Abstract:
:The antiviral activity of mouse fibroblast interferon against vesicular stomatitis virus was investigated in L-929 mouse fibroblasts and the ganglioside-deficient L-929 mutant cells (ATCC clone NCTC 2071). Although it has been widely reported that gangliosides serve as primary receptors for interferon at the cellular membrane, only a small difference in interferon sensitivity was observed between the wild-type L-929 and the ganglioside-deficient NCTC 2071 cells. It was not possible, however, to overcome this difference by administration of exogenous gangliosides.
journal_name
Med Microbiol Immunoljournal_title
Medical microbiology and immunologyauthors
Schiffmann D,Koschel Kdoi
10.1007/BF02125527subject
Has Abstractpub_date
1981-01-01 00:00:00pages
281-9issue
4eissn
0300-8584issn
1432-1831journal_volume
169pub_type
杂志文章abstract::Human cytomegalovirus (HCMV) infection modulates the host cell cycle to create an environment that is optimal for viral gene expression, DNA replication, and production of infectious virus. The virus mostly infects quiescent cells and thus must push the cell into G1 phase of the cell cycle to co-opt the cellular mecha...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章,评审
doi:10.1007/s00430-015-0396-z
更新日期:2015-06-01 00:00:00
abstract::Lactoferrin (Lf) is an iron-binding protein which plays an important role in the host defense systems of different mucosal surfaces including the intestinal mucosa. In the present research the role of apo-Lf and iron-saturated Lf in the invasion process of enteroinvasive bacteria, grown in iron stress or excess, was i...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/BF00195948
更新日期:1993-03-01 00:00:00
abstract::Lack of virus-specific cell-mediated immunity (CMI) is associated with worse viral infection outcome in hematopoietic stem cell transplantation (HSCT). We aimed to evaluate the role of immunological monitoring of Epstein-Barr virus (EBV) infection in addition to virological one in 33 adult and 18 pediatric allogeneic ...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/s00430-019-00629-2
更新日期:2019-12-01 00:00:00
abstract::The pathogenesis of Staphylococcus aureus from local infection to systemic dissemination involves a range of virulence factors including structural and secreted products. Among various control mechanisms, small noncoding RNAs are involved in the regulation of multiple pathogenicity factors in S. aureus. The sRNA SprX ...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/s00430-016-0467-9
更新日期:2016-12-01 00:00:00
abstract::In the present study, synthetic peptides (EENVEHDA)2 [(oc)2] and (DDEHVEEPTVA)2 [(un)2] of ring-infected erythrocyte surface antigen (RESA) of Plasmodlium filciparum were linked with palmitic acid and entrapped in immunostimulating complexes (ISCOMs). The immunogenicity of the peptide(s) and mixture of peptides were s...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/s004300000042
更新日期:2000-11-01 00:00:00
abstract::Oral treatment of mice with a combination of non-absorbable broad spectrum antibiotics at a dose level high enough to sterilize the digestive tract within five days of treatment, has been found to have a significant negative effect on the relative weight of the thymus. From the age of 12 weeks onwards, the mean relati...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/BF02123870
更新日期:1986-01-01 00:00:00
abstract::Burkholderia pseudomallei, a gram-negative intracellular bacterium, is a causative agent of melioidosis. The bacterium has been shown to induce the innate immune response, particularly pro-inflammatory cytokine production in several of both mouse and human cell types. In the present study, we investigate host immune r...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/s00430-015-0440-z
更新日期:2016-06-01 00:00:00
abstract::Antibodies against the human coronavirus OC43 in human sera were measured by haemagglutination inhibition (HI), complement fixation (CF), and radial diffusion-haemolysis in gel (HIG) techniques. The apparent HI titres in a fraction of sera with no antibodies detectable by the two other methods were found to be reduced...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/BF02121147
更新日期:1978-11-17 00:00:00
abstract::IgG immune response to CagA was evaluated by enzyme-linked imunosorbent assay (ELISA) using a recombinant fragment of CagA as antigen in 171 patients with gastric cancer and 298 blood donors to determine whether it could be related to the ABO(H) blood group phenotype, stage of cancer or tumor morphology. The CagA-ELIS...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/s004300050097
