L-glutamate specific [3H]kainic acid binding in the rat neostriatum after degeneration of the cortico-striatal pathway.

abstract：:The effect of carbachol on the excitatory synaptic transmission was studied in rat neostriatal neurons using intracellular and whole-cell voltage clamp-recording methods. Depolarizing excitatory postsynaptic potentials (EPSPs) were evoked by cortical stimulation. Superfusion of carbachol (0.01-3 microM) reversibly dec...

journal_title：Neuroscience letters

authors： Hsu KS,Huang CC,Gean PW

更新日期：1995-09-08 00:00:00

abstract：:By using intracellular deposition of horseradish peroxidase (HRP), a method has been designed for combined light and electron microscopic tracing of single fibers and synaptic terminals, belonging to physiologically characterized neurons. This technique has been successfully tested on the axon collateral systems of ca...

journal_title：Neuroscience letters

authors： Cullheim S,Kellerth JO

更新日期：1976-08-01 00:00:00

abstract：:The distribution of cholecystokinin binding sites was studied by receptor autoradiography in the human striatum at midgestation, birth and adulthood. In the adult, cholecystokinin receptors are inhomogeneously distributed with patches of reduced labeling. In the caudate nucleus but not in the putamen these patches mat...

journal_title：Neuroscience letters

authors： Schiffmann SN,Goldman S,Heyman P,De Vuyst M,De Roy G,Vanderhaeghen JJ

更新日期：1992-07-06 00:00:00

abstract：:Silent synapses display no excitatory post-synaptic currents (EPSCs) at resting potentials, but can conduct at depolarized potentials. In the hippocampal CA1 region of young animals, conversion of silent synapses to functional synapses occurs rapidly after pairing post-synaptic depolarization with 1Hz pre-synaptic sti...

journal_title：Neuroscience letters

authors： Kasten MR,Fan Y,Schulz PE

更新日期：2007-04-24 00:00:00

abstract：:The expression of five muscarinic receptor mRNAs (m1, m2, m3, m4, m5) was examined in neostriatum, hippocampus and frontal cortex of 3, 18, and 33 month old rats. Transcripts for ml (3.0 kb), m2 (6.2 kb), m3 (4.5 kb) and m4 (3.3 kb) were detected in all brain regions studied. A 6.0 kb transcript for the m5 muscarinic ...

journal_title：Neuroscience letters

authors： Lee HJ,Clagett-Dame M,Heideman W,Weiler MS

更新日期：1994-06-20 00:00:00

abstract：:Nicotine and smoking have long been proved to play an important role in cognition and memory in the hippocampus. This effect is closely related to the gamma-aminobutyric acid (GABA)ergic system. Previous research has focused on functional and pharmacological aspects of nicotine's modulation activity. In this study, th...

journal_title：Neuroscience letters

authors： Li SP,Park MS,Bahk JY,Kim MO

更新日期：2002-12-13 00:00:00

abstract：:The regional distribution of binding sites labeled by [3H]haloperidol, in the presence of excess spiroperidol, was compared to the regional distribution of receptors labeled by [3H]SCH 23390 and [3H]sulpiride, [3H]SCH 23390 and [3H]sulpiride labeled distinct nuclei, such as the olfactory tubercle, caudate, globus pall...

journal_title：Neuroscience letters

authors： Contreras PC,Quirion R,Gehlert DR,Contreras ML,O'Donohue TL

更新日期：1987-03-31 00:00:00

abstract：:Parkin gene mutations are by far the most common mutations in both familial Parkinson's disease (PD) and sporadic PD. Approximately, 50% of parkin mutations is exon dosage mutations (i.e., deletions and duplications of entire exons). Here, we first established a MLPA assay for quick detection of parkin exon rearrangem...

journal_title：Neuroscience letters

authors： Guo JF,Dong XL,Xu Q,Li N,Yan XX,Xia K,Tang BS

更新日期：2015-09-14 00:00:00

abstract：:Neurologically healthy individuals use sensory feedback to alter future movements by updating internal models of the effector system and environment. For example, when visual feedback about limb movements or auditory feedback about speech movements is experimentally perturbed, the planning of subsequent movements is a...

journal_title：Neuroscience letters

authors： Max L,Maffett DG

更新日期：2015-03-30 00:00:00

abstract：:Rats subjected to forced oral self-administration of morphine solutions without or in combination with two daily i.p. injections of morphine preferred drinking water when this was offered in addition to morphine solutions. The daily intake of morphine during the terminal phase of self-administration of morphine was 50...

