Changes in fatty acid composition associated with differentiation of Trypanosoma cruzi.

Abstract:

:The fatty acid composition during the transformation of Trypanosoma cruzi epimastigotes into metacyclic trypomastigotes (metacyclogenesis) was analysed by gas-liquid chromatography and mass spectrometry. Significant qualitative and quantitative changes in the fatty acid composition occurred during incubation of epimastigotes derived from LIT medium in the triatomine artificial urine (TAU). Metacyclogenesis was also followed by alterations in the fatty acid pattern but these were considerably less pronounced when compared to the pattern obtained for TAU-incubated epimastigotes. These results suggest that changes in the lipid composition precede the morphological transformation of epimastigotes into metacyclic trypomastigotes.

journal_name

FEMS Microbiol Lett

authors

Esteves MG,Gonzales-Perdomo M,Alviano CS,Angluster J,Goldenberg S

doi

10.1016/0378-1097(89)90453-9

subject

Has Abstract

pub_date

1989-05-01 00:00:00

pages

31-4

issue

1-2

eissn

0378-1097

issn

1574-6968

journal_volume

50

pub_type

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