Fixation with even small quantities of glutaraldehyde affects red blood cell surface properties in a cell- and species-dependent manner. Studies by cell partitioning.

abstract：:LGMD (limb-girdle muscular dystrophy) and CMD (congenital muscular dystrophy) are two common forms of neuromuscular disorders which are distinguishable by their age of onset but with probably a similar underlying pathway. In the present study, we report immunohistochemical, Western-blot and genetic analyses in a large...

journal_title：Bioscience reports

authors： Hadj Salem I,Kamoun F,Louhichi N,Rouis S,Mziou M,Fendri-Kriaa N,Makni-Ayadi F,Triki C,Fakhfakh F

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND/AIMS:MicroRNAs (miRNAs) are involved in the pathogenesis of osteoarthritis (OA). The present study aimed to investigate the potential function of miR-122 in the development of OA and its potential molecular mechanisms. METHODS:The expression of miR-122, silent information regulator 1 (SIRT1), collagen II, a...

journal_title：Bioscience reports

authors： Bai Y,Chen K,Zhan J,Wu M

更新日期：2020-06-26 00:00:00

abstract：OBJECTIVE:The present study aimed to construct a diagnosis model for the early differentiation of acute radiation pneumonitis (ARP) and infectious pneumonitis based on multiple parameters. METHODS:The present study included data of 152 patients admitted to the Department of Radiochemotherapy, Tangshan People's Hospita...

journal_title：Bioscience reports

authors： Wang Z,Wu Q,Dong L,Fu H,Liu Q

更新日期：2020-04-30 00:00:00

abstract：:We assessed the relationship between the volume of epicardial adipose tissue and long-term outcomes in patients with coronary heart disease (CHD) undergoing percutaneous coronary intervention (PCI). The patients with CHD were followed for at least 2 years after PCI. The epicardial adipose tissue volume (EATV) was meas...

journal_title：Bioscience reports

authors： Lu C,Jia H,Wang Z

更新日期：2019-05-07 00:00:00

abstract：:The concentration of Na+ and K+ and the pH in the cytoplasm of Lettré cells was measured by monitoring the net flux of H+, Na+, or K+ across the plasma membrane which had been rendered permeable to these ions by the action of Sendai virus. Ion flux was measured directly by analysis of cell composition, or indirectly b...

journal_title：Bioscience reports

authors： Bashford CL,Alder G,Micklem KJ,Pasternak CA

更新日期：1983-07-01 00:00:00

abstract：:N-(2-Hydroxypropyl)methacrylamide copolymers bearing oligopeptide side-chains terminating in p-nitroaniline (NAp) were incubated with rat liver lysosomal enzymes in the presence of the thiol glutathione, and the rate of p-nitroaniline release was measured. Twelve of the 16 side-chains investigated were hydrolysed to r...

journal_title：Bioscience reports

authors： Duncan R,Cable HC,Lloyd JB,Rejmanová P,Kopecek J

更新日期：1982-12-01 00:00:00

abstract：:Fatty-acid synthesis has been measured in vivo with 3H2O in cafeteria-fed rats exhibiting diet-induced thermogenesis. Synthesis was decreased in brown adipose tissue, the liver, white adipose tissue, and the carcass of the cafeteria-fed animals compared to rats fed the normal stock diet. Whole-body synthesis was also ...

journal_title：Bioscience reports

authors： Rothwell NJ,Stock MJ,Trayhurn P

更新日期：1983-03-01 00:00:00

abstract：:The sites and extents of bisulphite-mediated deamination of cytidine residues in HeLa-cell 5.8 S rRNA within the 5.8 S / 28 S rRNA complex have been determined. Comparison of these data with equivalent data for isolated ('unbound') 5.8 S rRNA suggests that the conformation of several cytidine residues, including inter...

journal_title：Bioscience reports

authors： Kelly JM,Goddard JP

更新日期：1981-05-01 00:00:00

abstract：:Background: Endometrial carcinoma (EC) still threatens the health of women. Thus, to explore how long intergenic non-protein coding RNA 01220 regulates the development of EC.Methods: Whole genome expression profile data of EC and paracancerous tissues in TCGA database were downloaded. LINC01220 expression in EC and pa...

journal_title：Bioscience reports

authors： Li Y,Kong C,Wu C,Wang Y,Xu B,Liang S,Ying X

更新日期：2019-07-25 00:00:00

abstract：:Purpose: Wilson's disease (WD) is a genetic disorder of copper metabolism with pathological copper accumulation in the brain. The purpose of the present study was to evaluate the relationship between the damaged white matter and the impaired cognitive function in WD patients. Materials and methods: Thirty WD adolescen...

