Acid Tyrode's solution can stimulate parthenogenetic activation of human and mouse oocytes.

Abstract:

:Fresh and aged (24 hours after ovulation) human oocytes and recently ovulated mouse oocytes may be activated by exposure to acidified Tyrode's solution. No activation of either type of human oocyte was observed after exposure to hyaluronidase or pronase, but significant numbers of fresh mouse oocytes were activated after exposure to pronase but not to chymotrypsin. The implications of these results for the manipulation of human and mouse eggs in vitro are discussed.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Johnson MH,Pickering SJ,Braude PR,Vincent C,Cant A,Currie J

doi

10.1016/s0015-0282(16)53279-8

subject

Has Abstract

pub_date

1990-02-01 00:00:00

pages

266-70

issue

2

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(16)53279-8

journal_volume

53

pub_type

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