Abstract:
:Transcatheter aortic valve replacement (TAVR) strongly depends on the calcification patterns, which may lead to a malapposition of the stented valve and complication onsets in terms of structure kinematics and paravalvular leakage (PVL). From one anatomical-resembling model of the aortic root, six configurations with different calcific deposits were built. TAVR fluid-structure interaction simulations predicted different outcomes for the different calcifications patterns in terms of the final valve configuration in the implantation site and the PVL estimations. In particular models with deposits along the cups coaptation resulted in mild PVL, while those with deposits along the attachment line in moderate PVL.
journal_name
Comput Methods Biomech Biomed Enginauthors
Luraghi G,Matas JFR,Beretta M,Chiozzi N,Iannetti L,Migliavacca Fdoi
10.1080/10255842.2020.1817409subject
Has Abstractpub_date
2020-09-14 00:00:00pages
1-9eissn
1025-5842issn
1476-8259pub_type
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journal_title:Computer methods in biomechanics and biomedical engineering
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