A computational prediction for the effective drug and stem cell treatment of human airway burns.

abstract：:This paper proposes a micromechanics algorithm utilising the finite element method (FEM) for the analysis of heterogeneous matter. The characterisation procedure takes the material properties of the constituents, axons and extracellular matrix (ECM) as input data. The material properties of both the axons and the matr...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Abolfathi N,Naik A,Sotudeh Chafi M,Karami G,Ziejewski M

更新日期：2009-06-01 00:00:00

abstract：:The biomechanical effect of tensioning the lumbar fasciae (LF) on the stability of the spine during sagittal plane motion was analysed using a validated finite element model of the normal lumbosacral spine (L4-S1). To apply the tension in the LF along the direction of the fibres, a local coordinate was allocated using...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Choi HW,Kim YE

更新日期：2017-10-01 00:00:00

abstract：:The effect on the signal amplitude of ultrasonic waves propagating along cortical bone plates was modelled using a 2D Finite Difference code. Different healing stages, represented by modified fracture geometries were introduced to the plate model. A simple transverse and oblique fracture filled with water was introduc...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Dodd SP,Miles AW,Gheduzzi S,Humphrey VF,Cunningham JL

更新日期：2007-10-01 00:00:00

abstract：:Three-dimensional finite element models of the thoracolumbar junction (T12-L2) and isolated L1 vertebra were developed to investigate the role of material properties and loading conditions on vertebral stresses and strains to predict fracture risk. The geometry of the vertebrae was obtained from computed tomography im...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Erdem I,Truumees E,van der Meulen MC

更新日期：2013-01-01 00:00:00

abstract：:A critical point in models of the human limbs when the aim is to investigate the motor control is the muscle model. More often the mechanical output of a muscle is considered as one musculotendon force that is a design variable in optimization tasks solved predominantly by static optimization. For dynamic conditions, ...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Raikova R,Aladjov H

更新日期：2003-06-01 00:00:00

abstract：:Monitoring of skin blood flow oscillations related with mechanical activity of vessels is a very useful modality during diagnosis of peripheral hemodynamic disorders. In this study, we developed a new model and technique for real-time conversion of skin temperature into skin blood flow oscillations, and vice versa. Th...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Sagaidachnyi A,Fomin A,Usanov D,Skripal A

更新日期：2019-09-01 00:00:00

abstract：:Cell-cell and cell-matrix adhesions are fundamental to numerous physiological processes, including angiogenesis, tumourigenesis, metastatic spreading and wound healing. We use cellular potts model to computationally predict the organisation of cells within a 3D matrix. The energy potentials regulating cell-cell (JCC) ...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Singh J,Hussain F,Decuzzi P

更新日期：2015-01-01 00:00:00

abstract：:Since the discovery of X-rays, medical imaging has played a major role in the guidance of surgical procedures. While medical imaging began with simple X-ray plates to indicate the presence of foreign objects within the human body, the advent of the computer has been a major factor in the recent development of this fie...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Peters TM

更新日期：2000-01-01 00:00:00

abstract：:In some cases of aortic valve leaflet disease, the implant of a stentless biological prosthesis represents an excellent option for aortic valve replacement (AVR). In particular, if compared with the implant of mechanical valves, it provides a more physiological haemodynamic performance and a reduced thrombogeneticity,...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Auricchio F,Conti M,Ferrara A,Morganti S,Reali A

更新日期：2014-01-01 00:00:00

abstract：:The normalcy index (NI) has been implemented by several studies as a simple index for quantitatively analyzing diffident gait abnormalities, such as children with cerebral palsy and idiopathic toe-walkers. However, whether the NI can be used in anterior cruciate ligament (ACL) deficiency with different types of menisc...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Liu X,Huang H,Ren S,Rong Q,Ao Y

