Abstract:
:The Greenland and Antarctic Ice Sheets cover ~ 10% of global land surface, but are rarely considered as active components of the global iron cycle. The ocean waters around both ice sheets harbour highly productive coastal ecosystems, many of which are iron limited. Measurements of iron concentrations in subglacial runoff from a large Greenland Ice Sheet catchment reveal the potential for globally significant export of labile iron fractions to the near-coastal euphotic zone. We estimate that the flux of bioavailable iron associated with glacial runoff is 0.40-2.54 Tg per year in Greenland and 0.06-0.17 Tg per year in Antarctica. Iron fluxes are dominated by a highly reactive and potentially bioavailable nanoparticulate suspended sediment fraction, similar to that identified in Antarctic icebergs. Estimates of labile iron fluxes in meltwater are comparable with aeolian dust fluxes to the oceans surrounding Greenland and Antarctica, and are similarly expected to increase in a warming climate with enhanced melting.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Hawkings JR,Wadham JL,Tranter M,Raiswell R,Benning LG,Statham PJ,Tedstone A,Nienow P,Lee K,Telling Jdoi
10.1038/ncomms4929subject
Has Abstractpub_date
2014-05-21 00:00:00pages
3929issn
2041-1723pii
ncomms4929journal_volume
5pub_type
杂志文章abstract::Three-dimensional (3D) assemblies based on carbon nanomaterials still lag behind their individual one-dimensional building blocks in terms of mechanical and electrical properties. Here we demonstrate a simple strategy for the fabrication of an open porous 3D self-organized double-hierarchical carbon nanotube tube stru...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-01324-7
更新日期:2017-10-31 00:00:00
abstract::Quantum technology promises revolutionizing applications in information processing, communications, sensing and modelling. However, efficient on-demand cooling of the functional quantum degrees of freedom remains challenging in many solid-state implementations, such as superconducting circuits. Here we demonstrate dir...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms15189
更新日期:2017-05-08 00:00:00
abstract::Thrombocytosis is present in more than 30% of patients with solid malignancies and correlates with worsened patient survival. Tumor cell interaction with various cellular components of the tumor microenvironment including platelets is crucial for tumor growth and metastasis. Although it is known that platelets can inf...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-00411-z
更新日期:2017-08-21 00:00:00
abstract::Antibodies conjugated to bioactive compounds allow targeted delivery of therapeutics to cell types of choice based on that antibody's specificity. Here we develop a new type of conjugate that consists of a nanobody and a peptidic ligand for a G protein-coupled receptor (GPCR), fused via their C-termini. We address act...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-15884-8
更新日期:2020-04-29 00:00:00
abstract::Understanding and reshaping cellular behaviors with synthetic gene networks requires the ability to sense and respond to changes in the intracellular environment. Intracellular proteins are involved in almost all cellular processes, and thus can provide important information about changes in cellular conditions such a...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03984-5
更新日期:2018-05-14 00:00:00
abstract::Non-invasive monitoring of gastrointestinal drug release in vivo is extremely challenging because of the limited spatial resolution and long scanning time of existing bioimaging modalities, such as X-ray radiation and magnetic resonance. Here, we report a novel microcarrier that can retain drugs and withstand the hars...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms14702
更新日期:2017-03-10 00:00:00
abstract::EGFR is required for animal development, and dysregulation of EGFR is critically implicated in malignant transformation. However, the molecular mechanism underlying the regulation of EGFR expression remains poorly explored. Here we report that the zinc-finger protein ZNF516 is a transcription repressor. ZNF516 is phys...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-00702-5
更新日期:2017-09-25 00:00:00
abstract::Bird song has historically been considered an almost exclusively male trait, an observation fundamental to the formulation of Darwin's theory of sexual selection. Like other male ornaments, song is used by male songbirds to attract females and compete with rivals. Thus, bird song has become a textbook example of the p...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4379
更新日期:2014-03-04 00:00:00
abstract::Networks of natural protein nanofibrils, such as cytoskeletal filaments, control the shape and the division of cells, yet mimicking this functionality in a synthetic setting has proved challenging. Here, we demonstrate that artificial networks of protein nanofibrils can induce controlled deformation and division of al...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-04510-3
更新日期:2018-05-29 00:00:00
abstract::The original version of this Article contained an error in Eq. 1. The arrows between the symbols "T" and "B", and "B" and "T", were written "↔" but should have been "→", and incorrectly read: IEBIC=IEBAC+ISEE+I(e↔h)+IEBICT↔B+IESEEB↔T The correct from of the Eq. 1 is as follows:IEBIC=IEBAC+ISEE+I(e↔h)+IEBICT→B+IESEEB→T...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-018-02844-6
更新日期:2018-01-24 00:00:00
abstract::Contextual influences on choice are ubiquitous in ecological settings. Current evidence suggests that subjective values are normalized with respect to the distribution of potentially available rewards. However, how this context-sensitivity is realised in the brain remains unknown. To address this, here we examine func...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12416
更新日期:2016-08-18 00:00:00
abstract::In weakly spin-orbit coupled materials, the spin-selective nature of recombination can give rise to large magnetic-field effects, e.g. on the electro-luminescence of molecular semiconductors. Although silicon has weak spin-orbit coupling, observing spin-dependent recombination through magneto-electroluminescence is ch...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-02804-6
更新日期:2018-01-26 00:00:00
abstract::Extremely metal-poor galaxies with metallicity below 10% of the solar value in the local universe are the best analogues to investigating the interstellar medium at a quasi-primitive environment in the early universe. In spite of the ongoing formation of stars in these galaxies, the presence of molecular gas (which is...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms13789
更新日期:2016-12-09 00:00:00
