The function of zebra stripes.

abstract：:Bipolar spindle assembly is a critical control point for initiation of mitosis through nucleation and organization of spindle microtubules and is regulated by kinesin-like proteins. In fission yeast, the kinesin-14 Pkl1 binds the γ-tubulin ring complex (γ-TuRC) microtubule-organizing centre at spindle poles and can al...

journal_title：Nature communications

authors： Olmsted ZT,Colliver AG,Riehlman TD,Paluh JL

更新日期：2014-10-28 00:00:00

abstract：:Properties of human brain tissue change across the lifespan. Here we model these changes in the living human brain by combining quantitative magnetic resonance imaging (MRI) measurements of R1 (1/T1) with diffusion MRI and tractography (N=102, ages 7-85). The amount of R1 change during development differs between whit...

journal_title：Nature communications

authors： Yeatman JD,Wandell BA,Mezer AA

更新日期：2014-09-17 00:00:00

abstract：:Supported atomic clusters with uniform metal sites and definite low-nuclearity are intermediate states between single-atom catalysts (SACs) and nanoparticles in size. Benefiting from the presence of metal-metal bonds, supported atomic clusters can trigger synergistic effects among every metal atom, which contributes t...

journal_title：Nature communications

authors： Rong H,Ji S,Zhang J,Wang D,Li Y

更新日期：2020-11-18 00:00:00

abstract：:Since the 1970s, it has been known that black-hole (and other) horizons are truly thermodynamic. More generally, surfaces which are not horizons have also been conjectured to behave thermodynamically. Initially, for surfaces microscopically expanded from a horizon to so-called stretched horizons, and more recently, fo...

journal_title：Nature communications

authors： Wang ZW,Braunstein SL

更新日期：2018-07-30 00:00:00

abstract：:Maintaining DNA integrity is vital for all cells and organisms. Defective DNA repair may contribute to neurological disorders, including Alzheimer's disease (AD). We found reduced levels of BRCA1, but not of other DNA repair factors, in the brains of AD patients and human amyloid precursor protein (hAPP) transgenic mi...

journal_title：Nature communications

authors： Suberbielle E,Djukic B,Evans M,Kim DH,Taneja P,Wang X,Finucane M,Knox J,Ho K,Devidze N,Masliah E,Mucke L

更新日期：2015-11-30 00:00:00

abstract：:Generation of coherent light with desirable amplitude and phase profiles throughout the optical spectrum is a key issue in optical technologies. Nonlinear wavefront shaping offers an exceptional way to achieve this goal by converting an incident light beam into the beam (or beams) of different frequency with spatially...

journal_title：Nature communications

authors： Liu S,Switkowski K,Xu C,Tian J,Wang B,Lu P,Krolikowski W,Sheng Y

更新日期：2019-07-19 00:00:00

abstract：:Glucagon is released from pancreatic α-cells to activate pathways that raise blood glucose. Its secretion is regulated by α-cell-intrinsic glucose sensing and paracrine control through insulin and somatostatin. To understand the inadequately high glucagon levels that contribute to hyperglycemia in type-2 diabetes (T2D...

journal_title：Nature communications

authors： Omar-Hmeadi M,Lund PE,Gandasi NR,Tengholm A,Barg S

更新日期：2020-04-20 00:00:00

abstract：:It has been postulated that synaptic potentiation during waking is offset by a homoeostatic reduction in net synaptic strength during sleep. However, molecular mechanisms to support such a process are lacking. Here we demonstrate that deficiencies in the RNA-editing gene Adar increase sleep due to synaptic dysfunction...

journal_title：Nature communications

authors： Robinson JE,Paluch J,Dickman DK,Joiner WJ

更新日期：2016-01-27 00:00:00

abstract：:Nitrogen acquisition is a major challenge for herbivorous animals, and the repeated origins of herbivory across the ants have raised expectations that nutritional symbionts have shaped their diversification. Direct evidence for N provisioning by internally housed symbionts is rare in animals; among the ants, it has be...

journal_title：Nature communications

authors： Hu Y,Sanders JG,Łukasik P,D'Amelio CL,Millar JS,Vann DR,Lan Y,Newton JA,Schotanus M,Kronauer DJC,Pierce NE,Moreau CS,Wertz JT,Engel P,Russell JA

更新日期：2018-03-06 00:00:00

abstract：:The midge, Belgica antarctica, is the only insect endemic to Antarctica, and thus it offers a powerful model for probing responses to extreme temperatures, freeze tolerance, dehydration, osmotic stress, ultraviolet radiation and other forms of environmental stress. Here we present the first genome assembly of an extre...

journal_title：Nature communications

authors： Kelley JL,Peyton JT,Fiston-Lavier AS,Teets NM,Yee MC,Johnston JS,Bustamante CD,Lee RE,Denlinger DL

