Abstract：
:Nanofabrication has seen an increasing demand for applications in many fields of science and technology, but its production still requires relatively difficult, time-consuming, and expensive processes. Here we report a simple but very effective one dimensional (1D) nano-patterning technology that suggests a new nanofabrication method. This new technique involves the control of naturally propagating cracks initiated through simple, manually generated indentation, obviating the necessity of complicated equipment and elaborate experimental environments such as those that employ clean rooms, high vacuums, and the fastidious maintenance of processing temperatures. The channel fabricated with this technique can be as narrow as 10 nm with unlimited length and very high cross-sectional aspect ratio, an accomplishment difficult even for a state-of-the-art technology such as e-beam lithography. More interestingly, the fabrication speed can be controlled and achieved to as little as several hundred micrometers per second. Along with the simplicity and real-time fabrication capability of the technique, this tunable fabrication speed makes the method introduced here the authentic nanofabrication for in situ experiments.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Nam KH,Suh YD,Yeo J,Woo Ddoi
10.1038/srep18892subject
Has Abstractpub_date
2016-01-04 00:00:00pages
18892issn
2045-2322pii
srep18892journal_volume
6pub_type
杂志文章abstract：:Intervertebral disc (IVD) degeneration is a leading cause of chronic low back pain that affects millions of people every year. Yet identification of the specific IVD causing this pain is based on qualitative visual interpretation rather than objective findings. One possible approach to diagnosing pain-associated IVD c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-34582-6
更新日期：2018-11-26 00:00:00
abstract：:Plant resistance can provide effective, economical, and sustainable pest control. Tolerance to the soybean aphid has been identified and confirmed in the soybean KS4202. Although its resistance mechanisms are not fully understood, evidence suggests that enhanced detoxification of reactive oxygen species (ROS) is an ac...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-33477-w
更新日期：2018-10-11 00:00:00
abstract：:Pyoverdine (PVDI) has been reported to act both as a siderophore for scavenging iron (a key nutrient) and a signaling molecule for the expression of virulence factors. This compound is itself part of a core set of virulence factors produced by Pseudomonas aeruginosa during infections. Once secreted into the bacterial ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-56913-x
更新日期：2020-01-10 00:00:00
abstract：:The western North-Atlantic coast experienced major coastal floods in recent years. Coastal floods are primarily composed of tides and storm surges due to tropical (TCs) and extra-tropical cyclones (ETCs). We present a reanalysis from 1988 to 2015 of extreme sea levels that explicitly include TCs for the western North-...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-40157-w
更新日期：2019-03-04 00:00:00
abstract：:We demonstrate an experimental methodology for measuring the temporal distribution of pico-second level electron bunch with low energy using radial electric and azimuthal magnetic fields of an accelerating ([Formula: see text] mode) radio frequency (RF) cavity that is used for accelerating electron beams in a linear a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76054-w
更新日期：2020-11-03 00:00:00
abstract：:The renal sodium chloride cotransporter, NCC, in the distal convoluted tubule is important for maintaining body Na+ and K+ homeostasis. Endogenous NCC is highly ubiquitylated, but the role of individual ubiquitylation sites is not established. Here, we assessed the role of 10 ubiquitylation sites for NCC function. Tra...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-12819-0
更新日期：2017-10-11 00:00:00
abstract：:The present work aimed to investigate the activities and underlying mechanisms of dioscin against alcoholic liver fibrosis (ALF). In vivo liver fibrosis in mice was induced by an alcoholic liquid diet, and in vitro studies were performed on activated HSC-T6 and LX2 cells treated with lipopolysaccharide. Our results sh...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep18038
更新日期：2015-12-10 00:00:00
abstract：:Bats are the only mammals capable of true, powered flight, which drives an extremely high metabolic rate. The "Free Radical Theory of Ageing" (FTRA) posits that a high metabolic rate causes mitochondrial heteroplasmy and the progressive ageing phenotype. Contrary to this, bats are the longest-lived order of mammals gi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-31093-2
