Abstract:
:Reactive oxygen species (ROS) are generated during T cell activation and serve a signaling function but can also be damaging. In this issue of Immunity, Zhang et al. (2016) show that miR-23a prevents ROS-elicited necrosis by suppressing cyclophilin D (PPIF), a regulator of ROS escape from mitochondria.
journal_name
Immunityjournal_title
Immunityauthors
Agudo J,Brown BDdoi
10.1016/j.immuni.2016.02.027subject
Has Abstractpub_date
2016-03-15 00:00:00pages
520-522issue
3eissn
1074-7613issn
1097-4180pii
S1074-7613(16)30066-8journal_volume
44pub_type
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