The Transcriptional Landscape of the Photosynthetic Model Cyanobacterium Synechocystis sp. PCC6803.

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Gu H,Qi X,Jia Y,Zhang Z,Nie C,Li X,Li J,Jiang Z,Wang Q,Qu L

更新日期：2020-04-17 00:00:00

abstract：:We analyse theoretically the spatiotemporal dynamics of two incoherent counterpropagating Airy beams interacting in a photorefractive crystal under focusing conditions. For a large enough nonlinearity strength the interaction between the two Airy beams leads to light-induced waveguiding. The stability of the waveguide...

journal_title：Scientific reports

authors： Wiersma N,Marsal N,Sciamanna M,Wolfersberger D

更新日期：2015-08-28 00:00:00

abstract：:Living organisms have to adjust to their surrounding in order to survive in stressful conditions. We study this mechanism in one of most primitive creatures - photosynthetic green sulfur bacteria. These bacteria absorb photons very efficiently using the chlorosome antenna complexes and perform photosynthesis in extrem...

journal_title：Scientific reports

authors： Saikin SK,Khin Y,Huh J,Hannout M,Wang Y,Zare F,Aspuru-Guzik A,Tang JK

更新日期：2014-05-27 00:00:00

abstract：:Fungal laccases (EC 1.10.3.2) are multi-copper oxidases that oxidize a wide variety of substrates. Despite extensive studies, the molecular basis for their diverse activity is unclear. Notably, there is no current way to rationally predict the activity of a laccase toward a given substrate. Such knowledge would greatl...

journal_title：Scientific reports

authors： Mehra R,Muschiol J,Meyer AS,Kepp KP

更新日期：2018-11-23 00:00:00

abstract：:Large (>10 kb) palindromic sequences are enriched on mammalian sex chromosomes. In mice, these palindromes harbor gene families (≥2 gene copies) expressed exclusively in post-meiotic testicular germ cells, a time when most single-copy sex-linked genes are transcriptionally repressed. This observation led to the hypoth...

journal_title：Scientific reports

authors： Kruger AN,Ellison Q,Brogley MA,Gerlinger ER,Mueller JL

更新日期：2018-06-12 00:00:00

abstract：:A particular type of miniature ceramic vessel locally known as "veneneras" is occasionally found during archaeological excavations in the Maya Area. To date, only one study of a collection of such containers successfully identified organic residues through coupled chromatography-mass spectrometry methods. That study i...

journal_title：Scientific reports

authors： Zimmermann M,Brownstein KJ,Pantoja Díaz L,Ancona Aragón I,Hutson S,Kidder B,Tushingham S,Gang DR

更新日期：2021-01-15 00:00:00

abstract：:Electrochemical capacitors (EC) have received tremendous interest due to their high potential to satisfy the urgent demand in many advanced applications. The development of new electrode materials is considered to be the most promising approach to enhance the EC performance substantially. Herein, we present a high-cap...

journal_title：Scientific reports

authors： Zhou J,Li N,Gao F,Zhao Y,Hou L,Xu Z

更新日期：2014-08-15 00:00:00

abstract：:To increase the yield potential while limiting the environmental impact of N management practices is an important issue in rice cultivation. The large-grain rice cultivar Akita 63 showed higher N-use efficiency for grain production. To elucidate this, we analyzed yield characteristics of Akita 63 in comparison with th...

journal_title：Scientific reports

authors： Makino A,Kaneta Y,Obara M,Ishiyama K,Kanno K,Kondo E,Suzuki Y,Mae T

更新日期：2020-07-22 00:00:00

abstract：:Quantification of stillbirth risk has potential to support clinical decision-making. Studies that have attempted to quantify stillbirth risk have been hampered by small event rates, a limited range of predictors that typically exclude obstetric history, lack of validation, and restriction to a single classifier (logis...

journal_title：Scientific reports

authors： Malacova E,Tippaya S,Bailey HD,Chai K,Farrant BM,Gebremedhin AT,Leonard H,Marinovich ML,Nassar N,Phatak A,Raynes-Greenow C,Regan AK,Shand AW,Shepherd CCJ,Srinivasjois R,Tessema GA,Pereira G

更新日期：2020-03-24 00:00:00

abstract：:Two-dimensional (2D) cell cultures growing on plastic do not recapitulate the three dimensional (3D) architecture and complexity of human tumors. More representative models are required for drug discovery and validation. Here, 2D culture and 3D mono- and stromal co-culture models of increasing complexity have been est...

journal_title：Scientific reports

authors： Stock K,Estrada MF,Vidic S,Gjerde K,Rudisch A,Santo VE,Barbier M,Blom S,Arundkar SC,Selvam I,Osswald A,Stein Y,Gruenewald S,Brito C,van Weerden W,Rotter V,Boghaert E,Oren M,Sommergruber W,Chong Y,de Hoogt R,Grae