更新日期：2014-08-12 00:00:00

abstract：:Rabi oscillations describe the process whereby electromagnetic radiation interacts coherently with spin states in a non-equilibrium interaction. To date, Rabi oscillations have not been studied in one of the most common spin ensembles in nature: spins in ferromagnets. Here, using a combination of femtosecond laser pul...

journal_title：Nature communications

authors： Capua A,Rettner C,Yang SH,Phung T,Parkin SSP

更新日期：2017-06-28 00:00:00

abstract：:The original version of this Article contained an error in the third sentence of the penultimate paragraph of the 'Definition of the harmonic phase' section of the Results, which incorrectly read 'In the Coulomb phase the tensor S αβ (q) has one zero and two degenerate eigenvalues and it may be represented by an infin...

journal_title：Nature communications

authors： Bramwell ST

更新日期：2018-04-16 00:00:00

abstract：:Striatum processes a wide range of functions including goal-directed behavior and habit formation, respectively encoded by the dorsomedial striatum (DMS) and dorsolateral striatum (DLS). GABAergic feedforward inhibition is known to control the integration of cortical information by striatal projection neurons (SPNs). ...

journal_title：Nature communications

authors： Fino E,Vandecasteele M,Perez S,Saudou F,Venance L

更新日期：2018-08-21 00:00:00

abstract：:Conventional rigid electronic systems use a number of metallization layers to route all necessary connections to and from isolated surface mount devices using well-established printed circuit board technology. In contrast, present solutions to prepare stretchable electronic systems are typically confined to a single s...

journal_title：Nature communications

authors： Biswas S,Schoeberl A,Hao Y,Reiprich J,Stauden T,Pezoldt J,Jacobs HO

更新日期：2019-10-28 00:00:00

abstract：:Preparation and characterization of polariton Bose-Einstein condensates in micro-cavities of high quality are at the frontier of contemporary solid state physics. Here, we report on three-dimensional polariton condensation and confinement in pseudo-spherical ZnO microcrystals. The boundary of micro-spherical ZnO resem...

journal_title：Nature communications

authors： Volkov VV,Oliver DJ,Perry CC

更新日期：2020-09-30 00:00:00

abstract：:Cyclic nucleotide-binding (CNB) domains allosterically regulate the activity of proteins with diverse functions, but the mechanisms that enable the cyclic nucleotide-binding signal to regulate distant domains are not well understood. Here we use optical tweezers and molecular dynamics to dissect changes in folding ene...

journal_title：Nature communications

authors： Hao Y,England JP,Bellucci L,Paci E,Hodges HC,Taylor SS,Maillard RA

更新日期：2019-09-04 00:00:00

abstract：:Plant metacaspases mediate programmed cell death in development, biotic and abiotic stresses, damage-induced immune response, and resistance to pathogen attack. Most metacaspases require Ca2+ for their activation and substrate processing. However, the Ca2+-dependent activation mechanism remains elusive. Here we report...

journal_title：Nature communications

authors： Zhu P,Yu XH,Wang C,Zhang Q,Liu W,McSweeney S,Shanklin J,Lam E,Liu Q

更新日期：2020-05-07 00:00:00

abstract：:Radiofrequency switches are critical components in wireless communication systems and consumer electronics. Emerging devices include switches based on microelectromechanical systems and phase-change materials. However, these devices suffer from disadvantages such as large physical dimensions and high actuation voltage...

journal_title：Nature communications

authors： Pi S,Ghadiri-Sadrabadi M,Bardin JC,Xia Q

更新日期：2015-06-25 00:00:00

abstract：:Although environmental selection and spatial separation have been shown to shape the distribution and abundance of marine microorganisms, the effects of advection (physical transport) have not been directly tested. Here we examine 25 samples covering all major water masses of the Southern Ocean to determine the effect...

journal_title：Nature communications

authors： Wilkins D,van Sebille E,Rintoul SR,Lauro FM,Cavicchioli R

更新日期：2013-01-01 00:00:00

abstract：:By electrochemically coupling microbial and abiotic catalysts, bioelectrochemical systems such as microbial electrolysis cells and microbial electrosynthesis systems synthesize energy-rich chemicals from energy-poor precursors with unmatched efficiency. However, to circumvent chemical incompatibilities between the mic...

journal_title：Nature communications

authors： Cornejo JA,Sheng H,Edri E,M Ajo-Franklin C,Frei H

更新日期：2018-06-11 00:00:00

abstract：:Transcription in all living organisms is accomplished by multi-subunit RNA polymerases (msRNAPs). msRNAPs are highly conserved in evolution and invariably share a ∼400 kDa five-subunit catalytic core. Here we characterize a hypothetical ∼100 kDa single-chain protein, YonO, encoded by the SPβ prophage of Bacillus subti...

