miR-200c-driven Mesenchymal-To-Epithelial Transition is a Therapeutic Target in Uterine Carcinosarcomas.

abstract：:The role of isochrony in speech-the hypothetical division of speech units into equal duration intervals-has been the subject of a long-standing debate. Current approaches in neurosciences have brought new perspectives in that debate through the theoretical framework of predictive coding and cortical oscillations. Here...

journal_title：Scientific reports

authors： Aubanel V,Schwartz JL

更新日期：2020-11-11 00:00:00

abstract：:The estrogen receptor (ER) regulates the survival and growth of breast cancer cells, but it is less clear how components of the tissue microenvironment affect ER-mediated responses. We set out to test how human mammary fibroblasts (HMFs) modulate ER signaling and downstream cellular responses. We exposed an organotypi...

journal_title：Scientific reports

authors： Morgan MM,Livingston MK,Warrick JW,Stanek EM,Alarid ET,Beebe DJ,Johnson BP

更新日期：2018-05-08 00:00:00

abstract：:This work considers the effects of the Hurst exponent (H) on the local electric field distribution and the slope of the Fowler-Nordheim (FN) plot when considering the cold field electron emission properties of rough Large-Area Conducting Field Emitter Surfaces (LACFESs). A LACFES is represented by a self-affine Weiers...

journal_title：Scientific reports

authors： de Assis TA

更新日期：2015-06-02 00:00:00

abstract：:Formamidinium lead iodide (CH(NH2)2PbI3, FAPI) thin films have been deposited on glass substrates at 150 °C using ambient pressure aerosol assisted chemical vapour deposition (AACVD). The films have been analysed by a range of techniques including powder X-ray diffraction (pXRD), scanning electron microscopy (SEM), en...

journal_title：Scientific reports

authors： Alam F,Lewis DJ

更新日期：2020-12-17 00:00:00

abstract：:Flavivirus-mediated inflammation causes neuronal death, but whether the infected neurons can evoke an innate immune response to elicit their own protection, is unknown. In an earlier study we have shown that neuronal RIG-I, play a significant role in inducing production and release of molecules that are related to inf...

journal_title：Scientific reports

authors： Nazmi A,Mukhopadhyay R,Dutta K,Basu A

更新日期：2012-01-01 00:00:00

abstract：:There is significant interest in understanding the pathophysiology of Obsessive-Compulsive Disorder (OCD) using resting-state fMRI (rsfMRI). Previous studies acknowledge abnormalities within and beyond the fronto-striato-limbic circuit in OCD that require further clarifications. However, limited information could be i...

journal_title：Scientific reports

authors： Kashyap R,Eng GK,Bhattacharjee S,Gupta B,Ho R,Ho CSH,Zhang M,Mahendran R,Sim K,Chen SHA

更新日期：2021-01-14 00:00:00

abstract：:Rheumatoid Arthritis (RA) causes chronic inflammation of joints. The cytokines TNFα and IFNγ are central players in RA, however their source has not been fully elucidated. Natural Killer (NK) cells are best known for their role in elimination of viral-infected and transformed cells, and they secrete pro-inflammatory c...

journal_title：Scientific reports

authors： Yamin R,Berhani O,Peleg H,Aamar S,Stein N,Gamliel M,Hindi I,Scheiman-Elazary A,Gur C

更新日期：2019-02-04 00:00:00

abstract：:During Antarctic isolation personnel are exposed to extreme photoperiods. A frequent observation is a sleep onset phase delay during winter. It is not known if, as a result, daytime sleeping in the form of naps increases. We sought to assess sleep patterns - with focus on daytime sleeping - and alertness in a Latin Am...

journal_title：Scientific reports

authors： Folgueira A,Simonelli G,Plano S,Tortello C,Cuiuli JM,Blanchard A,Patagua A,Brager AJ,Capaldi VF,Aubert AE,Barbarito M,Golombek DA,Vigo DE

更新日期：2019-07-26 00:00:00

abstract：:Necrotizing enterocolitis (NEC) is a devastating gastrointestinal emergency of neonates. Epithelial tight junction (TJ) proteins, such as claudins, are essential for regulation and function of the intestinal barrier. Rho kinase (ROCK) affects cellular permeability and TJ regulation. We hypothesized that TJ protein cha...

journal_title：Scientific reports

authors： Ares G,Buonpane C,Sincavage J,Yuan C,Wood DR,Hunter CJ

更新日期：2019-03-21 00:00:00

abstract：:In order to improve the accuracy and reliability of micropipetting, a method of micro-pipette detection and calibration combining the dynamic pressure monitoring in pipetting process and quantitative identification of pipette volume in image processing was proposed. Firstly, the normalized pressure model for the pipet...

