Abstract:
:Cell line misidentification, contamination and poor annotation affect scientific reproducibility. Here we outline simple measures to detect or avoid cross-contamination, present a framework for cell line annotation linked to short tandem repeat and single nucleotide polymorphism profiles, and provide a catalogue of synonymous cell lines. This resource will enable our community to eradicate the use of misidentified lines and generate credible cell-based data.
journal_name
Naturejournal_title
Natureauthors
Yu M,Selvaraj SK,Liang-Chu MM,Aghajani S,Busse M,Yuan J,Lee G,Peale F,Klijn C,Bourgon R,Kaminker JS,Neve RMdoi
10.1038/nature14397subject
Has Abstractpub_date
2015-04-16 00:00:00pages
307-11issue
7547eissn
0028-0836issn
1476-4687pii
nature14397journal_volume
520pub_type
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