Kwok RTK,Lam JWY,Ma N,Tang BZ

更新日期：2020-04-01 00:00:00

abstract：:Low back pain is one of the most common medical conditions in the Western world. Disc degeneration, an inevitable process of aging, of variable rate and degree, is one of the major causes of low back pain. Currently, there are two major surgical interventions for treating conditions related to the degenerative disc: d...

journal_title：Biomaterials

authors： Bao QB,McCullen GM,Higham PA,Dumbleton JH,Yuan HA

更新日期：1996-06-01 00:00:00

abstract：:In this work, five self-assembled monolayers (SAMs) and three polymeric brushes with very low fibrinogen adsorption were prepared. The five SAMs are oligo(ethylene glycol) (OEG), phosphorylcholine (PC), oligo(phosphorylcholine) (OPC), and two mixed positively and negatively charged SAMs of SO(3)(-)/N(+)(CH(3))(3) (SA/...

journal_title：Biomaterials

authors： Zhang Z,Zhang M,Chen S,Horbett TA,Ratner BD,Jiang S

更新日期：2008-11-01 00:00:00

abstract：:The aim of this study was to characterize a nasally delivered bioadhesive liposome using an inactivated H5N3 virus as a model antigen. Bioadhesive liposomes were developed using tremella (T) or xanthan gum (XG) as the bioadhesive polysaccharide. Using chickens as the target animal, we evaluated whether delivery of a b...

journal_title：Biomaterials

authors： Chiou CJ,Tseng LP,Deng MC,Jiang PR,Tasi SL,Chung TW,Huang YY,Liu DZ

更新日期：2009-10-01 00:00:00

abstract：:An artificial receptor for creatinine was synthesized by the method of molecularly imprinted polymer (MIP). beta-Cyclodextrin was used as a monomer cross-linked with epichlorohydrin in the presence of creatinine, which was a template for the imprinting. Different molar ratios of monomer to template were used to synthe...

journal_title：Biomaterials

authors： Tsai HA,Syu MJ

更新日期：2005-05-01 00:00:00

abstract：:Although PEGylated TNF-related apoptosis-inducing ligand (PEG-TRAIL) has good tumor cell specificity and stability, its therapeutic potential is restricted by the development of tumor cell resistance. The purpose of this study was to develop an effective combination therapy with sustained biological activity based on ...

journal_title：Biomaterials

authors： Jiang HH,Kim TH,Lee S,Chen X,Youn YS,Lee KC

更新日期：2011-11-01 00:00:00

abstract：:A human-human oligodendroglial cell line MO3.13 was chosen in this study to model the loss of oligodendrocytes that occurs during episodes of multiple sclerosis. The influence of mercuric chloride (HgCl(2)) upon cell viability specifically the mode of cell death, whether by an active apoptotic mechanism or passive nec...

journal_title：Biomaterials

authors： Issa Y,Watts DC,Duxbury AJ,Brunton PA,Watson MB,Waters CM

更新日期：2003-03-01 00:00:00

abstract：:Ferroptosis, a newfound non-apoptotic cell death pathway, results from the accumulation of iron-dependent lipid peroxide (LPO). Recently, emerging iron-based nanomaterials have been extensively developed to induce Fenton reaction-dependent ferroptosis for cancer therapy. However, insufficient amount of H2O2 and limite...

journal_title：Biomaterials

authors： He YJ,Liu XY,Xing L,Wan X,Chang X,Jiang HL

更新日期：2020-05-01 00:00:00

abstract：:Matrix remodeling plays a fundamental role in physiological and pathological processes, as well as in tissue engineering applications. In this paper, optical coherence tomography (OCT), a non-destructive optical imaging technology, was used to image collagen gel remodeling by smooth muscle cells (SMCs). The optical sc...

journal_title：Biomaterials

authors： Levitz D,Hinds MT,Ardeshiri A,Hanson SR,Jacques SL

更新日期：2010-11-01 00:00:00

abstract：:Previous work developing particle-based acellular, artificial antigen presenting cells (aAPCs) has focused exclusively on spherical platforms. To explore the role of shape, we generated ellipsoidal PLGA microparticles with varying aspect ratios (ARs) and synthesized aAPCs from them. The ellipsoidal biomimetic aAPCs wi...

