Diversity of CTX-M beta-lactamases and their promoter regions from Enterobacteriaceae isolated in three Parisian hospitals.


:Nine clinical isolates of Enterobacteriaceae (six Escherichia coli and three Proteus mirabilis) isolated in three Parisian hospitals between 1989 and 2000 showed a particular extended-spectrum cephalosporin-resistance profile characterized by resistance to cefotaxime and aztreonam but not to ceftazidime. CTX-M-1, CTX-M-2, CTX-M-9, CTX-M-14 and two novel plasmid-mediated CTX-M beta-lactamases (CTX-M-20, and CTX-M-21) were identified by polymerase chain reaction and isoelectric focusing (pI>8) and were associated in eight cases with TEM-1 (pI=5.4) or TEM-2 (pI=5.6) beta-lactamases. We used internal ISEcp1 and IS26 forward primers and the CTX-M consensus reverse primer to characterize the CTX-M beta-lactamase promoter regions and showed their high degree of structure diversity. We found upstream of some bla(CTX-M) genes, a 266-bp sequence 100% identical to the sequence upstream of the Kluyvera ascorbata beta-lactamase gene, suggesting that this chromosomal enzyme is the progenitor of the CTX-M-2/5 cluster.


FEMS Microbiol Lett


Saladin M,Cao VT,Lambert T,Donay JL,Herrmann JL,Ould-Hocine Z,Verdet C,Delisle F,Philippon A,Arlet G





Has Abstract


2002-04-09 00:00:00














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    abstract::Alkyl ether-degrading Rhodococcus sp. strain DEE5151, isolated from activated sewage sludge, has an activity for the oxidation of a variety of alkyl ethers, aralkyl ethers and dibenzyl ether. The whole cell activity for diethyl ether oxidation was effectively inhibited by 2,3-dihydrofurane, ethyl vinyl ether and gluta...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Kim YH,Engesser KH

    更新日期:2005-02-15 00:00:00

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    abstract::The surface adhesin P97 mediates the adherence of Mycoplasma hyopneumoniae to swine cilia. Two reiterated repeats R1 and R2 are located at the C-terminus of P97. The purpose of this study was to evaluate the immunogenicity of Montanide adjuvant IMS 1113 plus soluble subunit proteins rR1, rR1R2 and their chimeric forms...

    journal_title:FEMS microbiology letters

    pub_type: 信件


    authors: Barate AK,Cho Y,Truong QL,Hahn TW

    更新日期:2014-03-01 00:00:00

  • The 70 kilodalton iron regulated protein of Neisseria meningitidis is not the human transferrin receptor.

    abstract::Neisseria meningitidis is able to chelate iron from human transferrin (HTF), the main sequestrator of extracellular iron in vivo. Previous workers have reported that a ca. 70 kilodalton (kDa) iron regulated outer membrane protein (FeRP-70) is a highly specific receptor for HTF. We have examined the interaction between...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Ala'Aldeen DA,Davies HA,Wall RA,Borriello SP

    更新日期:1990-05-01 00:00:00

  • Quantitative polymerase chain reaction used for the rapid detection of Carnobacterium species from French soft cheeses.

    abstract::An identification method by PCR, specific to the Carnobacterium genus, was optimised by testing it on 28 bacterial strains. Primers from the literature were tested to differentiate Carnobacterium strains present among various bacterial species. The DNA of Carnobacterium species (C. alterfunditum, C. divergens, C. fund...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Cailliez-Grimal C,Miguindou-Mabiala R,Leseine M,Revol-Junelles AM,Millière JB

    更新日期:2005-09-01 00:00:00

  • Aerobic microbial communities in the sediments of a marine oxygen minimum zone.

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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Bhattacharya S,Roy C,Mandal S,Sarkar J,Rameez MJ,Mondal N,Mapder T,Chatterjee S,Pyne P,Alam M,Haldar PK,Roy R,Fernandes S,Peketi A,Chakraborty R,Mazumdar A,Ghosh W

    更新日期:2020-10-16 00:00:00

  • Isolation and characterization of a Staphylococcus warneri strain producing an anti-Legionella peptide.

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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Héchard Y,Ferraz S,Bruneteau E,Steinert M,Berjeaud JM

    更新日期:2005-11-01 00:00:00

  • Inhibition of Neurospora crassa cytosolic chitinase by allosamidin.

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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: McNab R,Glover LA

    更新日期:1991-07-15 00:00:00

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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Sangari FJ,García-Lobo JM,Agüero J

    更新日期:1994-09-01 00:00:00

  • Use of lectins for a comparative study of cell wall composition of different anaerobic rumen fungal strains.

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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Guillot J,Breton A,Damez M,Dusser M,Gaillard-Martinie B,Millet L

    更新日期:1990-01-15 00:00:00

  • Cloning, heterologous expression, and sequencing of the Proteus vulgaris glnAntrBC operon and implications of nitrogen control on heterologous urease expression.

    abstract::The glnAntrBC operon of Proteus vulgaris was cloned and heterologously expressed in Escherichia coli. The nucleotide sequence was determined. An open reading frame of 1407 bp was identified as the glnA gene and the deduced amino acid sequence showed 82% identity with the E. coli glutamine synthetase protein. Heterolog...

    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Steglitz-Mörsdorf U,Mörsdorf G,Kaltwasser H

    更新日期:1993-01-15 00:00:00

  • XaxAB-like binary toxin from Photorhabdus luminescens exhibits both insecticidal activity and cytotoxicity.

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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Zhang X,Hu X,Li Y,Ding X,Yang Q,Sun Y,Yu Z,Xia L,Hu S

    更新日期:2014-01-01 00:00:00

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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Park JM,Jang YS,Kim TY,Lee SY

    更新日期:2010-08-01 00:00:00

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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Cateau E,Verdon J,Fernandez B,Hechard Y,Rodier MH

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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


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    pub_type: 杂志文章


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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Okazaki T,Hirai K

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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


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    更新日期:2020-05-01 00:00:00

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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


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    更新日期:2008-07-01 00:00:00

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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: Palhano FL,Orlando MT,Fernandes PM

    更新日期:2004-04-01 00:00:00

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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: McClarty G,Fan H,Andersen AA

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    journal_title:FEMS microbiology letters

    pub_type: 杂志文章


    authors: MacCormick CA,Griffin HG,Gasson MJ

    更新日期:1995-03-15 00:00:00