The deuterium/hydrogen distribution in chondritic organic matter attests to early ionizing irradiation.

abstract：:While admixed populations offer a unique opportunity to detect selection, the admixture in most of the studied populations occurred too recently to produce conclusive signals. By contrast, Malagasy populations originate from admixture between Asian and African populations that occurred ~27 generations ago, providing p...

journal_title：Nature communications

authors： Pierron D,Heiske M,Razafindrazaka H,Pereda-Loth V,Sanchez J,Alva O,Arachiche A,Boland A,Olaso R,Deleuze JF,Ricaut FX,Rakotoarisoa JA,Radimilahy C,Stoneking M,Letellier T

更新日期：2018-03-02 00:00:00

abstract：:One of the main reasons why nonlinear-optical signal processing (regeneration, logic, etc.) has not yet become a practical alternative to electronic processing is that the all-optical elements with nonlinear input-output relationship have remained inherently single-channel devices (just like their electronic counterpa...

journal_title：Nature communications

authors： Li L,Patki PG,Kwon YB,Stelmakh V,Campbell BD,Annamalai M,Lakoba TI,Vasilyev M

更新日期：2017-10-12 00:00:00

abstract：:Detection of microbial components such as lipopolysaccharide (LPS) by Toll-like receptor 4 (TLR4) on macrophages induces a robust pro-inflammatory response that is dependent on metabolic reprogramming. These innate metabolic changes have been compared to aerobic glycolysis in tumour cells. However, the mechanisms by w...

journal_title：Nature communications

authors： Balic JJ,Albargy H,Luu K,Kirby FJ,Jayasekara WSN,Mansell F,Garama DJ,De Nardo D,Baschuk N,Louis C,Humphries F,Fitzgerald K,Latz E,Gough DJ,Mansell A

更新日期：2020-07-30 00:00:00

abstract：:Translationally controlled tumour protein (TCTP) is implicated in growth regulation and cancer. Recently, human TCTP has been suggested to play a role in the DNA damage response by forming a complex with ataxia telangiectasia-mutated (ATM) kinase . However, the exact nature of this interaction and its roles in vivo re...

journal_title：Nature communications

authors： Hong ST,Choi KW

更新日期：2013-01-01 00:00:00

abstract：:Compared with noble metals, semiconductors with surface plasmon resonance effect are another type of SERS substrate materials. The main obstacles so far are that the semiconducting materials are often unstable and easy to be further oxidized or decomposed by laser irradiating or contacting with corrosive substances. H...

journal_title：Nature communications

authors： Zhang Q,Li X,Ma Q,Zhang Q,Bai H,Yi W,Liu J,Han J,Xi G

更新日期：2017-04-24 00:00:00

abstract：:Cancer is caused by the accumulation of multiple genetic mutations, but their cooperative effects are poorly understood. Using a genome-wide analysis of all the somatic mutations in colorectal cancer patients in a large-scale molecular interaction network, here we find that a giant cluster of mutation-propagating modu...

journal_title：Nature communications

authors： Shin D,Lee J,Gong JR,Cho KH

更新日期：2017-11-02 00:00:00

abstract：:Because the surface-to-volume ratio of quasi-two-dimensional materials is extremely high, understanding their surface characteristics is crucial for practically controlling their intrinsic properties and fabricating p-type and n-type layered semiconductors. Van der Waals crystals are expected to have an inert surface ...

journal_title：Nature communications

authors： Siao MD,Shen WC,Chen RS,Chang ZW,Shih MC,Chiu YP,Cheng CM

更新日期：2018-04-12 00:00:00

abstract：:The original version of this Article contained errors in Figures 1 and 3. In Fig. 1b, the label 'IP-PBP3' above the second of the three blots incorrectly read 'IP-PBP1B'. In Fig. 3b, the label 'PBP1B' under the first bar of each chart incorrectly read 'PBP1A'. These errors have been corrected in both the PDF and HTML ...

journal_title：Nature communications

authors： Pazos M,Peters K,Casanova M,Palacios P,VanNieuwenhze M,Breukink E,Vicente M,Vollmer W

更新日期：2019-01-30 00:00:00

abstract：:Understanding the role of intermolecular interaction on through-space charge transfer characteristics in π-stacked molecular systems is central to the rational design of electronic materials. However, a quantitative study of charge transfer in such systems is often difficult because of poor control over molecular morp...

journal_title：Nature communications

authors： Batra A,Kladnik G,Vázquez H,Meisner JS,Floreano L,Nuckolls C,Cvetko D,Morgante A,Venkataraman L

更新日期：2012-01-01 00:00:00

abstract：:Post-transcriptional regulation of cellular mRNA is essential for protein synthesis. Here we describe the importance of mRNA translational repression and mRNA subcellular location for protein expression during B lymphocyte activation and the DNA damage response. Cytoplasmic RNA granules are formed upon cell activation...