journal_title：Scientific reports

authors： Shang Z,Zhou X,Li C,Tsai SB

更新日期：2018-04-10 00:00:00

abstract：:Photonic integrated circuits for photonic computing open up the possibility for the realization of ultrahigh-speed and ultra wide-band signal processing with compact size and low power consumption. Differential equations model and govern fundamental physical phenomena and engineering systems in virtually any field of ...

journal_title：Scientific reports

authors： Yang T,Dong J,Lu L,Zhou L,Zheng A,Zhang X,Chen J

更新日期：2014-07-04 00:00:00

abstract：:Phytic acid (PA) is the primary phosphorus (P) storage compound in the seeds of cereals and legumes. Low PA crops, which are considered an effective way to improve grain nutrient availability and combat environmental issues relating to seed P have been developed using mutational and reverse genetics approaches. Here, ...

journal_title：Scientific reports

authors： Perera I,Fukushima A,Akabane T,Horiguchi G,Seneweera S,Hirotsu N

更新日期：2019-10-16 00:00:00

abstract：:Biochemical remission after transsphenoidal surgery is still unsatisfied in acromegaly patients with macroadenomas, especially with invasive macroadenomas. Concerning the impact of preoperative somatostatin analogues (SSAs) on surgical outcomes, previous studies with limited cases reported conflicting results. To asse...

journal_title：Scientific reports

authors： Yang C,Li G,Jiang S,Bao X,Wang R

更新日期：2019-10-01 00:00:00

abstract：:While considered an extracellular pathogen, Pseudomonas aeruginosa has been reported to be engulfed by macrophages in cellular and animal models. However, the role of macrophages in P. aeruginosa clearance in vivo remains poorly studied. The major outer membrane porin OprF has been recently shown to be involved in P. ...

journal_title：Scientific reports

authors： Moussouni M,Berry L,Sipka T,Nguyen-Chi M,Blanc-Potard AB

更新日期：2021-01-11 00:00:00

abstract：:Crystallization is the bottleneck in macromolecular crystallography; even when a protein crystallises, crystal packing often influences ligand-binding and protein-protein interaction interfaces, which are the key points of interest for functional and drug discovery studies. The human hypoxia-inducible factor prolyl hy...

journal_title：Scientific reports

authors： Chowdhury R,Abboud MI,McAllister TE,Banerji B,Bhushan B,Sorensen JL,Kawamura A,Schofield CJ

更新日期：2020-12-15 00:00:00

abstract：:Microscopic swimming devices hold promise for radically new applications in lab-on-a-chip and microfluidic technology, diagnostics and drug delivery etc. In this paper, we demonstrate the experimental verification of a new class of autonomous ferromagnetic swimming devices, actuated and controlled solely by an oscilla...

journal_title：Scientific reports

authors： Hamilton JK,Petrov PG,Winlove CP,Gilbert AD,Bryan MT,Ogrin FY

更新日期：2017-03-09 00:00:00

abstract：:New small molecules that regulate the step-wise differentiation of human pluripotent stem cells into dopaminergic neurons have been identified. The steroid, guggulsterone, was found to be the most effective inducer of neural stem cells into dopaminergic neurons. These neurons are extensively characterized and shown to...

journal_title：Scientific reports

authors： Gonzalez R,Garitaonandia I,Abramihina T,Wambua GK,Ostrowska A,Brock M,Noskov A,Boscolo FS,Craw JS,Laurent LC,Snyder EY,Semechkin RA

更新日期：2013-01-01 00:00:00

abstract：:Recent studies have elucidated the crucial role for microRNAs in peripheral nerve myelination by ablating components of the microRNA synthesis machinery. Few studies have focused on the role of individual microRNAs. To fill this gap, we focused this study on miR-138, which was shown to be drastically reduced in Dicer1...

journal_title：Scientific reports

authors： Lin HP,Oksuz I,Svaren J,Awatramani R

更新日期：2018-02-28 00:00:00

abstract：:The lack of vaccines and antiviral treatment, along with the increasing number of cases of Zika virus (ZIKV) and Chikungunya virus (CHIKV) infections, emphasize the need for searching for new therapeutic strategies. In this context, the marine brown seaweed Canistrocarpus cervicornis has been proved to hold great anti...

journal_title：Scientific reports

authors： Cirne-Santos CC,de Souza Barros C,de Oliveira MC,Rabelo VW,Azevedo RC,Teixeira VL,Ferreira DF,de Palmer Paixão ICN

更新日期：2020-05-19 00:00:00

abstract：:Achieving 180° magnetization reversal with an electric field rather than a current or magnetic field is a fundamental challenge and represents a technological breakthrough towards new memory cell designs. Here we propose a mesoscale morphological engineering approach to accomplishing full 180° magnetization reversals ...

