Influence of paramagnetic melanin on the MRI contrast in melanoma: a combined high-field (11.7 T) MRI and EPR study.

abstract：:Optical fluorescence imaging has been developed as an aid to intraoperative diagnosis to improve surgical and endoscopic procedures. Compared with other intraoperative imaging methods, it is lower in cost, has a high safety margin, is portable and easy to use. γ-glutamyl hydroxymethyl rhodamine green (gGlu-HMRG) is a ...

journal_title：Contrast media & molecular imaging

authors： Harada T,Nakamura Y,Sato K,Nagaya T,Choyke PL,Seto Y,Kobayashi H

更新日期：2016-11-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2017/7368384.]. ...

journal_title：Contrast media & molecular imaging

authors： Tse JJ,Dunmore-Buyze PJ,Drangova M,Holdsworth DW

更新日期：2018-08-23 00:00:00

abstract：:Recent reports have claimed a superior performance of HEPES buffer in comparison to alternative buffer systems for (67/68) Ga labeling in aqueous media. In this paper we report spectroscopic ((1) H and (71) Ga NMR), radiochemical, mass spectrometry and theoretical modeling studies on the Ga(3+)/HEPES system (HEPES = N...

journal_title：Contrast media & molecular imaging

authors： Martins AF,Prata MI,Rodrigues SP,Geraldes CF,Riss PJ,Amor-Coarasa A,Burchardt C,Kroll C,Roesch F

更新日期：2013-05-01 00:00:00

abstract：:In this study we report the development of a bioconjugate between superparamagnetic iron oxide nanoparticles and Phl p5a (one of the major allergens from grass pollen). The bioconjugate also contains an optical probe (Alexa647) conjugated to the nanoparticle via biotin-streptavidin association. We show that this conju...

journal_title：Contrast media & molecular imaging

authors： Herranz F,Schmidt-Weber CB,Shamji MH,Narkus A,Ruiz-Cabello J,Vilar R

更新日期：2012-07-01 00:00:00

abstract：:Multimodal nanoprobes are highly demanded for biomedical imaging applications to enhance the reliability of the diagnostic results. Among different types of nano-objects, ultrasmall silica gadolinium nanoparticle (SiGdNP) appears as a safe, effective, and versatile platform for this purpose. In this study, a new metho...

journal_title：Contrast media & molecular imaging

authors： Tran VL,Thakare V,Natuzzi M,Moreau M,Oudot A,Vrigneaud JM,Courteau A,Louis C,Roux S,Boschetti F,Denat F,Tillement O,Lux F

更新日期：2018-11-01 00:00:00

abstract：:The over-expression of sialic acid on the surface of cancer cells compared with normal ones makes this nine-carbon sugar an attractive biomarker for molecular diagnosis and therapy. Here, we describe a study on the molecular recognition of sialic acid end groups on the surface of human glioma cells by (160)Tb-DTPA-EN(...

journal_title：Contrast media & molecular imaging

authors： Djanashvili K,Koning GA,van der Meer AJ,Wolterbeek HT,Peters JA

更新日期：2007-01-01 00:00:00

abstract：:The aim of this work was to investigate the MRI findings on tumor xenografts induced in nude mice by the inoculation of human pancreatic cancer cells labeled with superparamagnetic iron oxide (SPIO), and to monitor the kinetics of SPIO distribution in tumor xenografts. The labeled cancer cells were subcutaneously inoc...

journal_title：Contrast media & molecular imaging

authors： Wu CY,Pu Y,Liu G,Shao Y,Ma QS,Zhang XM

更新日期：2012-01-01 00:00:00

abstract：:An experimental setup consisting of a hollow fiber module (HFM) was developed for the in vitro study of contrast agent (CA) permeability. Controllable flow and known fiber characteristics allowed permeability studies under well-defined conditions with CAs of different molecular weight (MW). In the MRI experiments perf...

journal_title：Contrast media & molecular imaging

authors： Heilmann M,Vautier J,Robert P,Volk A

更新日期：2009-03-01 00:00:00

abstract：:Advances in regenerative medicine are rapidly transforming healthcare. A cornerstone of regenerative medicine is the introduction of cells that were grown or manipulated in vitro. Key questions that arise after these cells are re-introduced are: whether these cells are localized in the appropriate site; whether cells ...

journal_title：Contrast media & molecular imaging

authors： Modo M,Kolosnjaj-Tabi J,Nicholls F,Ling W,Wilhelm C,Debarge O,Gazeau F,Clement O

更新日期：2013-11-01 00:00:00

abstract：:The purpose of this study was to determine if parameters derived from diffusion-weighted (DW-) and dynamic contrast-enhanced (DCE-) magnetic resonance imaging (MRI) can help to assess early response to peptide receptor radionuclide therapy (PRRT) with 90Y-DOTATOC in neuroendocrine hepatic metastases (NET-HM). Twenty p...

journal_title：Contrast media & molecular imaging

authors： Weikert T,Maas OC,Haas T,Klarhöfer M,Bremerich J,Forrer F,Sauter AW,Sommer G