journal_title：Neuroscience letters

authors： Jurna I,Baldauf J,Zenz M

更新日期：1992-04-13 00:00:00

abstract：:The present study was undertaken to investigate whether benzodiazepine receptors are involved in either the anticonvulsant activity of phenytoin against supramaximal seizures or maximal threshold seizures induced by electroshock or the neurotoxicity of phenytoin. Ro 15-1788, a benzodiazepine receptor antagonist, rever...

journal_title：Neuroscience letters

authors： Chweh AY,Swinyard EA,Wolf HH

更新日期：1985-06-24 00:00:00

abstract：:The psychophysiological basis of problem size effect in the arithmetical processing of additions and subtractions was studied with event-related brain potentials (ERP). Subjects were presented sequences of seven numbers, and ERPs elicited to the sixth number were analyzed. Two variables were manipulated: operation typ...

journal_title：Neuroscience letters

authors： Núñez-Peña MI,Honrubia-Serrano ML,Escera C

更新日期：2005-01-03 00:00:00

abstract：:A traditional analysis of intra-encephalic auditory evoked potentials does not highlight the dynamical evolution of the auditory 'information' processing in neither time nor space. This work presents a method for tracing such signal evolution throughout the primary auditory pathway in the mesencephalon of adult anesth...

journal_title：Neuroscience letters

authors： Moraes MF,Del Vecchio F,Terra VC,Garcia-Cairasco N

更新日期：2000-04-21 00:00:00

abstract：:There is evidence suggesting that exposure to an abnormal magnetic environment may produce psychophysiological effects related to abnormalities in responses to stress. This may be of relevance for space medicine where astronauts are exposed to a magnetic field different from that exerted by the Earth. Aim of this stud...

journal_title：Neuroscience letters

authors： Del Seppia C,Mezzasalma L,Messerotti M,Cordelli A,Ghione S

更新日期：2006-06-12 00:00:00

abstract：:Advanced glycation end products (AGEs) in the brain were immunohistochemically examined in Alzheimer's disease (AD) and aging using anti-AGE antibody recognizing mainly carboxymethyllysine. AGE positive staining diffusely located in the neuronal perikarya of hippocampus and parahippocampus in AD and aged brains withou...

journal_title：Neuroscience letters

authors： Takedo A,Yasuda T,Miyata T,Mizuno K,Li M,Yoneyama S,Horie K,Maeda K,Sobue G

更新日期：1996-12-27 00:00:00

abstract：:Neuronal recording and neuroimaging studies have shown that the primary motor area (M1) not only participates in motor execution, but is also engaged during movement preparation. The purpose of the present study was to map the distribution of the preparation- and execution-related activity within the contralateral M1 ...

journal_title：Neuroscience letters

authors： Zang Y,Jia F,Weng X,Li E,Cui S,Wang Y,Hazeltine E,Ivry R

更新日期：2003-02-06 00:00:00

abstract：:Alzheimer's disease has become one of the most impacting disorders since world population is rapidly aging. MicroRNA-125b plays a crucial role in many cellular processes and pathologies, but, to date, its role in Alzheimer's disease is controversial. In this study, we demonstrated, for the first time, that the down re...

journal_title：Neuroscience letters

authors： Micheli F,Palermo R,Talora C,Ferretti E,Vacca A,Napolitano M

更新日期：2016-08-26 00:00:00

abstract：:Cigarette smoking is highly addictive and modern genetic research has identified robust genetic influences on nicotine dependence. An important step in translating these genetic findings to clinical practice is identifying the genetic factors affecting smoking cessation in order to enhance current smoking cessation tr...

journal_title：Neuroscience letters

authors： Chen LS,Horton A,Bierut L

更新日期：2018-03-16 00:00:00

abstract：:After systemic administration of the dopamine agonist apomorphine (APO) in common toads Bufo bufo spinosus, the excitatory receptive fields of retinal R2 and R3 ganglion cells doubled their size and the response activities of these neurons to moving visual stimuli were generally increased. Comparable investigations of...

journal_title：Neuroscience letters

authors： Glagow M,Ewert JP

更新日期：1994-05-23 00:00:00

abstract：:The myelin oligodendrocyte glycoprotein (MOG) is a minor CNS myelin-specific protein that is an important candidate autoantigen in multiple sclerosis. We now report that MOG mRNA transcripts are present in the peripheral nervous system of rodents and primates at levels approximately ten-fold lower than in brain as dem...

journal_title：Neuroscience letters

authors： Pagany M,Jagodic M,Schubart A,Pham-Dinh D,Bachelin C,Baron van Evercooren A,Lachapelle F,Olsson T,Linington C