journal_title：Bioscience reports

authors： Dong T,Yang WM,Wu MC,Zhang J,Huang P,Xu CS,Wang AQ,Kuang CJ,Gao ZL

更新日期：2019-03-15 00:00:00

abstract：:Isoliquiritigenin (ISL), a natural product isolated from licorice root, exhibits anti-gastric cancer effects. However, applications of ISL are still limited in clinical practice due to its poor bioavailability. To discovery of more effective anti-gastric cancer agents based on ISL, aldol condensation reaction was appl...

journal_title：Bioscience reports

authors： Huang F,Wang J,Xu Y,Zhang Y,Xu N,Yin L

更新日期：2020-06-26 00:00:00

abstract：:Artocarpus incisa (breadfruit) seeds contain three different lectins (Frutalin, Frutapin (FTP) and Frutackin) with distinct carbohydrate specificities. The most abundant lectin is Frutalin, an α-D-galactose-specific carbohydrate-binding glycoprotein with antitumour properties and potential for tumour biomarker discove...

journal_title：Bioscience reports

authors： de Sousa FD,da Silva BB,Furtado GP,Carneiro IS,Lobo MDP,Guan Y,Guo J,Coker AR,Lourenzoni MR,Guedes MIF,Owen JS,Abraham DJ,Monteiro-Moreira ACO,Moreira RA

更新日期：2017-07-21 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) is a life-threatening chronic cardiopulmonary disorder. However, studies providing PAH-related gene expression profiles are scarce. To identify hub genes involved in PAH, we investigate two microarray data sets from gene expression omnibus (GEO). A total of 150 differentially expr...

journal_title：Bioscience reports

authors： Ma Y,Chen SS,Feng YY,Wang HL

更新日期：2020-09-30 00:00:00

abstract：:Radiotherapy is the primary treatment option for nasopharyngeal carcinoma (NPC). Local recurrence and metastasis caused by radioresistance become a bottleneck of curative effect for patients with NPC. Currently, serum predictive biomarkers of radioresistance are scare. We enrolled NPC patients, who underwent radiother...

journal_title：Bioscience reports

authors： Zhang G,Zhang K,Li C,Li Y,Li Z,Li N,Zhou Q,Shen L

更新日期：2019-05-14 00:00:00

abstract：:Fanconi Anemia (FA) is a rare genetic disorder characterized by developmental defects, bone marrow failure and high predisposition to cancer. The FA DNA repair pathway is required in humans to coordinate repair of DNA interstrand cross-links. The central event in the activation of the pathway is the monoubiquitination...

journal_title：Bioscience reports

authors： Frost MG,Mazloumi Aboukheili AM,Toth R,Walden H

更新日期：2020-06-26 00:00:00

abstract：:Guanylate kinase is an essential and conserved enzyme in nucleotide biosynthetic pathway that transfers phosphoryl group of ATP to GMP for yielding GDP. Here, we report the phosphorylation of guanylate kinase from Mycobacterium tuberculosis (mGmk) by eukaryotic-type Ser/Thr kinase, PknA. Mass spectrometric studies ide...

journal_title：Bioscience reports

authors： S Yadav G,K Ravala S,Kachhap S,Thakur M,Roy A,Singh B,Karthikeyan S,K Chakraborti P

更新日期：2017-11-15 00:00:00

abstract：:Prefoldin subunits (PFDN), primarily known for co-chaperone function associated with cytoskeletal rearrangement, have been found involved in epithelial-mesenchymal transition (EMT) and cancer progression. However, studies focusing on the roles of PFDN in gastric cancer (GC) remain limited. The present study aims to ev...

journal_title：Bioscience reports

authors： Yesseyeva G,Aikemu B,Hong H,Yu C,Dong F,Sun J,Zang L,Zheng M,Ma J

更新日期：2020-02-28 00:00:00

abstract：:Trypsin-releasable glycosaminoglycans from the luminal surface of intact pig aorta were measured following metabolic labelling with [35S]sulphate. Chondroitin sulphate was found to be present at a surface density equal to that already established for heparan sulphate (5 X 10(11) chains per cm2). This result was confir...

journal_title：Bioscience reports

authors： Hale G,Streeter HB,Hann AC,Gacesa P,Wusteman FS

更新日期：1987-03-01 00:00:00

abstract：:PU box binding protein (PU.1) is a critical transcription factor involved in many pathological processes. However, its exact role in activation of hepatic stellate cells (HSCs) and liver fibrosis was rarely reported. Here, we found that, in HSCs of PU.1+/- mice, Sirt1 mRNA expression was not changed but Sirt1 protein ...

journal_title：Bioscience reports

authors： Liu Q,Zhang Y,Yang S,Wu Y,Wang J,Yu W,Liu Y

更新日期：2017-12-12 00:00:00

abstract：:Ovarian cancer is one of the most common gynecological cancers with a high mortality rate in females. Chromatin target of protein arginine methyltransferase (CHTOP) is an important intracellular protein that regulates the transcriptional activation of several oncogenic genes in glioblastomagenesis and controls mature ...

