A resource for cell line authentication, annotation and quality control.

Abstract:

:Cell line misidentification, contamination and poor annotation affect scientific reproducibility. Here we outline simple measures to detect or avoid cross-contamination, present a framework for cell line annotation linked to short tandem repeat and single nucleotide polymorphism profiles, and provide a catalogue of synonymous cell lines. This resource will enable our community to eradicate the use of misidentified lines and generate credible cell-based data.

journal_name

Nature

journal_title

Nature

authors

Yu M,Selvaraj SK,Liang-Chu MM,Aghajani S,Busse M,Yuan J,Lee G,Peale F,Klijn C,Bourgon R,Kaminker JS,Neve RM

doi

10.1038/nature14397

subject

Has Abstract

pub_date

2015-04-16 00:00:00

pages

307-11

issue

7547

eissn

0028-0836

issn

1476-4687

pii

nature14397

journal_volume

520

pub_type

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