Synthesis, characterization, and blood compatibility of polyamidoamines copolymers.

abstract：:We have synthesized and characterized a novel peptide fluorosurfactant polymer (PFSP) modification that facilitates the adhesion and growth of endothelial cells on expanded polytetrafluoroetheylene (ePTFE) vascular graft material. This PFSP consists of a poly(vinyl amine) (PVAm) backbone with integrin binding Arg-Gly-...

journal_title：Biomaterials

authors： Larsen CC,Kligman F,Kottke-Marchant K,Marchant RE

更新日期：2006-10-01 00:00:00

abstract：:The in vivo evaluation, in New Zealand rabbits, of a SiO(2)-P(2)O(5)-CaO sol-gel glass and a SiO(2)-P(2)O(5)-CaO-MgO glass-ceramic, both bioactive in Kokubo's simulated body fluid (SBF), is presented. Bone defects, performed in the lateral aspect of distal right femoral epiphysis, 5mm in diameter and 4mm in depth, wer...

journal_title：Biomaterials

authors： Gil-Albarova J,Garrido-Lahiguera R,Salinas AJ,Román J,Bueno-Lozano AL,Gil-Albarova R,Vallet-Regí M

更新日期：2004-08-01 00:00:00

abstract：:Micropipette aspiration (MA) has been used extensively in biomechanical investigations of un-adhered cells suspended in media. In the current study, a custom MA system is developed to aspirate substrate adhered spread cells. Additionally, the system facilitates immuno-fluorescent staining of aspirated cells to investi...

journal_title：Biomaterials

authors： Reynolds NH,Ronan W,Dowling EP,Owens P,McMeeking RM,McGarry JP

更新日期：2014-04-01 00:00:00

abstract：:Chitosan-based nanofibers with an average fiber diameter controllable from a few microns down to approximately 40 nm and a narrow size distribution were fabricated by electrospinning solutions containing chitosan, polyethylene oxide (PEO), and Triton X-100. Rheological study showed a strong dependence of spinnability ...

journal_title：Biomaterials

authors： Bhattarai N,Edmondson D,Veiseh O,Matsen FA,Zhang M

更新日期：2005-11-01 00:00:00

abstract：:In this paper we describe the mechanical and biological features of a thermosetting polyester synthesized from glycerol and dodecanedioic acid named Poly-Glycerol-Dodecanoate (PGD). This polymer shows a glass transition temperature (T(g)) around 32 degrees C, and this accounts for its mechanical properties. At room te...

journal_title：Biomaterials

authors： Migneco F,Huang YC,Birla RK,Hollister SJ

更新日期：2009-11-01 00:00:00

abstract：:Mesenchymal stromal/stem cell (MSC)-based therapy is a promising approach for the treatment of heart failure. However, current MSC-delivery methods result in poor donor cell engraftment, limiting the therapeutic efficacy. To address this issue, we introduce here a novel technique, epicardial placement of bi-layered, a...

journal_title：Biomaterials

authors： Kobayashi K,Ichihara Y,Sato N,Umeda N,Fields L,Fukumitsu M,Tago Y,Ito T,Kainuma S,Podaru M,Lewis-McDougall F,Yamahara K,Uppal R,Suzuki K

更新日期：2019-07-01 00:00:00

abstract：:Optimal nano-sized drug carrier requires long blood circulation, selective extravasation, and efficient cell uptake. Here we develop a charge-convertible nanoplatform based on Pt(IV) prodrug loaded NaYF4:Yb,Tm upconversion nanoparticles (UCNs), followed by coating a layer of PEG-PAH-DMMA polymer (UCNs-Pt(IV)@PEG-PAH-D...

journal_title：Biomaterials

authors： Xu J,Kuang Y,Lv R,Yang P,Li C,Bi H,Liu B,Yang D,Dai Y,Gai S,He F,Xing B,Lin J

更新日期：2017-06-01 00:00:00

abstract：:The significant drawbacks and lack of success associated with current methods to treat critically sized nerve defects have led to increased interest in neural tissue engineering. Conducting polymers show great promise due to their electrical properties, and in the case of polypyrrole (PPY), its cell compatibility as w...

journal_title：Biomaterials

authors： Xu H,Holzwarth JM,Yan Y,Xu P,Zheng H,Yin Y,Li S,Ma PX

更新日期：2014-01-01 00:00:00

abstract：:The incidence of Parkinson's disease (PD), the second most common neurodegenerative disorder, has increased exponentially as the global population continues to age. Although the etiological factors contributing to PD remain uncertain, its average incidence rate is reported to be 1% of the global population older than ...

journal_title：Biomaterials

authors： Karthivashan G,Ganesan P,Park SY,Lee HW,Choi DK

更新日期：2020-02-01 00:00:00

abstract：:Polypyrrole (PPy) is a conducting polymer and is obtained electrochemically on an electrode such as indium-tin oxide (ITO). In this study, in order to develop a novel cell-culture system which makes it possible to communicate with cultured mammalian cells, bovine adrenal chromaffin cells were cultured on PPy-coated IT...

