Growth hormone secretagogues hexarelin and JMV2894 protect skeletal muscle from mitochondrial damages in a rat model of cisplatin-induced cachexia.

abstract：:Radical cystectomy (RC) together with bilateral pelvic lymph node dissection remains the standard treatment for muscle invasive bladder cancer (MIBC). However, radiation-based treatments such as tri-modal therapy (TMT) involving maximally performed transurethral resection of bladder tumor (TURBT), radiotherapy (XRT), ...

journal_title：Scientific reports

authors： Ayoub M,Shinde-Jadhav S,Mansure JJ,Alvarez F,Connell T,Seuntjens J,Piccirillo CA,Kassouf W

更新日期：2019-04-23 00:00:00

abstract：:Three-dimensionally (3D) porous morphology of nanostructures can effectively improve their electrocatalytic activity and durability for various electrochemical reactions owing to big surface area and interconnected structure. Cyanogel, a jelly-like inorganic polymer, can be used to synthesize various three-dimensional...

journal_title：Scientific reports

authors： Liu X,Xu G,Chen Y,Lu T,Tang Y,Xing W

更新日期：2015-01-05 00:00:00

abstract：:Most glioblastoma patients have a dismal prognosis, although some survive several years. However, only few biomarkers are available to predict the disease course. EGR1 and EGR3 have been linked to glioblastoma stemness and tumour progression, and this study aimed to investigate their spatial expression and prognostic ...

journal_title：Scientific reports

authors： Knudsen AM,Eilertsen I,Kielland S,Pedersen MW,Sørensen MD,Dahlrot RH,Boldt HB,Munthe S,Poulsen FR,Kristensen BW

更新日期：2020-06-09 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Tsuchiya K,Suzuki Y,Yoshimura K,Yasui H,Karayama M,Hozumi H,Furuhashi K,Enomoto N,Fujisawa T,Nakamura Y,Inui N,Yokomura K,Suda T

更新日期：2020-02-19 00:00:00

abstract：:This work provides new insights into the dynamics of silica nanoparticle-based removal of organic fluids (here oil) from naturally occurring porous media. We have used 4D (time-resolved 3D) imaging at pore-scale using X-ray computed micro-tomography (μCT) technique. The captured 3D tomographic time-series data reveal ...

journal_title：Scientific reports

authors： Pak T,Archilha NL,Mantovani IF,Moreira AC,Butler IB

更新日期：2018-07-24 00:00:00

abstract：:The concept of multiscale architectured materials is established using composition and grain size gradients. Composition-gradient nanostructured materials are produced from coarse grained interstitial free steels via carburization and high-pressure torsion. Quantitative analyses of the dislocation density using X-ray ...

journal_title：Scientific reports

authors： Kang JY,Kim JG,Park HW,Kim HS

更新日期：2016-05-27 00:00:00

abstract：:In-stent restenosis (ISR) remains the leading problem encountered after percutaneous coronary intervention (PCI). Thiazolidinediones (TZDs) has been shown to be associated with reduced ISR and target lesion revascularization (TLR); however, the results are inconsistent, especially between rosiglitazone and pioglitazon...

journal_title：Scientific reports

authors： Zhou X,Chen S,Zhu M,Hua J,Dai J,Xu X,Qiu Y,Mao W

更新日期：2017-10-31 00:00:00

abstract：:Associations between HLA class I alleles and HIV progression in populations exhibiting Amerindian and Caucasian genetic admixture remain understudied. Using univariable and multivariable analyses we evaluated HLA associations with five HIV clinical parameters in 3,213 HIV clade B-infected, ART-naïve individuals from M...

journal_title：Scientific reports

authors： Valenzuela-Ponce H,Alva-Hernández S,Garrido-Rodríguez D,Soto-Nava M,García-Téllez T,Escamilla-Gómez T,García-Morales C,Quiroz-Morales VS,Tapia-Trejo D,Del Arenal-Sánchez S,Prado-Galbarro FJ,Hernández-Juan R,Rodríguez-Aguirre E,

更新日期：2018-04-17 00:00:00

abstract：:The transition energies and formation energies of N, C, F, Cl, and S as substitutional dopants in Ag3PO4 are studied using first-principles calculations based on the hybrid Hartree-Fock density functional, which correctly reproduces the band gap and thus provides the accurate defect states. Our results show that NO an...

journal_title：Scientific reports

authors： Huang Y,Ma T,Chen QY,Cao C,He Y

更新日期：2015-08-03 00:00:00

abstract：:Epithelial-mesenchymal transition (EMT) plays an important role in aggravating invasiveness and metastatic behavior of colorectal cancer (CRC). Identification of EMT is important for structuring treatment strategy, but has not yet been studied by using noninvasive imaging modality. Diffusion kurtosis imaging (DKI) is ...