journal_title：Bioscience reports

authors： Feng X,Li L,Wang L,Luo S,Bai X

更新日期：2019-04-16 00:00:00

abstract：:The effect of carbamylcholine and the calcium ionophore A23187 on catecholamine release and intracellular free calcium, [Ca2+]i, in bovine adrenal chromaffin cells was determined. At 10(-4) M carbamylcholine maximal release occurred with an accompanying increase in [Ca2+]i from a basal level of 168 nM to less than 300...

journal_title：Bioscience reports

authors： Burgoyne RD

更新日期：1984-07-01 00:00:00

abstract：:The growth arrest special 5 (GAS5), as a research hotspot of long noncoding RNAs (lncRNAs), has been reported to be associated with colorectal cancer (CRC). However, the association between polymorphisms in GAS5 and the risk of CRC was not clear. In the present study, a case-control study in 1078 CRC patients and 1175...

journal_title：Bioscience reports

authors： Wang Y,Wu S,Yang X,Li X,Chen R

更新日期：2019-04-16 00:00:00

abstract：:A family of artificial proteins, named αRep, based on a natural family of helical repeat was previously designed. αRep members are efficiently expressed, folded and extremely stable proteins. A large αRep library was constructed creating proteins with a randomized interaction surface. In the present study, we show tha...

journal_title：Bioscience reports

authors： Chevrel A,Urvoas A,Li de la Sierra-Gallay I,Aumont-Nicaise M,Moutel S,Desmadril M,Perez F,Gautreau A,van Tilbeurgh H,Minard P,Valerio-Lepiniec M

更新日期：2015-06-12 00:00:00

abstract：:The sodium contents of beta-cell-rich pancreatic islets from ob/ob-mice were measured with an integrating flame photometer. After washing to an apparent steady state with different types of ice-cold media, islets incubated in the absence of glucose contained 79-108 mmol sodium kg-1 dry weight. Exposure to glucose resu...

journal_title：Bioscience reports

authors： Wesslén N,Bergsten P,Hellman B

更新日期：1986-11-01 00:00:00

abstract：:Calmodulin (CaM)-like activity was detected in human serum and foetal calf serum, with an activity 10 times more than that detectable in plasma. Serum CaM was largely accounted for by release from human platelets as confirmed by both radioimmunoassay and sodium-dodecyl-sulphate/polyacrylamide-gel electrophoresis of Ca...

journal_title：Bioscience reports

authors： Mac Neil S,Walker SW,Seid J,Tomlinson S

更新日期：1984-08-01 00:00:00

abstract：:Virus replication inhibitory peptide (carbobenzoxy-D-Phe-L-PheGly) was shown to be a potent specific inhibitor of the replication of paramyxovirus and myxovirus (Richardson, Scheid and Choppin (1980), Virology 105, 205-222). This peptide inhibits the membrane fusing activity of a viral glycoprotein. Many agents which ...

journal_title：Bioscience reports

authors： Epand RM

更新日期：1986-07-01 00:00:00

abstract：:Gamma- and delta-isomers of hexachlorocyclohexane caused marked decreases in the levels of radioactive phospholipids, and increases in the levels of [3H]arachidonate incorporated into free fatty acids in rat renal tubular cells. The increased radioactivity of free fatty acids arises from the decrease of [3H]arachidona...

journal_title：Bioscience reports

authors： Puente-Fraga JC,López-Aparicio P,Senar S,Recio MN,Pérez-Albarsanz MA

更新日期：1995-08-01 00:00:00

abstract：:Western blotting was used as a powerful alternative to immunoprecipitation for the detection of the simian virus 40 (SV40) large tumor (T) antigen. After resolution by electrophoresis on a SDS-polyacrylamide gel of a [35S]methionine labeled crude extract from SV40 infected monkey kidney cells, the separated proteins w...

journal_title：Bioscience reports

authors： Dietrich JB

更新日期：1985-02-01 00:00:00

abstract：:eNOS (endothelial nitric oxide synthase) contains a MAPK (mitogen-activated protein kinase)-binding site associated with a major eNOS control element. Purified ERK (extracellular-signal-regulated kinase) phosphorylates eNOS with a stoichiometry of 2-3 phosphates per eNOS monomer. Phosphorylation decreases NO synthesis...

journal_title：Bioscience reports

authors： Salerno JC,Ghosh DK,Razdan R,Helms KA,Brown CC,McMurry JL,Rye EA,Chrestensen CA

更新日期：2014-09-17 00:00:00

abstract：:Kinesin family member 14 (KIF14) is a member of kinesin family proteins which have been found to be dysregulated in various cancer types. However, the expression of KIF14 and its potential prognostic significance have not been investigated in cervical cancer. Real-time PCR was performed to assess the expression levels...

journal_title：Bioscience reports

authors： Wang W,Shi Y,Li J,Cui W,Yang B

更新日期：2016-04-05 00:00:00