更新日期：2018-09-11 00:00:00
abstract：:Transgenic sheep can be used to achieve genetic improvements in breeds and as an important large-animal model for biomedical research. In this study, we generated a TALEN plasmid specific for ovine MSTN and transfected it into fetal fibroblast cells of STH sheep. MSTN biallelic-KO somatic cells were selected as nuclea...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep33675
更新日期：2016-09-22 00:00:00
abstract：:X-ray phase-contrast imaging (XPCI) can dramatically improve soft tissue contrast in X-ray medical imaging. Despite worldwide efforts to develop novel XPCI systems, a numerical framework to rigorously predict the performance of a clinical XPCI system at a human scale is not yet available. We have developed such a tool...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep12011
更新日期：2015-07-14 00:00:00
abstract：:When making decisions, humans can maximize the positive outcome of their actions by choosing the option associated with the highest reward. We have recently shown that choices modulate effects of reward via a bias in spatial attention: Locations associated with a lower reward are anticipatorily suppressed, as indicate...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-42255-1
更新日期：2019-04-08 00:00:00
abstract：:Fine particulate matter 2.5 (PM2.5) induces free radicals and oxidative stress in animals, leading to a range of illnesses. In this study, Ganoderma Microsporum immunomodulatory (GMI) proteins were administered to alleviate PM2.5-induced inflammatory responses in mother rats, and PM2.5-induced inflammatory responses a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-38810-5
更新日期：2019-05-02 00:00:00
abstract：:The prefrontal cortex (PF) is involved in outcome-based flexible adaptation in a dynamically changing environment. The outcome signal dissipates gradually over time, but the temporal dynamics of this dissipation remains unknown. To examine this issue, we analyzed the outcome-related activity of PF neurons in 2 monkeys...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep25622
更新日期：2016-05-10 00:00:00
abstract：:Performance of a recently developed test for association between multivariate phenotypes and sets of genetic variants (MURAT) is demonstrated using measures of bone mineral density (BMD). By combining individual-level whole genome sequenced data from the UK10K study, and imputed genome-wide genetic data on individuals...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-18385-9
更新日期：2018-01-09 00:00:00
abstract：:This work aimed to investigate the co-grinding effects of β-cyclodextrin (β-CD) and cucurbit[7]uril (CB[7]) on crystalline zaltoprofen (ZPF) in tablet formulation. Crystalline ZPF was prepared through anti-solvent recrystallization and fully analyzed through single-crystal X-ray diffraction. Co-ground dispersions and ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep45984
更新日期：2017-04-03 00:00:00
abstract：:Channelrhodopsins are light-gated ion channels of green algae used for the precise temporal and spatial control of transmembrane ion fluxes. The channelrhodopsin Chrimson from Chlamydomonas noctigama allows unprecedented deep tissue penetration due to peak absorption at 590 nm. We demonstrate by electrophysiological r...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-09600-8
更新日期：2017-08-30 00:00:00
abstract：:A spontaneous exchange bias (SEB) discovered by Wang et al. [Phys. Rev. Lett. 106 (2011) 077203.] after zero-field cooling (ZFC) has attracted recent attention due to its interesting physics. In this letter, we report a giant SEB tuned by Sb-doping in Ni50Mn38Ga12-xSbx Heusler alloys. Such an SEB was switched on below...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep30801
更新日期：2016-08-01 00:00:00
abstract：:Selective filtration of gas, water, and liquid or gaseous oil is essential to prevent possible environmental pollution and machine/facility malfunction in oil-based industries. Novel materials and structures able to selectively and efficiently filter liquid and vapor in various types of solutions are therefore in cont...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep14321
更新日期：2015-09-23 00:00:00
abstract：:We have recently demonstrated that the rate-limiting enzymes in human glucose metabolism organize into cytoplasmic clusters to form a multienzyme complex, the glucosome, in at least three different sizes. Quantitative high-content imaging data support a hypothesis that the glucosome clusters regulate the direction of ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-20348-7