更新日期：2019-11-11 00:00:00

abstract：:An important challenge in medical diagnostics is to design all-in-one contrast agents that can be detected with multiple techniques such as magnetic resonance imaging (MRI), X-ray computed tomography (CT), positron emission tomography (PET), single photon emission tomography (SPECT) or fluorescence imaging (FI). Altho...

journal_title：Contrast media & molecular imaging

authors： van Schooneveld MM,Cormode DP,Koole R,van Wijngaarden JT,Calcagno C,Skajaa T,Hilhorst J,'t Hart DC,Fayad ZA,Mulder WJ,Meijerink A

更新日期：2010-07-01 00:00:00

abstract：:Stem cells, cancer cells and immune cells were labeled by co-incubation with a new ultra-small iron oxide nanoparticle called Molday ION Rhodamine-B (MIRB). Iron staining, fluorescence imaging, transmission electron microscopy and flow cytometry were used to assess cell viability, function and labeling efficiency. Thi...

journal_title：Contrast media & molecular imaging

authors： McFadden C,Mallett CL,Foster PJ

更新日期：2011-11-01 00:00:00

abstract：Objective:To synthesize 68Ga-Glu-urea-Lys(Ahx)-HBED-CC (68Ga-PSMA-11) with a synthesis module and investigate PET-CT imaging to monitor PSMA expression during prostate cancer (PCa) progression and tumor growth in mice bearing subcutaneous PCa xenografts. Method:The radiochemical purity and stability of  68Ga-PSMA-11 w...

journal_title：Contrast media & molecular imaging

authors： Wang Y,Shao G,Wu J,Cui C,Zang S,Qiu F,Jia R,Wang Z,Wang F

更新日期：2018-04-26 00:00:00

abstract：Aim:To evaluate reproducibility and stability of radiomic features as effects of the use of different volume segmentation methods and reconstruction settings. The potential of radiomics in really capturing the presence of heterogeneous tumor uptake and irregular shape was also investigated. Materials and Methods:An an...

journal_title：Contrast media & molecular imaging

authors： Gallivanone F,Interlenghi M,D'Ambrosio D,Trifirò G,Castiglioni I

更新日期：2018-09-10 00:00:00

abstract：:The gonadotropin-releasing hormone (GnRH) receptor is overexpressed in the majority of tumors of the human reproductive system. The purpose of this study was to develop an 18F-labeled peptide for tumor GnRH receptor imaging. In this study, the GnRH (pGlu1-His2-Trp3-Ser4-Tyr5-Gly6-Leu7-Arg8-Pro9-Gly10-NH2) peptide anal...

journal_title：Contrast media & molecular imaging

authors： Huang S,Li H,Han Y,Fu L,Ren Y,Zhang Y,Li Y,Sun P,Wang M,Wu H,Wang Q,Hu K

更新日期：2019-03-07 00:00:00

abstract：:The purpose was to investigate whether MnCl(2) can serve as an MRI contrast agent to detect chronic cryoinjury infarction in pigs in vivo and whether MnCl(2) causes significant hemodynamic disturbances. Hearts were subjected to a topical 2 min cryothermia to establish myocardial infarction (MI). Thereafter GdDTPA-enha...

journal_title：Contrast media & molecular imaging

authors： Yang Y,de Gervai PD,Sun J,Gruwel ML,Kupriyanov V

更新日期：2011-11-01 00:00:00

abstract：:Inorganic doping was used to create flexible, paramagnetic nanoparticle contrast agents for in vivo molecular magnetic resonance imaging (MRI) with low transverse relaxivity (r2). Most nanoparticle contrast agents formed from superparamagnetic metal oxides are developed with high r2. While sensitive, they can have lim...

journal_title：Contrast media & molecular imaging

authors： Clavijo Jordan MV,Beeman SC,Baldelomar EJ,Bennett KM

更新日期：2014-09-01 00:00:00

abstract：:A new high-throughput MRI method for screening chemical exchange saturation transfer (CEST) agents is demonstrated, allowing simultaneous testing of multiple samples with minimal attention to sample configuration and shimming of the main magnetic field (B(0)). This approach, which is applicable to diamagnetic, paramag...

journal_title：Contrast media & molecular imaging

authors： Liu G,Gilad AA,Bulte JW,van Zijl PC,McMahon MT

更新日期：2010-05-01 00:00:00

abstract：:The aim of the present study was to test alginate gels of different compositions as a system for controlled release of manganese ions (Mn(2+)) for application in manganese-enhanced MRI (MEMRI), in order to circumvent the challenge of achieving optimal MRI resolution without resorting to high, potentially cytotoxic dos...

journal_title：Contrast media & molecular imaging

authors： Mørch YA,Sandvig I,Olsen O,Donati I,Thuen M,Skjåk-Braek G,Haraldseth O,Brekken C

更新日期：2012-03-01 00:00:00

abstract：:Magnetic fluid hyperthermia (MFH) with chemically synthesized nanoparticles is currently used in clinical trials as it destroys tumor cells with an extremely localized deposition of thermal energy. In this paper, we investigated an MFH protocol based on magnetic nanoparticles naturally produced by magnetotactic bacter...