journal_title：Scientific reports

authors： Wang JJ,Hu JM,Ma J,Zhang JX,Chen LQ,Nan CW

更新日期：2014-12-16 00:00:00

abstract：:Leukemia cells are superior to hematopoietic cells with a normal differentiation potential in buffering cellular stresses, but the underlying mechanisms for this leukemic advantage are not fully understood. Using CRISPR/Cas9 deletion of the canonical autophagy-essential gene Atg7, we found that erythroleukemia K562 ce...

journal_title：Scientific reports

authors： Wang J,Fang Y,Yan L,Yuan N,Zhang S,Xu L,Nie M,Zhang X,Wang J

更新日期：2016-04-19 00:00:00

abstract：:The changes of balance control mechanism caused by lumbar disc herniation (LDH) has not been well understood. This study aimed to investigate the effects of LDH on the balance control during standing on sloped surfaces. Ten patients with LDH and 10 gender- and age-matched healthy subjects were instructed to stand quie...

journal_title：Scientific reports

authors： Li J,Zhang Y,Song S,Hou Y,Hong Y,Yue S,Li K

更新日期：2020-02-03 00:00:00

abstract：:The use of micro- and nanodevices as multifunctional systems for biomedical applications has experienced an exponential growth during the past decades. Although a large number of studies have focused on the design and fabrication of new micro- and nanosystems capable of developing multiple functions, a deeper understa...

journal_title：Scientific reports

authors： Patiño T,Soriano J,Barrios L,Ibáñez E,Nogués C

更新日期：2015-06-12 00:00:00

abstract：:Most large herbivores in arid landscapes need to drink which constrains their movements and makes them vulnerable to disturbance. Asiatic wild ass or khulan (Equus hemionus) were widespread and abundant throughout the arid landscapes of Central Asia and Mongolia, but have undergone dramatic population declines and ran...

journal_title：Scientific reports

authors： Payne JC,Buuveibaatar B,Bowler DE,Olson KA,Walzer C,Kaczensky P

更新日期：2020-02-19 00:00:00

abstract：:Gapmer antisense oligonucleotides cleave target RNA effectively in vivo, and is considered as promising therapeutics. Especially, gapmers modified with locked nucleic acid (LNA) shows potent knockdown activity; however, they also cause hepatotoxic side effects. For developing safe and effective gapmer drugs, a deeper ...

journal_title：Scientific reports

authors： Kasuya T,Hori S,Watanabe A,Nakajima M,Gahara Y,Rokushima M,Yanagimoto T,Kugimiya A

更新日期：2016-07-27 00:00:00

abstract：:With the aim to capture and subsequent selective trapping of CO2, a nanocomposite has been developed through selective modification of the outer surface of the halloysite nanotubes (HNTs) with an organosilane to make the nanocomposite a novel solid-phase adsorbent to adsorb CO2 from the atmosphere at standard ambient ...

journal_title：Scientific reports

authors： Jana S,Das S,Ghosh C,Maity A,Pradhan M

更新日期：2015-03-04 00:00:00

abstract：:A better understanding of the seroprevalence and specificity of influenza HA stem-directed broadly neutralizing antibodies (bNAbs) in the human population could significantly inform influenza vaccine design efforts. Here, we utilized probes comprising headless, HA stabilized stem (SS) to determine the prevalence, bind...

journal_title：Scientific reports

authors： Yassine HM,McTamney PM,Boyington JC,Ruckwardt TJ,Crank MC,Smatti MK,Ledgerwood JE,Graham BS

更新日期：2018-06-05 00:00:00

abstract：:Parasitic lice (order Phthiraptera) infest birds and mammals. The typical animal mitochondrial (mt) genome organization, which consists of a single chromosome with 37 genes, was found in chewing lice in the suborders Amblycera and Ischnocera. The sucking lice (suborder Anoplura) known, however, have fragmented mt geno...

journal_title：Scientific reports

authors： Shao R,Barker SC,Li H,Song S,Poudel S,Su Y

更新日期：2015-11-30 00:00:00

abstract：:A cerebral aneurysm occurs as a result of a weakened blood vessel, which allows blood to flow into a sac or a ballooned section. Recent advancement shows that a new device, 'flow-diverter', can divert blood flow away from the aneurysm sac. People found that a flow-diverter based on thin film nitinol (TFN), works very ...

journal_title：Scientific reports

authors： Chen Y,Howe C,Lee Y,Cheon S,Yeo WH,Chun Y

更新日期：2016-03-24 00:00:00

abstract：:Lambdoid craniosynostosis (LC) is a rare non-syndromic craniosynostosis characterised by fusion of the lambdoid sutures at the back of the head. Surgical correction including the spring assisted cranioplasty is the only option to correct the asymmetry at the skull in LC. However, the aesthetic outcome from spring assi...

journal_title：Scientific reports

authors： Bozkurt S,Borghi A,van de Lande LS,Jeelani NUO,Dunaway DJ,Schievano S

更新日期：2020-10-29 00:00:00