Cytochemical evidence for an inhomogeneous distribution of sodium channels in the squid giant axon.

abstract：:The human hypothalamus is at the center of the human limbic system anatomically and physiologically. The hypothalamus plays pivotal roles in controlling autonomic responses and instinctive behaviors such as regulating fear, aggression, learning, feeding behavior, circadian rhythm, and reproductive activities. The deta...

journal_title：Neuroscience letters

authors： Kamali A,Ghazi Sherbaf F,Rahmani F,Khayat-Khoei M,Aein A,Gandhi A,Shah EG,Sair HI,Riascos RF,Esquenazi Y,Zhu JJ,Keser Z,Hasan KM

更新日期：2020-05-29 00:00:00

abstract：:A new non-N-methyl-D-aspartate (non-NMDA) glutamate receptor antagonist, GYKI 52466, was tested on L-glutamate (Glu)-, kainate (KAI)- and NMDA-induced responses in vivo, using both extracellular recording of antidromic field potentials and intracellular recording from rat abducens motoneurones. Intravenous (5-10 mg/kg...

journal_title：Neuroscience letters

authors： Ouardouz M,Durand J

更新日期：1991-04-15 00:00:00

abstract：:Deep brain stimulation (DBS) is associated with substantial improvements in motor symptoms of PD. Emerging evidence has suggested that nonlinear measures of complexity may provide greater insight into the efficacy of anti-PD treatments. This study investigated sample entropy and complexity index values in individuals ...

journal_title：Neuroscience letters

authors： Powell DW,Blackmore SE,Puppa M,Lester D,Murray NG,Reed-Jones RJ,Xia RP

更新日期：2020-05-29 00:00:00

abstract：:Substantial evidence supports the hypothesis that oxygen free radicals are involved in various neurodegenerative disorders. To assess the presence of oxidative stress in Alzheimer's disease (AD) we examined the activity of the enzyme copper-zinc superoxide dismutase (CuZnSOD) in red blood cells, the levels of the mito...

journal_title：Neuroscience letters

authors： De Leo ME,Borrello S,Passantino M,Palazzotti B,Mordente A,Daniele A,Filippini V,Galeotti T,Masullo C

更新日期：1998-07-10 00:00:00

abstract：:Modulation of ionic channel properties by neurotransmitters and hormones is called neuromodulation and may be the basis for many long-lasting changes in animal behavior, e.g. changes in the arousal or motivational states. Gonadotropin-releasing hormone (GnRH), originally identified as a hypophysiotropic hormone, is no...

journal_title：Neuroscience letters

authors： Oka Y

更新日期：1992-08-17 00:00:00

abstract：:Sleep fragmentation due to intermittent nocturnal arousal resulting in a reduction of total sleep time and sleep efficiency is a common symptom among people with Alzheimer's disease (AD) and elderly people with normal cognitive function. Although epidemiological studies have indicated an association between sleep frag...

journal_title：Neuroscience letters

authors： Minakawa EN,Miyazaki K,Maruo K,Yagihara H,Fujita H,Wada K,Nagai Y

更新日期：2017-07-13 00:00:00

abstract：:Cerebellar Purkinje cells differentiate the most elaborate dendritic trees among neurons in the brain and constitute the principal part of cerebellar neuronal circuitry. In the present study, we examined the role of the GluA2 subunit of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate recepto...

journal_title：Neuroscience letters

authors： Tanaka M,Senda T,Hirashima N

更新日期：2017-09-14 00:00:00

abstract：:Two types of mRNAs for neurofibromin isoforms, which are produced by Von Recklinghausen neurofibromatosis (NF1) gene, have so far been identified. In the present study, we analyzed the differential expression of the two NF1 mRNAs in 16 cases of human astrocytic tumors and in surrounding normal tissues by the RNA-polym...

journal_title：Neuroscience letters

authors： Tokuyama T,Uemura K,Fujita M

更新日期：1995-08-25 00:00:00

abstract：:Large-conductance calcium-activated potassium channels (BK channels) have been suggested to play a substantial role in synaptic transmission in the spinal cord dorsal horn. In the present experiments, we attempted to clarify the physiological significance of BK channels in the modulation of synaptic transmission in th...

journal_title：Neuroscience letters

authors： Furukawa N,Takasusuki T,Fukushima T,Hori Y

更新日期：2008-10-17 00:00:00

abstract：:Previous tracer studies have revealed the sacculus to be connected to the vestibular and cochlear nuclei in the guinea pig. Due to its own innervation pattern, an anterior and posterior part of the sacculus can be distinguished. The present study investigated whether the two parts differ concerning their fiber contrib...

