Respiratory function in mice lacking or overexpressing the prion protein.

abstract：:A major goal in the study of motor learning is to improve the extent to which subjects adapt their movements in response to errors. Recent attention has focused on the gradual-adaptation paradigm, in which an adaptive stimulus is introduced incrementally, rather than all at once as in conventional adaptation paradigms...

journal_title：Neuroscience letters

authors： Wong AL,Shelhamer M

更新日期：2011-08-18 00:00:00

abstract：:In membrane physiology, as in other fields, myths or speculations may be repeated so often and so widely that they are perceived as facts. To some extent, this has occurred with regard to gap junctions, hemichannels, pannexin channels and P2X7 (ionotropic receptors), especially concerning the interpretation of the ind...

journal_title：Neuroscience letters

authors： de Freitas PHM,da Silva Ferreira NC,Fioravante-Rezende JG,de Menezes Santos L,Alves LA,Rozental R

更新日期：2019-03-16 00:00:00

abstract：:The magnocellular neurones of the supraoptic nucleus (SON) and paraventricular nucleus release neuropeptide from their axon terminals and also from their dendrites. In the axon terminals, swellings known as Herring bodies are responsible for the degradation of aged, unreleased large dense-cored vesicles (LDCVs) by lys...

journal_title：Neuroscience letters

authors： Monteiro O,Wiegand UK,Ludwig M

更新日期：2011-02-01 00:00:00

abstract：:The axonal efferents of neurons of the supraoptic nucleus area were studied by radioautography in the rat after discrete stereotaxic injections of [3H]leucine into this nucleus. Beside a densely labeled pathway running from the nucleus to the posterior pituitary through the internal median eminence, several of the vis...

journal_title：Neuroscience letters

authors： Alonso G,Szafarczyk A,Assenmacher I

更新日期：1986-05-23 00:00:00

abstract：:Guanidine, the active ingredient extracted from Galega officinalis, is introduced as a ligand for imidazoline I2 receptor (I2R) because guanidine decreased plasma glucose via an activation of I2BR to increase glucose uptake into skeletal muscle isolated from Wistar rats. However, the signals for this action of guanidi...

journal_title：Neuroscience letters

authors： Lui TN,Tsao CW,Huang SY,Chang CH,Cheng JT

更新日期：2010-05-03 00:00:00

abstract：:Neurofibromatosis 1 (NF1) is a common autosomal dominant disorder in which affected individuals develop benign and malignant tumors as well as non-tumor-related abnormalities, such as seizures and learning disabilities. Here, we report an NF1 isoform arising from the alternative splicing of exon 9a with predominant ce...

journal_title：Neuroscience letters

authors： Geist RT,Gutmann DH

更新日期：1996-06-21 00:00:00

abstract：:Gamma-band oscillations are related to sensory information processing and attention. To further illuminate the relationship of gamma-band activity and selective somatic attention, we have studied the effects of direction of attention on the stimuli of somatosensory evoked potentials. Responses during focused attention...

journal_title：Neuroscience letters

authors： Gobbelé R,Waberski TD,Schmitz S,Sturm W,Buchner H

更新日期：2002-07-12 00:00:00

abstract：:Microglia, the resident immune cells of the brain, are activated in response to any kind of CNS injury, and their activation is critical for maintaining homeostasis within the CNS. However, during inflammatory conditions, sustained microglial activation results in damage to surrounding neuronal cells. beta-Glucans are...

journal_title：Neuroscience letters

authors： Shah VB,Williams DL,Keshvara L

更新日期：2009-07-24 00:00:00

abstract：:Imaging and lesion studies suggest that the cerebellum is involved in the self-generation of timed motor responses. Using repetitive transcranial magnetic stimulation (rTMS), we studied the effects of transient disruption of the lateral or medial cerebellum on a paced-finger-tapping task (PFT). Results show greater va...

journal_title：Neuroscience letters

authors： Théoret H,Haque J,Pascual-Leone A

更新日期：2001-06-22 00:00:00

abstract：:We analyzed event-related potential (ERP) correlates of numerical and alphabetical positional judgements. Sixteen subjects classified whether acoustically presented numbers (1, 4, 6 or 9) were smaller or larger than 5 or whether phonemes (a, d, f or i) stood before or after letter 'e' in the alphabet. Stimulus non-spe...

journal_title：Neuroscience letters

authors： Szucs D,Csépe V

更新日期：2004-04-22 00:00:00

abstract：:The goal of this study was to examine the coupling between visual information and body sway with binocular and monocular vision at two distances from the front wall of a moving room. Ten participants stood as still as possible inside of a moving room facing the front wall in conditions that combined room movement with...

