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A noisy tug of war: the battle between transcript production and degradation in the liver.

Abstract：

:Genetically identical cells in culture often exhibit significant variations, or noise, in gene expression, largely due to transcriptional bursting. Halpern et al. (2015) have developed methods to study gene bursting in tissues to find that this transcriptional bursting also occurs in the mammalian liver and may contribute to functional plasticity in hepatocytes.

journal_name

Dev Cell

journal_title

Developmental cell

authors

Lam A,Deans TL

doi

10.1016/j.devcel.2015.03.019

subject

Has Abstract

pub_date

2015-04-06 00:00:00

pages

3-4

issue

1

eissn

1534-5807

issn

1878-1551

pii

S1534-5807(15)00215-4

journal_volume

33

pub_type

评论,杂志文章

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