journal_title：Nature communications

authors： Díaz-Muñoz MD,Kiselev VY,Le Novère N,Curk T,Ule J,Turner M

更新日期：2017-09-13 00:00:00

abstract：:Fluorescence imaging is one of the most versatile and widely used visualization methods in biomedical research. However, tissue autofluorescence is a major obstacle confounding interpretation of in vivo fluorescence images. The unusually long emission lifetime (5-13 μs) of photoluminescent porous silicon nanoparticles...

journal_title：Nature communications

authors： Gu L,Hall DJ,Qin Z,Anglin E,Joo J,Mooney DJ,Howell SB,Sailor MJ

更新日期：2013-01-01 00:00:00

abstract：:Neurons communicate through chemical synapses and electrical synapses (gap junctions). Although these two types of synapses often coexist between neurons, little is known about whether they interact, and whether any interactions between them are important to controlling synaptic strength and circuit functions. By stud...

journal_title：Nature communications

authors： Liu P,Chen B,Mailler R,Wang ZW

更新日期：2017-03-20 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Panhans M,Hutsch S,Benduhn J,Schellhammer KS,Nikolis VC,Vangerven T,Vandewal K,Ortmann F

更新日期：2020-04-22 00:00:00

abstract：:Over the recent decades there has been tremendous progress in understanding and controlling friction between surfaces in relative motion. However the complex nature of the involved processes has forced most of this work to be of rather empirical nature. Two very distinctive physical systems, hard two-dimensional layer...

journal_title：Nature communications

authors： Vanossi A,Bechinger C,Urbakh M

更新日期：2020-09-16 00:00:00

abstract：:The 'phonon-glass electron-crystal' concept has triggered most of the progress that has been achieved in inorganic thermoelectrics in the past two decades. Organic thermoelectric materials, unlike their inorganic counterparts, exhibit molecular diversity, flexible mechanical properties and easy fabrication, and are mo...

journal_title：Nature communications

authors： Liu J,van der Zee B,Alessandri R,Sami S,Dong J,Nugraha MI,Barker AJ,Rousseva S,Qiu L,Qiu X,Klasen N,Chiechi RC,Baran D,Caironi M,Anthopoulos TD,Portale G,Havenith RWA,Marrink SJ,Hummelen JC,Koster LJA

更新日期：2020-11-10 00:00:00

abstract：:The three-dimensional structure of chromosomes plays an important role in gene expression regulation and also influences the repair of radiation-induced DNA damage. Genomic aberrations that disrupt chromosome spatial domains can lead to diseases including cancer, but how the 3D genome structure responds to DNA damage ...

journal_title：Nature communications

authors： Sanders JT,Freeman TF,Xu Y,Golloshi R,Stallard MA,Hill AM,San Martin R,Balajee AS,McCord RP

更新日期：2020-12-02 00:00:00

abstract：:Amyloid aggregation of α-synuclein (α-syn) is closely associated with Parkinson's disease (PD) and other synucleinopathies. Several single amino-acid mutations (e.g. E46K) of α-syn have been identified causative to the early onset of familial PD. Here, we report the cryo-EM structure of an α-syn fibril formed by N-ter...

journal_title：Nature communications

authors： Zhao K,Li Y,Liu Z,Long H,Zhao C,Luo F,Sun Y,Tao Y,Su XD,Li D,Li X,Liu C

更新日期：2020-05-26 00:00:00

abstract：:Replication-Factor-C (RFC) and RFC-like complexes (RLCs) mediate chromatin engagement of the proliferating cell nuclear antigen (PCNA). It remains controversial how RFC and RLCs cooperate to regulate PCNA loading and unloading. Here, we show the distinct PCNA loading or unloading activity of each clamp loader. ATAD5-R...

journal_title：Nature communications

authors： Kang MS,Ryu E,Lee SW,Park J,Ha NY,Ra JS,Kim YJ,Kim J,Abdel-Rahman M,Park SH,Lee KY,Kim H,Kang S,Myung K

更新日期：2019-06-03 00:00:00

abstract：:Scattering-type scanning near-field optical microscopy (s-SNOM) allows spectroscopic imaging with spatial resolution below the diffraction limit. With suitable light sources, s-SNOM is instrumental in numerous discoveries at the nanoscale. So far, the light sources have been limited to continuous wave or high-repetiti...

journal_title：Nature communications

authors： Wang H,Wang L,Xu XG

更新日期：2016-10-17 00:00:00

abstract：:A longstanding goal of synthetic biology has been the programmable control of cellular functions. Central to this is the creation of versatile regulatory toolsets that allow for programmable control of gene expression. Of the many regulatory molecules available, RNA regulators offer the intriguing possibility of de no...

journal_title：Nature communications

authors： Chappell J,Westbrook A,Verosloff M,Lucks JB

更新日期：2017-10-19 00:00:00

abstract：:It is generally assumed that cells interrogate the mechanical properties of their environment by pushing and pulling on the extracellular matrix (ECM). For instance, acto-myosin-dependent contraction forces exerted at focal adhesions (FAs) allow the cell to actively probe substrate elasticity. Here, we report that a s...