abstract::NHE9 (SLC9A9) is an endosomal cation/proton antiporter with orthologues in yeast and bacteria. Rare, missense substitutions in NHE9 are genetically linked with autism but have not been functionally evaluated. Here we use evolutionary conservation analysis to build a model structure of NHE9 based on the crystal structu...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3510
更新日期:2013-01-01 00:00:00
abstract::Cell fate determination requires the cooperation between extrinsic signals and intrinsic molecules including transcription factors as well as epigenetic regulators. Nevertheless, how neural fate commitment is regulated by epigenetic modifications remains largely unclear. Here we show that transient histone deacetylati...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms7830
更新日期:2015-04-23 00:00:00
abstract::Global climate change has intensified the need to assess the capacity for natural populations to adapt to abrupt shifts in the environment. Reductions in seawater pH constitute a conspicuous global change stressor that is affecting marine ecosystems globally. Here, we quantify the phenotypic and genetic modifications ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13767-1
更新日期:2019-12-20 00:00:00
abstract::Streptomycetes are notable for their complex life cycle and production of most clinically important antibiotics. A key factor that controls entry into development and the onset of antibiotic production is the 68-residue protein, BldC. BldC is a putative DNA-binding protein related to MerR regulators, but lacks coiled-...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03576-3
更新日期:2018-03-19 00:00:00
abstract::SARS-CoV-2 is the pathogen responsible for the COVID-19 pandemic. The SARS-CoV-2 papain-like cysteine protease (PLpro) has been implicated in playing important roles in virus maturation, dysregulation of host inflammation, and antiviral immune responses. The multiple functions of PLpro render it a promising drug targe...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-20718-8
更新日期:2021-01-20 00:00:00
abstract::Understanding and extracting the full functions of single-molecule characteristics are key factors in the development of future device technologies, as well as in basic research on molecular electronics. Here we report a new methodology for realizing a three-dimensional (3D) dynamic probe of single-molecule conductanc...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9465
更新日期:2015-10-06 00:00:00
abstract::Trypanosoma brucei is a protozoan parasite that evades its host's adaptive immune response by repeatedly replacing its dense variant surface glycoprotein (VSG) coat from its large genomic VSG repertoire. While the mechanisms regulating VSG gene expression and diversification have been examined extensively, the dynamic...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-00959-w
更新日期:2017-10-10 00:00:00
abstract::The evolutionary and environmental factors that shape fungal biogeography are incompletely understood. Here, we assemble a large dataset consisting of previously generated mycobiome data linked to specific geographical locations across the world. We use this dataset to describe the distribution of fungal taxa and to l...
journal_title:Nature communications
pub_type: 杂志文章,meta分析
doi:10.1038/s41467-019-13164-8
更新日期:2019-11-13 00:00:00
abstract::Theory predicts a trade-off between investments in precopulatory (ornaments and armaments) and postcopulatory (testes and ejaculates) sexual traits due to the costs associated with their growth and maintenance within the finite energy resources available. Empirical studies, however, have revealed considerable inconsis...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4184
更新日期:2014-01-01 00:00:00
abstract::Semiconductor nanowires offer the opportunity to incorporate novel structures and functionality into electronic and optoelectronic devices. A clear understanding of the nanowire growth mechanism is essential for well-controlled growth of structures with desired properties, but the understanding is currently limited by...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-12437-6
更新日期:2019-10-08 00:00:00
abstract::Identifying a bona fide population of cardiac stem cells (CSCs) is a critical step for developing cell-based therapies for heart failure patients. Previously, cardiac c-kit(+) cells were reported to be CSCs with a potential to become myocardial, endothelial and smooth muscle cells in vitro and after cardiac injury. He...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9701
更新日期:2015-10-30 00:00:00
abstract::Blood vessel expansion is driven by sprouting angiogenesis of endothelial cells, and is essential for development, wound healing and disease. Membrane-localized vascular endothelial growth factor receptor-1 (mVEGFR1) is an endothelial cell-intrinsic decoy receptor that negatively modulates blood vessel morphogenesis. ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms15699
更新日期:2017-06-07 00:00:00
abstract::Architectural proteins have an important role in shaping the genome and act as global regulators of gene expression. How these proteins jointly modulate genome plasticity is largely unknown. In archaea, one of the most abundant proteins, Alba, is considered to have a key role in organizing the genome. Here we characte...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2330
更新日期:2012-01-01 00:00:00
abstract::Mechanical signals play many roles in cell and developmental biology. Several mechanotransduction pathways have been uncovered, but the mechanisms identified so far only address the perception of stress intensity. Mechanical stresses are tensorial in nature, and thus provide dual mechanical information: stress magnitu...
journal_title:Nature communications
pub_type: 杂志文章,评审
doi:10.1038/s41467-019-10207-y
更新日期:2019-05-29 00:00:00
abstract::Erythropoietin regulates erythropoiesis in a hypoxia-inducible manner. Here we generate inherited super-anaemic mice (ISAM) as a mouse model of adult-onset anaemia caused by erythropoietin deficiency. ISAM express erythropoietin in the liver but lack erythropoietin production in the kidney. Around weaning age, when th...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2950
更新日期:2013-01-01 00:00:00
abstract::Engineering lattice thermal conductivity requires to control the heat carried by atomic vibration waves, the phonons. The key parameter for quantifying it is the phonon lifetime, limiting the travelling distance, whose determination is however at the limits of instrumental capabilities. Here, we show the achievement o...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-00584-7
更新日期:2017-09-08 00:00:00
abstract::Although chemically very simple, Fe2O3 is known to undergo a series of enigmatic structural, electronic and magnetic transformations at high pressures and high temperatures. So far, these transformations have neither been correctly described nor understood because of the lack of structural data. Here we report a syste...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10661
更新日期:2016-02-11 00:00:00