Gut-spilling in chordates: evisceration in the tropical ascidian Polycarpa mytiligera.

abstract：:Although the use of metabarcoding to identify taxa in DNA mixtures is widely approved, its reliability in quantifying taxon abundance is still the subject of debate. In this study we investigated the relationships between the amount of pollen grains in mock solutions and the abundance of high-throughput sequence reads...

journal_title：Scientific reports

authors： Baksay S,Pornon A,Burrus M,Mariette J,Andalo C,Escaravage N

更新日期：2020-03-06 00:00:00

abstract：:Outer membrane vesicles (OMVs) produced by Gram-negative bacteria have roles in cell-to-cell signaling, biofilm formation, and stress responses. Here, the effects of abiotic stressors on OMV contents and composition from biofilm cells of the plant health-promoting bacterium Pseudomonas chlororaphis O6 (PcO6) are exami...

journal_title：Scientific reports

authors： Potter M,Hanson C,Anderson AJ,Vargis E,Britt DW

更新日期：2020-12-04 00:00:00

abstract：:Discovery of novel biomarkers is critical for early diagnosis of acute coronary syndrome (ACS). Serum metabolite profiling of ST-elevation myocardial infarction (STEMI), unstable angina (UA) and healthy controls was performed using gas chromatography mass spectrometry (GC/MS), solid-phase microextraction coupled to ga...

journal_title：Scientific reports

authors： Ali SE,Farag MA,Holvoet P,Hanafi RS,Gad MZ

更新日期：2016-11-08 00:00:00

abstract：:Huntington's disease (HD) is a progressive, dominantly inherited neurological disorder caused by an abnormal expansion of polyglutamine (polyQ) repeat within the Huntingtin (Htt) protein with no disease modifying treatments. In a Drosophila model of HD, expression of mutant Huntingtin (Htt) protein with expanded polyQ...

journal_title：Scientific reports

authors： Chongtham A,Agrawal N

更新日期：2016-01-05 00:00:00

abstract：:Autism spectrum disorder (ASD) is a continuum of neurodevelopmental disorders and needs new therapeutic approaches. Recently, oxytocin (OXT) showed potential as the first anti-ASD drug. Many reports have described the efficacy of intranasal OXT therapy to improve the core symptoms of patients with ASD; however, the un...

journal_title：Scientific reports

authors： Horiai M,Otsuka A,Hidema S,Hiraoka Y,Hayashi R,Miyazaki S,Furuse T,Mizukami H,Teruyama R,Tamura M,Bito H,Maejima Y,Shimomura K,Nishimori K

更新日期：2020-12-17 00:00:00

abstract：:Krüppel-like factor 6 (KLF6) is a transcription factor and tumor suppressor. We previously identified KLF6 as mediator of hepatocyte glucose and lipid homeostasis. The loss or reduction of KLF6 is linked to the progression of hepatocellular carcinoma, but its contribution to liver regeneration and repair in acute live...

journal_title：Scientific reports

authors： Sydor S,Manka P,Best J,Jafoui S,Sowa JP,Zoubek ME,Hernandez-Gea V,Cubero FJ,Kälsch J,Vetter D,Fiel MI,Hoshida Y,Bian CB,Nelson LJ,Moshage H,Faber KN,Paul A,Baba HA,Gerken G,Friedman SL,Canbay A,Bechmann LP

更新日期：2017-08-14 00:00:00

abstract：:Oral microbiome dysbiosis has been associated with various local and systemic human diseases such as dental caries, periodontal disease, obesity, and cardiovascular disease. Bacterial composition may be affected by age, oral health, diet, and geography, although information about the natural variation found in the gen...

journal_title：Scientific reports

authors： Burcham ZM,Garneau NL,Comstock SS,Tucker RM,Knight R,Metcalf JL,Genetics of Taste Lab Citizen Scientists.

