Abstract:
:Local oxygen lack in arterial walls (hypoxia) plays a very important role in the initiation, progression and development of intimal hyperplasia (IH) and thrombosis. Aiming to find out whether a helical-type artery bypass graft (ABG) is hypoxia beneficial, a numerical study was carried out to compare oxygen transport between a helical-type ABG and a conventional-type ABG. The dimensionless mass transfer coefficient (Sherwood number) was introduced to evaluate the oxygen mass transfer distribution and detailed oxygen wall flux was computed. The results show that the intrinsic geometry of a helical-type ABG resulted in improved hypoxia and the oxygen-depleted fluid located proximally to the occluded section as compared with that of a conventional-type ABG. However, benefits aside, distinct double low regions (low wall shear stress (WSS) and hypoxia) which might be most prone to IH and more localised and thicker boundary layer of oxygen-depleted fluid were observed at the helical-type ABG. This may explain why the helical flow plays a detrimental role at some locations in the human body. In addition, it was observed that although low WSS region was always accompanied with low oxygen supply, the oxygen transport rate did not adjust simultaneously with flow. The change in oxygen distribution usually lagged behind the flow change. A physiological WSS region may be associated with hypoxia condition. This study captured the qualitative trend of oxygen distribution in ABGs and the effect of helical geometry on reducing hypoxia, which is useful in the structural design of swirling flow vascular devices.
journal_name
Comput Methods Biomech Biomed Enginauthors
Zheng T,Wen J,Jiang W,Deng X,Fan Ydoi
10.1080/10255842.2012.702764subject
Has Abstractpub_date
2014-04-01 00:00:00pages
549-59issue
5eissn
1025-5842issn
1476-8259journal_volume
17pub_type
杂志文章abstract::Osteoporosis (OP) is common with advancing age. Several studies have shown a strong correlation between OP and otosclerosis. However, no studies have investigated OP of the malleus, incus or stapes in the human middle ear, its effect on middle ear transfer function. Here, we investigate whether these three ossicles de...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2019.1632297
更新日期:2019-10-01 00:00:00
abstract::This paper presents a procedure for characterising the mechanical properties of skin using stochastic inverse identification. It is based on the minimisation of a cost function relative to the comparison between experimental suction experiments and their corresponding finite element models. Two different models are co...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2011.633904
更新日期:2012-01-01 00:00:00
abstract::The purpose of this study was to create and validate a standardized framework for the evaluation of the ankle stiffness of two designs of 3D printed ankle foot orthoses (AFOs). The creation of four finite element (FE) models allowed patient-specific quantification of the stiffness and stress distribution over their sp...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2019.1601712
更新日期:2019-06-01 00:00:00
abstract::This article develops a two prion population model that simulates prion trafficking between an infected dendritic cell and a neuron. The situation when the two cells are connected by a tunnelling nanotube (TNT) is simulated. Two mechanisms of prion transport are considered: lateral diffusion in the TNT membrane and ac...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2013.763938
更新日期:2014-11-01 00:00:00
abstract::Mutual information (MI)-based registration, which uses MI as the similarity measure, is a representative method in medical image registration. It has an excellent robustness and accuracy, but with the disadvantages of a large amount of calculation and a long processing time. In this paper, by computing the medical ima...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2011.557372
更新日期:2012-01-01 00:00:00
abstract::In this work, we present a technique to semi-automatically quantify the epicardial fat in non-contrasted computed tomography (CT) images. The epicardial fat is very close to the pericardial fat, being separated only by the pericardium that appears in the image as a very thin line, which is hard to detect. Therefore, a...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2010.499871
更新日期:2011-10-01 00:00:00
abstract::Rupture prediction of abdominal aortic aneurysms (AAAs) remains a clinical challenge. Finite element analysis (FEA) may allow for improved identification for intervention timing, but the method needs further substantiation. In this study, experimental photoelastic method and finite element techniques were compared usi...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2011.574618
更新日期:2012-01-01 00:00:00
abstract::The International Society of Biomechanics (ISB) has recommended a standardisation for the motion reporting of almost all human joints. This study proposes an adaptation for the trapeziometacarpal joint. The definition of the segment coordinate system of both trapezium and first metacarpal is based on functional anatom...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255840802459404
更新日期:2009-06-01 00:00:00
abstract::The biomechanical effect of tensioning the lumbar fasciae (LF) on the stability of the spine during sagittal plane motion was analysed using a validated finite element model of the normal lumbosacral spine (L4-S1). To apply the tension in the LF along the direction of the fibres, a local coordinate was allocated using...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2017.1370459
更新日期:2017-10-01 00:00:00
abstract::Human brain tissue is complex and multi-component in nature. It consists of an anisotropic hyperelastic solid material composed of tissue cells and blood vessel walls. Brain tissue is permeated by two viscous pore liquids, the interstitial fluid and the blood. Both liquids are mobile within the tissue and exhibit a si...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2013.853754
更新日期:2015-01-01 00:00:00
abstract::An efficient wavelet-based feature selection (FS) method is proposed in this paper for subject recognition using ground reaction force measurements. Our approach relies on a local fuzzy evaluation measure with respect to patterns that reveal the adequacy of data coverage for each feature. Furthermore, FS is driven by ...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2011.554408
更新日期:2012-01-01 00:00:00
abstract::An appropriate method of application of the hip-joint force and stress analysis of the pelvic bone, in particular the acetabulum, is necessary to investigate the changes in load transfer due to implantation and to calculate the reference stimulus for bone remodelling simulations. The purpose of the study is to develop...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2013.843674
更新日期:2015-01-01 00:00:00
abstract::The phenotype expression in X-linked adrenoleukodystrophy is one of the most intriguing issues of the disease, because there is no general correlation between the type of ABCD1 gene mutation and the clinical phenotype. In this study, we use the cross-impact analysis to build a descriptively quantitative relationship b...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255840903279974
