Diagnostic performance in active TB of QFT-Plus assay and co-expression of CD25/CD134 in response to new antigens of Mycobacterium tuberculosis.

abstract：:This is a summary of the recent work on some glycosidases of sand flies and their Leishmania parasites. Glycosidases catalyze the hydrolysis of complex sugar subunits of polysaccharides into simple sugars. Leishmania major parasites secrete chitinase and N-acetylglucosaminase, which enables them to survive in the gut ...

journal_title：Medical microbiology and immunology

authors： Jacobson RL,Schlein Y,Eisenberger CL

更新日期：2001-11-01 00:00:00

abstract：:During normal interpandemic influenza seasons, immune responses to vaccines are quite predictable and meet the licensing criteria of the European Union (EU) Committee for Proprietary Medicinal Products (CPMP). In a pandemic situation, large sections, if not all of the community will be immunologically naïve and theref...

journal_title：Medical microbiology and immunology

authors： Wood JM,Nicholson KG,Stephenson I,Zambon M,Newman RW,Major DL,Podda A

更新日期：2002-12-01 00:00:00

abstract：:The development in rabbits of antibodies against common thermolabile Escherichia coli surface antigens - and against O and K antigens - was investigated. Three strains, E3b (O75:K95:H5), E56b (O8:K27:H-), and H61 (O45:K1:H10), and five rabbits per strain were used. Immunization was carried out by routine procedures us...

journal_title：Medical microbiology and immunology

authors： Orskov F,Larsen JC,Orskov I

更新日期：1981-01-01 00:00:00

abstract：:Almost 4000 sera from seven African states were examined for antibodies to ATLV/HTLV-1. Between 1% and 8% of healthy people from sub-Saharan Africa have such antibodies. The highest frequency was observed in Gabon. There were considerable variations between villages. The percentage of seropositives and the mean titre ...

journal_title：Medical microbiology and immunology

authors： Hunsmann G,Bayer H,Schneider J,Schmitz H,Kern P,Dietrich M,Büttner DW,Goudeau AM,Kulkarni G,Fleming AF

更新日期：1984-01-01 00:00:00

abstract：:Oral treatment of mice with a combination of non-absorbable broad spectrum antibiotics at a dose level high enough to sterilize the digestive tract within five days of treatment, has been found to have a significant negative effect on the relative weight of the thymus. From the age of 12 weeks onwards, the mean relati...

journal_title：Medical microbiology and immunology

authors： van der Waaij D

更新日期：1986-01-01 00:00:00

abstract：:Mycobacterium avium subsp. paratuberculosis (MAP) has long been implicated as a triggering agent in Crohn's disease (CD). In this study, we investigated the growth/persistence of both M. avium subsp. hominissuis (MAH) and MAP, in macrophages from healthy controls (HC), CD and ulcerative colitis patients. For viability...

journal_title：Medical microbiology and immunology

authors： Nazareth N,Magro F,Appelberg R,Silva J,Gracio D,Coelho R,Cabral JM,Abreu C,Macedo G,Bull TJ,Sarmento A

更新日期：2015-12-01 00:00:00

abstract：:Gliosis of glial fibrillary acidic protein (GFAP) associated astrocytes is considered to be one of the hallmarks of transmissible spongiform encephalopathies (TSEs). In the present study, remarkable GFAP-PrP(Sc) or GFAP-PrP(C) complexes were separately detected in the brain homogenates of 263 K (Scrapie)-infected or n...

journal_title：Medical microbiology and immunology

authors： Dong CF,Wang XF,Wang X,Shi S,Wang GR,Shan B,An R,Li XL,Zhang BY,Han J,Dong XP

更新日期：2008-12-01 00:00:00

abstract：:Neutrophil extracellular traps (NETs) have recently been discovered as a central part of antimicrobial innate immunity. In the meanwhile, evidence accumulated that NETs are also generated upon non-infectious stimuli in various clinical settings. In acute or chronic inflammatory disorders aberrantly enhanced NET format...

journal_title：Medical microbiology and immunology

authors： Lögters T,Margraf S,Altrichter J,Cinatl J,Mitzner S,Windolf J,Scholz M

更新日期：2009-11-01 00:00:00

abstract：:The infant rat model is widely used to study the pathogenesis of meningitis caused by a variety of gram-positive and gram-negative bacteria. However, the interpretation of published results concerning meningitis is difficult in many records because the fact that blood contamination of the cerebrospinal fluid (CSF) can...

journal_title：Medical microbiology and immunology

authors： Vogel U,Steinmetz I,Frosch M

更新日期：1996-05-01 00:00:00

abstract：:To characterize the role of specific lymphocyte subsets in Chlamydia trachomatis infection, we established a murine model using the mouse pneumonitis agent (MoPn) of C. trachomatis and C.B-17 scid/scid (SCID) mice which lack functional B and T cells. After intraperitoneal inoculation with the bacteria, SCID mice devel...