更新日期：2020-02-07 00:00:00

abstract：:Thiamine monophosphate kinase (ThiL) catalyzes the last step of thiamine pyrophosphate (TPP) synthesis, the ATP-dependent phosphorylation of thiamine monophosphate (TMP) to thiamine pyrophosphate. We solved the structure of ThiL from the human pathogen A. baumanii in complex with a pair of substrates TMP and a non-hyd...

journal_title：Scientific reports

authors： Sullivan AH,Dranow DM,Horanyi PS,Lorimer DD,Edwards TE,Abendroth J

更新日期：2019-03-13 00:00:00

abstract：:The cancer stem cell (CSC) hypothesis proposes a hierarchical organization of tumors, in which stem-like cells sustain tumors and drive metastasis. The molecular mechanisms underlying the acquisition of CSCs and metastatic traits are not well understood. SOX9 is a transcription factor linked to stem cell maintenance a...

journal_title：Scientific reports

authors： Carrasco-Garcia E,Lopez L,Aldaz P,Arevalo S,Aldaregia J,Egaña L,Bujanda L,Cheung M,Sampron N,Garcia I,Matheu A

更新日期：2016-08-30 00:00:00

abstract：:The immunomodulatory properties of human endometrial mesenchymal stem cells (eMSC) have not been well characterised. Initial studies showed that eMSC modulated the chronic inflammatory response to a non-degradable polyamide/gelatin mesh in a xenogeneic rat skin wound repair model, but the mechanism remains unclear. In...

journal_title：Scientific reports

authors： Darzi S,Deane JA,Nold CA,Edwards SE,Gough DJ,Mukherjee S,Gurung S,Tan KS,Vashi AV,Werkmeister JA,Gargett CE

更新日期：2018-04-26 00:00:00

abstract：:Development of tissue engineering scaffolds with native-like biology and microarchitectures is a prerequisite for stem cell mediated generation of off-the-shelf-tissues. So far, the field of tissue engineering has not full-filled its grand potential of engineering such combinatorial scaffolds for engineering functiona...

journal_title：Scientific reports

authors： Guermani E,Shaki H,Mohanty S,Mehrali M,Arpanaei A,Gaharwar AK,Dolatshahi-Pirouz A

更新日期：2016-07-28 00:00:00

abstract：:The molecular dissociation constant, Kd, is a well-established parameter to quantitate the affinity of protein-protein or other molecular interactions. Recently, we reported the theoretical basis and experimental procedure for Kd determination using a quantitative FRET method. Here we report a new development of Kd de...

journal_title：Scientific reports

authors： Jiang L,Xiong Z,Song Y,Lu Y,Chen Y,Schultz JS,Li J,Liao J

更新日期：2019-02-14 00:00:00

abstract：:CHF5633 is a novel synthetic clinical pulmonary surfactant preparation composed by two phospholipid species, dipalmitoyl phosphatidylcholine (DPPC) and palmitoyloleoyl phosphatidylglycerol (POPG), and synthetic analogues of the hydrophobic surfactant proteins SP-B and SP-C. In this study, the interfacial properties of...

journal_title：Scientific reports

authors： Echaide M,Autilio C,López-Rodríguez E,Cruz A,Pérez-Gil J

更新日期：2020-01-28 00:00:00

abstract：:Hypertension is the most common and lethal risk factor for cardiovascular disease (CVD). Numerous variants have been associated with hypertension, however, most of which failed to get replication due to ethnic differences. In this study, we analyzed associations of 10 newly reported single nucleotide polymorphisms (SN...

journal_title：Scientific reports

authors： Yu Q,Sun HP,Chen WQ,Chen XQ,Xu Y,He YH,Kong QP

更新日期：2015-10-21 00:00:00

abstract：:We report the impact of anti-urothelial autoantibody (AUAb) on urinary bladder phenotype in BALB/c mice deficient of the FcγRIIb and PD-1. AUAb was present in serum samples from approximately half of the double-knockout (DKO) mice, as detected by immunofluorescence and immunoblots for urothelial proteins including uro...

