Infection homeostasis: implications for therapeutic and immune programming of metabolism in controlling infection.

abstract：:The Enders strain of mumps virus grown in ovo was purified by differential and equilibrium sucrose gradient sedimentation. Purified virus contained seven polypeptides of mol. wts 68,000, 66,000, 61,000, 54,000, 52,000, 49,000, 47,000. Nucleocapsids isolated from DOC-treated virus contained two polypeptides of mol. wts...

journal_title：Medical microbiology and immunology

authors： Huppertz HI,Hall WW,ter Meulen V

更新日期：1977-12-27 00:00:00

abstract：:A sentinel surveillance system of the public health service for acute respiratory diseases (ARD), especially influenza, has been realized in the Free State of Saxony of Germany for 25 years. The epidemiological sentinel is based on weekly registration of morbidity and mathematical-statistical calculations. For a micro...

journal_title：Medical microbiology and immunology

authors： Bigl S,Briem I,Drechsler R,Kluge D,Müller L,Nowotnik G

更新日期：2002-12-01 00:00:00

abstract：:Pteridine derivatives neopterin and 7,8-dihydroneopterin are produced by human macrophages and dendritic cells upon stimulation with interferon-gamma (IFN-gamma) and therefore become detectable in increased amounts in humans during cell-mediated (Th1-type) immune response. Compounds produced upon influence of cytokine...

journal_title：Medical microbiology and immunology

authors： Bratslavska O,Platace D,Miklasevics E,Fuchs D,Martinsons A

更新日期：2007-03-01 00:00:00

abstract：:Vaccination has proven to be one of the best weapons protecting the mankind against infectious diseases. Along with the huge progress in microbiology, numerous highly efficacious and safe vaccines have been produced by conventional technology (cultivation), by the use of molecular biology (genetic modification), or by...

journal_title：Medical microbiology and immunology

authors： Doerr HW,Berger A

更新日期：2014-12-01 00:00:00

abstract：:In a randomized, placebo-controlled trial in Ghana, 67 onchocerciasis patients received 200-mg/day doxycycline for 4-6 weeks, followed by ivermectin (IVM) after 6 months. After 6-27 months, efficacy was evaluated by onchocercoma histology, PCR and microfilariae determination. Administration of doxycycline resulted in ...

journal_title：Medical microbiology and immunology

authors： Hoerauf A,Specht S,Büttner M,Pfarr K,Mand S,Fimmers R,Marfo-Debrekyei Y,Konadu P,Debrah AY,Bandi C,Brattig N,Albers A,Larbi J,Batsa L,Taylor MJ,Adjei O,Büttner DW

更新日期：2008-09-01 00:00:00

abstract：:Several lines of evidence suggest a viral infection as the initiating event for the development of myocarditis (MC). Especially enteroviruses like coxsackie B3 virus have been shown to induce MC in humans and strains of MC-prone mice after an infection. The further course of the disease is, however, determined not onl...

journal_title：Medical microbiology and immunology

authors： Schwimmbeck PL,Bigalke B,Schulze K,Pauschinger M,Kühl U,Schultheiss HP

更新日期：2004-05-01 00:00:00

abstract：:Tests were made on 169 sera from children up to 10 years of age for rotavirus antibodies by indirect immunofluorescence and complement fixation tests. The simian strain SA 11 served as a substitute antigen for the human rotavirus. Furthermore, the SA 11 complement-fixing antigen was compared with a commercial antigen ...

journal_title：Medical microbiology and immunology

authors： Brade L,Schmidt WA

更新日期：1979-03-13 00:00:00

abstract：:The present study describes the respiratory immune response of mice to locally administered antigen, and the modulation of this response by systemic immunization. Intranasal immunization of mice with the A/PR/8/34 strain of influenza virus evoked local antibody response of the IgA type. The titer of the IgA antibodies...

journal_title：Medical microbiology and immunology

authors： Zakay-Rones Z,Hadas O,Levy R

更新日期：1978-11-17 00:00:00

abstract：:The aim of this study was to characterize the cytokine secretion patterns of human T helper cells from healthy donors reactive with somatic antigens from various bacteria, the nematode Anisakis and tetanus toxoid. From the peripheral blood of four healthy donors we have established 70 T cell lines reactive with antige...

journal_title：Medical microbiology and immunology

authors： Schlaak JF,Nieder P,Meyer zum Büschenfelde KH,Fleischer B

更新日期：1994-07-01 00:00:00

abstract：:A total of 603 serum samples obtained from 12 different patient and control groups, including potentially cross-reactive sera, were tested for the presence of antibodies against Kaposi's sarcoma-associated herpesvirus (KSHV, HHV-8). The assays used were an inhouse immunofluorescence test (IFT) employing latent KSHV an...