journal_title：Medical microbiology and immunology

authors： Thoma-Uszynski S,Simnacher U,Marre R,Essig A

更新日期：1998-10-01 00:00:00

abstract：:In this study, we presented the construction of a library of expression clones for the herpes simplex virus type 1 (HSV-1) proteome and subcellular localization map of HSV-1 proteins in living cells using yellow fluorescent protein (YFP) fusion proteins. As a result, 21 proteins showed cytoplasmic or subcytoplasmic lo...

journal_title：Medical microbiology and immunology

authors： Xing J,Wang S,Li Y,Guo H,Zhao L,Pan W,Lin F,Zhu H,Wang L,Li M,Wang L,Zheng C

更新日期：2011-02-01 00:00:00

abstract：:The administration of drugs to inhibit metabolic pathways not only reduces the risk of obesity-induced diseases in humans but may also hamper the replication of different viral pathogens. In order to investigate the value of the US Food and Drug Administration-approved anti-obesity drug orlistat in view of its anti-vi...

journal_title：Medical microbiology and immunology

authors： Ammer E,Nietzsche S,Rien C,Kühnl A,Mader T,Heller R,Sauerbrei A,Henke A

更新日期：2015-12-01 00:00:00

abstract：:The propagation of hepatitis A virus (HAV) is shown in a rapidly growing fetal rhesus monkey kidney cell line (Frhk-4/R). In the course of ten passages through Frhk-4/R cells the HAV, which was released in the supernatants of the cell cultures, was adapted to these cells. In the tenth passage 6 days after infection, i...

journal_title：Medical microbiology and immunology

authors： Flehmig B

更新日期：1981-01-01 00:00:00

abstract：:Carbapenems are important last-line antibiotics for the treatment of hospital infections. Enterobacteriaceae (such as Klebsiella pneumoniae or Escherichia coli) expressing the "New Delhi Metallo-β-lactamase" gene bla(NDM-1) are resistant to carbapenems and were predicted to become a major global health problem. To cop...

journal_title：Medical microbiology and immunology

authors： Krüttgen A,Razavi S,Imöhl M,Ritter K

更新日期：2011-05-01 00:00:00

abstract：:Proteus mirabilis (P. mirabilis), a gram-negative enteric bacterium, frequently causes urinary tract infections. Many virulence factors of uropathogenic P. mirabilis have been identified, including urease, flagella, hemolysin and fimbriae. However, the functions of polyphosphate kinase (PPK), which are related to the ...

journal_title：Medical microbiology and immunology

authors： Peng L,Jiang Q,Pan JY,Deng C,Yu JY,Wu XM,Huang SH,Deng XY

更新日期：2016-04-01 00:00:00

abstract：:The structural relation of YOP-1 of "european" and "american" Yersinia enterocolitica serotypes O:3, O:9, O:5,27, and O:8 and O:20, respectively, and Y. pseudotuberculosis serotypes I, II, and III was compared by sodium dodecyl sulfate polyacrylamide gel electrophoresis and peptide mapping using Staphylococcus aureus ...

journal_title：Medical microbiology and immunology

authors： Mack D,Pulz M,Heesemann J

更新日期：1991-01-01 00:00:00

abstract：:Six colonies producing antibodies were obtained by fusing mouse myeloma SP2-O cells with spleen cells from mice immunized with cytomegalovirus Davis strain. Among 88 surviving clones, 29 produced antibodies detectable by immunofluorescence on infected MRC5 cells and 2 others produced neutralizing antibodies against a ...

journal_title：Medical microbiology and immunology

authors： Chardonnet Y,Léry X,Revillard JP

更新日期：1983-01-01 00:00:00

abstract：:Phosphorylcholine (ChoP) is covalently incorporated into bacterial surface structures, contributing to host mimicry and promoting adhesion to surfaces. Our aims were to determine the frequency of ChoP display among Aggregatibacter actinomycetemcomitans strains, to clarify which surface structures bear ChoP, and whethe...

journal_title：Medical microbiology and immunology

authors： Ihalin R,Zhong D,Karched M,Chen C,Asikainen S

更新日期：2018-11-01 00:00:00

abstract：:It is known that tetraspanin proteins are involved in many physiological somatic cell mechanisms. Additionally, research has indicated they also have a role in various infectious diseases and cancers. This review focuses on the molecular interactions underlying the tetraspanin web formation in gametes. Primarily, tetr...

journal_title：Medical microbiology and immunology

authors： Jankovičová J,Neuerová Z,Sečová P,Bartóková M,Bubeníčková F,Komrsková K,Postlerová P,Antalíková J

更新日期：2020-08-01 00:00:00

abstract：:The purpose of this study was to characterize antigenic determinants on structural polypeptides of human immunodeficiency virus type 2 (HIV-2ben). Therefore, three HIV-2-specific monoclonal antibodies (mAbs) against the p24 core protein (gag) and one mAb against the gp130 envelope glycoprotein (env) were produced. In ...

