Superior colliculus neurons encode a visual saliency map during free viewing of natural dynamic video.

abstract：:Engineering lattice thermal conductivity requires to control the heat carried by atomic vibration waves, the phonons. The key parameter for quantifying it is the phonon lifetime, limiting the travelling distance, whose determination is however at the limits of instrumental capabilities. Here, we show the achievement o...

journal_title：Nature communications

authors： Lory PF,Pailhès S,Giordano VM,Euchner H,Nguyen HD,Ramlau R,Borrmann H,Schmidt M,Baitinger M,Ikeda M,Tomeš P,Mihalkovič M,Allio C,Johnson MR,Schober H,Sidis Y,Bourdarot F,Regnault LP,Ollivier J,Paschen S,Grin Y,d

更新日期：2017-09-08 00:00:00

abstract：:Electric gating can strongly modulate a wide variety of physical properties in semiconductors and insulators, such as significant changes of conductivity in silicon, appearance of superconductivity in SrTiO3, the paramagnet-ferromagnet transition in (In,Mn)As, and so on. The key to such modulation is charge accumulati...

journal_title：Nature communications

authors： Dushenko S,Hokazono M,Nakamura K,Ando Y,Shinjo T,Shiraishi M

更新日期：2018-08-07 00:00:00

abstract：:Survival in complex environments necessitates a flexible navigation system that incorporates memory of recent behavior and associations. Yet, how the hippocampal spatial circuit represents latent information independent of sensory inputs and future goals has not been determined. To address this, we image the activity ...

journal_title：Nature communications

authors： Keinath AT,Nieto-Posadas A,Robinson JC,Brandon MP

更新日期：2020-06-15 00:00:00

abstract：:Hereditary retinal degenerations (HRDs) are Mendelian diseases characterized by progressive blindness and caused by ultra-rare mutations. In a genomic screen of 331 unrelated Japanese patients, we identify a disruptive Alu insertion and a nonsense variant (p.Arg1933*) in the ciliary gene RP1, neither of which are rare...

journal_title：Nature communications

authors： Nikopoulos K,Cisarova K,Quinodoz M,Koskiniemi-Kuendig H,Miyake N,Farinelli P,Rehman AU,Khan MI,Prunotto A,Akiyama M,Kamatani Y,Terao C,Miya F,Ikeda Y,Ueno S,Fuse N,Murakami A,Wada Y,Terasaki H,Sonoda KH,Ishibashi

更新日期：2019-06-28 00:00:00

abstract：:The high incidence of aneuploidy in the embryo is considered the principal cause for low human fecundity. However, the prevalence of aneuploidy dramatically declines as pregnancy progresses, with the steepest drop occurring as the embryo completes implantation. Despite the fact that the plasticity of the embryo in dea...

journal_title：Nature communications

authors： Singla S,Iwamoto-Stohl LK,Zhu M,Zernicka-Goetz M

更新日期：2020-06-11 00:00:00

abstract：:Most DNA in the genomes of higher organisms does not encode proteins, yet much is transcribed by RNA polymerase II (RNAPII) into long non-coding RNAs (lncRNAs). The biological significance of most lncRNAs is largely unclear. Here, we identify a lncRNA (SVALKA) in a cold-sensitive region of the Arabidopsis genome. Muta...

journal_title：Nature communications

authors： Kindgren P,Ard R,Ivanov M,Marquardt S

更新日期：2018-11-01 00:00:00

abstract：:Despite over a century of interest, the function of zebra stripes has never been examined systematically. Here we match variation in striping of equid species and subspecies to geographic range overlap of environmental variables in multifactor models controlling for phylogeny to simultaneously test the five major expl...

journal_title：Nature communications

authors： Caro T,Izzo A,Reiner RC Jr,Walker H,Stankowich T

更新日期：2014-04-01 00:00:00

abstract：:Cytokines are involved in early host defense against pathogen infections. In particular, tumor necrosis factor (TNF) and interferon-gamma (IFN-γ) have critical functions in non-cytopathic elimination of hepatitis B virus (HBV) in hepatocytes. However, the molecular mechanisms and mediator molecules are largely unknown...

journal_title：Nature communications

authors： Kim DH,Park ES,Lee AR,Park S,Park YK,Ahn SH,Kang HS,Won JH,Ha YN,Jae B,Kim DS,Chung WC,Song MJ,Kim KH,Park SH,Kim SH,Kim KH

更新日期：2018-08-16 00:00:00

abstract：:Clonal expansions occur in the persistent HIV reservoir as shown by the duplication of proviral integration sites. However, the source of the proliferation of HIV-infected cells remains unclear. Here, we analyze the TCR repertoire of single HIV-infected cells harboring translation-competent proviruses in longitudinal ...

journal_title：Nature communications

authors： Gantner P,Pagliuzza A,Pardons M,Ramgopal M,Routy JP,Fromentin R,Chomont N

更新日期：2020-08-14 00:00:00

abstract：:The responses of atmospheric variability to Tibetan Plateau (TP) snow cover (TPSC) at seasonal, interannual and decadal time scales have been extensively investigated. However, the atmospheric response to faster subseasonal variability of TPSC has been largely ignored. Here, we show that the subseasonal variability of...