journal_title：Biomaterials

authors： Sunshine JC,Perica K,Schneck JP,Green JJ

更新日期：2014-01-01 00:00:00

abstract：:Polypyrrole (PPy) is a conducting polymer and is obtained electrochemically on an electrode such as indium-tin oxide (ITO). In this study, in order to develop a novel cell-culture system which makes it possible to communicate with cultured mammalian cells, bovine adrenal chromaffin cells were cultured on PPy-coated IT...

journal_title：Biomaterials

authors： Aoki T,Tanino M,Sanui K,Ogata N,Kumakura K

更新日期：1996-10-01 00:00:00

abstract：:Over the past two decades, in vitro autologous endothelial cell (EC) coverage of expanded polytetrafluoroethylene (ePTFE) graft has been developed and clinically applied with success in infrainguinal bypasses. Before endothelialization, the luminal surface of the graft has to be coated with a currently used fibrinolyt...

journal_title：Biomaterials

authors： Fernandez P,Deguette A,Pothuaud L,Belleannée G,Coste P,Bordenave L

更新日期：2005-08-01 00:00:00

abstract：:This work reports the development of new non-thrombogenic polymers based on the linear polymers of polyamidoamines (PAAs), having heparin binding ability, obtained by polyaddition of secondary amines to N,N'-methylene bis-acrylamide. PAAs could not be used directly in the making of blood-contacting materials due to th...

journal_title：Biomaterials

authors： Dey RK,Ray AR

更新日期：2003-08-01 00:00:00

abstract：:TiO(2)-coated biomaterials that have been excited with UV irradiation have demonstrated biocidal properties in environmental applications, including drinking water decontamination. However, this procedure has not been successfully applied towards the killing of pathogens on medical titanium-based implants, mainly beca...

journal_title：Biomaterials

authors： Gallardo-Moreno AM,Pacha-Olivenza MA,Fernández-Calderón MC,Pérez-Giraldo C,Bruque JM,González-Martín ML

更新日期：2010-07-01 00:00:00

abstract：:A major goal of bone tissue engineering is to design better scaffold configuration and materials to better control osteoblast behavior. Nanoporous architecture has been shown to significantly affect cellular response. In this work, nanoporous alumina membranes were fabricated by a two-step anodization method to invest...

journal_title：Biomaterials

authors： Popat KC,Leary Swan EE,Mukhatyar V,Chatvanichkul KI,Mor GK,Grimes CA,Desai TA

更新日期：2005-08-01 00:00:00

abstract：:Micropipette aspiration (MA) has been used extensively in biomechanical investigations of un-adhered cells suspended in media. In the current study, a custom MA system is developed to aspirate substrate adhered spread cells. Additionally, the system facilitates immuno-fluorescent staining of aspirated cells to investi...

journal_title：Biomaterials

authors： Reynolds NH,Ronan W,Dowling EP,Owens P,McMeeking RM,McGarry JP

更新日期：2014-04-01 00:00:00

abstract：:Permanent male sterilization has been recognized as useful tools for the development of neuter experimental animals and fattening livestock, as well as efficient control of pet overpopulation. Traditional routes such as surgical ways, chemical injections, and anti-fertility vaccines have addressed these crucial proble...

journal_title：Biomaterials

authors： Liu Z,Liu X,Ran X,Ju E,Ren J,Qu X

更新日期：2015-11-01 00:00:00

abstract：:CD47, a "don't eat me" signal, is over-expressed on the surface of most tumors that interacts with signal regulatory protein α (SIRPα) on phagocytic cells. By engaging SIRPα, CD47 limits the ability of macrophages to engulf tumor cells, which acts as a major phagocytic barrier. In this study, we developed an exosome-b...

journal_title：Biomaterials

authors： Koh E,Lee EJ,Nam GH,Hong Y,Cho E,Yang Y,Kim IS

更新日期：2017-03-01 00:00:00

abstract：:The study is focused on the evaluation of the potential bioadhesive behaviour of chitosan and thiolated chitosan (chitosan-TBA)-coated poly(isobutyl cyanoacrylates) (PIBCA) nanoparticles. Nanoparticles were obtained by radical emulsion polymerisation with chitosan of different molecular weight and with different propo...

journal_title：Biomaterials

authors： Bravo-Osuna I,Vauthier C,Farabollini A,Palmieri GF,Ponchel G

更新日期：2007-04-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC), as the fifth most common malignant cancer, develops and progresses mostly in a cirrhotic liver where stiff nodules are separated by fibrous bands. Scaffolds that can provide a 3D cirrhotic mechanical environment with complex native composition and biomimetic architecture are necessary f...