journal_title：Medical microbiology and immunology

authors： Preiser W,Szép NI,Lang D,Doerr HW,Rabenau HF

更新日期：2001-12-01 00:00:00

abstract：:We previously reported that Trypanosoma cruzi, the agent of Chagas disease, induces in congenitally infected fetuses a strong, adult-like parasite-specific CD8(+) T cell response producing IFN-γ (Hermann et al. in Blood 100:2153-2158, 2002). This suggests that the parasite is able to overcome the immaturity of neonata...

journal_title：Medical microbiology and immunology

authors： Rodriguez P,Carlier Y,Truyens C

更新日期：2012-05-01 00:00:00

abstract：:The propagation of hepatitis A virus (HAV) is shown in a rapidly growing fetal rhesus monkey kidney cell line (Frhk-4/R). In the course of ten passages through Frhk-4/R cells the HAV, which was released in the supernatants of the cell cultures, was adapted to these cells. In the tenth passage 6 days after infection, i...

journal_title：Medical microbiology and immunology

authors： Flehmig B

更新日期：1981-01-01 00:00:00

abstract：:In resource-limited or point-of-care settings, rapid diagnostic tests (RDTs), that aim to simultaneously detect HIV antibodies and p24 capsid (p24CA) antigen with high sensitivity, can pose important alternatives to screen for early infections. We evaluated the performance of the antibody and antigen components of the...

journal_title：Medical microbiology and immunology

authors： Wratil PR,Rabenau HF,Eberle J,Stern M,Münchhoff M,Friedrichs I,Stürmer M,Berger A,Kuttner-May S,Münstermann D,Lucht A,Meixenberger K,Bannert N,Keppler OT

更新日期：2020-04-01 00:00:00

abstract：:Illness and death of mice infected by intracerebral inoculation with lymphocytic choriomeningitis virus are pathologic immune phenomena, and mice thus infected were protected when immunosuppressed with cyclosporin A (CSA), although the virus multiplied extensively in all major organs. Concentrations remained high as l...

journal_title：Medical microbiology and immunology

authors： Löliger C,Lehmann-Grube F

更新日期：1985-01-01 00:00:00

abstract：:Mycobacterium avium subsp. paratuberculosis (MAP) has long been implicated as a triggering agent in Crohn's disease (CD). In this study, we investigated the growth/persistence of both M. avium subsp. hominissuis (MAH) and MAP, in macrophages from healthy controls (HC), CD and ulcerative colitis patients. For viability...

journal_title：Medical microbiology and immunology

authors： Nazareth N,Magro F,Appelberg R,Silva J,Gracio D,Coelho R,Cabral JM,Abreu C,Macedo G,Bull TJ,Sarmento A

更新日期：2015-12-01 00:00:00

abstract：:CAMP factor is an extracellular cytolytic protein produced by Streptococcus agalactiae. CAMP factor has been reported to bind the Fc fragments of immunoglobulin G (IgG) and has therefore also been called protein B, in analogy to protein A of Staphylococcus aureus. We attempted to characterize the interaction of protei...

journal_title：Medical microbiology and immunology

authors： El-Huneidi W,Mui R,Zhang TH,Palmer M

更新日期：2007-06-01 00:00:00

abstract：:IgG subclass antibodies to Pseudomonas aeruginosa outer membrane proteins (OMP) were investigated in serum from cystic fibrosis (CF) patients by immunoblotting and enzyme-linked immunosorbent assay (ELISA). Fifteen patients (eight in good and seven in poor clinical condition) have been followed for an average of 13 ye...

journal_title：Medical microbiology and immunology

authors： Pressler T,Kronborg G,Shand GH,Mansa B,Høiby N

更新日期：1992-01-01 00:00:00

abstract：:The stimulatory effect of lipopolysaccharide (LPS) on human macrophages was found to be neutralized by the detergent octylglucoside (OG). Both macrophage stimulation and reactivity in a limulus amebocyte lysate test were suppressed by suspension of LPS in OG at concentrations between 0.25 and 2.5 mM, whereas other sti...

journal_title：Medical microbiology and immunology

authors： Henrich B,Guadarrama R,Zähringer U,MacKenzie CR

更新日期：2001-04-01 00:00:00

abstract：:Interactions of virulent Leptospira interrogans with murine monocyte-macrophage-like J774A.1 cells and Vero (African green monkey kidney fibroblasts) cells from attachment to internalization were investigated by a series of morphological analysis. Fontana silver staining revealed that only the pathogenic leptospires w...

journal_title：Medical microbiology and immunology

authors： Liu Y,Zheng W,Li L,Mao Y,Yan J

更新日期：2007-12-01 00:00:00

abstract：:Burkholderia pseudomallei, a gram-negative intracellular bacterium, is a causative agent of melioidosis. The bacterium has been shown to induce the innate immune response, particularly pro-inflammatory cytokine production in several of both mouse and human cell types. In the present study, we investigate host immune r...