更新日期:1999-05-01 00:00:00
abstract::Tetraspanin (TSPAN) protein family forms a family of transmembrane proteins that act as organizers/scaffold for other proteins. TSPANs are primarily present on plasma membranes although they are also found in other biological membranes. They are organized in tetraspanin-enriched microdomains (TEMs), which allow spatio...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章,评审
doi:10.1007/s00430-020-00681-3
更新日期:2020-08-01 00:00:00
abstract::Surface proteins of nine Campylobacter jejuni strains belonging to three different serovia were extracted with lysozyme/ethylenediamine-tetraacetic acid. The preparations bound to isolated murine small intestinal cells and to a membrane fraction (MF) of isolated brush borders obtained by detergent treatment with Trito...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/BF00202555
更新日期:1989-01-01 00:00:00
abstract::IgG subclass antibodies to Pseudomonas aeruginosa outer membrane proteins (OMP) were investigated in serum from cystic fibrosis (CF) patients by immunoblotting and enzyme-linked immunosorbent assay (ELISA). Fifteen patients (eight in good and seven in poor clinical condition) have been followed for an average of 13 ye...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/BF00191546
更新日期:1992-01-01 00:00:00
abstract::The streptococcal pyrogenic exotoxin B (SpeB) is known to be involved in group A streptococcus (GAS) survival in blood, but the detailed mechanism is not clear. For clarification of this issue, speB isogenic mutants of strains M6 and M49 were constructed by using an integrational plasmid and confirmed by Southern blot...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/s00430-005-0001-y
更新日期:2006-06-01 00:00:00
abstract::Low public awareness of cytomegalovirus (CMV) results from the only mild and transient symptoms that it causes in the healthy immunocompetent host, so that primary infection usually goes unnoticed. The virus is not cleared, however, but stays for the lifetime of the host in a non-infectious, replicatively dormant stat...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章,评审
doi:10.1007/s00430-012-0273-y
更新日期:2012-11-01 00:00:00
abstract::9 antigen distribution and sensitivity to the bactericidal effect of normal human serum were determined in 485 Proteus strains isolated from urine, blood, wounds, and feces. Of all strains, 62% could be grouped according to 25 0 antigens. The most frequent one, 0 3, appeared in 13% of all the strains. In blood culture...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/BF02121822
更新日期:1977-07-18 00:00:00
abstract::NFR nude (nu/nu) and euthymic (+/nu) littermates were infected with coxsackievirus B3 (CBV-3) and assayed for virus persistence in the heart, pancreas and spleen, for development of myocarditis and for antibody production. The virus grew to higher titer and persisted longer in hearts of nu/nu mice. In both types of mi...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/BF02123563
更新日期:1984-01-01 00:00:00
abstract::TT virus (TTV) is a newly discovered virus from a patient with post-transfusion hepatitis. We investigated the frequency and pathogenesis of TTV infection in children. A semi-nested PCR assay was used to amplify TTV-DNA in serum samples from 254 ambulatory children without liver disease, 20 with hepatitis of unknown e...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/s004300050109
更新日期:1999-11-01 00:00:00
abstract::Quorum sensing system is a cell-to-cell communication system that plays a pivotal role in virulence expression in bacteria. Recent advances have demonstrated that the Pseudomonas aeruginosa quorum sensing molecule, N-3-oxododecanoyl homoserine lactone (3OC(12)-HSL), exerts effects on mammalian cells and modulates host...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/s00430-009-0111-z
更新日期:2009-05-01 00:00:00
abstract::The effect of immune bovine lactoserum (BLS) antipolyvalent enteropathogenic Escherichia coli on bacterial growth, viability and bacteria-induced fluid accumulation was examined in rabbit ileal loops. Human enteropathogenic E. coli strains 0125:K70 (B15), 0111:K58 (B4) and 055:K59 (B5) (1-3 X 10(9) per inoculum) induc...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/BF02123571
更新日期:1975-12-30 00:00:00