journal_title：Nature communications

authors： Li W,Guo W,Qiu B,Xue Y,Hsu PC,Wei J

更新日期：2018-10-12 00:00:00

abstract：:Understanding the behaviour of thermally excited many-particle systems, composed of a single particle type having a well-defined shape and size, is important in condensed matter, notably protein crystallization. Here we observe and explain the origin of local chiral symmetry breaking in a surprisingly simple system of...

journal_title：Nature communications

authors： Zhao K,Bruinsma R,Mason TG

更新日期：2012-05-01 00:00:00

abstract：:The unique properties of ferroelectric materials enable a plethora of applications, which are hindered by the phenomenon known as ferroelectric fatigue that leads to the degradation of ferroelectric properties with polarization cycling. Multiple microscopic models explaining fatigue have been suggested; however, the c...

journal_title：Nature communications

authors： Ievlev AV,Kc S,Vasudevan RK,Kim Y,Lu X,Alexe M,Cooper VR,Kalinin SV,Ovchinnikova OS

更新日期：2019-07-11 00:00:00

abstract：:Current knowledge on chromosomal mosaicism in human cell cultures is mostly based on cytogenetic banding methods. The recent development of high-resolution full-genome analysis methods applicable to single cells is providing new insights into genetic and cellular diversity. Here we study the genetic content of 92 indi...

journal_title：Nature communications

authors： Jacobs K,Mertzanidou A,Geens M,Nguyen HT,Staessen C,Spits C

更新日期：2014-06-27 00:00:00

abstract：:Normalization is a common cortical computation widely observed in sensory perception, but its importance in perception of reward value and decision making remains largely unknown. We examined (1) whether normalized value signals occur in the orbitofrontal cortex (OFC) and (2) whether changes in behavioral task context...

journal_title：Nature communications

authors： Yamada H,Louie K,Tymula A,Glimcher PW

更新日期：2018-01-11 00:00:00

abstract：:The ability to identify cause-effect relations is an essential component of the scientific method. The identification of causal relations is generally accomplished through statistical trials where alternative hypotheses are tested against each other. Traditionally, such trials have been based on classical statistics. ...

journal_title：Nature communications

authors： Chiribella G,Ebler D

更新日期：2019-04-01 00:00:00

abstract：:In vitro fabrication of functional vascularized three-dimensional tissues has been a long-standing objective in the field of tissue engineering. Here we report a technique to engineer cardiac tissues with perfusable blood vessels in vitro. Using resected tissue with a connectable artery and vein as a vascular bed, we ...

journal_title：Nature communications

authors： Sekine H,Shimizu T,Sakaguchi K,Dobashi I,Wada M,Yamato M,Kobayashi E,Umezu M,Okano T

更新日期：2013-01-01 00:00:00

abstract：:Understanding how cellular functions emerge from the underlying molecular mechanisms is a key challenge in biology. This will require computational models, whose predictive power is expected to increase with coverage and precision of formulation. Genome-scale models revolutionised the metabolic field and made the firs...

journal_title：Nature communications

authors： Münzner U,Klipp E,Krantz M

更新日期：2019-03-21 00:00:00

abstract：:Hedgehog (Hh) signalling regulates embryonic development and adult tissue homoeostasis. Mutations of its pathway components including Suppressor of Fused (Sufu) and Gli/Ci predispose to cancers and congenital anomalies. The Sufu-Gli protein complex occupies a central position in the vertebrate Hh signalling pathway, e...

journal_title：Nature communications

authors： Zhang Y,Fu L,Qi X,Zhang Z,Xia Y,Jia J,Jiang J,Zhao Y,Wu G

更新日期：2013-01-01 00:00:00

abstract：:The survival of viruses partly relies on their ability to self-assemble inside host cells. Although coarse-grained simulations have identified different pathways leading to assembled virions from their components, experimental evidence is severely lacking. Here, we use time-resolved small-angle X-ray scattering to unc...

journal_title：Nature communications

authors： Chevreuil M,Law-Hine D,Chen J,Bressanelli S,Combet S,Constantin D,Degrouard J,Möller J,Zeghal M,Tresset G

更新日期：2018-08-06 00:00:00

abstract：:The androgen receptor (AR) plays a central role in establishing an oncogenic cascade that drives prostate cancer progression. Some prostate cancers escape androgen dependence and are often associated with an aggressive phenotype. The oestrogen receptor alpha (ERα) is expressed in prostate cancers, independent of AR st...

journal_title：Nature communications

authors： Chakravarty D,Sboner A,Nair SS,Giannopoulou E,Li R,Hennig S,Mosquera JM,Pauwels J,Park K,Kossai M,MacDonald TY,Fontugne J,Erho N,Vergara IA,Ghadessi M,Davicioni E,Jenkins RB,Palanisamy N,Chen Z,Nakagawa S,Hirose T

