Mechanomyographic Measures of Muscle Contractile Properties are Influenced by Electrode Size and Stimulation Pulse Duration.

abstract：:The growing amount of longitudinal data for a large population of patients has necessitated the application of algorithms that can discover patterns to inform patient management. This study demonstrates how temporal patterns generated from a combination of clinical and imaging measurements improve residual survival pr...

journal_title：Scientific reports

authors： Smedley NF,Ellingson BM,Cloughesy TF,Hsu W

更新日期：2018-09-26 00:00:00

abstract：:Familial breast cancer is estimated to account for 15-20% of all cases of breast cancer. Surveillance for familial breast cancer is well-established world-wide. However, this service does not exist in Jordan, due to the scarcity of information with regard to the genetic profiling of these patients, and therefore lack ...

journal_title：Scientific reports

authors： Abu-Helalah M,Azab B,Mubaidin R,Ali D,Jafar H,Alshraideh H,Drou N,Awidi A

更新日期：2020-10-16 00:00:00

abstract：:Chemotherapy can cause cachexia, which consists of weight loss associated with muscle atrophy. The exact mechanisms underlying this skeletal muscle toxicity are largely unknown and co-therapies to attenuate chemotherapy-induced side effects are lacking. By using a rat model of cisplatin-induced cachexia, we here chara...

journal_title：Scientific reports

authors： Sirago G,Conte E,Fracasso F,Cormio A,Fehrentz JA,Martinez J,Musicco C,Camerino GM,Fonzino A,Rizzi L,Torsello A,Lezza AMS,Liantonio A,Cantatore P,Pesce V

更新日期：2017-10-12 00:00:00

abstract：:Low Haemoglobin concentration (Hb) among women of reproductive age is a severe public health problem in sub-Saharan Africa. This study investigated the effects of putative socio-demographic factors on maternal Hb at different points of the conditional distribution of Hb concentration. We utilised quantile regression t...

journal_title：Scientific reports

authors： Amugsi DA,Dimbuene ZT,Kyobutungi C

更新日期：2020-12-07 00:00:00

abstract：:Here we proposed a novel architectural design of a ternary MnO2-based electrode - a hierarchical Co3O4@Pt@MnO2 core-shell-shell structure, where the complemental features of the three key components (a well-defined Co3O4 nanowire array on the conductive Ti substrate, an ultrathin layer of small Pt nanoparticles, and a...

journal_title：Scientific reports

authors： Xia H,Zhu D,Luo Z,Yu Y,Shi X,Yuan G,Xie J

更新日期：2013-10-17 00:00:00

abstract：:Antibody-dependent cell-mediated cytotoxicity (ADCC) is an important mechanism of action for many therapeutic antibodies. A therapeutic immunoglobulin (Ig) G1 monoclonal antibody lost more than half of its ADCC activity after heat stress at 40 °C for 4 months. Size-exclusion and ion-exchange chromatography were used t...

journal_title：Scientific reports

authors： Lu X,Machiesky LA,De Mel N,Du Q,Xu W,Washabaugh M,Jiang XR,Wang J

更新日期：2020-01-15 00:00:00

abstract：:Tumor-associated macrophages (TAMs) play critical roles in promoting tumor progression and invasion. However, the molecular mechanisms underlying TAM regulation remain to be further investigated and may make significant contributions to cancer treatment. Mammalian microRNAs (miRNAs) have recently been identified as im...

journal_title：Scientific reports

authors： Li Y,Zhao L,Shi B,Ma S,Xu Z,Ge Y,Liu Y,Zheng D,Shi J

更新日期：2015-12-22 00:00:00

abstract：:Targeting embryonic stem cells (ESCs) is important for ESC labeling, drug delivery and cell fate control. In this study, we identified twenty-two phage clones that bind specifically to the hESC cell line X-01, which was derived from human blastocysts of Chinese origin. One phage (H178), which displays the sequence VGG...

journal_title：Scientific reports

authors： Zhao W,Jin L,Yuan H,Tan Z,Zhou C,Li LS,Ma L

更新日期：2013-11-05 00:00:00

abstract：:Obesity, often represented by higher body mass index (BMI), is not yet fully understood as a potential risk factor for poor clinical outcomes of prostate cancer (PCa) after radical prostatectomy (RP). This study aimed to evaluate the relationship between BMI and biochemical recurrence (BCR)-free survival in RP patient...

journal_title：Scientific reports

authors： Yu YD,Byun SS,Lee SE,Hong SK

更新日期：2018-08-10 00:00:00

abstract：:In this paper, we explore the concept of structural Luneburg lens (SLL) as a design framework for performing dynamic structural tailoring to obtain a structural wave cloak and a structural waveguide. The SLL is a graded refractive index lens, which is realized by using a variable thickness structure defined in a thin ...

