Engineering modular intracellular protein sensor-actuator devices.

abstract：:Diet is commonly assumed to affect the evolution of species, but few studies have directly tested its effect at macroevolutionary scales. Here we use Bayesian models of trait-dependent diversification and a comprehensive dietary database of all birds worldwide to assess speciation and extinction dynamics of avian diet...

journal_title：Nature communications

authors： Burin G,Kissling WD,Guimarães PR Jr,Şekercioğlu ÇH,Quental TB

更新日期：2016-04-07 00:00:00

abstract：:Electrodynamic responses from three-dimensional topological insulators are characterized by the universal magnetoelectric term constituent of the Lagrangian formalism. The quantized magnetoelectric coupling, which is generally referred to as topological magnetoelectric effect, has been predicted to induce exotic pheno...

journal_title：Nature communications

authors： Okada KN,Takahashi Y,Mogi M,Yoshimi R,Tsukazaki A,Takahashi KS,Ogawa N,Kawasaki M,Tokura Y

更新日期：2016-07-20 00:00:00

abstract：:Determination of the atomic structure of inorganic single-walled nanotubes with complex stoichiometry remains elusive due to the too many atomic coordinates to be fitted with respect to X-ray diffractograms inherently exhibiting rather broad features. Here we introduce a methodology to reduce the number of fitted vari...

journal_title：Nature communications

authors： Monet G,Amara MS,Rouzière S,Paineau E,Chai Z,Elliott JD,Poli E,Liu LM,Teobaldi G,Launois P

更新日期：2018-05-23 00:00:00

abstract：:Discharge from sliding outlet glaciers controls uncertainty in projections for future sea level. Remarkably, over 90% of glacial area is subject to gravitational driving stresses below 150 kPa (median ∼70 kPa). Longstanding explanations that appeal to the shear-thinning rheology of ice tend to overpredict driving stre...

journal_title：Nature communications

authors： Meyer CR,Downey AS,Rempel AW

更新日期：2018-08-13 00:00:00

abstract：:Adult stem cells commonly give rise to transit-amplifying progenitors, whose progeny differentiate into distinct cell types. It is unclear if stem cell niche signals coordinate fate decisions within the progenitor pool. Here we use quantitative analysis of Wnt, Hh, and Notch signalling reporters and the cell fate mark...

journal_title：Nature communications

authors： Dai W,Peterson A,Kenney T,Burrous H,Montell DJ

更新日期：2017-11-01 00:00:00

abstract：:Single-photon counters are single-pixel binary devices that click upon the absorption of a photon but obscure its spectral information, whereas resolving the color of detected photons has been in critical demand for frontier astronomical observation, spectroscopic imaging and wavelength division multiplexed quantum co...

journal_title：Nature communications

authors： Cheng R,Zou CL,Guo X,Wang S,Han X,Tang HX

更新日期：2019-09-10 00:00:00

abstract：:Stacking faults are known as defective structures in crystalline materials that typically lower the structural quality of the material. Here, we show that a particular type of defect, that is, stacking fault tetrahedra (SFTs), exhibits pronounced quantized electronic behaviour, revealing a potential synthetic route to...

journal_title：Nature communications

authors： Schouteden K,Amin-Ahmadi B,Li Z,Muzychenko D,Schryvers D,Van Haesendonck C

更新日期：2016-12-23 00:00:00

abstract：:Metal oxides with a tunnelled structure are attractive as charge storage materials for rechargeable batteries and supercapacitors, since the tunnels enable fast reversible insertion/extraction of charge carriers (for example, lithium ions). Common synthesis methods can introduce large cations such as potassium, barium...

journal_title：Nature communications

authors： Yuan Y,Zhan C,He K,Chen H,Yao W,Sharifi-Asl S,Song B,Yang Z,Nie A,Luo X,Wang H,Wood SM,Amine K,Islam MS,Lu J,Shahbazian-Yassar R

更新日期：2016-11-21 00:00:00

abstract：:The actomyosin cytoskeleton, a key stress-producing unit in epithelial cells, oscillates spontaneously in a wide variety of systems. Although much of the signal cascade regulating myosin activity has been characterized, the origin of such oscillatory behavior is still unclear. Here, we show that basal myosin II oscill...

journal_title：Nature communications

authors： Qin X,Hannezo E,Mangeat T,Liu C,Majumder P,Liu J,Choesmel-Cadamuro V,McDonald JA,Liu Y,Yi B,Wang X

更新日期：2018-03-23 00:00:00

abstract：:Itch, in particular chronic forms, has been widely recognized as an important clinical problem, but much less is known about the mechanisms of itch in comparison with other sensory modalities such as pain. Recently, considerable progress has been made in dissecting the circuit mechanisms of itch at both the spinal and...