journal_title：Nature communications

authors： Baschieri F,Dayot S,Elkhatib N,Ly N,Capmany A,Schauer K,Betz T,Vignjevic DM,Poincloux R,Montagnac G

更新日期：2018-09-20 00:00:00

abstract：:Denervation of skeletal muscles induces severe muscle atrophy, which is preceded by cellular alterations such as increased plasma membrane permeability, reduced resting membrane potential and accelerated protein catabolism. The factors that induce these changes remain unknown. Conversely, functional recovery following...

journal_title：Nature communications

authors： Cisterna BA,Vargas AA,Puebla C,Fernández P,Escamilla R,Lagos CF,Matus MF,Vilos C,Cea LA,Barnafi E,Gaete H,Escobar DF,Cardozo CP,Sáez JC

更新日期：2020-02-26 00:00:00

abstract：:The Clp protease complex degrades a multitude of substrates, which are engaged by a AAA+ chaperone such as ClpX and subsequently digested by the dynamic, barrel-shaped ClpP protease. Acyldepsipeptides (ADEPs) are natural product-derived antibiotics that activate ClpP for chaperone-independent protein digestion. Here w...

journal_title：Nature communications

authors： Gersch M,Famulla K,Dahmen M,Göbl C,Malik I,Richter K,Korotkov VS,Sass P,Rübsamen-Schaeff H,Madl T,Brötz-Oesterhelt H,Sieber SA

更新日期：2015-02-19 00:00:00

abstract：:Scalable quantum networking requires quantum systems with quantum processing capabilities. Solid state spin systems with reliable spin-optical interfaces are a leading hardware in this regard. However, available systems suffer from large electron-phonon interaction or fast spin dephasing. Here, we demonstrate that the...

journal_title：Nature communications

authors： Nagy R,Niethammer M,Widmann M,Chen YC,Udvarhelyi P,Bonato C,Hassan JU,Karhu R,Ivanov IG,Son NT,Maze JR,Ohshima T,Soykal ÖO,Gali Á,Lee SY,Kaiser F,Wrachtrup J

更新日期：2019-04-26 00:00:00

abstract：:Causal reasoning can shed new light on the major challenges in machine learning for medical imaging: scarcity of high-quality annotated data and mismatch between the development dataset and the target environment. A causal perspective on these issues allows decisions about data collection, annotation, preprocessing, a...

journal_title：Nature communications

authors： Castro DC,Walker I,Glocker B

更新日期：2020-07-22 00:00:00

abstract：:The spin of a single electron in a semiconductor quantum dot provides a well-controlled and long-lived qubit implementation. The electron charge in turn allows control of the position of individual electrons in a quantum dot array, and enables charge sensors to probe the charge configuration. Here we show that the Cou...

journal_title：Nature communications

authors： van Diepen CJ,Hsiao TK,Mukhopadhyay U,Reichl C,Wegscheider W,Vandersypen LMK

更新日期：2021-01-04 00:00:00

abstract：:The fields of soft polymers and macromolecular sciences have enjoyed a unique combination of metals and organic frameworks in the name of metallopolymers or organometallic polymers. When metallopolymers carry charged groups, they form a class of metal-containing polyelectrolytes or metallo-polyelectrolytes. This revie...

journal_title：Nature communications

authors： Zhu T,Sha Y,Yan J,Pageni P,Rahman MA,Yan Y,Tang C

更新日期：2018-10-18 00:00:00

abstract：:Combining vapour sensors into arrays is an accepted compromise to mitigate poor selectivity of conventional sensors. Here we show individual nanofabricated sensors that not only selectively detect separate vapours in pristine conditions but also quantify these vapours in mixtures, and when blended with a variable mois...

journal_title：Nature communications

authors： Potyrailo RA,Bonam RK,Hartley JG,Starkey TA,Vukusic P,Vasudev M,Bunning T,Naik RR,Tang Z,Palacios MA,Larsen M,Le Tarte LA,Grande JC,Zhong S,Deng T

更新日期：2015-09-01 00:00:00

abstract：:The yeast Rab5 homologue, Vps21p, is known to be involved both in the vacuolar protein sorting (VPS) pathway from the trans-Golgi network to the vacuole, and in the endocytic pathway from the plasma membrane to the vacuole. However, the intracellular location at which these two pathways converge remains unclear. In ad...

journal_title：Nature communications

authors： Toshima JY,Nishinoaki S,Sato Y,Yamamoto W,Furukawa D,Siekhaus DE,Sawaguchi A,Toshima J

更新日期：2014-03-25 00:00:00

abstract：:Everyone experiences common events differently. This leads to personal memories that presumably provide neural signatures of individual identity when events are reimagined. We present initial evidence that these signatures can be read from brain activity. To do this, we progress beyond previous work that has deployed ...

journal_title：Nature communications

authors： Anderson AJ,McDermott K,Rooks B,Heffner KL,Dodell-Feder D,Lin FV

更新日期：2020-11-20 00:00:00