journal_title：Neuroscience letters

authors： Moraes R,Lopes AG,Barela JA

更新日期：2009-09-04 00:00:00

abstract：:Neurotrophins are a family of growth factor primarily acting in the nervous system, throughout two categories of membrane receptors on the basis of their high (Trk receptors) or low (p75NTR) affinity. Both neurotrophins and Trk receptors are phylogenetically conserved and are expressed not only in the central and peri...

journal_title：Neuroscience letters

authors： Abbate F,Guerrera MC,Montalbano G,Levanti MB,Germanà GP,Navarra M,Laurà R,Vega JA,Ciriaco E,Germanà A

更新日期：2014-03-20 00:00:00

abstract：:To investigate changes in regional cerebral blood flow (rCBF) under the prone condition with and without light massage on the back, we measured rCBF quantitatively in healthy human subjects using positron emission tomography with H(2)15O. Biochemical tests showed that the light massage (palm-pressure) reduced levels o...

journal_title：Neuroscience letters

authors： Ouchi Y,Kanno T,Okada H,Yoshikawa E,Shinke T,Nagasawa S,Minoda K,Doi H

更新日期：2006-10-23 00:00:00

abstract：:To clarify the possible involvement of protein kinase (PK) C activation in the excitation and sensitization of polymodal receptors (PMRs), the effects of phorbol 12,13-dibutyrate (PDBu) on PMRs were studied in canine testis-spermatic nerve preparations in vitro. Application of PDBu (10(-7), 10(-6), AND 10(-5) M) for 5...

journal_title：Neuroscience letters

authors： Leng S,Mizumura K,Koda H,Kumazawa T

更新日期：1996-03-08 00:00:00

abstract：:With the use of the microdialysis technique, we examined the modulatory effect of ketamine on catecholamine efflux from in vivo cardiac sympathetic nerve endings. A dialysis probe was implanted in the left ventricular myocardium, and dialysate norepinephrine (NE) levels in anesthetized cats were measured with liquid c...

journal_title：Neuroscience letters

authors： Kitagawa H,Yamazaki T,Akiyama T,Yahagi N,Kawada T,Mori H,Sunagawa K

更新日期：2002-05-24 00:00:00

abstract：:The effect of the metabotropic glutamate receptor (mGluR) antagonist (RS)-alpha-methyl-4-carboxyphenylglycine (MCPG) was investigated on the induction of long-term potentiation (LTP) of alpha-amino-3-hydroxy-5- methyl-4-isoxazoleproprionate receptor-mediated excitatory postsynaptic currents (epscs) recorded from denta...

journal_title：Neuroscience letters

authors： Wang Y,Rowan MJ,Anwyl R

更新日期：1995-09-15 00:00:00

abstract：:Nogo-A is an inhibitor of neurite outgrowth and axonal regeneration after CNS injury. Several functional regions including Nogo-66 were identified to mediate the inhibitory effect of Nogo-A. We have reported that Nogo-66 could promote neural progenitors to differentiate into glial cells. Here we exam three other regio...

journal_title：Neuroscience letters

authors： Gao Y,Xiao Z,Chen B,Wang B,Han J,Zhao Y,Zhang J,Dai J

更新日期：2009-07-24 00:00:00

abstract：:The blood-brain barrier (BBB) plays an important role in controlling the passage of molecules from the blood to the extracellular fluid environment of the brain. An immortalised rat brain endothelial cell line (GPNT) was used to investigate the mechanisms underlying dexamethasone-induced decrease in paracellular perme...

journal_title：Neuroscience letters

authors： Romero IA,Radewicz K,Jubin E,Michel CC,Greenwood J,Couraud PO,Adamson P

更新日期：2003-06-26 00:00:00

abstract：:We used the mismatch negativity event-related potential to examine how spatial location and feature variation affect the capacity of the auditory system to automatically respond to pairs of rapid (180 ms apart) acoustic changes within a single tone. When a tone first deviated from a standard tone in source location an...

journal_title：Neuroscience letters

authors： Deouell LY,Karns CM,Harrison TB,Knight RT

更新日期：2003-01-02 00:00:00

abstract：:The fate of neural stem/progenitor cells (NSCs/NPCs) in vivo lies on the local microenvironment. Whether the denervated hippocampus provides a stimulative role on the survival and differentiation of the anterior subventricular zone (SVZa) progenitors was investigated in the present study. In vivo the SVZa progenitors ...

journal_title：Neuroscience letters

authors： Zhang X,Jin G,Tian M,Qin J,Huang Z

更新日期：2007-03-06 00:00:00

abstract：:The interleukin-6 (IL-6) family of cytokines is thought to be involved in the development and regeneration of peripheral nerves; however, their roles in myelination remain unclear. In this study, we examined the effects of IL-6 on the expression of genes for compact myelin proteins using Schwann cell cultures prepared...