journal_title：Biomaterials

authors： Ma X,Yu C,Wang P,Xu W,Wan X,Lai CSE,Liu J,Koroleva-Maharajh A,Chen S

更新日期：2018-12-01 00:00:00

abstract：:Cancer stem cells (CSCs) play pivotal roles in cancer metastasis, and strategies targeting cancer stemness may greatly reduce cancer metastasis and improve patients' survival. The canonical Wnt/β-catenin pathway plays critical roles in CSC generation and maintenance as well as in normal stem cells. Non-specifically su...

journal_title：Biomaterials

authors： Li Y,Xiao Y,Lin HP,Reichel D,Bae Y,Lee EY,Jiang Y,Huang X,Yang C,Wang Z

更新日期：2019-01-01 00:00:00

abstract：:Dacron velour is often used to anchor a percutaneous device, like the catheter used in peritoneal dialysis. However, exit-site infections complicate this method of dialysis and are supposed to be related to the design of the catheter. In animal experiments, a percutaneous device provided with a titanium fibre mesh to ...

journal_title：Biomaterials

authors： Paquay YC,de Ruijter JE,van der Waerden JP,Jansen JA

更新日期：1996-06-01 00:00:00

abstract：:Extracellular matrix (ECM) based biomaterials have an established place as medical devices for wound healing and tissue regeneration. In the search for biomaterials we have identified ovine forestomach matrix (OFM), a thick, large format ECM which is biochemically diverse and biologically functional. OFM was purified ...

journal_title：Biomaterials

authors： Lun S,Irvine SM,Johnson KD,Fisher NJ,Floden EW,Negron L,Dempsey SG,McLaughlin RJ,Vasudevamurthy M,Ward BR,May BC

更新日期：2010-06-01 00:00:00

abstract：:Menisci are one of the most commonly injured parts of the knee with a limited healing potential. This study focuses on fabrication and characterization of biomimetic surfaces for meniscal tissue engineering. To achieve this, a combination of hyaluronic acid/chitosan (HA/CH) mutilayers with covalently immobilized major...

journal_title：Biomaterials

authors： Tan GK,Dinnes DL,Butler LN,Cooper-White JJ

更新日期：2010-08-01 00:00:00

abstract：:We determined whether a two-part space-conforming polyethylene glycol/dopa polymer-based gel promoted healing of contaminated wounds in mice. This silver-catalysed gel was previously developed to be broadly microbiocidal in vitro while being biocompatible with human wound cell functioning. Full-thickness wounds were c...

journal_title：Biomaterials

authors： Yates CC,Whaley D,Babu R,Zhang J,Krishna P,Beckman E,Pasculle AW,Wells A

更新日期：2007-09-01 00:00:00

abstract：:Restoration of tissue integrity and tissue function of wounded skin are both essential for wound repair and regeneration, while synergistic promotion of the two remains elusive. Since elevated reactive oxygen species (ROS) production in the injured site has been implicated in triggering a set of deleterious effects su...

journal_title：Biomaterials

authors： Wu H,Li F,Wang S,Lu J,Li J,Du Y,Sun X,Chen X,Gao J,Ling D

更新日期：2018-01-01 00:00:00

abstract：:Current tissue engineering strategies are focused on the restoration of pathologically altered tissue architecture by transplantation of cells in combination with supportive scaffolds and biomolecules. In recent years, considerable attention has been given to chitosan (CS)-based materials and their applications in the...

journal_title：Biomaterials

authors： Di Martino A,Sittinger M,Risbud MV

更新日期：2005-10-01 00:00:00

abstract：:While polymeric nano-formulations for RNAi therapeutics hold great promise for molecularly-targeted, personalized medicine, they possess significant systemic delivery challenges including rapid clearance from circulation and the potential for carrier-associated toxicity due to cationic polymer or lipid components. Her...

journal_title：Biomaterials

authors： Jackson MA,Bedingfield SK,Yu F,Stokan ME,Miles RE,Curvino EJ,Hoogenboezem EN,Bonami RH,Patel SS,Kendall PL,Giorgio TD,Duvall CL

更新日期：2019-02-01 00:00:00

abstract：:It has been demonstrated that using cultured chondrocytes that have been seeded onto various biomatrices can enhance the quality of the articular cartilage repair tissue. As tissue-engineering becomes increasingly more complex there is a need to understand how a specific biomaterial may influence gene expression. In t...

journal_title：Biomaterials

authors： Saldanha V,Grande DA

更新日期：2000-12-01 00:00:00