journal_title：Nature communications

authors： Chen XJ,Sun YG

更新日期：2020-06-16 00:00:00

abstract：:Selection rules are of vital importance in determining the basic optical properties of atoms, molecules and semiconductors. They provide general insights into the symmetry of the system and the nature of relevant electronic states. A two-dimensional electron gas in a magnetic field is a model system where optical tran...

journal_title：Nature communications

authors： Ju L,Wang L,Li X,Moon S,Ozerov M,Lu Z,Taniguchi T,Watanabe K,Mueller E,Zhang F,Smirnov D,Rana F,McEuen PL

更新日期：2020-06-10 00:00:00

abstract：:Non-line-of-sight (NLOS) imaging recovers objects using diffusely reflected indirect light using transient illumination devices in combination with a computational inverse method. While capture systems capable of collecting light from the entire NLOS relay surface can be much more light efficient than single pixel poi...

journal_title：Nature communications

authors： Liu X,Bauer S,Velten A

更新日期：2020-04-02 00:00:00

abstract：:Models of visual attention postulate the existence of a saliency map whose function is to guide attention and gaze to the most conspicuous regions in a visual scene. Although cortical representations of saliency have been reported, there is mounting evidence for a subcortical saliency mechanism, which pre-dates the ev...

journal_title：Nature communications

authors： White BJ,Berg DJ,Kan JY,Marino RA,Itti L,Munoz DP

更新日期：2017-01-24 00:00:00

abstract：:Ocean ventilation is the integrated effect of various processes that exchange surface properties with the ocean interior and is essential for oxygen supply, storage of anthropogenic carbon and the heat budget of the ocean, for instance. Current observational methods utilise transient tracers, e.g. tritium, SF6, CFCs a...

journal_title：Nature communications

authors： Ebser S,Kersting A,Stöven T,Feng Z,Ringena L,Schmidt M,Tanhua T,Aeschbach W,Oberthaler MK

更新日期：2018-11-28 00:00:00

abstract：:POT1 and TPP1 are part of the shelterin complex and are essential for telomere length regulation and maintenance. Naturally occurring mutations of the telomeric POT1-TPP1 complex are implicated in familial glioma, melanoma and chronic lymphocytic leukaemia. Here we report the atomic structure of the interacting portio...

journal_title：Nature communications

authors： Rice C,Shastrula PK,Kossenkov AV,Hills R,Baird DM,Showe LC,Doukov T,Janicki S,Skordalakes E

更新日期：2017-04-10 00:00:00

abstract：:Direct reciprocity is a mechanism for cooperation among humans. Many of our daily interactions are repeated. We interact repeatedly with our family, friends, colleagues, members of the local and even global community. In the theory of repeated games, it is a tacit assumption that the various games that a person plays ...

journal_title：Nature communications

authors： Reiter JG,Hilbe C,Rand DG,Chatterjee K,Nowak MA

更新日期：2018-02-07 00:00:00

abstract：:Intestinal intraepithelial T cells contribute to the regulation of inflammatory responses in the intestine; however, the molecular basis for their development and maintenance is unknown. The aryl hydrocarbon receptor complexes with the aryl hydrocarbon receptor nuclear translocator (ARNT) and senses environmental fact...

journal_title：Nature communications

authors： Nakajima K,Maekawa Y,Kataoka K,Ishifune C,Nishida J,Arimochi H,Kitamura A,Yoshimoto T,Tomita S,Nagahiro S,Yasutomo K

更新日期：2013-01-01 00:00:00

abstract：:Semiconductor III-V photonic crystal (PC) laser is regarded as a promising ultra-compact light source with unique advantages of ultralow energy consumption and small footprint for the next generation of Si-based on-chip optical interconnects. However, the significant material dissimilarities between III-V materials an...

journal_title：Nature communications

authors： Zhou T,Tang M,Xiang G,Xiang B,Hark S,Martin M,Baron T,Pan S,Park JS,Liu Z,Chen S,Zhang Z,Liu H

更新日期：2020-02-20 00:00:00

abstract：:Materials hosting magnetic skyrmions at room temperature could enable compact and energetically-efficient storage such as racetrack memories, where information is coded by the presence/absence of skyrmions forming a moving chain through the device. The skyrmion Hall effect leading to their annihilation at the racetrac...

journal_title：Nature communications

authors： Mandru AO,Yıldırım O,Tomasello R,Heistracher P,Penedo M,Giordano A,Suess D,Finocchio G,Hug HJ

更新日期：2020-12-11 00:00:00

abstract：:Cardiac voltage-gated sodium channels (Nav1.5) play an essential role in regulating cardiac electric activity by initiating and propagating action potentials in the heart. Altered Nav1.5 function is associated with multiple cardiac diseases including long-QT3 and Brugada syndrome. Here, we show that Nav1.5 is subject ...