journal_title：Medical microbiology and immunology

authors： Faisst AC,Otteken A,Nick S,Hunsmann G

更新日期：1993-07-01 00:00:00

abstract：:Virus adsorption and uptake of human rhinovirus 14 (HRV14) were studied with HeLa cells and baby hamster kidney (BHK) cells which were transfected with the HRV14 receptor intercellular adhesion molecule-1 (ICAM-1). Transmission electron microscopy of HeLa cells revealed that HRV14 was internalized via clathrin-coated ...

journal_title：Medical microbiology and immunology

authors： Grunert HP,Wolf KU,Langner KD,Sawitzky D,Habermehl KO,Zeichhardt H

更新日期：1997-06-01 00:00:00

abstract：:Killer cell immunoglobulin like receptors (KIRs) have a principal role in regulating the effector functions of NK cells, particularly in viral infections. The major ligands for KIRs are human leukocyte antigen (HLA) class I molecules. The aim of this study is to investigate the possible association of KIR genes, their...

journal_title：Medical microbiology and immunology

authors： Shah-Hosseini A,Jafari M,Mohammadi A,Sanaei R,Alavian SM,Doosti-Irani A,Nooradeh Keykavousi M,Tajik N

更新日期：2017-12-01 00:00:00

abstract：:Monoclonal antibody (MAb) 2c, specific for glycoprotein B of herpes simplex virus (HSV), had been shown to mediate clearance of infection from the mucous membranes of mice, thereby completely inhibiting mucocutaneous inflammation and lethality, even in mice depleted of both CD4(+) and CD8(+) cells. Additionally, gangl...

journal_title：Medical microbiology and immunology

authors： Däumer MP,Schneider B,Giesen DM,Aziz S,Kaiser R,Kupfer B,Schneweis KE,Schneider-Mergener J,Reineke U,Matz B,Eis-Hübinger AM

更新日期：2011-05-01 00:00:00

abstract：:The rapid and correct identification of pathogens is of paramount importance for the treatment of patients with invasive infections. Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) can speed up the identification of bacteria and fungi and has quickly been embraced by medical...

journal_title：Medical microbiology and immunology

authors： Hamprecht A,Christ S,Oestreicher T,Plum G,Kempf VA,Göttig S

更新日期：2014-04-01 00:00:00

abstract：:Since the dynamics of transmission of human cytomegalovirus (HCMV) have not been clarified yet, we assessed a possible change in HCMV seroprevalence in Frankfurt am Main, Germany during the past twenty years and tried to detect variables with an impact on epidemiology. Between 1/1/1988 and 10/15/2008, a total of 54443...

journal_title：Medical microbiology and immunology

authors： Lübeck PR,Doerr HW,Rabenau HF

更新日期：2010-02-01 00:00:00

abstract：:Cytomegalovirus vaccine development started in the 1970s with attenuated strains. In the 1980s, one of the strains was shown to be safe and effective in renal transplant patients. Then, attention switched to glycoprotein gB, which was shown to give moderate but transient protection against acquisition of the virus by ...

journal_title：Medical microbiology and immunology

authors： Plotkin S

更新日期：2015-06-01 00:00:00

abstract：:Roizman's definition of herpesviral latency, which applies also to cytomegaloviruses (CMVs), demands maintenance of reactivation-competent viral genomes after clearance of productive infection. It is more recent understanding that failure to complete the productive viral cycle for virus assembly and release does not i...

journal_title：Medical microbiology and immunology

authors： Renzaho A,Schmiedeke JK,Griessl M,Kühnapfel B,Seckert CK,Lemmermann NAW

更新日期：2019-08-01 00:00:00

abstract：:We have studied the incidence of enterotoxigenic and enteropathogenic Escherichia coli strains associated with infant diarrhoeal disease in Galicia (North-west Spain). During a period of 9 months we isolated heat-labile enterotoxin-positive strains in 2.1% of children with diarrhoea examined, whereas the production of...

journal_title：Medical microbiology and immunology

authors： Blanco J,González EA,Bernárdez I,Varela BR

更新日期：1983-01-01 00:00:00

abstract：:Moraxella catarrhalis is an important pathogen of respiratory and middle ear infections. We previously reported that the attachment of M. catarrhalis to pharyngeal epithelial cells is mediated by ganglioside M2 (GM2). Several sets of adhesins or receptors are involved in such attachment process. In this study, we used...

journal_title：Medical microbiology and immunology

authors： Ahmed K,Suzuki Y,Miyamoto D,Nagatake T

更新日期：2002-05-01 00:00:00

abstract：:We have examined 118 oral squamous cell carcinomas, 72 oral leukoplakias, 12 cases of cheilitis and 65 of oral lichen planus for the presence of human papillomavirus (HPV) 6/11, 16 and 18 DNA by PCR/Southern blot hybridization. HPV DNA were found in 51/118 carcinomas (43.2%), in 16/72 (22.2%) leukoplakias, 3/12 (25.0%...

journal_title：Medical microbiology and immunology

authors： Ostwald C,Rutsatz K,Schweder J,Schmidt W,Gundlach K,Barten M

更新日期：2003-08-01 00:00:00