journal_title：Neuroscience letters

authors： Ito T,Ikeda K,Tomita K,Yokoyama S

更新日期：2010-03-19 00:00:00

abstract：:Although chlorpromazine was shown to greatly inhibit a Ca2+-mediated cell death at favorable concentrations (10(-6)-10(-5) M), it caused a drastic decrease in cell viability at higher concentrations (10(-4)-10(-3) M) in a human neuroblastoma cell line. The toxic effect of chlorpromazine also occurred in Ca2+-free medi...

journal_title：Neuroscience letters

authors： Abe K,Sekizawa T,Kogure K

更新日期：1986-11-21 00:00:00

abstract：:Accumulating evidence indicates that somatostatin (SS) is a key substance for the circadian rhythm of rodents. In the present study, we investigated whether SS mRNA coexists with arginine-vasopressin (AVP) mRNA, vasoactive intestinal peptide/peptide histidine isoleucine amide (VIP/PHI) mRNA and glutamate decarboxylase...

journal_title：Neuroscience letters

authors： Tanaka M,Okamura H,Matsuda T,Shigeyoshi Y,Hisa Y,Chihara K,Ibata Y

更新日期：1996-09-06 00:00:00

abstract：:Throughout life, new neurons are continuously generated from subventricular zone and added to the olfactory bulb (OB). Because a subset of mature OB neurons undergoes spontaneous cell death, adult OB neurogenesis serves for the replacement of this cell loss. Spontaneous cell turnover should alter the neuronal circuits...

journal_title：Neuroscience letters

authors： Kim WR,Sun W

更新日期：2013-08-26 00:00:00

abstract：:Aromatic L-amino acid decarboxylase (AADC) decarboxylates L-DOPA and 5-hydroxytryptophan into dopamine and serotonin, respectively. Starting from a rat AADC cDNA clone isolated in our laboratory, we produced a beta-galactosidase-AADC fusion protein in E. coli. It was purified from inclusion bodies and injected into a ...

journal_title：Neuroscience letters

authors： Krieger M,Tillet Y,Gros F,Thibault J

更新日期：1993-04-16 00:00:00

abstract：:Projection of the vagal C-afferent to the insular cortex was examined in rats. Electrical activation of the C-afferent resulted in two cortical field potentials in the anterior insula. They were independent of each other and neither of them was attributed to the specific thalamic projection. These results imply that v...

journal_title：Neuroscience letters

authors： Ito S

更新日期：1992-12-14 00:00:00

abstract：:Anterior pharynx-defective 1 (Aph-1) is a multi-spanning membrane protein and an integral component of the high molecular weight gamma-secretase complex that also contains presenilin, nicastrin, and Pen-2. In order to clarify the existence of an endogenous fragment of Aph-1 and dissect the localization and processing ...

journal_title：Neuroscience letters

authors： Sanjo N,Katayama T,Hasegawa H,Jin H,Duthie M,Mount HT,Mizusawa H,St George-Hyslop P,Fraser PE

更新日期：2010-10-08 00:00:00

abstract：:The streptozotocin (STZ)-induced diabetes model is widely used for the induction of neuropathy in the rat. In this model, diabetic animals often display chronic illness, which raises objections not only on ethical but also on scientific grounds. In this study, the investigators set out to determine the impact of bodyw...

journal_title：Neuroscience letters

authors： Hoybergs YM,Biermans RL,Meert TF

更新日期：2008-05-02 00:00:00

abstract：:The myelin oligodendrocyte glycoprotein (MOG) is a minor CNS myelin-specific protein that is an important candidate autoantigen in multiple sclerosis. We now report that MOG mRNA transcripts are present in the peripheral nervous system of rodents and primates at levels approximately ten-fold lower than in brain as dem...

journal_title：Neuroscience letters

authors： Pagany M,Jagodic M,Schubart A,Pham-Dinh D,Bachelin C,Baron van Evercooren A,Lachapelle F,Olsson T,Linington C

更新日期：2003-10-30 00:00:00

abstract：:The opioid peptide dynorphin A(1-8) (1 micron) increased acetylcholine release from the Torpedo electric organ by approximately twofold. This effect was reversed by the opiate antagonist naloxone. The effect of Dyn A(1-8) on acetylcholine release was found to vary in magnitude with the seasons of the year, with maxima...

journal_title：Neuroscience letters

authors： Oron L,Sarne Y,Michaelson DM

更新日期：1991-04-29 00:00:00