journal_title：Scientific reports

authors： Liu H,Shen W,Zhang C,Cui Y,Li J,Zhang T,Chen W,Wang D

更新日期：2017-09-12 00:00:00

abstract：:Flavonoids, theanine and caffeine are the main secondary metabolites of the tea plant (Camellia sinensis), which account for the tea's unique flavor quality and health benefits. The biosynthesis pathways of these metabolites have been extensively studied at the transcriptional level, but the regulatory mechanisms are ...

journal_title：Scientific reports

authors： Qiao D,Yang C,Chen J,Guo Y,Li Y,Niu S,Cao K,Chen Z

更新日期：2019-02-25 00:00:00

abstract：:TiO2 nanoribbons (TiO2 NRs) loaded with FeCo-Al2O3 catalyst were synthesized and used as a precursor in the synthesis of TiO2 nanoribbons/carbon nanotubes (TiO2 NRs/CNTs) composite by a chemical vapor deposition (CVD) method. TiO2 NRs and TiO2 NRs/CNTs composite were characterized by XRD, FT-IR, TEM, SEM, EDX and UV-V...

journal_title：Scientific reports

authors： Shaban M,Ashraf AM,Abukhadra MR

更新日期：2018-01-15 00:00:00

abstract：:Multishelled NiO hollow microspheres for high-performance supercapacitors have been prepared and the formation mechanism has been investigated. By using resin microspheres to absorb Ni(2+) and subsequent proper calcinations, the shell numbers, shell spacing and exterior shell structure were facilely controlled via var...

journal_title：Scientific reports

authors： Qi X,Zheng W,Li X,He G

更新日期：2016-09-12 00:00:00

abstract：:Comprehensive and accurate characterization of brain metabolome is fundamental to brain science, but has been hindered by technical limitations. We profiled the brain metabolome in male Wistar rats at different ages (day 1 to week 111) using high-sensitivity and high-resolution mass spectrometry. Totally 380 metabolit...

journal_title：Scientific reports

authors： Zheng X,Chen T,Zhao A,Wang X,Xie G,Huang F,Liu J,Zhao Q,Wang S,Wang C,Zhou M,Panee J,He Z,Jia W

更新日期：2016-04-11 00:00:00

abstract：:Silver nanobelts (AgNBs) have attracted a great interest due to their excellent electrical conductivity and mechanical strength, leading a facile synthesis of these AgNBs in great demand. In here, we are reporting a simple, aqueous phase, size tunable synthesis of smooth surfaced 1D-silver nanobelts using a Polyanilin...

journal_title：Scientific reports

authors： Padmanaban S,Kim M,Yoon S

更新日期：2017-03-20 00:00:00

abstract：:Materials with a layered structure have attracted tremendous attention because of their unique properties. The ultrathin nanosheet structure can result in extremely rapid intercalation/de-intercalation of Na ions in the charge-discharge progress. Herein, we report a manganese oxide with pre-intercalated K and Na ions ...

journal_title：Scientific reports

authors： Feng M,Du Q,Su L,Zhang G,Wang G,Ma Z,Gao W,Qin X,Shao G

更新日期：2017-05-22 00:00:00

abstract：:Recognising an object involves rapid visual processing and activation of semantic knowledge about the object, but how visual processing activates and interacts with semantic representations remains unclear. Cognitive neuroscience research has shown that while visual processing involves posterior regions along the vent...

journal_title：Scientific reports

authors： Devereux BJ,Clarke A,Tyler LK

更新日期：2018-07-13 00:00:00

abstract：:Interleukin (IL) 16 plays a key role in inflammatory diseases as well as in tumorigenesis of osteosarcoma (OS). The aim of this study was to investigate the association of IL16 polymorphisms and plasma IL16 level with OS risk in a Chinese population. We genotyped IL16 rs4778889, rs11556218, and rs4072111 in 358 patien...

journal_title：Scientific reports

authors： Tang YJ,Wang JL,Xie KG,Lan CG

更新日期：2016-10-05 00:00:00

abstract：:This study investigated a rabbit model of autologous simple oral mucosal epithelium transplantation (SOMET) for limbal stem cell deficiency (LSCD). LSCD was created in the SOMET group and the Control group. In the SOMET group, oral mucosa harvested from the buccal region was treated with dispase, cut into small pieces...

journal_title：Scientific reports

authors： Inamochi A,Tomioka A,Kitamoto K,Miyai T,Usui T,Aihara M,Yamagami S

更新日期：2019-12-02 00:00:00

abstract：:Hearing loss resulting from hair cell degeneration is a common disease that affects millions of people worldwide. Strategies to overcome the apparent irreversible hair cell loss in mammals become paramount for hearing protection. Here we reported that, by using a well-established gentamicin-induced hair cell loss mode...