更新日期：2018-02-09 00:00:00
abstract：:In this paper, for the first time, the switchable two-color quantum dot laser has been realized considering solution process technology, which has both simultaneous and lonely lasing capability exploiting selective energy contacts. Furthermore, both channels can be modulated independently, which is a significant featu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-60859-w
更新日期：2020-03-24 00:00:00
abstract：:2-Bromo-5-(2-bromo-2-nitrovinyl)furan (G1 or Furvina) is an antimicrobial with a direct reactivity against thiol groups. It is active against Gram-positive and Gram-negative bacteria, yeasts and filamentous fungi. By reacting with thiol groups it causes direct damage to proteins but, as a result, is very short-living ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep36844
更新日期：2016-11-10 00:00:00
abstract：:High temperature inhibits wheat grain filling. Polyamines (PAs) are closely associated with plant resistance caused by abiotic stress. However, little is known about the effect of PAs on the grain filling of wheat under heat stress. Two wheat varieties differing in heat resistance were used, and endogenous PAs levels ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-64468-5
更新日期：2020-05-04 00:00:00
abstract：:Our previous studies demonstrated that volatile oil from saussurea lappa root (VOSL), rich in two natural sesquiterpene lactones, costunolide (Cos) and dehydrocostuslactone (Dehy), exerts better anti-breast cancer efficacy and lower side effects than Cos or Dehy alone in vivo, however, their anti-cancer molecular mech...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep41254
更新日期：2017-01-24 00:00:00
abstract：:We evaluated the performance of CSF biomarkers for predicting risk of clinical decline and conversion to dementia in non-demented patients with cognitive symptoms. CSF samples from patients in two multicentre longitudinal studies (ADNI, n = 619; BioFINDER, n = 431) were analysed. Aβ(1-42), tTau and pTau CSF concentrat...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-54204-z
更新日期：2019-12-13 00:00:00
abstract：:Herein, we have fabricated rutile TiO2 nanorod-coupled α-Fe2O3 by a wet-chemical process. It is demonstrated that the visible activities for photoelectrochemical water oxidation and for degrading pollutant of α-Fe2O3 are greatly enhanced after coupling a proper amount of rutile nanorods. The enhanced activity is attri...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep06180
更新日期：2014-08-26 00:00:00
abstract：:Adipose tissue plays a major role in regulating whole-body insulin sensitivity and energy metabolism. To accommodate surplus energy, the tissue rapidly expands by increasing adipose cell size (hypertrophy) and cell number (hyperplasia). Previous studies have shown that enlarged, hypertrophic adipocytes are less respon...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-49418-0
更新日期：2019-09-10 00:00:00
abstract：:RNA editing is a molecular event that alters specific nucleotides in RNA post-transcriptionally. RNA editing has the potential to impact a variety of cellular processes and is implicated in diseases such as cancer. Yet, the precise mechanisms by which RNA editing controls cellular processes are poorly understood. Here...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep23226
更新日期：2016-03-16 00:00:00
abstract：:A novel ignition hohlraum for indirect-drive inertial confinement fusion is proposed, which is named three-axis cylindrical hohlraum (TACH). TACH is a kind of 6 laser entrance holes (LEHs) hohlraum, which is orthogonally jointed of three cylindrical hohlraums. Laser beams are injected through every entrance hole with ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep34636
更新日期：2016-10-05 00:00:00
abstract：:Prolonged tomato consumption can mitigate ultraviolet (UV) light induced sunburn via unknown mechanisms. Dietary carotenoids distributed to skin are hypothesized to protect skin against UV-induced damage, although other phytochemicals may play a role. We hypothesize that tomato consumption would protect against skin c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-05568-7
更新日期：2017-07-11 00:00:00
abstract：:Iron oxide nanoparticles have attracted a great deal of research interest and have been widely used in bioscience and clinical research including as contrast agents for magnetic resonance imaging, hyperthermia and magnetic field assisted radionuclide therapy. It is therefore important to develop methods, which can pro...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-25852-4
更新日期：2018-05-10 00:00:00
