Genetic and antigenic comparison of Streptococcus mutans fructosyltransferase and glucan-binding protein.

Abstract:

:The genes for fructosyltransferase (ftf) and glucan-binding protein (gbp) of Streptococcus mutans strain Ingbritt have been cloned in E. coli using bacteriophage and plasmid vectors. A single ftf gene appears to be responsible for the appearance of several FTF of different electrophoretic mobilities. Despite the fact that both ftf and gbp proteins synthesise fructans from sucrose in S. mutans and shown closely similar electrophoretic mobilities and isoelectric points, the restriction maps of the two genes are distinct, their DNAs do not hybridise and there is no immunological cross-reaction between the two proteins.

journal_name

FEMS Microbiol Lett

authors

Aduse-Opoku J,Gilpin ML,Russell RR

doi

10.1016/0378-1097(89)90432-1

subject

Has Abstract

pub_date

1989-06-01 00:00:00

pages

279-82

issue

3

eissn

0378-1097

issn

1574-6968

journal_volume

50

pub_type

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