journal_title：Scientific reports

authors： Zhao L,Yu M

更新日期：2020-09-03 00:00:00

abstract：:Kaposis's sarcoma associated herpesvirus (KSHV) has been reported to infect, among others, monocytes and dendritic cells DCs impairing their function. However, the underlying mechanisms remain not completely elucidated yet. Here we show that DC exposure to active or UV-inactivated KSHV resulted in STAT3 phosphorylatio...

journal_title：Scientific reports

authors： Santarelli R,Gonnella R,Di Giovenale G,Cuomo L,Capobianchi A,Granato M,Gentile G,Faggioni A,Cirone M

更新日期：2014-02-28 00:00:00

abstract：:Recent findings suggest an association between obesity, loss of gut barrier function and changes in microbiota profiles. Our primary objective was to examine the effect of caloric restriction and subsequent weight reduction on gut permeability in obese women. The impact on inflammatory markers and fecal microbiota was...

journal_title：Scientific reports

authors： Ott B,Skurk T,Hastreiter L,Lagkouvardos I,Fischer S,Büttner J,Kellerer T,Clavel T,Rychlik M,Haller D,Hauner H

更新日期：2017-09-20 00:00:00

abstract：:By using highly aligned carbon nanotube (CNT) sheets of excellent optical transmittance and mechanical stretchability as both the current collector and active electrode, high-performance transparent and stretchable all-solid supercapacitors with a good stability were developed. A transmittance up to 75% at the wavelen...

journal_title：Scientific reports

authors： Chen T,Peng H,Durstock M,Dai L

更新日期：2014-01-09 00:00:00

abstract：:In the current study, the thermodynamics of the slag-metal equilibrium reaction between Inconel 718 Ni-based alloy and CaF2-CaO-Al2O3-MgO-TiO2 electroslag remelting (ESR)-type slags were systematically investigated in the temperature range from 1773 to 1973 K (1500 to 1700 °C). The equilibrium Al content increased wit...

journal_title：Scientific reports

authors： Duan S,Shi X,Mao M,Yang W,Han S,Guo H,Guo J

更新日期：2018-03-27 00:00:00

abstract：:Common estimates of external training intensity for resistance exercise do not incorporate inter-set recovery duration, and might not reflect the overall demands of training. This study aimed to assess novel metrics of exercise density (ED) during resistance exercise, and how these related to a physiological marker of...

journal_title：Scientific reports

authors： Marston KJ,Peiffer JJ,Newton MJ,Scott BR

更新日期：2017-07-17 00:00:00

abstract：:We aimed to characterize the type 2 diabetes mellitus (T2DM) epidemic and the role of key risk factors in Jordan between 1990-2050, and to forecast the T2DM-related costs. A recently-developed population-level T2DM mathematical model was adapted and applied to Jordan. The model was fitted to six population-based surve...

journal_title：Scientific reports

authors： Awad SF,Huangfu P,Dargham SR,Ajlouni K,Batieha A,Khader YS,Critchley JA,Abu-Raddad LJ

更新日期：2020-12-03 00:00:00

abstract：:Hexagonal Fe(3)Sn has many of the desirable properties for a new permanent magnet phase with a Curie temperature of 725 K, a saturation moment of 1.18 MA/m. and anisotropy energy, K1 of 1.8 MJ/m(3). However, contrary to earlier experimental reports, we found both experimentally and theoretically that the easy magnetic...

journal_title：Scientific reports

authors： Sales BC,Saparov B,McGuire MA,Singh DJ,Parker DS

更新日期：2014-11-12 00:00:00

abstract：:The behavior of diatomic molecular solids under pressure have attracted great interest and been extensively studied. Under ambient pressure, the structure of bromine is known to be a molecular phase (phase I). With increasing pressure, it transforms into an incommensurate phase (phase V) before eventually to a monoato...

journal_title：Scientific reports

authors： Wu M,Tse JS,Pan Y

更新日期：2016-05-09 00:00:00

abstract：:Schistosomes, unlike malaria parasites, are in their diploid stage when targeted by the human immune system. Diploids can be either homozygous or heterozygous. The difference has profound significance for developing immunity and yet has not previously been addressed. We examined the implications of zygosity on immunit...

journal_title：Scientific reports

authors： Xu X,Sun J,Zhang J,Wellems D,Qing X,McCutchan T,Pan W

更新日期：2012-01-01 00:00:00

abstract：:Antigen-presenting cells including dendritic cells (DCs) express mannan receptors (MR) on their surface, which can be exploited in cancer therapy by designing immune-stimulatory viruses coated with mannan-modified capsids that then bind to DCs and initiate a potent immune response. Although the combination of anti-ang...

journal_title：Scientific reports

authors： Wang Y,Zhang J,Wu Y,Ding ZY,Luo XM,Liu J,Zhong WN,Deng GH,Xia XY,Deng YT,Wei YQ,Jiang Y