更新日期：2003-10-30 00:00:00

abstract：:A common obstacle in clinical management of pathological pain is the poor response to opioid analgesics. We now report that delta9-tetrahydrocannabinol (delta9-THC)-induced antinociception remained effective in rats with pathological pain. The selective central cannabinoid receptor antagonist SR141716A, but not the ge...

journal_title：Neuroscience letters

authors： Mao J,Price DD,Lu J,Keniston L,Mayer DJ

更新日期：2000-02-11 00:00:00

abstract：:Current diagnosis of Major depressive disorder (MDD) depends on its clinical symptoms, not on the results of any laboratory examinations. Establishing biological markers for diagnosis of MDD is one of the most important problems to be solved in psychiatry practice. MDD patients (n=8) and a healthy control group (n=8) ...

journal_title：Neuroscience letters

authors： Wei K,Xue HL,Guan YH,Zuo CT,Ge JJ,Zhang HY,Liu BJ,Cao YX,Dong JC,Du YJ

更新日期：2016-08-26 00:00:00

abstract：:This article has been withdrawn at the request of the Editor-in-Chief. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal. ...

journal_title：Neuroscience letters

authors： Luo J,Wang Y,Li W,Long L,Cao H

更新日期：2020-06-29 00:00:00

abstract：:The etiology of schizophrenia is unknown, but the pathogenetic process involves organic changes in brain tissue, which may alter the composition of cerebrospinal fluid (CSF). For the present study, CSF was obtained by lumbar puncture from 22 schizophrenic patients and 38 control patients. We have used scanning electro...

journal_title：Neuroscience letters

authors： Wetterberg L,Nybom R,Bratlid T,Fladby T,Olsson B,Wigzell H

更新日期：2002-08-23 00:00:00

abstract：:In rodents the vomeronasal system plays an important role in modulating the hypothalamic control of gonadotropin secretion. It is accepted that the anatomical pathways by which the vomeronasal organ influences the neuroendocrine aspects of the reproductive behavior involves a polysynaptic system, including the accesso...

journal_title：Neuroscience letters

authors： Larriva-Sahd J,Rondán A,Orozco-Estévez H,Sánchez-Robles MR

更新日期：1993-11-26 00:00:00

abstract：:The rodent gustatory cortex is located in the anterior part of the insular cortex, which is near the dorsal part of the rhinal vein (RHV) and the intersection of the anterior and posterior regions of the middle cerebral artery (MCA). Thus, the intersection between the RHV and MCA is used as a landmark for the rodent g...

journal_title：Neuroscience letters

authors： Kida I,Enmi J,Iida H,Yoshioka Y

更新日期：2015-03-04 00:00:00

abstract：:Freshwater clams are a popular health food in Asia and are traditionally used to prevent hepatic inflammation. Freshwater clam extract (FCE) inhibits inflammatory responses in activated macrophages by reducing the activation of mitogen-activated protein kinase and nuclear factor kappa-light-chain-enhancer of activated...

journal_title：Neuroscience letters

authors： Hsieh CC,Lin MS,Hua KF,Chen WJ,Lin CC

更新日期：2017-03-06 00:00:00

abstract：:Enterovirus infections of the central nervous system (CNS) are common and important causes of morbidity in immunocompromised children and adults. In this study we identify and characterize coxsackievirus B4-induced neuronal death. To investigate the CNS pathophysiology resulting from this viral infection, cultured rat...

journal_title：Neuroscience letters

authors： Joo CH,Kim YK,Lee H,Hong H,Yoon SY,Kim D

更新日期：2002-07-05 00:00:00

abstract：:We investigated a possible involvement of the prion protein in ventilatory control in four groups of mice, those deficient for the prion protein (PrP(c)), those overexpressing the prion protein, and two groups of genetically and age-matched controls. Ventilatory patterns of unrestrained mice were measured in a whole-b...

journal_title：Neuroscience letters

authors： Boudinot E,Tremblay P,Champagnat J,Foutz AS

更新日期：2002-04-26 00:00:00

abstract：:Leucine-rich glioma inactivated 3 (LGI3) is a member of LGI/epitempin (EPTP) family. The biological function of LGI3 and its association with disease are not known. We previously reported that mouse LGI3 was highly expressed in brain in a developmentally and transcriptionally regulated manner. In this study, we identi...

journal_title：Neuroscience letters

authors： Park WJ,Lee SE,Kwon NS,Baek KJ,Kim DS,Yun HY

更新日期：2008-10-31 00:00:00