更新日期：2020-11-01 00:00:00

abstract：:A numerical pressure loss model previously used for adult human airways has been modified to simulate the inhalation pressure distribution in a healthy 9-month-old infant lung morphology model. Pressure distributions are calculated for air as well as helium and xenon mixtures with oxygen to investigate the effects of ...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Gouinaud L,Katz I,Martin A,Hazebroucq J,Texereau J,Caillibotte G

更新日期：2015-01-01 00:00:00

abstract：:This paper simulates an axon with a region of reversed microtubule (MT) polarity, and investigates how the degree of polar mismatching in this region affects the formation of organelle traps in the axon. The model is based on modified Smith-Simmons equations governing molecular-motor-assisted transport in neurons. It ...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Kuznetsov AV

更新日期：2010-12-01 00:00:00

abstract：:The purpose of this study is to develop a system capable of performing calculation of temporal gait parameters using two low-cost wireless accelerometers and artificial intelligence-based techniques as part of a larger research project for conducting human gait analysis. Ten healthy subjects of different ages particip...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： López-Nava IH,Muñoz-Meléndez A,Pérez Sanpablo AI,Alessi Montero A,Quiñones Urióstegui I,Núñez Carrera L

更新日期：2016-01-01 00:00:00

abstract：:This article develops a two prion population model that simulates prion trafficking between an infected dendritic cell and a neuron. The situation when the two cells are connected by a tunnelling nanotube (TNT) is simulated. Two mechanisms of prion transport are considered: lateral diffusion in the TNT membrane and ac...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Kuznetsov IA,Kuznetsov AV

更新日期：2014-11-01 00:00:00

abstract：:The purpose of this simulation study was to analyze the effect of variation in Knee-Ankle-Foot-Orthosis stiffness on the joint power and the energy cost of walking. The effect of contractile tissue was simulated using linear elastic spring and viscous dampers in knee and ankle joints. Then, joint angles, ground reacti...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Abtahi SMA,Jamshidi N,Ghaziasgar A

更新日期：2018-02-01 00:00:00

abstract：:To explore which TLIF techniques are advantageous in reducing the risk of complications and conducive to bone fusion under the vibration. The L1-L5 finite element lumbar model was modified to simulate three different TLIF techniques (a unilateral standard cage, a crescent-shaped cage, and bilateral standard cages). Th...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Wang QD,Guo LX

更新日期：2020-10-13 00:00:00

abstract：:Stress analysis determines vulnerability of dental tissues to external loads. Stress values depend on loading conditions, mechanical properties and constrains of structural components. The critical stress levels lead to tissue damage. The aim of this study is to analyse dynamic stress distribution of lower second prem...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Khani MM,Tafazzoli-Shadpour M,Aghajani F,Naderi P

更新日期：2009-10-01 00:00:00

abstract：:In order to improve the reliability of children's models, the aim of this study was to determine the subject-specific masses and 3D locations of the centres of mass (CoM) of body segments using biplanar X-rays. Previous methods, validated on upper leg segments, were applied to the whole body. Six children and six adul...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Sandoz B,Laporte S,Skalli W,Mitton D

更新日期：2010-12-01 00:00:00

abstract：:The study of the topological organisation of myocardial cells is a basic requirement for understanding the mechanical design of the normal and pathological heart. Anatomical observations show that cardiac muscle tissue has a highly specialized architecture. We have made new quantitative measurements of fibre orientati...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Ohayon J,Usson Y,Jouk PS,Cai H

更新日期：1999-01-01 00:00:00

abstract：:Fretting and corrosion at the taper-head interface in total hip arthroplasty has been reported as a potential cause of early failure of the implant system. The finite element (FE) method can be used to study the mechanics at the taper junction that are difficult to assess experimentally. Taper mismatch is one of the f...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Bitter T,Khan I,Marriott T,Lovelady E,Verdonschot N,Janssen D