journal_title：Scientific reports

authors： Sugino Y,Nishikawa N,Yoshimura K,Kuno S,Hayashi Y,Yoshimura N,Okazaki T,Kanematsu A,Ogawa O

更新日期：2012-01-01 00:00:00

abstract：:Switching magnetizations with femtosecond circularly polarized lasers may have revolutionary impacts on magnetic data storage and relevant applications. Achievements in ferrimagnetic and ferromagnetic materials of various structures strongly imply a general phenomenon of fundamental atom-laser interaction. Rotating an...

journal_title：Scientific reports

authors： Chen XJ

更新日期：2017-01-24 00:00:00

abstract：:Previous studies highlight the winners and losers in fisheries under climate change based on shifts in biomass, species composition and potential catches. Understanding how climate change is likely to alter the fisheries revenues of maritime countries is a crucial next step towards the development of effective socio-e...

journal_title：Scientific reports

authors： Lam VW,Cheung WW,Reygondeau G,Sumaila UR

更新日期：2016-09-07 00:00:00

abstract：:The prevalence of patients on automated peritoneal dialysis (APD) is increasing worldwide and may be guided by clinical characteristics, financial issues and patient option. Whether socioeconomic factors at the patient level may influence the decision for the initial peritoneal dialysis (PD) modality is unknown. This ...

journal_title：Scientific reports

authors： Pecoits-Filho R,Ribeiro SC,Kirk A,da Silva HS,Pille A,Falavinha RS Jr,Filho SS,Figueiredo AE,Barretti P,de Moraes TP

更新日期：2017-07-12 00:00:00

abstract：:The aim was to determine the effects of changing pulse duration and electrode size on muscle contractile properties. Thirty-six healthy young male participated in the study (age 24.8 ± 5.8 years; height 178.2 ± 0.6 cm; body mass 71.8 ± 7.3 kg; self-reported weekly moderate intensity activity 3.5 ± 1.2 h·week-1). Tensi...

journal_title：Scientific reports

authors： Piqueras-Sanchiz F,Martín-Rodríguez S,Pareja-Blanco F,Baraja-Vegas L,Blázquez-Fernández J,Bautista IJ,García-García Ó

更新日期：2020-05-18 00:00:00

abstract：:Cross-linked protein crystals (CLPCs) are very useful materials in applications such as biosensors, catalysis, and X-ray crystallography. Hence, preparation of CLPCs is an important research direction. During the preparation of CLPCs, an often encountered problem is that cracks may appear in the crystals, which may fi...

journal_title：Scientific reports

authors： Yan EK,Lu QQ,Zhang CY,Liu YL,He J,Chen D,Wang B,Zhou RB,Wu P,Yin DC

更新日期：2016-10-05 00:00:00

abstract：:Society's techno-social systems are becoming ever faster and more computer-orientated. However, far from simply generating faster versions of existing behaviour, we show that this speed-up can generate a new behavioural regime as humans lose the ability to intervene in real time. Analyzing millisecond-scale data for t...

journal_title：Scientific reports

authors： Johnson N,Zhao G,Hunsader E,Qi H,Johnson N,Meng J,Tivnan B

更新日期：2013-01-01 00:00:00

abstract：:Using analytical expressions for the magnetization textures of thin submicron-sized magnetic cylinders in vortex state, we derive closed-form algebraic expressions for the ensuing small-angle neutron scattering (SANS) cross sections. Specifically, for the perpendicular and parallel scattering geometries, we have compu...

journal_title：Scientific reports

authors： Metlov KL,Michels A

更新日期：2016-04-26 00:00:00

abstract：:Traumatic brain injury (TBI) increases the risk of Alzheimer's disease (AD). Calpain activation and tau hyperphosphorylation have been implicated in both TBI and AD. However, the link between calpain and tau phosphorylation has not been fully identified. We recently discovered that the two major calpain isoforms in th...