journal_title：Medical microbiology and immunology

authors： Kulsantiwong P,Pudla M,Boondit J,Wikraiphat C,Dunachie SJ,Chantratita N,Utaisincharoen P

更新日期：2016-06-01 00:00:00

abstract：:A set of 12 rapid biochemical tests--lysinedecarboxylase, ornithinedecarboxylase, beta-galactosidase, urease, hydrogensulphide, indole, acetoin, deoxyribonuclease, esculin, mannitol, raffinose and sorbitol--were selected from an original set of 13 tests and were found to give 98% accurate reactions within 4 hrs of inc...

journal_title：Medical microbiology and immunology

authors： Nord C-E,Linberg AA,Dahlbäck A

更新日期：1975-09-19 00:00:00

abstract：:The new QuantiFERON-TB Gold Plus employs modified peptides optimized to elicit an IFNγ response from CD8+ cytotoxic T lymphocytes in addition to CD4+ T cells. With a view to improve the difficult identification of TB cases, we assessed the combination of two specific immunological markers comprising IFNγ secretion and...

journal_title：Medical microbiology and immunology

authors： Sauzullo I,Mengoni F,Mascia C,Pavone P,Savelloni G,Massetti AP,Lichtner M,Vullo V,Mastroianni CM

更新日期：2019-04-01 00:00:00

abstract：:Various strains of Helicobacter pylori were able to lyse erythrocytes from sheep, horse, and human when grown on blood agar. The hemolysis did not depend on the production of the vacuolating cytotoxin VacA as demonstrated by the hemolytic behavior of an isogenic vacA-negative mutant strain. The hemolytic activity coul...

journal_title：Medical microbiology and immunology

authors： Bereswill S,Fassbinder F,Völzing C,Covacci A,Haas R,Kist M

更新日期：1998-03-01 00:00:00

abstract：:IFN-γ release assays (IGRAs) often present false-negative or indeterminate results in children with tuberculosis. HIV co-infection may contribute to decreased sensitivity of IGRAs by impairing T-cell IFN-γ expression. Measurement of alternative cytokines in QuantiFERON® (QFT) supernatants can circumvent the IFN-γ-depe...

journal_title：Medical microbiology and immunology

authors： Lundtoft C,Awuah AA,Nausch N,Enimil A,Mayatepek E,Owusu-Dabo E,Jacobsen M

更新日期：2017-06-01 00:00:00

abstract：:A microcytoxicity assay with 3H-proline prelabeled target cells was used for the detection of sensitized lymphoid spleen cells from STU inbred mice inoculated with Moloney sarcoma virus (MSV-M) or ascitic MSV-M tumor cells. The target cell line was derived from ascitic MSV-M tumor cells. With regard to the specificity...

journal_title：Medical microbiology and immunology

authors： Weiland E,Mussgay M

更新日期：1976-06-01 00:00:00

abstract：:This study describes the properties of an inactivated subunit antigen preparation from varicella-zoster virus (VZV)-infected MRC-5 cells by treatment with detergent and formaldehyde, ultracentrifugation over sucrose and acetone precipitation. The method preserved the antigenicity of VZV proteins and several VZV-specif...

journal_title：Medical microbiology and immunology

authors： Davies J,Hallworth JA,McLeish P,Randall S,Martin BA,Buchan A,Skinner GR

更新日期：1994-05-01 00:00:00

abstract：:Cytomegalovirus vaccine development started in the 1970s with attenuated strains. In the 1980s, one of the strains was shown to be safe and effective in renal transplant patients. Then, attention switched to glycoprotein gB, which was shown to give moderate but transient protection against acquisition of the virus by ...

journal_title：Medical microbiology and immunology

authors： Plotkin S

更新日期：2015-06-01 00:00:00

abstract：:The antiviral activity of mouse fibroblast interferon against vesicular stomatitis virus was investigated in L-929 mouse fibroblasts and the ganglioside-deficient L-929 mutant cells (ATCC clone NCTC 2071). Although it has been widely reported that gangliosides serve as primary receptors for interferon at the cellular ...

journal_title：Medical microbiology and immunology

authors： Schiffmann D,Koschel K

更新日期：1981-01-01 00:00:00

abstract：:Cytomegaloviruses (CMVs) are large double-stranded DNA viruses that replicate slowly and cause life-long persisting infections in their hosts. To achieve this, the CMVs had to evolve numerous countermeasures against innate and adaptive immune responses. Induction of programmed cell death is one important host defense ...

journal_title：Medical microbiology and immunology

authors： Handke W,Krause E,Brune W

更新日期：2012-11-01 00:00:00

abstract：:The influenza surveillance in Lower Saxony is based mainly on laboratory investigations, and especially those which involve the isolation of influenza viruses throughout the year. These investigations have provided information on the circulation of influenza viruses and of the antigenic drift during the Hong Kong peri...

journal_title：Medical microbiology and immunology

authors： Willers H,Höpken W

更新日期：1979-03-13 00:00:00