更新日期：2014-11-21 00:00:00

abstract：:Microbial communities mediating anaerobic ammonium oxidation (anammox) represent one of the most energy-efficient environmental biotechnologies for nitrogen removal from wastewater. However, little is known about the functional role heterotrophic bacteria play in anammox granules. Here, we use genome-centric metagenom...

journal_title：Nature communications

authors： Lawson CE,Wu S,Bhattacharjee AS,Hamilton JJ,McMahon KD,Goel R,Noguera DR

更新日期：2017-05-31 00:00:00

abstract：:Textiles that are capable of harvesting biomechanical energy via triboelectric effects are of interest for self-powered wearable electronics. Fabrication of conformable and durable textiles with high triboelectric outputs remains challenging. Here we propose a washable skin-touch-actuated textile-based triboelectric n...

journal_title：Nature communications

authors： Xiong J,Cui P,Chen X,Wang J,Parida K,Lin MF,Lee PS

更新日期：2018-10-15 00:00:00

abstract：:Viruses provide top-down control on microbial communities, yet their direct study in natural environments was hindered by culture limitations. The advance of bioinformatics enables cultivation-independent study of viruses. Many studies assemble new viral genomes and study viral diversity using marker genes from free v...

journal_title：Nature communications

authors： Sieradzki ET,Ignacio-Espinoza JC,Needham DM,Fichot EB,Fuhrman JA

更新日期：2019-03-12 00:00:00

abstract：:Tessellation of self-assembling molecular building blocks is a promising strategy to design metal-organic materials exhibiting geometrical frustration and ensuing frustrated physical properties. Appearing in two-dimensional quasiperiodic phases, tilings consisting of five-vertex nodes are regarded as approximants for ...

journal_title：Nature communications

authors： Voigt L,Kubus M,Pedersen KS

更新日期：2020-09-17 00:00:00

abstract：:Parkinson's disease-associated kinase LRRK2 has been linked to IFN type II (IFN-γ) response in infections and to dopaminergic neuronal loss. However, whether and how LRRK2 synergizes with IFN-γ remains unclear. In this study, we employed dopaminergic neurons and microglia differentiated from patient-derived induced pl...

journal_title：Nature communications

authors： Panagiotakopoulou V,Ivanyuk D,De Cicco S,Haq W,Arsić A,Yu C,Messelodi D,Oldrati M,Schöndorf DC,Perez MJ,Cassatella RP,Jakobi M,Schneiderhan-Marra N,Gasser T,Nikić-Spiegel I,Deleidi M

更新日期：2020-10-14 00:00:00

abstract：:In order to control and eradicate epidemic cholera, we need to understand how epidemics begin, how they spread, and how they decline and eventually end. This requires extensive sampling of epidemic disease over time, alongside the background of endemic disease that may exist concurrently with the epidemic. The unique ...

journal_title：Nature communications

authors： Dorman MJ,Domman D,Poklepovich T,Tolley C,Zolezzi G,Kane L,Viñas MR,Panagópulo M,Moroni M,Binsztein N,Caffer MI,Clare S,Dougan G,Salmond GPC,Parkhill J,Campos J,Thomson NR

更新日期：2020-10-01 00:00:00

abstract：:Around 40% of preterm births are attributed to ascending intrauterine infection, and Ureaplasma parvum (UP) is commonly isolated in these cases. Here we present a mouse model of ascending UP infection that resembles human disease, using vaginal inoculation combined with mild cervical injury induced by a common spermic...

journal_title：Nature communications

authors： Pavlidis I,Spiller OB,Sammut Demarco G,MacPherson H,Howie SEM,Norman JE,Stock SJ

更新日期：2020-01-10 00:00:00

abstract：:Thin films of several microns in thickness are ubiquitously used in packaging, electronics, and acoustic sensors. Here we demonstrate that natural wood can be directly converted into an ultrathin film with a record-small thickness of less than 10 μm through partial delignification followed by densification. Benefiting...

journal_title：Nature communications

authors： Gan W,Chen C,Kim HT,Lin Z,Dai J,Dong Z,Zhou Z,Ping W,He S,Xiao S,Yu M,Hu L

更新日期：2019-11-08 00:00:00

abstract：:Bacterial infections and antibiotic resistance, particularly by Gram-negative pathogens, have become a global healthcare crisis. We report the design of a class of cationic antimicrobial polymers that cluster local facial amphiphilicity from repeating units to enhance interactions with bacterial membranes without requ...

journal_title：Nature communications

authors： Rahman MA,Bam M,Luat E,Jui MS,Ganewatta MS,Shokfai T,Nagarkatti M,Decho AW,Tang C

更新日期：2018-12-07 00:00:00

abstract：:Plant metacaspases mediate programmed cell death in development, biotic and abiotic stresses, damage-induced immune response, and resistance to pathogen attack. Most metacaspases require Ca2+ for their activation and substrate processing. However, the Ca2+-dependent activation mechanism remains elusive. Here we report...

journal_title：Nature communications

authors： Zhu P,Yu XH,Wang C,Zhang Q,Liu W,McSweeney S,Shanklin J,Lam E,Liu Q

更新日期：2020-05-07 00:00:00