abstract::The improved Auxotab Enteric I System was re-evaluated and found to correlate 98% with conventional methods for the identification of Enterobacteriaceae. Possible Reasons for previous poor results with this system are discussed. ...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/BF02121009
更新日期:1975-07-02 00:00:00
abstract::A new way of measuring indirect immunofluorescence (IIF) of microscopic bacterial slide preparations by videocamera and an image processing system is presented. This method is compared with the conventional method of reading the slides by eye. The advantages of this new approach are objective reading, greater accuracy...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/BF00193850
更新日期:1991-01-01 00:00:00
abstract::While the antigen structure of yeast cell walls is well known, the immunological cross reactivity of these is often difficult to interpret. The cross reactions of eight yeasts were tested in rabbit hyperimmune sera by the indirect immunofluorescence test. Among the eight species examined were the medically important y...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/BF02120806
更新日期:1979-01-01 00:00:00
abstract::A total of 114 Clostridium difficile strains were analysed for a possible correlation between serological susceptibility to chloramphenicol, tetracycline and clindamycin, and serogrouping. All 17 chloramphenicol-resistant strains belonged to serovar I, while none of 32 tetracycline-resistant strains belonged to serova...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/BF00200678
更新日期:1987-01-01 00:00:00
abstract::Turkey is seeing a steady rise in rates of HIV infection in the country. The number of individuals with HIV/AIDS was greater than 7000 in 2014 according to data released by the Ministry of Health, and heterosexual contacts were reported to be the main transmission routes. Istanbul has the highest number of reported ca...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/s00430-015-0419-9
更新日期:2015-08-01 00:00:00
abstract::The avirulent Salmonella typhimurium galE strain G30, following oral feeding to mice, developed a state of immunity to a secondary oral challenge with virulent Salmonella typhimurium. This immunity was concommitant with the development of intestinal and serum antibodies and delayed-type hyepersensitivity (DTH) to Salm...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/BF02121760
更新日期:1980-01-01 00:00:00
abstract::A 33-kDa protein (TB33) was isolated from a delipidated cell sonicate (CS) of Mycobacterium tuberculosis H37Rv (grown in Middlebrook 7H9 broth supplemented with glucose) using immobilized metal affinity chromatography (IMAC) on a nickel-nitrilotriacetic acid (Ni-NTA) column. TB33 could not be isolated from the culture...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/s004300050025
更新日期:1996-11-01 00:00:00
abstract::The efficiency was examined of immunization with feline leukemia virus glycoprotein complexes (gp85 rosettes) to protect cats against tumors induced by feline sarcoma virus (FeSV). The glycoprotein was isolated from feline leukemia virus (FeLV). Young cats were vaccinated with the purified viral glycoprotein and chall...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/BF02123497
更新日期:1983-01-01 00:00:00
abstract::Illness and death of mice infected by intracerebral inoculation with lymphocytic choriomeningitis virus are pathologic immune phenomena, and mice thus infected were protected when immunosuppressed with cyclosporin A (CSA), although the virus multiplied extensively in all major organs. Concentrations remained high as l...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/BF02123695
更新日期:1985-01-01 00:00:00
abstract::Leprosy is a chronic infectious disease caused by Mycobacterium leprae. Previous studies have demonstrated that the difference among clinical forms of leprosy can be associated with the immune response of patients, mainly by T helper (Th) and regulatory T cells (Tregs). Then, aiming at clarifying the immune response, ...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/s00430-017-0519-9
更新日期:2017-12-01 00:00:00
abstract::The present study was designed to determine whether tumor induction by 3-methylcholanthrene (MC), a carcinogenic hydrocarbon, can be inhibited by oral administration of Lactobacillus casei strain Shirota (LC). C3H/HeN mice were divided into four groups and assigned to the following treatments: treated with MC and give...
journal_title:Medical microbiology and immunology
pub_type: 杂志文章
doi:10.1007/s004300050112
更新日期:1999-12-01 00:00:00