Abstract:
:Vaccination has proven to be one of the best weapons protecting the mankind against infectious diseases. Along with the huge progress in microbiology, numerous highly efficacious and safe vaccines have been produced by conventional technology (cultivation), by the use of molecular biology (genetic modification), or by synthetic chemistry. Sterilising prevention is achieved by the stimulation of antibody production, while the stimulation of cell-mediated immune responses may prevent the outbreak of disease in consequence of an acute or reactivated infection. From several examples, two rules are deduced to evaluate the perspectives of future vaccine developments: They are promising, if (1) the natural infectious disease induces immunity or (2) passive immunisation (transfer of antibodies, adoptive transfer of lymphocytes) is successful in preventing infection.
journal_name
Med Microbiol Immunoljournal_title
Medical microbiology and immunologyauthors
Doerr HW,Berger Adoi
10.1007/s00430-014-0346-1subject
Has Abstractpub_date
2014-12-01 00:00:00pages
365-71issue
6eissn
0300-8584issn
1432-1831journal_volume
203pub_type
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