Hypotonic diuresis following oropharyngeal stimulation with water in humans.

Abstract:

:The role of oropharyngeal mechanisms in body water regulation was studied in 12 human males by measuring urine output and osmolality before and after drinking a very small volume of distilled water (0.15 ml/kg b.w.t.). Hypotonic diuresis was resulted only in the subjects (n = 6) who drank only sufficient water to keep their oropharynx moist continually over a 20 min period but not in those who (n = 6) drank the same volume of water within several seconds. Sham verbal instructions on drinking induced no changes in subjects examined. These results suggest that oropharyngeal afferents alone, and neither gastric afferents nor psychosomatic effects, may account for hypotonic diuresis following water intake in man.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Akaishi T,Shingai T,Miyaoka Y,Homma S

doi

10.1016/0304-3940(89)90792-1

subject

Has Abstract

pub_date

1989-12-15 00:00:00

pages

70-4

issue

1-3

eissn

0304-3940

issn

1872-7972

pii

0304-3940(89)90792-1

journal_volume

107

pub_type

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