更新日期:2010-06-01 00:00:00
abstract::Abnormal haemodynamic parameters are associated with atheroma plaque progression and instability in coronary arteries. Flow recirculation, shear stress and pressure gradient are understood to be important pathogenic mediators in coronary disease. The effect of freedom of coronary artery movement on these parameters is...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2016.1215439
更新日期:2017-02-01 00:00:00
abstract::This study deals with recent researches undertaken by the authors in the field of hydrodynamics of human swimming. The aim of this numerical study was to investigate the flow around the entire swimmer's body. The results presented in this article focus on the combination of a 3D computational fluid dynamics code and t...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2012.683429
更新日期:2014-01-01 00:00:00
abstract::Marker-based motion capture presents the problem of gaps, which are traditionally processed using motion capture software, requiring intensive manual input. We propose and study an automated method of gap-filling that uses inverse kinematics (IK) to close the loop of an iterative process to minimize error, while nearl...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2020.1789971
更新日期:2020-11-01 00:00:00
abstract::The flow effect on the concentration of platelet active substances in the vicinity of a mural microthrombus is investigated numerically. A three-dimensional model is employed in which the mural microthrombus is modelled as a semisphere attached to a plane surface. The description of the blood flow uses the three-dimen...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/01495739808936708
更新日期:1998-01-01 00:00:00
abstract::In this study we aim at investigating the applicability of underwater 3D motion capture based on submerged video cameras in terms of 3D accuracy analysis and trajectory reconstruction. Static points with classical direct linear transform (DLT) solution, a moving wand with bundle adjustment and a moving 2D plate with Z...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2012.664637
更新日期:2013-01-01 00:00:00
abstract::In order to investigate injury mechanisms, and to provide directions for road safety system improvements, the HUMOS project has lead to the development of a 3D finite element model of the human body in driving position. The model geometry was obtained from a 50th percentile adult male. It includes the description of a...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255840310001606080
更新日期:2003-08-01 00:00:00
abstract::Fretting and corrosion at the taper-head interface in total hip arthroplasty has been reported as a potential cause of early failure of the implant system. The finite element (FE) method can be used to study the mechanics at the taper junction that are difficult to assess experimentally. Taper mismatch is one of the f...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2019.1627524
更新日期:2019-10-01 00:00:00
abstract::This paper simulates an axon with a region of reversed microtubule (MT) polarity, and investigates how the degree of polar mismatching in this region affects the formation of organelle traps in the axon. The model is based on modified Smith-Simmons equations governing molecular-motor-assisted transport in neurons. It ...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255840903505154
更新日期:2010-12-01 00:00:00
abstract::A clear and rigorous definition of muscle moment-arms in the context of musculoskeletal systems modelling is presented, using classical mechanics and screw theory. The definition provides an alternative to the tendon excursion method, which can lead to incorrect moment-arms if used inappropriately due to its dependenc...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2013.818666
更新日期:2015-01-01 00:00:00
abstract::The aim of the present study is to examine the impact absorption mechanism of the foot for different strike patterns (rearfoot, midfoot and forefoot) using a continuum mechanics approach. A three-dimensional finite element model of the foot was employed to estimate the stress distribution in the foot at the moment of ...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2018.1480760
更新日期:2018-05-01 00:00:00
abstract::Three non-Newtonian blood viscosity models plus the Newtonian one are analysed for a patient-specific thoracic aorta anatomical model under steady-state flow conditions via wall shear stress (WSS) distribution, non-Newtonian importance factors, blood viscosity and shear rate. All blood viscosity models yield a consist...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2014.887698
更新日期:2015-08-01 00:00:00
abstract::Numerical modelling of the cardiovascular system is becoming an important tool for assessing the influence of heart disease and treatment therapies. In the current study, we present an approach for modelling the interaction between the heart and the circulatory system. This was accomplished by creating animal-specific...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2011.641121
更新日期:2013-01-01 00:00:00
abstract::Woodpeckers can withstand a fierce impact during pecking without any brain injury. Although directly involved in the whole pecking, the role of the jaw apparatus played in the impact-resistant process of woodpeckers is still not fully clear. We employed finite element analysis, impact tests in vivo, and post-traumatic...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2020.1838489
更新日期:2021-01-13 00:00:00
abstract::Microstructural features including osteons and cement lines are considered to play an important role in determining the crack growth behaviour in cortical bone. This study aims to develop a computational mechanics approach to evaluate microscale fracture mechanisms in bone. In this study, finite element models based o...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2011.607444
更新日期:2013-01-01 00:00:00
abstract::Anterior percutaneous endoscopic cervical discectomy (APECD) is a common treatment for cervical spondylotic radiculopathy (CSR). In this study, the effects of various channel diameters and approach angles on cervical vertebrae on postoperative outcomes in APECD surgery were explored. A finite element model of intact c...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2020.1846186
更新日期:2020-12-01 00:00:00
abstract::This paper is motivated by recent experimental research (Tang-Schomer et al. 2012) on the formation of periodic varicosities in axons after traumatic brain injury (TBI). TBI leads to the formation of undulated distortions in the axons due to their dynamic deformation. These distortions result in the breakage of some m...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2013.820721
更新日期:2015-01-01 00:00:00
abstract::In this paper, a qualitative comparison between two types of dental implants with respect to their behaviour under immediate loading is presented. This analysis has been carried out using the finite element method. Since micromotions (and not the load) are responsible of the appearance of a fibrous interface avoiding ...
journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255840500141593
更新日期:2005-02-01 00:00:00