Abstract:
:Generation of finite element (FE) meshes of vertebrae from computed tomography (CT) scans is labour intensive due to their geometric complexity. As such, techniques that simplify creation of meshes of vertebrae are needed to make FE analysis feasible for large studies and clinical applications. Techniques to obtain a geometric representation of bone contours from CT scans of vertebrae and construct a hexahedral mesh from the contours were developed. An automated edge detection technique was developed to identify surface contours of the vertebrae, followed by atlas based B-spline curve fitting to construct curves from the edge points. The method was automatic and robust to missing data, with a controllable degree of smoothing and interpolation. Parametric mapping was then used to generate nodes for each CT slice, which were connected between slices to obtain a hexahedral mesh. This method could be adapted for modelling a variety of orthopaedic structures.
journal_name
Comput Methods Biomech Biomed Enginauthors
Dai Y,Niebur GLdoi
10.1080/10255840902802883subject
Has Abstractpub_date
2009-10-01 00:00:00pages
599-606issue
5eissn
1025-5842issn
1476-8259pii
909810549journal_volume
12pub_type
杂志文章abstract:OBJECTIVES:The purpose of this study is to develop a validated 3D finite element model of the pelvic floor system which can offer insights into the mechanics of anterior vaginal wall prolapse and have the ability to assess biomedical device treatment methods. The finite element results should accurately mimic the clini...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2016.1186662
更新日期:2016-12-01 00:00:00
abstract::Blunt and rotational head impacts due to vehicular collisions, falls and contact sports cause relative motion between the brain and skull. This increases the normal and shear stresses in the (skull/brain) interface region consisting of cerebrospinal fluid (CSF) and subarachnoid space (SAS) trabeculae. The relative mot...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255840903064897
更新日期:2009-02-01 00:00:00
abstract::There are no blood vessels in cartilage to transport nutrients and growth factors to chondrocytes dispersed throughout the cartilage matrix. Insulin-like growth factor-I (IGF-I) is a large molecule with an important role in cartilage growth and metabolism, however, it first must reach the chondrocytes to exert its eff...
journal_title:Computer methods in biomechanics and biomedical engineering
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doi:10.1080/10255840701309163
更新日期:2007-08-01 00:00:00
abstract::Electrocardiogram (ECG) signals are difficult to interpret, and clinicians must undertake a long training process to learn to diagnose diabetes from subtle abnormalities in these signals. To facilitate these diagnoses, we have developed a technique based on the heart rate variability signal obtained from ECG signals. ...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2011.616945
更新日期:2013-01-01 00:00:00
abstract::The aim of this study was to present a new training algorithm using artificial neural networks called multi-objective least absolute shrinkage and selection operator (MOBJ-LASSO) applied to the classification of dynamic gait patterns. The movement pattern is identified by 20 characteristics from the three components o...
journal_title:Computer methods in biomechanics and biomedical engineering
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doi:10.1080/10255842.2013.803081
更新日期:2015-01-01 00:00:00
abstract::Abnormal haemodynamic parameters are associated with atheroma plaque progression and instability in coronary arteries. Flow recirculation, shear stress and pressure gradient are understood to be important pathogenic mediators in coronary disease. The effect of freedom of coronary artery movement on these parameters is...
journal_title:Computer methods in biomechanics and biomedical engineering
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doi:10.1080/10255842.2016.1215439
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abstract::At present, computer assisted surgery systems help orthopaedic surgeons both plan and perform surgical procedures. To enable these systems to function, it is crucial to have at one's disposal 3D models of anatomical structures, surgical tools and prostheses (if required). This paper analyses and compares three methods...
journal_title:Computer methods in biomechanics and biomedical engineering
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journal_title:Computer methods in biomechanics and biomedical engineering
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abstract::A two-dimensional time-dependent computational fluid dynamics model of the Circle of Willis has been developed. To simulate, not only the peripheral resistance of the cerebrovascular tree but also its auto-regulation function, a new "active" boundary condition has been defined and developed using control theory to pro...
journal_title:Computer methods in biomechanics and biomedical engineering
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更新日期:2002-02-01 00:00:00
abstract::Mechanical loading of soft tissues covering bony prominences can cause skeletal muscle damage, ultimately resulting in a severe pressure ulcer termed deep tissue injury (DTI). Deformation plays an important role in the aetiology of DTI. Therefore, it is essential to minimise internal muscle deformations in subjects at...
