Comparison of microdissection testicular sperm extraction, conventional testicular sperm extraction, and testicular sperm aspiration for nonobstructive azoospermia: a systematic review and meta-analysis.

Abstract:

OBJECTIVE:To investigate the relative differences in outcomes among microdissection testicular sperm extraction (micro-TESE), conventional testicular sperm extraction (cTESE), and testicular sperm aspiration (TESA) in men with nonobstructive azoospermia. DESIGN:Systematic review and meta-analysis. SETTING:Outpatient academic and private urology clinics. PATIENTS(S):Men with nonobstructive azoospermia. INTERVENTION(S):Micro-TESE, cTESE, or TESA. MAIN OUTCOME MEASURE(S):Sperm retrieval (SR). RESULT(S):Fifteen studies with a total of 1,890 patients were identified. The weighted average age of the patients was 34.4 years, the follicular stimulating hormone level was 20.5 mIU/mL, the T was 373 ng/dL, and the testicular volume was 13.5 mL. In a direct comparison, performance of micro-TESE was 1.5 times more likely (95% confidence interval 1.4-1.6) to result in successful SR as compared with cTESE. Similarly, in a direct comparison, performance of cTESE was 2.0 times more likely (95% confidence interval 1.8-2.2) to result in successful SR as compared with TESA. Because of inconsistent reporting, evaluation of other procedural characteristics and pregnancy outcomes was not possible. CONCLUSION(S):Sperm retrieval was higher for micro-TESE compared with cTESE and for cTESE compared with TESA. Standardization of reported outcomes as well as combining all available SR data would help to further elucidate the SRs of these procedures.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Bernie AM,Mata DA,Ramasamy R,Schlegel PN

doi

10.1016/j.fertnstert.2015.07.1136

subject

Has Abstract

pub_date

2015-11-01 00:00:00

pages

1099-103.e1-3

issue

5

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(15)01647-7

journal_volume

104

pub_type

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    pub_type: 杂志文章

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    更新日期:1976-07-01 00:00:00

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    journal_title:Fertility and sterility

    pub_type: 杂志文章

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    pub_type: 杂志文章

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    journal_title:Fertility and sterility

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    pub_type: 杂志文章

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    pub_type: 杂志文章

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    journal_title:Fertility and sterility

    pub_type: 杂志文章

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    pub_type: 杂志文章

    doi:

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    pub_type: 杂志文章

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    pub_type: 临床试验,杂志文章,多中心研究

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    更新日期:1995-08-01 00:00:00

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    pub_type: 临床试验,杂志文章

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    pub_type: 临床试验,杂志文章

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    更新日期:2014-01-01 00:00:00

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