journal_title：Biomaterials

authors： Aoki T,Tanino M,Sanui K,Ogata N,Kumakura K

更新日期：1996-10-01 00:00:00

abstract：:A lipid/calcium/phosphate (LCP) nanoparticle (NP) formulation (particle diameter ∼25 nm) with superior siRNA delivery efficiency was developed and reported previously. Here, we describe the successful formulation of (111)In into LCP for SPECT/CT imaging. Imaging and biodistribution studies showed that, polyethylene gl...

journal_title：Biomaterials

authors： Tseng YC,Xu Z,Guley K,Yuan H,Huang L

更新日期：2014-05-01 00:00:00

abstract：:Mucus layer coating the vaginal epithelium represents a barrier for intravaginally delivered recombined adenoviral (rAd) vectors, but it could be overcome by proper polyethylene glycol (PEG) modification. Here we synthesized two cationic PEG derivatives, amino-(EO)n/(AGE)m-Cyss (APCs). The polymers contained neutral l...

journal_title：Biomaterials

authors： Xie Z,Ji Z,Zhang Z,Gong T,Sun X

更新日期：2014-09-01 00:00:00

abstract：:Highly cross-linked aliphatic polyurethane networks have been prepared by the bulk step reaction of low molecular weight polyols and hexamethylenediisocyanate (HDI). These polyurethane networks are optically transparent, colourless and autoclavable amorphous glassy thermosets, which are suited for use in ophthalmic ap...

journal_title：Biomaterials

authors： Bruin P,Meeuwsen EA,van Andel MV,Worst JG,Pennings AJ

更新日期：1993-11-01 00:00:00

abstract：:In arterial replacement there is a clear clinical need for a functional substitute possessing appropriate haemocompatible properties to be implanted as small diameter artery. Endothelial cell seeding constitutes an appreciated method to improve blood compatibility on the condition that cells firmly adhere to the suppo...

journal_title：Biomaterials

authors： Rémy M,Durand M,Menu P,Voegel JC,Ponsot JF,Bérard X,Harmand MF,Bordenave L

更新日期：2013-12-01 00:00:00

abstract：:Peel bond strength and tensile bond strength between three polyvinylsiloxane denture soft liners and a heat-cured acrylic resin denture base were measured using two adhesive systems. The soft lining materials differed only in regard of their filler content and compliance. The values of bond strength and mode of failur...

journal_title：Biomaterials

authors： McCabe JF,Carrick TE,Kamohara H

更新日期：2002-03-01 00:00:00

abstract：:Multiblock, high molecular weight, linear, backbone degradable HPMA copolymer-prostaglandin E1 (PGE1) conjugate has been synthesized by RAFT polymerization mediated by a new bifunctional chain transfer agent (CTA), which contains an enzymatically degradable oligopeptide sequence flanked by two dithiobenzoate groups, f...

journal_title：Biomaterials

authors： Pan H,Sima M,Miller SC,Kopečková P,Yang J,Kopeček J

更新日期：2013-09-01 00:00:00

abstract：:We compared the osteogenic response in porous alumni (Al) and hydroxyapatite coated porous alumni ceramic (HA/Al) by grafting rat bone marrow cells with these implants subcutaneously in the back of syngeneic rats. The ceramics did not show any bone formation without marrow, but did when combined with marrow cells. The...

journal_title：Biomaterials

authors： Takaoka T,Okumura M,Ohgushi H,Inoue K,Takakura Y,Tamai S

更新日期：1996-08-01 00:00:00

abstract：:The cytocompatibility of amphiphilic, thermoresponsive and chemically crosslinkable macromers was examined in vitro. Macromers synthesized from pentaerythritol diacrylate monostearate, N-isopropylacrylamide, acrylamide and hydroxyethyl acrylate in different molar ratios and with varying molecular weights and lower cri...

journal_title：Biomaterials

authors： Klouda L,Hacker MC,Kretlow JD,Mikos AG

更新日期：2009-09-01 00:00:00

abstract：:We have used a new synthetic injectable composite constituted of hydroxyapatite/tricalcium phosphate (HA/TCP) particles in suspension in a self-hardening Si-hydroxypropylmethylcellulose (HPMC) hydrogel. The aim of this study was to evaluate in vivo the biocompatibility and the new bone formation efficacy of this scaff...

journal_title：Biomaterials

authors： Trojani C,Boukhechba F,Scimeca JC,Vandenbos F,Michiels JF,Daculsi G,Boileau P,Weiss P,Carle GF,Rochet N

更新日期：2006-06-01 00:00:00

abstract：:Constitutive models are developed, based on the results of confined compression testing, to describe the visco-elastic, and non-linear elasto-plastic behaviour of morsellised cortico-cancellous bone (MCB). It is found that the elastic modulus, E of MCB can be expressed as a linear function of the applied pressure, p. ...