journal_title：Neuroscience letters

authors： Gstoettner W,Burian M,Zundritsch R,Mayr R

更新日期：1991-01-28 00:00:00

abstract：:The commonly used benzidine derivatives such as diaminobenzidine, o-dianisidine and benzidine dihydrochloride are apparently carcinogenic. Available information, however, indicates that tetramethyl benzidine (TMB) is safer in this regard, and we have therefore developed a procedure in which TMB is used as a substrate ...

journal_title：Neuroscience letters

authors： Hardy H,Heimer L

更新日期：1977-08-01 00:00:00

abstract：:Repetitive transcranial magnetic stimulation (rTMS) is a promising method for use in the clinical field, as it can induce modulation of cortical excitability. Generally, rTMS inhibits the motor cortex when delivered at less than 1 Hz. However, it has been indicated that a facilitative effect is induced by 1 Hz rTMS, d...

journal_title：Neuroscience letters

authors： Nojima K,Iramina K

更新日期：2018-01-18 00:00:00

abstract：:In guinea pig hippocampal slices, 4-aminopyridine (4-AP) in concentrations of 100-500 microM reduced the adaptation of CA3 pyramidal neurons to depolarizing stimuli, resulting in a prolongation of repetitive firing during injection of long-lasting depolarizing currents. Concurrently, there was a decrease in the 'sag' ...

journal_title：Neuroscience letters

authors： Matsuda Y,Yoshida S,Fujimura K,Nakamura M

更新日期：1986-04-24 00:00:00

abstract：:Our previous studies have shown that acupuncture attenuates morphine self-administration and sensitization behavior as well as withdrawal signs. The present study was designed to investigate the role of acupuncture in the reinstatement of morphine seeking. Male Sprague-Dawley rats weighing 270-300 g were subjected to ...

journal_title：Neuroscience letters

authors： Lee BH,Ma JH,In S,Kim HY,Yoon SS,Jang EY,Yang CH

更新日期：2012-10-31 00:00:00

abstract：:Nerve growth factor (NGF) was injected in the brain of neonatal rats. In eleven of thirty-one rats that received 1 microgram of mouse NGF (2.5S form) on postnatal day 3, NGF receptor-like immunoreactivity was found in the preoptic area (POA) and hypothalamus until 12 days after birth. However, no immunoreactivity was ...

journal_title：Neuroscience letters

authors： Nishizuka M,Arai Y

更新日期：1992-04-27 00:00:00

abstract：:For the fast and accurate cognition of external information, the human brain seems to integrate information from multi-sensory modalities. We used positron emission tomography (PET) to identify the brain areas related to auditory-visual speech perception. We measured the regional cerebral blood flow (rCBF) of young, n...

journal_title：Neuroscience letters

authors： Kawase T,Yamaguchi K,Ogawa T,Suzuki K,Suzuki M,Itoh M,Kobayashi T,Fujii T

更新日期：2005-07-15 00:00:00

abstract：:Recently, a series of both non-coding (intronic) and coding (exonic) mutations in the tau gene have been linked to a family of autosomal dominant dementias referred to as frontotemporal dementia-17. While linkage analysis has demonstrated that these mutations segregate with disease in affected families, it is unclear ...

journal_title：Neuroscience letters

authors： Jicha GA,Rockwood JM,Berenfeld B,Hutton M,Davies P

更新日期：1999-02-05 00:00:00

abstract：:A previous study of brain activation in normal subjects during a phonological (Phonemes) task and a lexical semantic (Words) task using positron-emission tomography [3] is complemented by new data after a method for image realignment was applied [17]. The pattern of cerebral blood flow increases associated with Words ...

journal_title：Neuroscience letters

authors： Démonet JF,Price C,Wise R,Frackowiak RS

更新日期：1994-11-21 00:00:00

abstract：:The purpose of this study was to characterize the neuromuscular control during shortening (SHO) and lengthening (LEN) contractions by investigating the input-output (I/O) property in the corticospinal tract. To this end, the relation between various stimulus intensities applied via transcranial magnetic stimulation an...

journal_title：Neuroscience letters

authors： Sekiguchi H,Kimura T,Yamanaka K,Nakazawa K

更新日期：2001-10-19 00:00:00

abstract：:Several studies have indicated that higher levels of childhood aerobic fitness is associated with superior cognitive function, and this association is disproportionately observed in tasks requiring greater top-down control. We designed the current study to clarify the relationship between childhood fitness and top-dow...

