A poroviscohyperelastic model for numerical analysis of mechanical behavior of single chondrocyte.

Abstract:

:The aim of this paper is to use a poroviscohyperelastic (PVHE) model, which is developed based on the porohyperelastic (PHE) model to explore the mechanical deformation properties of single chondrocytes. Both creep and relaxation responses are investigated by using finite element analysis models of micropipette aspiration and atomic force microscopy experiments, respectively. The newly developed PVHE model is compared thoroughly with the standard neo-Hookean solid and PHE models. It has been found that the PVHE can accurately capture both creep and stress relaxation behaviors of chondrocytes better than other two models. Hence, the PVHE is a promising model to investigate mechanical properties of single chondrocytes.

authors

Nguyen TD,Oloyede A,Gu Y

doi

10.1080/10255842.2014.996875

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

126-36

issue

2

eissn

1025-5842

issn

1476-8259

journal_volume

19

pub_type

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