journal_title：Biomaterials

authors： Phillips A,Pankaj P,May F,Taylor K,Howie C,Usmani A

更新日期：2006-03-01 00:00:00

abstract：:Hematopoietic stem cells (HSCs) are the vital, life-long source of all blood cell types. They are found in stem cell niches, specific anatomic locations that offer all the factors and signals necessary for the maintenance of the stem cell potential of HSCs. Much attention has been paid to the biochemical composition o...

journal_title：Biomaterials

authors： Altrock E,Muth CA,Klein G,Spatz JP,Lee-Thedieck C

更新日期：2012-04-01 00:00:00

abstract：:Although PEGylated liposomes (PEG-LS) have been intensively studied as drug-delivery vehicles, the rigidity and the hydrophilic PEG corona of liposomal membranes often limits cellular uptake, resulting in insufficient drug delivery to target cells. Thus, it is necessary to develop a new type of lipid-based self-assemb...

journal_title：Biomaterials

authors： Saw PE,Yu M,Choi M,Lee E,Jon S,Farokhzad OC

更新日期：2017-04-01 00:00:00

abstract：:The aim of this study was to follow the in vivo biodegradation as well as to appreciate the brain tissue response to poly(methylidene malonate 2.1.2) (PMM 2.1.2)-based microspheres implanted into the rat brain. Ninety-three adult Sprague-Dawley female rats were engaged in the study in which 54 underwent stereotactic i...

journal_title：Biomaterials

authors： Fournier E,Passirani C,Colin N,Sagodira S,Menei P,Benoit JP,Montero-Menei CN

更新日期：2006-10-01 00:00:00

abstract：:The creation of 3D scaffolds that mimic the structure of physiological tissue required for normal cell function is a major bioengineering challenge. For corneal stroma reconstruction this necessitates the creation of a stroma-like scaffold consisting of a stack of orthogonally disposed sheets of aligned collagen fibri...

journal_title：Biomaterials

authors： Torbet J,Malbouyres M,Builles N,Justin V,Roulet M,Damour O,Oldberg A,Ruggiero F,Hulmes DJ

更新日期：2007-10-01 00:00:00

abstract：:The foreign body reactions to collagen-immobilized polyurethane (PU-CI) films during subcutaneous implantation in rats were characterized. The underlying concept is that collagen-immobilization will improve the tissue integration. Since the method of collagen-immobilization involves the covalent coupling of collagen t...

journal_title：Biomaterials

authors： van Wachem PB,Hendriks M,Blaauw EH,Dijk F,Verhoeven ML,Cahalan PT,van Luyn MJ

更新日期：2002-03-01 00:00:00

abstract：:The removal of tenacious dental plaque is of paramount importance; however, early diagnosis can be a challenging task in dental clinics due to the limitations of current approaches, specifically X-ray-based techniques. We have approached this problem by integrating antibacterial properties and X-ray contrast enhanceme...

journal_title：Biomaterials

authors： Ostadhossein F,Misra SK,Tripathi I,Kravchuk V,Vulugundam G,LoBato D,Selmic LE,Pan D

更新日期：2018-10-01 00:00:00

abstract：:Type I collagen constitutes a major portion of the extracellular matrix (ECM) in arterial wall and it is the major substrate for cell growth and differentiation. The goal of this study was to evaluate the differentiation and proliferation of placenta-derived multipotent cells (PDMCs) on polymerized type I collagen fib...

journal_title：Biomaterials

authors： Chou MT,Chang SN,Ke C,Chang HI,Sung ML,Kuo HC,Chen CN

更新日期：2010-05-01 00:00:00

abstract：:Biomimetic strategies focusing on presenting short bioadhesive oligopeptides, including the arginine-glycine-aspartic acid (RGD) motif present in numerous adhesive proteins, on a non-fouling support have emerged as promising approaches to improve cellular activities and healing responses. Nevertheless, these bio-inspi...

journal_title：Biomaterials

authors： Petrie TA,Capadona JR,Reyes CD,García AJ

更新日期：2006-11-01 00:00:00

abstract：:Bone tissue engineering strategies are fundamentally based upon porous scaffold materials that serve as a support for ingrowth of host cells and/or provide a substrate for exogenously delivered cells. Here we report the application of a surface calcium phosphate (CaP) mineral layer to a macroporous polymeric/CaP compo...

journal_title：Biomaterials

authors： Lickorish D,Guan L,Davies JE

更新日期：2007-03-01 00:00:00

abstract：:The present study deals with the synthesis and characterization of radiopaque polymers which could, when solubilized in an appropriate water-miscible solvent, be useful embolic materials for the treatment of cerebral aneurysms and arteriovenous malformations. For this purpose cellulose (both microcrystalline and powde...

journal_title：Biomaterials

authors： Mottu F,Rüfenacht DA,Laurent A,Doelker E

更新日期：2002-01-01 00:00:00