Abstract:
:Burns in the airway from inhaling hot gases lead to one of the most common causes of death in the United States. In order to navigate tissues with large burn areas, the velocity, temperature, and heat flux distributions throughout the human airway system are computed for the inhalation of hot air using the finite-element method. From there, the depth of burned tissue is estimated for a range of exposure times. Additionally, the effectiveness of drug or stem cell delivery to the burned airway tissue is considered for a range of drug or cell sizes. Results showed that the highest temperature and lowest heat flux regions are observed near the pharynx and just upstream of the glottis. It was found that large particles such as stem cells (>20 μm) are effective for treatment of the upper airways, whereas small particles (<10 μm) such as drug nanoparticles are effective in the lower airways.
journal_name
Comput Methods Biomech Biomed Enginauthors
Park Sdoi
10.1080/10255842.2015.1105966subject
Has Abstractpub_date
2016-01-01 00:00:00pages
1116-26issue
10eissn
1025-5842issn
1476-8259journal_volume
19pub_type
杂志文章abstract::Numerical modelling of the cardiovascular system is becoming an important tool for assessing the influence of heart disease and treatment therapies. In the current study, we present an approach for modelling the interaction between the heart and the circulatory system. This was accomplished by creating animal-specific...
journal_title:Computer methods in biomechanics and biomedical engineering
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doi:10.1080/10255842.2011.641121
更新日期:2013-01-01 00:00:00
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journal_title:Computer methods in biomechanics and biomedical engineering
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doi:10.1080/10255842.2017.1304542
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journal_title:Computer methods in biomechanics and biomedical engineering
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doi:10.1080/10255842.2010.499869
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journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
doi:10.1080/10255842.2010.484810
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abstract::Finite element (FE) analysis is a cornerstone of orthopaedic biomechanics research. Three-dimensional medical imaging provides sufficient resolution for the subject-specific FE models to be generated from these data-sets. FE model development requires discretisation of a three-dimensional domain, which can be the most...
journal_title:Computer methods in biomechanics and biomedical engineering
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doi:10.1080/10255842.2011.570338
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journal_title:Computer methods in biomechanics and biomedical engineering
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doi:10.1080/10255842.2011.574618
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journal_title:Computer methods in biomechanics and biomedical engineering
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journal_title:Computer methods in biomechanics and biomedical engineering
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doi:10.1080/10255842.2010.545822
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journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章,评审
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journal_title:Computer methods in biomechanics and biomedical engineering
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doi:10.1080/10255842.2013.820721
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journal_title:Computer methods in biomechanics and biomedical engineering
pub_type: 杂志文章
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journal_title:Computer methods in biomechanics and biomedical engineering
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journal_title:Computer methods in biomechanics and biomedical engineering
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journal_title:Computer methods in biomechanics and biomedical engineering
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journal_title:Computer methods in biomechanics and biomedical engineering
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journal_title:Computer methods in biomechanics and biomedical engineering
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journal_title:Computer methods in biomechanics and biomedical engineering
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journal_title:Computer methods in biomechanics and biomedical engineering
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journal_title:Computer methods in biomechanics and biomedical engineering
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journal_title:Computer methods in biomechanics and biomedical engineering
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journal_title:Computer methods in biomechanics and biomedical engineering
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