Abstract:
:Fine particulate matter 2.5 (PM2.5) induces free radicals and oxidative stress in animals, leading to a range of illnesses. In this study, Ganoderma Microsporum immunomodulatory (GMI) proteins were administered to alleviate PM2.5-induced inflammatory responses in mother rats, and PM2.5-induced inflammatory responses and neurological damage in their offspring. The results suggested that GMI administration decreased the risk of neurological disorders in mother rats and their offspring by reducing the white blood cell count, lessening inflammatory responses and PM2.5-induced memory impairment, and preventing dendritic branches in the hippocampi from declining and microRNAs from PM2.5-induced modulation.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Tseng CY,Yu JY,Chuang YC,Lin CY,Wu CH,Liao CW,Yang FH,Chao MWdoi
10.1038/s41598-019-38810-5subject
Has Abstractpub_date
2019-05-02 00:00:00pages
6854issue
1issn
2045-2322pii
10.1038/s41598-019-38810-5journal_volume
9pub_type
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