更新日期：2019-10-01 00:00:00

abstract：:The primary stem stability is an essential factor for success of cementless hip stems. A correct choice of the stem geometry can improve the stem stability and, consequently, increase the life time of a hip implant. In this work, it is proposed a computational model for shape optimization of cementless hip stems. The ...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Fernandes PR,Folgado J,Ruben RB

更新日期：2004-02-01 00:00:00

abstract：:The purpose of this study was to propose an innovative approach of setting outlet boundary conditions for the computational fluid dynamics (CFD) simulation of human common carotid arteries (CCAs) bifurcation based on the concept of energy loss minimisation at flow bifurcation. Comparisons between this new approach and...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Zhang Y,Furusawa T,Sia SF,Umezu M,Qian Y

更新日期：2013-01-01 00:00:00

abstract：:This paper is motivated by recent experimental research (Tang-Schomer et al. 2012) on the formation of periodic varicosities in axons after traumatic brain injury (TBI). TBI leads to the formation of undulated distortions in the axons due to their dynamic deformation. These distortions result in the breakage of some m...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Kuznetsov IA,Kuznetsov AV

更新日期：2015-01-01 00:00:00

abstract：:Electrocardiogram (ECG) signals are difficult to interpret, and clinicians must undertake a long training process to learn to diagnose diabetes from subtle abnormalities in these signals. To facilitate these diagnoses, we have developed a technique based on the heart rate variability signal obtained from ECG signals. ...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Acharya UR,Faust O,Sree SV,Ghista DN,Dua S,Joseph P,Ahamed VI,Janarthanan N,Tamura T

更新日期：2013-01-01 00:00:00

abstract：:Computational models are increasingly being used to investigate the mechanical properties of cardiac tissue. While much insight has been gained from these studies, one important limitation associated with computational modeling arises when using in vivo images of the heart to generate the reference state of the model....

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Nikou A,Dorsey SM,McGarvey JR,Gorman JH 3rd,Burdick JA,Pilla JJ,Gorman RC,Wenk JF

更新日期：2016-12-01 00:00:00

abstract：:Peristaltic motion of a non-Newtonian Carreau fluid is analyzed in a curved channel under the long wavelength and low Reynolds number assumptions, as a simulation of digestive transport. The flow regime is shown to be governed by a dimensionless fourth-order, nonlinear, ordinary differential equation subject to no-sli...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Ali N,Javid K,Sajid M,Anwar Bég O

更新日期：2016-01-01 00:00:00

abstract：:The phenotype expression in X-linked adrenoleukodystrophy is one of the most intriguing issues of the disease, because there is no general correlation between the type of ABCD1 gene mutation and the clinical phenotype. In this study, we use the cross-impact analysis to build a descriptively quantitative relationship b...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Yan S,Wu G

更新日期：2010-06-01 00:00:00

abstract：:Convective transports in the vertebral end plate (VEP) play a significant role in the homeostasis of the spine. A few studies hypothesised that the hydraulic resistance or effective permeability of the VEP could be dependant upon fluid-flow direction. Results were influenced by species, region of interest within the e...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Swider P,Accadbled F,Laffosse JM,Sales de Gauzy J

更新日期：2012-01-01 00:00:00

abstract：:Biomechanical imaging techniques have been developed for soft tissue characterisation and detection of breast tumours. Harmonic motion imaging (HMI) uses a focused ultrasound technology to generate a harmonic radiation force in a localised region inside a soft tissue. The resulting dynamic response is used to map the ...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Zhao X,Pelegri AA

更新日期：2014-01-01 00:00:00

abstract：:The behavior of blood cells and vessel compliance significantly influence hemodynamic parameters, which are closely related to the development of aortic dissection. Here the two-phase non-Newtonian model and the fluid-structure interaction (FSI) method are coupled to simulate blood flow in a patient-specific dissected...

journal_title：Computer methods in biomechanics and biomedical engineering

authors： Qiao Y,Zeng Y,Ding Y,Fan J,Luo K,Zhu T

更新日期：2019-05-01 00:00:00