journal_title：Nature communications

authors： Pei Z,Xiao Y,Meng J,Hudmon A,Cummins TR

更新日期：2016-06-23 00:00:00

abstract：:The discovery of quantum spin-Hall (QSH) insulators has brought topology to the forefront of condensed matter physics. While a QSH state from spin-orbit coupling can be fully understood in terms of band theory, fascinating many-body effects are expected if it instead results from spontaneous symmetry breaking. Here, w...

journal_title：Nature communications

authors： Liu Y,Wang Z,Sato T,Hohenadler M,Wang C,Guo W,Assaad FF

更新日期：2019-06-14 00:00:00

abstract：:Following re-sequencing of the miSFIT constructs used in the paper, two of the construct variants inserted into the 3'UTR of PD-1, namely '12C' and '17A, 18G', have been found to contain additional insertions not present in the other construct variants. The data points corresponding to these constructs in Figs. 2c, f ...

journal_title：Nature communications

authors： Michaels YS,Barnkob MB,Barbosa H,Baeumler TA,Thompson MK,Andre V,Colin-York H,Fritzsche M,Gileadi U,Sheppard HM,Knapp DJHF,Milne TA,Cerundolo V,Fulga TA

更新日期：2019-06-10 00:00:00

abstract：:Motile plant structures such as Mimosa pudica leaves, Impatiens glandulifera seedpods, and Dionaea muscipula leaves exhibit fast nastic movements in a few seconds or less. This motion is stimuli-independent mechanical movement following theorema egregium rules. Artificial analogs of tropistic motion in plants are exem...

journal_title：Nature communications

authors： Tian Z,Xu B,Wan G,Han X,Di Z,Chen Z,Mei Y

更新日期：2021-01-21 00:00:00

abstract：:We introduce a microfluidic platform that enables off-chip single-cell RNA-seq after multi-generational lineage tracking under controlled culture conditions. We use this platform to generate whole-transcriptome profiles of primary, activated murine CD8+ T-cell and lymphocytic leukemia cell line lineages. Here we repor...

journal_title：Nature communications

authors： Kimmerling RJ,Lee Szeto G,Li JW,Genshaft AS,Kazer SW,Payer KR,de Riba Borrajo J,Blainey PC,Irvine DJ,Shalek AK,Manalis SR

更新日期：2016-01-06 00:00:00

abstract：:Graphene nanopores are potential successors to biological and silicon-based nanopores. For sensing applications, it is however crucial to understand and block the strong nonspecific hydrophobic interactions between DNA and graphene. Here we demonstrate a novel scheme to prevent DNA-graphene interactions, based on a ta...

journal_title：Nature communications

authors： Schneider GF,Xu Q,Hage S,Luik S,Spoor JN,Malladi S,Zandbergen H,Dekker C

更新日期：2013-01-01 00:00:00

abstract：:Zea mays is an important genetic model for elucidating transcriptional networks. Uncertainties about the complete structure of mRNA transcripts limit the progress of research in this system. Here, using single-molecule sequencing technology, we produce 111,151 transcripts from 6 tissues capturing ∼70% of the genes ann...

journal_title：Nature communications

authors： Wang B,Tseng E,Regulski M,Clark TA,Hon T,Jiao Y,Lu Z,Olson A,Stein JC,Ware D

更新日期：2016-06-24 00:00:00

abstract：:Enterobacteria, especially Escherichia coli, are abundant in patients with inflammatory bowel disease or colorectal cancer (CRC). However, it is unclear whether cancer is promoted by inflammation-induced expansion of E. coli and/or changes in expression of specific microbial genes. Here we use longitudinal (2, 12 and ...

journal_title：Nature communications

authors： Arthur JC,Gharaibeh RZ,Mühlbauer M,Perez-Chanona E,Uronis JM,McCafferty J,Fodor AA,Jobin C

更新日期：2014-09-03 00:00:00

abstract：:Innovations in soft material synthesis and fabrication technologies have led to the development of integrated soft electronic devices. Such soft devices offer opportunities to interact with biological cells, mimicking their soft environment. However, existing fabrication technologies cannot create the submicron-scale,...

journal_title：Nature communications

authors： Kim MG,Brown DK,Brand O

更新日期：2020-02-21 00:00:00

abstract：:The Cas9 endonuclease can be targeted to genomic sequences by programming the sequence of an associated single guide RNA (sgRNA). For unknown reasons, the activity of these Cas9-sgRNA combinations varies widely at different genomic loci and in different cell types. Thus, disrupting genes in polyploid cell lines or whe...

journal_title：Nature communications

authors： Richardson CD,Ray GJ,Bray NL,Corn JE

更新日期：2016-08-17 00:00:00

abstract：:Changes in cellular metabolism are associated with the activation of diverse immune subsets. These changes are fuelled by nutrients including glucose, amino acids and fatty acids, and are closely linked to immune cell fate and function. An emerging concept is that nutrients are not equally available to all immune cell...

journal_title：Nature communications

authors： Kedia-Mehta N,Finlay DK

更新日期：2019-05-09 00:00:00