journal_title：Neuroscience letters

authors： Kamijo K,Takeda Y,Takai Y,Haramura M

更新日期：2016-10-06 00:00:00

abstract：:Cyclosporine A (CsA) is the major immunosuppressive drug used for organ and neural transplantation and the therapy of selected autoimmune diseases. We investigated the effect of CsA on the activity of acetylcholinesterase (AChE) in the frontal cortex, hippocampus, septum, and basal ganglia. AChE was determined spectro...

journal_title：Neuroscience letters

authors： Herink J,Krejcová G,Bajgar J,Svoboda Z,Kvĕtina J,Zivnú P,Palicka V

更新日期：2003-03-27 00:00:00

abstract：:The standard pseudohomophone effect in the lexical decision task, i.e. longer response times and higher error rates for pseudohomophones compared with spelling controls, is commonly explained by an orthography-phonology-conflict. This study tested this conflict account, using a multi-method approach including particip...

journal_title：Neuroscience letters

authors： Briesemeister BB,Hofmann MJ,Tamm S,Kuchinke L,Braun M,Jacobs AM

更新日期：2009-05-15 00:00:00

abstract：:Effects of conceptual fusion on episodic associative retrieval were examined. Subjects attempted to fuse sequentially displayed (800 ms offset) word pairs; pairs subjects were unable to fuse were instead considered associated by juxtaposition. Next, dense-array event-related potentials (ERPs) were recorded while the p...

journal_title：Neuroscience letters

authors： Kounios J,Bachman P,Casasanto D,Grossman M,Smith RW,Yang W

更新日期：2003-07-24 00:00:00

abstract：:Apoptotic cell death is associated with condensation and fragmentation of the nuclear chromatin into apoptotic bodies. Such nuclei occur frequently following cerebral hypoxia-ischemia in 1 week old rats but seem sparse in older animals. We investigated the age dependence by counting pyknotic or punctate chromatin cont...

journal_title：Neuroscience letters

authors： Sidhu RS,Tuor UI,Del Bigio MR

更新日期：1997-02-21 00:00:00

abstract：:Cerebrospinal fluid concentration of nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin-3 (NT-3) was measured in normal developing rat from birth to postnatal day (PND) 21 by enzyme-linked immunosorbent assay. NGF levels were significantly higher than those of BDNF and NT-3 from PND ...

journal_title：Neuroscience letters

authors： Xia YX,Ikeda T,Xia XY,Ikenoue T

更新日期：2000-02-25 00:00:00

abstract：:Insulin-like growth factor binding protein (IGFBP) 7 may be a critical regulator of memory consolidation. This study was performed to assess the relationship between circulating IGFBP7 levels and postoperative cognition dysfunction (POCD) in patients scheduled for elective head and neck carcinoma surgery under general...

journal_title：Neuroscience letters

authors： Jiang J,Chen Z,Liang B,Yan J,Zhang Y,Xu H,Huang Y,Jiang H

更新日期：2015-02-19 00:00:00

abstract：:The present study was performed to explore the role of galanin in nociceptive modulation in anterior cingulate cortex (ACC) of rats with acute inflammation, and the changes in galanin and galanin receptor 2 (Gal R2) expressions in rats with acute inflammation. Intra-ACC injection of galanin induced antinociception in ...

journal_title：Neuroscience letters

authors： Zhang ML,Fu FH,Yu LC

更新日期：2017-01-18 00:00:00

abstract：:Generation of free radicals and subsequent lipid peroxidation have been proposed to contribute to delayed tissue damage following traumatic spinal cord injury (SCI). Ubiquinols (reduced coenzyme Q), ascorbate (vitamin C), and alpha-tocopherol (vitamin E) are endogenous antioxidants; decreases in tissue levels of these...

journal_title：Neuroscience letters

authors： Lemke M,Frei B,Ames BN,Faden AI

更新日期：1990-01-01 00:00:00

abstract：:Previous studies have showed that SIN-1, a nitric oxide (NO) donor, injected into the dorsolateral column of the periaqueductal gray (dlPAG) induces flight reactions. This drug, however, can also produce peroxynitrite, which may interfere in this effect. In addition, it is also unknown if this effect is mediated by lo...

journal_title：Neuroscience letters

authors： Braga AA,Aguiar DC,Guimarães FS

更新日期：2009-08-07 00:00:00

abstract：:Following the i.c.v. administration of antivasopressin serum the alpha-MPT-induced disappearance of noradrenaline was decreased in the dorsal septal nucleus, parafascicular nucleus and the rostral part of the nucleus tractus solitarii, whereas that of dopamine was lowered in the caudate nucleus and in the A2 region of...

journal_title：Neuroscience letters

authors： Versteeg DH,De Kloet ER,Greidanus TV,De Wied D

更新日期：1979-01-01 00:00:00