journal_title：Scientific reports

authors： Quan Y,Xia L,Shao J,Yin S,Cheng CY,Xia W,Gao WQ

更新日期：2015-02-02 00:00:00

abstract：:Real-time impairment of ocular blood flow (OBF) under common carotid artery stenosis (CCAS) has not been ascertained. We aimed to longitudinally assess the impact of CCAS on OBF using a rabbit model. About 75% stenosis was created by tying the common carotid artery with a plastic mandrel using a nylon suture. The plas...

journal_title：Scientific reports

authors： Ismail A,Chen HC,Faye I,Tang TB

更新日期：2020-09-28 00:00:00

abstract：:Jute fibre is the second most important fibre next to cotton. It is obtained from the bark of plant through microbial retting process. Here we report optimized microbial retting protocol that can lower retting period and produce high fibre quality. A total of 451 bacterial colonies have been isolated from five jute re...

journal_title：Scientific reports

authors： Hasan R,Aktar N,Kabir SMT,Honi U,Halim A,Islam R,Sarker MDH,Haque MS,Alam MM,Islam MS

更新日期：2020-03-20 00:00:00

abstract：:Mountain ecosystems serve as sentinels of change, and those in the Canadian Rocky Mountains have undergone a pronounced shift over the past century. We present quantitative analyses of 81 high-resolution image pairs of systematic historic surveys and repeat photographs of Canadian Rocky Mountain habitats, measuring tr...

journal_title：Scientific reports

authors： Trant A,Higgs E,Starzomski BM

更新日期：2020-06-16 00:00:00

abstract：:We study the driven translocation of a semi-flexible polymer through a nanopore by means of a modified version of the iso-flux tension propagation theory, and extensive molecular dynamics (MD) simulations. We show that in contrast to fully flexible chains, for semi-flexible polymers with a finite persistence length [F...

journal_title：Scientific reports

authors： Sarabadani J,Ikonen T,Mökkönen H,Ala-Nissila T,Carson S,Wanunu M

更新日期：2017-08-07 00:00:00

abstract：:Although most of the near non-equilibrium microstructures of alloys produced by laser powder bed fusion (LPBF) additive manufacturing (AM) are being reported at a rapid rate, the accountable thermokinetics of the entire process have rarely been studied. In order to exploit the versatility of this AM process for the de...

journal_title：Scientific reports

authors： Pantawane MV,Ho YH,Joshi SS,Dahotre NB

更新日期：2020-05-05 00:00:00

abstract：:MicroRNA is responsible for the fine-tuning of fundamental cellular activities and human disease development. The altered availability of microRNAs, target mRNAs, and other types of endogenous RNAs competing for microRNA interactions reflects the dynamic and conditional property of microRNA-mediated gene regulation th...

journal_title：Scientific reports

authors： Shu J,Silva BVRE,Gao T,Xu Z,Cui J

更新日期：2017-10-17 00:00:00

abstract：:Evolution of resistance threatens sustainability of transgenic crops producing insecticidal proteins from the bacterium Bacillus thuringiensis (Bt). The fall armyworm (Spodoptera frugiperda) is a devastating pest of corn in the Western Hemisphere initially controlled by transgenic Bt corn producing the Cry1Fa insectic...

journal_title：Scientific reports

authors： Banerjee R,Hasler J,Meagher R,Nagoshi R,Hietala L,Huang F,Narva K,Jurat-Fuentes JL

更新日期：2017-09-07 00:00:00

abstract：:Carbon dioxide supercritical fluid extraction (CO2 SFE) is a clean and cost-effective method of extracting cannabinoids from cannabis. Using design of experiment methodologies an optimised protocol for extraction of medicinal cannabis bud material (population of mixed plants, combined THC:CBD approximately 1:1.5) was ...

journal_title：Scientific reports

authors： Rochfort S,Isbel A,Ezernieks V,Elkins A,Vincent D,Deseo MA,Spangenberg GC

更新日期：2020-06-04 00:00:00

abstract：:Recent advances in next-generation sequencing technologies have paved the path for a considerable amount of sequencing data at a relatively low cost. This has revolutionized the genomics and transcriptomics studies. However, different challenges are now created in handling such data with available bioinformatics platf...

journal_title：Scientific reports

authors： Naranpanawa DNU,Chandrasekara CHWMRB,Bandaranayake PCG,Bandaranayake AU

更新日期：2020-10-26 00:00:00

abstract：:Supported by histological and genetic evidence implicating myelin, neuroinflammation and oligodendrocyte dysfunction in schizophrenia spectrum disorders (SZ), diffusion tensor imaging (DTI) studies have consistently shown white matter (WM) abnormalities when compared to healthy controls (HC). The diagnostic specificit...

journal_title：Scientific reports

authors： Tønnesen S,Kaufmann T,Doan NT,Alnæs D,Córdova-Palomera A,Meer DV,Rokicki J,Moberget T,Gurholt TP,Haukvik UK,Ueland T,Lagerberg TV,Agartz I,Andreassen OA,Westlye LT

更新日期：2018-09-20 00:00:00