更新日期：2016-07-01 00:00:00

abstract：:Our previous studies demonstrated that volatile oil from saussurea lappa root (VOSL), rich in two natural sesquiterpene lactones, costunolide (Cos) and dehydrocostuslactone (Dehy), exerts better anti-breast cancer efficacy and lower side effects than Cos or Dehy alone in vivo, however, their anti-cancer molecular mech...

journal_title：Scientific reports

authors： Peng Z,Wang Y,Fan J,Lin X,Liu C,Xu Y,Ji W,Yan C,Su C

更新日期：2017-01-24 00:00:00

abstract：:Carbon nanotubes exhibit mechanical properties ideally suited for reinforced structural composites and surface area and conductivity attractive for electrochemical capacitors. Here we demonstrate the multifunctional synergy between these properties in a composite material exhibiting simultaneous mechanical and energy ...

journal_title：Scientific reports

authors： Muralidharan N,Teblum E,Westover AS,Schauben D,Itzhak A,Muallem M,Nessim GD,Pint CL

更新日期：2018-12-05 00:00:00

abstract：:Glioblastoma (GBM) is the most aggressive brain primary malignancy. Toll-like receptor 4 (TLR4) has a dual role in cell fate, promoting cell survival or death depending on the context. Here, we analyzed TLR4 expression in different grades of astrocytoma, and observed increased expression in tumors, mainly in GBM, comp...

journal_title：Scientific reports

authors： Moretti IF,Lerario AM,Trombetta-Lima M,Sola PR,da Silva Soares R,Oba-Shinjo SM,Marie SKN

更新日期：2021-01-14 00:00:00

abstract：:The Morris Water Maze is commonly used in behavioural neuroscience for the study of spatial learning with rodents. Over the years, various methods of analysing rodent data collected during this task have been proposed. These methods span from classical performance measurements to more sophisticated categorisation tech...

journal_title：Scientific reports

authors： Vouros A,Gehring TV,Szydlowska K,Janusz A,Tu Z,Croucher M,Lukasiuk K,Konopka W,Sandi C,Vasilaki E

更新日期：2018-10-10 00:00:00

abstract：:The inhibitors of CD26 (dipeptidyl peptidase-4; DPP4) have been widely prescribed to control glucose level in diabetic patients. DPP4-inhibitors, however, accumulate stromal cell-derived factor-1α (SDF-1α), a well-known inducer of vascular leakage and angiogenesis both of which are fundamental pathophysiology of diabe...

journal_title：Scientific reports

authors： Lee CS,Kim YG,Cho HJ,Park J,Jeong H,Lee SE,Lee SP,Kang HJ,Kim HS

更新日期：2016-07-06 00:00:00

abstract：:Although blood-based liquid biopsies have emerged as a promising non-invasive method to detect biomarkers in various cancers, limited progress has been made for brain tumors. One major obstacle is the blood-brain barrier (BBB), which hinders efficient passage of tumor biomarkers into the peripheral circulation. The ob...

journal_title：Scientific reports

authors： Zhu L,Cheng G,Ye D,Nazeri A,Yue Y,Liu W,Wang X,Dunn GP,Petti AA,Leuthardt EC,Chen H

更新日期：2018-04-26 00:00:00

abstract：:The autonomic nervous system (ANS) regulates tissue homeostasis and remodelling through antagonistic effects of noradrenergic sympathetic and cholinergic parasympathetic signalling. Despite numerous reports on the induction of sympathetic neurons from human pluripotent stem cells (hPSCs), no induction methods have eff...

journal_title：Scientific reports

authors： Takayama Y,Kushige H,Akagi Y,Suzuki Y,Kumagai Y,Kida YS

更新日期：2020-06-11 00:00:00

abstract：:Cytomegalovirus (CMV) is one of the infectious causes of hypertensive anterior uveitis, which is characterized by recurrent episodes of elevated intraocular pressure (IOP) and mild anterior uveitis. Despite the potentially vision-threatening complications of this disease, the underlying mechanisms remain largely undef...

journal_title：Scientific reports

authors： Choi JA,Kim JE,Noh SJ,Kyoung Kim E,Park CK,Paik SY

更新日期：2017-02-27 00:00:00

abstract：:Animal gut harbors diverse microbes that play crucial roles in the nutrition uptake, metabolism, and the regulation of host immune responses. The intestinal microbiota homeostasis is critical for health but poorly understood. Probiotics Paracoccus marcusii DB11 and Bacillus cereus G19, and antibiotics florfenicol did ...

journal_title：Scientific reports

authors： Yang G,Peng M,Tian X,Dong S

更新日期：2017-07-06 00:00:00

abstract：:The standardization of apiceutical products like as propolis extracts has been widely debated worldwide and variations in the propolis chemical composition are still very relevant topics for use-standardized of different propolis-type as medication by much of the world's population. The present manuscript discuss impo...