更新日期：2015-06-18 00:00:00

abstract：:Growth in salmon aquaculture over the past two decades has raised concerns regarding the potential impacts of the industry on neighboring ecosystems and wild fish productivity. Despite limited evidence, sea lice have been identified as a major cause for the decline in some wild Pacific salmon populations on the west c...

journal_title：Scientific reports

authors： Nekouei O,Vanderstichel R,Thakur K,Arriagada G,Patanasatienkul T,Whittaker P,Milligan B,Stewardson L,Revie CW

更新日期：2018-03-05 00:00:00

abstract：:Metastasis of head and neck tumors is responsible for a high mortality rate. Understanding its biochemistry may allow insights into tumorigenesis. To that end we carried out RNA-Seq analyses of 5 SCC9 derived oral cancer cell lines displaying increased invasive potential. Differentially expressed genes (DEGs) were ann...

journal_title：Scientific reports

authors： Pérez-Valencia JA,Prosdocimi F,Cesari IM,da Costa IR,Furtado C,Agostini M,Rumjanek FD

更新日期：2018-01-31 00:00:00

abstract：:Environmental DNA (eDNA) metabarcoding has been used increasingly to assess biodiversity of aquatic vertebrates. However, there still remains to be developed a sampling design of eDNA metabarcoding that can ensure high detection rates of species with minimum total survey effort, especially for large-scale surveys of a...

journal_title：Scientific reports

authors： Sato H,Sogo Y,Doi H,Yamanaka H

更新日期：2017-11-01 00:00:00

abstract：:Arabidopsis thaliana contains the putative K+ efflux transporters KEA1-KEA6, similar to KefB and KefC of Escherichia coli. KEA1-KEA3 are involved in the regulation of photosynthetic electron transport and chloroplast development. KEA4-KEA6 mediate pH regulation of the endomembrane network during salinity stress. Howev...

journal_title：Scientific reports

authors： Tsujii M,Kera K,Hamamoto S,Kuromori T,Shikanai T,Uozumi N

更新日期：2019-07-11 00:00:00

abstract：:The unconventional myosin MYO18A that contains a PDZ domain is required for muscle integrity during zebrafish development. However, the mechanism by which it functions in myofibers is not clear. The presence of a PDZ domain suggests that MYO18A may interact with other partners to perform muscle-specific functions. Her...

journal_title：Scientific reports

authors： Cao JM,Cheng XN,Li SQ,Heller S,Xu ZG,Shi DL

更新日期：2016-11-08 00:00:00

abstract：:Antibodies are widely used for the detection of specific molecules such as peptides, proteins, and chemical compounds. The specificity of an antibody is therefore its most important feature. However, it is very difficult to confirm antibody specificity. Recently, we made a human protein array consisting of 19,712 kind...

journal_title：Scientific reports

authors： Morishita R,Sugiyama S,Denda M,Tokunaga S,Kido K,Shioya R,Ozawa S,Sawasaki T

更新日期：2019-12-18 00:00:00

abstract：:In this study, we had exploited the advancement in computer technology to determine the stability of four apomyoglobin variants namely wild type, E109A, E109G and G65A/G73A by conducting conventional molecular dynamics simulations in explicit urea solution. Variations in RMSD, native contacts and solvent accessible su...

journal_title：Scientific reports

authors： Zhang D,Lazim R

更新日期：2017-03-16 00:00:00

abstract：:The high transparency of graphene, together with its good electrical conductivity and mechanical robustness, enable its use as transparent electrodes in optoelectronic devices such as solar cells. While initial demonstrations of graphene-based organic photovoltaics (OPV) have been promising, realization of scalable te...

journal_title：Scientific reports

authors： Park H,Chang S,Smith M,Gradečak S,Kong J

更新日期：2013-01-01 00:00:00

abstract：:Cyanobacteria exhibit a great capacity to adapt to different environmental conditions through changes in gene expression. Although this plasticity has been extensively studied in the model cyanobacterium Synechocystis sp. PCC 6803, a detailed analysis of the coordinated transcriptional adaption across varying conditio...

journal_title：Scientific reports

authors： Hernández-Prieto MA,Semeniuk TA,Giner-Lamia J,Futschik ME

更新日期：2016-02-29 00:00:00

abstract：:Uterine carcinosarcomas (UCSs) are highly aggressive malignancies associated with poor prognoses and limited treatment options. These tumors are hypothesized to develop from the endometrial adenocarcinoma (EAC) through epithelial-mesenchymal transition (EMT). We test this long-standing hypothesis by depleting miR-200,...

journal_title：Scientific reports

authors： Tseng JH,Bisogna M,Hoang LN,Olvera N,Rodriguez-Aguayo C,Lopez-Berestein G,Sood AK,Levine DA,Jelinic P

更新日期：2017-06-15 00:00:00