journal_title：Contrast media & molecular imaging

authors： Mannucci S,Tambalo S,Conti G,Ghin L,Milanese A,Carboncino A,Nicolato E,Marinozzi MR,Benati D,Bassi R,Marzola P,Sbarbati A

更新日期：2018-07-11 00:00:00

abstract：Objective:To provide a clinically relevant overview of the analytical interference by contrast agents (CA) in laboratory blood test measurements. Materials and Methods:The effects of five CAs, gadobutrol, gadoterate meglumine, gadoxetate disodium, iodixanol, and iomeprol, were studied on the 29 most frequently perform...

journal_title：Contrast media & molecular imaging

authors： Otnes S,Fogh-Andersen N,Rømsing J,Thomsen HS

更新日期：2017-04-10 00:00:00

abstract：:Recent advances in artificial intelligence (AI) and deep learning (DL) have impacted many scientific fields including biomedical maging. Magnetic resonance imaging (MRI) is a well-established method in breast imaging with several indications including screening, staging, and therapy monitoring. The rapid development a...

journal_title：Contrast media & molecular imaging

authors： Meyer-Bäse A,Morra L,Meyer-Bäse U,Pinker K

更新日期：2020-08-28 00:00:00

abstract：:Various contrast agents (Magnevist, Gadovist and Multihance) loaded into polymeric nanocapsules were synthesized by the inverse miniemulsion technique. The relaxivity of the resultant contrast agents was assessed at 1.5 T magnetic field strength. The ionic relaxivity of the contrast agents could at least be maintained...

journal_title：Contrast media & molecular imaging

authors： Sharma S,Paiphansiri U,Hombach V,Mailänder V,Zimmermann O,Landfester K,Rasche V

更新日期：2010-03-01 00:00:00

abstract：:Self-aggregation of dyes even at low concentrations poses a considerable challenge in preparing sufficiently bright molecular probes for in vivo imaging, particularly in the conjugation of near infrared cyanine dyes to polypeptides with multiple labeling sites. Such self-aggregation leads to a significant energy trans...

journal_title：Contrast media & molecular imaging

authors： Zhegalova NG,He S,Zhou H,Kim DM,Berezin MY

更新日期：2014-09-01 00:00:00

abstract：:Photoacoustic imaging is an emerging imaging modality for noninvasive detection of tissue structural and functional anomalies. Multifunctional microbubbles (MBs) and nanobubbles (NBs) are contrast agents integrating multiple disease-targeting, imaging and therapeutic functions. Multifunctional MBs and NBs represent an...

journal_title：Contrast media & molecular imaging

authors： Xu RX

更新日期：2011-09-01 00:00:00

abstract：Objectives:Bone ischemia and necrosis are challenging to treat, requiring investigation of native and engineered bone revascularisation processes through advanced imaging techniques. This study demonstrates an experimental two-step method for precise bone and vessel analysis in native bones or vascularised bone grafts ...

journal_title：Contrast media & molecular imaging

authors： Sutter S,Todorov A,Ismail T,Haumer A,Fulco I,Schulz G,Scherberich A,Kaempfen A,Martin I,Schaefer DJ

更新日期：2017-04-23 00:00:00

abstract：:Knowledge of the longitudinal and transverse relaxation times (T(1) and T(2)) of water protons in an aqueous solution of an MRI contrast agent is essential for its characterization. These parameters can be measured at low field on low resolution spectrometers or at high field on high resolution spectrometers. The reli...

journal_title：Contrast media & molecular imaging

authors： Henoumont C,Laurent S,Vander Elst L

更新日期：2009-11-01 00:00:00

abstract：PURPOSE:Regional wall thickening measurement by delayed contrast MRI may assess myocardial viability and functional recovery of ischemic cardiomyopathy. MATERIALS AND METHODS:Delayed contrast MRI data was used in 40 patients with significant coronary artery disease and severe left ventricular dysfunction. Regional wal...

journal_title：Contrast media & molecular imaging

authors： Sharma R,Katz JK

更新日期：2009-01-01 00:00:00

abstract：Purpose:Several meta-analyses have reported data about the diagnostic performance of positron emission tomography or positron emission tomography/computed tomography (PET or PET/CT) with different radiotracers in patients with suspicious lung cancer (LC) or pleural tumours (PT). This review article aims at providing an...

journal_title：Contrast media & molecular imaging

authors： Lococo F,Muoio B,Chiappetta M,Nachira D,Petracca Ciavarella L,Margaritora S,Treglia G

更新日期：2020-04-25 00:00:00

abstract：:To date, the combination of histological sectioning, staining, and microscopic assessment of the 2D sections is still the golden standard for structural and compositional analysis of biological tissues. X-ray microfocus computed tomography (microCT) is an emerging 3D imaging technique with high potential for 3D struct...

journal_title：Contrast media & molecular imaging

authors： de Bournonville S,Vangrunderbeeck S,Kerckhofs G

更新日期：2019-02-28 00:00:00