journal_title：Scientific reports

authors： Wang Y,Hall RA,Lee M,Kamgar-Parsi A,Bi X,Baudry M

更新日期：2017-09-18 00:00:00

abstract：:Copper ions play a vital role in a variety of fundamental physiological processes not only in human beings and plants, but also for extensive insects and microorganisms. In this paper, a novel water-soluble ruthenium(II) complex as a turn-on copper(II) ions luminescent sensor based on o-(phenylazo)aniline was designed...

journal_title：Scientific reports

authors： Zhang Y,Liu Z,Yang K,Zhang Y,Xu Y,Li H,Wang C,Lu A,Sun S

更新日期：2015-02-02 00:00:00

abstract：:Wooden shipwrecks are a significant part of the underwater cultural heritage. In 2007, the Nanhai No. 1 shipwreck was salvaged from the seabed and moved into the Marine Silk Road Museum, where it is still stored in a water tank. We analysed the microbial communities colonizing the hull surface of the Nanhai No. 1 ship...

journal_title：Scientific reports

authors： Liu Z,Fu T,Hu C,Shen D,Macchioni N,Sozzi L,Chen Y,Liu J,Tian X,Ge Q,Feng Z,Liu H,Zhang Z,Pan J

更新日期：2018-05-08 00:00:00

abstract：:Microalgal harvesting and dewatering are the main bottlenecks that need to be overcome to tap the potential of microalgae for production of valuable compounds. Water surface-floating microalgae form robust biofilms, float on the water surface along with gas bubbles entrapped under the biofilms, and have great potentia...

journal_title：Scientific reports

authors： Maeda Y,Nojima D,Sakurai M,Nomaguchi T,Ichikawa M,Ishizuka Y,Tanaka T

更新日期：2019-08-01 00:00:00

abstract：:Bone marrow and adipose tissue represent the two most commonly exploited sources of adult mesenchymal stem cells for musculoskeletal applications. Unfortunately the sampling of bone marrow and fat tissue is invasive and does not always lead to a sufficient number of cells. The present study describes a novel sampling ...

journal_title：Scientific reports

authors： Ceusters J,Lejeune JP,Sandersen C,Niesten A,Lagneaux L,Serteyn D

更新日期：2017-04-06 00:00:00

abstract：:With the development and application of nanotechnology, large amounts of nanoparticles will be potentially released to the environment and possibly cause many severe health problems. Although the toxicity of nanoparticles has been investigated, prevention and treatment of damages caused by nanoparticles have been rare...

journal_title：Scientific reports

authors： Qi W,Tian L,An W,Wu Q,Liu J,Jiang C,Yang J,Tang B,Zhang Y,Xie K,Wang X,Li Z,Wu W

更新日期：2017-06-06 00:00:00

abstract：:MicroRNAs (miRNAs) have been considered to be potent biomarkers for early disease diagnosis and for cancer therapy. The rapid and selective detection of miRNAs without reverse transcription and labelling is highly desired. Herein, we report a simple and label-free miRNA detection method that is based on the Duplex-Spe...

journal_title：Scientific reports

authors： Yan L,Yan Y,Pei L,Wei W,Zhao J

更新日期：2014-12-10 00:00:00

abstract：:In the current report, we describe the identification of three genetically distinct groups of prophages integrated into three different chromosomal sites of human gut-associated Bifidobacterium breve and Bifidobacterium longum strains. These bifidobacterial prophages are distantly related to temperate actinobacterioph...

journal_title：Scientific reports

authors： Mavrich TN,Casey E,Oliveira J,Bottacini F,James K,Franz CMAP,Lugli GA,Neve H,Ventura M,Hatfull GF,Mahony J,van Sinderen D

更新日期：2018-08-24 00:00:00