journal_title:Computer methods in biomechanics and biomedical engineering
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更新日期:2013-01-01 00:00:00
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journal_title:Computer methods in biomechanics and biomedical engineering
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abstract::Since the discovery of X-rays, medical imaging has played a major role in the guidance of surgical procedures. While medical imaging began with simple X-ray plates to indicate the presence of foreign objects within the human body, the advent of the computer has been a major factor in the recent development of this fie...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章,评审
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abstract::Three non-Newtonian blood viscosity models plus the Newtonian one are analysed for a patient-specific thoracic aorta anatomical model under steady-state flow conditions via wall shear stress (WSS) distribution, non-Newtonian importance factors, blood viscosity and shear rate. All blood viscosity models yield a consist...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
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更新日期:2015-08-01 00:00:00
abstract::Several opensource or commercially available software platforms are widely used to develop dynamic simulations of movement. While computational approaches are conceptually similar across platforms, technical differences in implementation may influence output. We present a new upper limb dynamic model as a tool to eval...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2014.916698
更新日期:2015-01-01 00:00:00
abstract::Local oxygen lack in arterial walls (hypoxia) plays a very important role in the initiation, progression and development of intimal hyperplasia (IH) and thrombosis. Aiming to find out whether a helical-type artery bypass graft (ABG) is hypoxia beneficial, a numerical study was carried out to compare oxygen transport b...
journal_title:Computer methods in biomechanics and biomedical engineering
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更新日期:2014-04-01 00:00:00
abstract::An efficient wavelet-based feature selection (FS) method is proposed in this paper for subject recognition using ground reaction force measurements. Our approach relies on a local fuzzy evaluation measure with respect to patterns that reveal the adequacy of data coverage for each feature. Furthermore, FS is driven by ...
journal_title:Computer methods in biomechanics and biomedical engineering
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更新日期:2012-01-01 00:00:00
abstract::The aim of this study was to investigate and present a new mapping method to describe muscle pain sensitivity based on the assessment of pressure pain threshold (PPT) over the trapezius muscle. PPT data were recorded from 36 points in 20 healthy males using a standardised grid. Points were clustered using the K-means ...
journal_title:Computer methods in biomechanics and biomedical engineering
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journal_title:Computer methods in biomechanics and biomedical engineering
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更新日期:2011-06-01 00:00:00
abstract::Transcatheter aortic valve replacement (TAVR) strongly depends on the calcification patterns, which may lead to a malapposition of the stented valve and complication onsets in terms of structure kinematics and paravalvular leakage (PVL). From one anatomical-resembling model of the aortic root, six configurations with ...
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abstract::Finite element analysis provides a means of describing cellular mechanics in tissue, which can be useful in understanding and predicting physiological and pathological changes. Many prior studies have been limited to simulations of models containing single cells, which may not accurately describe the influence of mech...
journal_title:Computer methods in biomechanics and biomedical engineering
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更新日期:2015-01-01 00:00:00
abstract::This article develops a two prion population model that simulates prion trafficking between an infected dendritic cell and a neuron. The situation when the two cells are connected by a tunnelling nanotube (TNT) is simulated. Two mechanisms of prion transport are considered: lateral diffusion in the TNT membrane and ac...
journal_title:Computer methods in biomechanics and biomedical engineering
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journal_title:Computer methods in biomechanics and biomedical engineering
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abstract::Oral cancer surgery has a negative influence on the quality of life (QOL). As a result of the complex physiology involved in oral functions, estimation of surgical effects on functionality remains difficult. We present a user-friendly biomechanical simulation of tongue surgery, including closure with suturing and scar...
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abstract::The combination of computational methods with 3D printing allows for the control of scaffolds microstructure. Lately, triply periodic minimal surfaces (TPMS) have been used to design porosity-controlled scaffolds for bone tissue engineering (TE). The goal of this work was to assess the mechanical properties of TPMS Gy...
journal_title:Computer methods in biomechanics and biomedical engineering
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abstract::Manual segmentation of articular cartilage from knee joint 3D magnetic resonance images (MRI) is a time consuming and laborious task. Thus, automatic methods are needed for faster and reproducible segmentations. In the present study, we developed a semi-automatic segmentation method based on radial intensity profiles ...
journal_title:Computer methods in biomechanics and biomedical engineering
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abstract::Musculoskeletal finite element analysis (FEA) has been essential to research in orthopaedic biomechanics. The generation of a volumetric mesh is often the most challenging step in a FEA. Hexahedral meshing tools that are based on a multi-block approach rely on the manual placement of building blocks for their mesh gen...
journal_title:Computer methods in biomechanics and biomedical engineering
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abstract::A novel, coarse-grained, single-framework 'Eulerian' model for blood flow in the microvascular circulation is presented and used to estimate the variations in flow properties that accrue from all of the following: (i) wall position variation, associated with the endothelial cells' (ECs) shape, (ii) glycocalyx layer (G...
journal_title:Computer methods in biomechanics and biomedical engineering
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abstract::Ageing influences gait patterns which in turn can affect the balance control of human locomotion. Entropy-based regularity and complexity measures have been highly effective in analysing a broad range of physiological signals. Minimum toe clearance (MTC) is an event during the swing phase of the gait cycle and is high...
journal_title:Computer methods in biomechanics and biomedical engineering
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abstract::This paper introduces a 'hypothesis about the growth pattern of the secondary ossification centre (SOC)', whereby two phases are assumed. First, the formation of cartilage canals as an event essential for the development of the SOC. Second, once the canals are merged in the central zone of the epiphysis, molecular fac...
journal_title:Computer methods in biomechanics and biomedical engineering
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journal_title:Computer methods in biomechanics and biomedical engineering
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