journal_title：Scientific reports

authors： do Nascimento TG,Dos Santos Arruda RE,da Cruz Almeida ET,Dos Santos Oliveira JM,Basílio-Júnior ID,Celerino de Moraes Porto IC,Rodrigues Sabino A,Tonholo J,Gray A,Ebel RE,Clements C,Zhang T,Watson DG

更新日期：2019-12-04 00:00:00

abstract：:The cycling between GDP- and GTP- bound forms of the Ras protein is partly regulated by the binding of Sos. The structural/dynamic behavior of the complex formed between activated Sos and Ras at the point of the functional cycle where the nucleotide exchange is completed has not been described to date. Here we show th...

journal_title：Scientific reports

authors： Vo U,Vajpai N,Embrey KJ,Golovanov AP

更新日期：2016-07-14 00:00:00

abstract：:Establishing the architecture of gene regulatory networks (GRNs) relies on chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-Seq) methods that provide genome-wide transcription factor binding sites (TFBSs). ChIP-Seq furnishes millions of short reads that, after alignment, describe the genom...

journal_title：Scientific reports

authors： Ouma WZ,Mejia-Guerra MK,Yilmaz A,Pareja-Tobes P,Li W,Doseff AI,Grotewold E

更新日期：2015-03-02 00:00:00

abstract：:Seabirds are known to concentrate on prey patches or at predators aggregations standing for potential feeding opportunities. They may search for prey using olfaction or by detecting visually feeding con-specifics and sub-surface predators, or even boats. Thus, they might form a foraging network. We hypothesized that c...

journal_title：Scientific reports

authors： Assali C,Bez N,Tremblay Y

更新日期：2017-08-04 00:00:00

abstract：:With modern scanning probe microscopes, it is possible to manipulate surface structures even at the atomic level. However, manipulation of nanoscale objects such as clusters is often more relevant and also more challenging due to the complicated interactions between the surface, cluster and apparatus. We demonstrate t...

journal_title：Scientific reports

authors： Hynninen T,Cabailh G,Foster AS,Barth C

更新日期：2013-01-01 00:00:00

abstract：:Tumour-associated macrophages mainly comprise immunosuppressive M2 phenotypes that promote tumour progression besides anti-tumoural M1 subsets. Selective depletion or reprogramming of M2 may represent an innovative anti-cancer strategy. The actin cytoskeleton is central for cellular homeostasis and is targeted for ant...

journal_title：Scientific reports

authors： Pergola C,Schubert K,Pace S,Ziereisen J,Nikels F,Scherer O,Hüttel S,Zahler S,Vollmar AM,Weinigel C,Rummler S,Müller R,Raasch M,Mosig A,Koeberle A,Werz O

更新日期：2017-01-30 00:00:00

abstract：:We investigate optical bound states in the continuum (BICs) supported by a photonic crystal (PhC) slab penetrated with periodic annular holes theoretically. Ultrahigh-quality factor (Q-factor) resonances associated with BICs are obtained with a Q-factor more than 108. The BICs can be seen at nonzero incident angles by...

journal_title：Scientific reports

authors： Li Z,Zhu Q,Wang Y,Xie S

更新日期：2018-08-20 00:00:00

abstract：:Molecular alignment underpins optical, mechanical, and thermal properties of materials, however, its direct measurement from volumes with micrometer dimensions is not accessible, especially, for structurally complex bio-materials. How the molecular alignment is linked to extraordinary properties of silk and its amorph...

journal_title：Scientific reports

authors： Ryu M,Balčytis A,Wang X,Vongsvivut J,Hikima Y,Li J,Tobin MJ,Juodkazis S,Morikawa J

更新日期：2017-08-07 00:00:00

abstract：:Generation and manipulation of quantum entangled electrons is an important concept in quantum mechanics, and necessary for advances in quantum information processing; but not yet established in solid state systems. A promising device is a superconductor-two quantum dots Cooper pair splitter. Early nanowire based devic...

journal_title：Scientific reports

authors： Borzenets IV,Shimazaki Y,Jones GF,Craciun MF,Russo S,Yamamoto M,Tarucha S

更新日期：2016-03-14 00:00:00

abstract：:Many scientists are seeking better therapies for treating fibromyalgia (FM) pain. We used a mouse model of FM to determine if ASIC3 and its relevant signaling pathway participated in FM pain. We demonstrated that FM-induced mechanical hyperalgesia was attenuated by electroacupuncture (EA). The decrease in fatigue-indu...

journal_title：Scientific reports

authors： Yen LT,Hsieh CL,Hsu HC,Lin YW

更新日期：2017-04-25 00:00:00

abstract：:While nanowires and nanospheres have been utilized in the design of a diverse array of nanoscale devices, recent schemes frequently require nanoscale architectures of higher complexity. However, conventional techniques are largely unsatisfactory for the production of more intricate nanoscale shapes and patterns, and e...

journal_title：Scientific reports

authors： Khudiyev T,Tobail O,Bayindir M

更新日期：2014-05-06 00:00:00