journal_title：Nature communications

authors： Forrest D,James K,Yuzenkova Y,Zenkin N

更新日期：2017-06-06 00:00:00

abstract：:It is well known that both recipient cells and donor nuclei demonstrate a mitotic advantage as observed in the traditional reprogramming with somatic cell nuclear transfer (SCNT). However, it is not known whether a specific mitotic factor plays a critical role in reprogramming. Here we identify an isoform of human bro...

journal_title：Nature communications

authors： Shao Z,Zhang R,Khodadadi-Jamayran A,Chen B,Crowley MR,Festok MA,Crossman DK,Townes TM,Hu K

更新日期：2016-03-07 00:00:00

abstract：:Nuclear factor-κB (NFκB) and peroxisome proliferator activated receptor-γ (PPARγ) are both transcription factors that perform distinct but overlapping roles in cellular regulation. Here we report that PPARγ acts as an E3 ubiquitin ligase, physically interacting with p65 to induce its ubiquitination and degradation. Th...

journal_title：Nature communications

authors： Hou Y,Moreau F,Chadee K

更新日期：2012-01-01 00:00:00

abstract：:Clusters of enhancers, referred as to super-enhancers (SEs), control the expression of cell identity genes. The organisation of these clusters, and how they are remodelled upon developmental transitions remain poorly understood. Here, we report the existence of two types of enhancer units within SEs typified by distin...

journal_title：Nature communications

authors： Bell E,Curry EW,Megchelenbrink W,Jouneau L,Brochard V,Tomaz RA,Mau KHT,Atlasi Y,de Souza RA,Marks H,Stunnenberg HG,Jouneau A,Azuara V

更新日期：2020-02-28 00:00:00

abstract：:Cancer persister cells tolerate anticancer drugs and serve as the founders of acquired resistance and cancer relapse. Here we show that a subpopulation of BRAFV600 mutant melanoma cells that tolerates exposure to BRAF and MEK inhibitors undergoes a reversible remodelling of mRNA translation that evolves in parallel wi...

journal_title：Nature communications

authors： Shen S,Faouzi S,Bastide A,Martineau S,Malka-Mahieu H,Fu Y,Sun X,Mateus C,Routier E,Roy S,Desaubry L,André F,Eggermont A,David A,Scoazec JY,Vagner S,Robert C

更新日期：2019-12-16 00:00:00

abstract：:The Sun's activity cycle governs the radiation, particle and magnetic flux in the heliosphere creating hazardous space weather. Decadal-scale variations define space climate and force the Earth's atmosphere. However, predicting the solar cycle is challenging. Current understanding indicates a short window for predicti...

journal_title：Nature communications

authors： Bhowmik P,Nandy D

更新日期：2018-12-06 00:00:00

abstract：:Colloidal interactions in nematic liquid crystals can be described as interactions between elastic multipoles that depend on particle shape, topology, chirality, boundary conditions and induced topological defects. Here, we describe a nematic colloidal system consisting of mesostructures of gold capable of inducing el...

journal_title：Nature communications

authors： Yuan Y,Tasinkevych M,Smalyukh II

更新日期：2020-01-10 00:00:00

abstract：:Insulin-like growth factors (IGFs) induce proliferation of various cell types and play important roles in somatic growth and cancer development. Phosphorylation of insulin receptor substrate (IRS)-1/2 by IGF-I receptor tyrosine kinase is essential for IGF action. Here we identify Nedd4 as an IRS-2 ubiquitin ligase. Ne...

journal_title：Nature communications

authors： Fukushima T,Yoshihara H,Furuta H,Kamei H,Hakuno F,Luan J,Duan C,Saeki Y,Tanaka K,Iemura S,Natsume T,Chida K,Nakatsu Y,Kamata H,Asano T,Takahashi S

更新日期：2015-04-16 00:00:00

abstract：:The sensitivity of quantum magnetometer is challenged by control errors and, especially in the solid state, by their short coherence times. Refocusing techniques can overcome these limitations and improve the sensitivity to periodic fields, but they come at the cost of reduced bandwidth and cannot be applied to sense ...

journal_title：Nature communications

authors： Aiello CD,Hirose M,Cappellaro P

更新日期：2013-01-01 00:00:00

abstract：:Many glasses exhibit fractional power law (FPL) between the mean atomic volume va and the first diffraction peak position q1, i.e. [Formula: see text] with d ≃ 2.5 deviating from the space dimension D = 3, under compression or composition change. What structural change causes such FPL and whether the FPL and d are uni...

journal_title：Nature communications

authors： Zhang H,Qiao K,Han Y

更新日期：2020-04-24 00:00:00