Current Status and Future Perspectives of Artificial Intelligence in Magnetic Resonance Breast Imaging.

abstract：:The development of molecular probes and novel imaging modalities, allowing better resolution and specificity, is associated with an increased potential for molecular imaging of atherosclerotic plaques especially in basic and pre-clinical research applications. In that context, a photoacoustic molecular probe based on ...

journal_title：Contrast media & molecular imaging

authors： Rouleau L,Berti R,Ng VW,Matteau-Pelletier C,Lam T,Saboural P,Kakkar AK,Lesage F,Rhéaume E,Tardif JC

更新日期：2013-01-01 00:00:00

abstract：:Melanoma is the most dangerous form of skin cancer and its incidence is rising each year. Because the current methods of diagnosis based on the visual aspect of the tumor show limitations, several new techniques are emerging to help in this diagnosis, amongst which are magnetic resonance imaging (MRI) and electron par...

journal_title：Contrast media & molecular imaging

authors： Godechal Q,Mignion L,Karroum O,Magat J,Danhier P,Morandini R,Ghanem GE,Leveque P,Gallez B

更新日期：2014-03-01 00:00:00

abstract：:We evaluated the difference in the status of dopamine transporters (DATs) depending on Parkinsonism, cerebellar, and autonomic features using F-18 FP-CIT positron emission tomography (PET) in multiple system atrophy with cerebellar ataxia (MSA-C). We also assessed whether the DAT PET could be useful in the management ...

journal_title：Contrast media & molecular imaging

authors： Jeong YJ,Cheon SM,Kang DY,Kim JW

更新日期：2017-11-29 00:00:00

abstract：:Knowledge of the longitudinal and transverse relaxation times (T(1) and T(2)) of water protons in an aqueous solution of an MRI contrast agent is essential for its characterization. These parameters can be measured at low field on low resolution spectrometers or at high field on high resolution spectrometers. The reli...

journal_title：Contrast media & molecular imaging

authors： Henoumont C,Laurent S,Vander Elst L

更新日期：2009-11-01 00:00:00

abstract：:An observational study was set up to assess the feasibility of [18F]FPRGD2 PET/CT for imaging patients with multiple myeloma (MM) and to compare its detection rate with low dose CT alone and combined [18F]NaF/[18F]FDG PET/CT images. Four patients (2 newly diagnosed patients and 2 with relapsed MM) were included and un...

journal_title：Contrast media & molecular imaging

authors： Withofs N,Cousin F,De Prijck B,Bonnet C,Hustinx R,Gambhir SS,Beguin Y,Caers J

更新日期：2017-07-27 00:00:00

abstract：:Chemical exchange saturation transfer (CEST) imaging is an emerging MRI technique relying on the use of endogenous or exogenous molecules containing exchangeable proton pools. The heterogeneity of the water resonance frequency offset plays a key role in the occurrence of artifacts in CEST-MR images. To limit this draw...

journal_title：Contrast media & molecular imaging

authors： Stancanello J,Terreno E,Castelli DD,Cabella C,Uggeri F,Aime S

更新日期：2008-07-01 00:00:00

abstract：:The use of superparamagnetic iron oxide (SPIO) for labeling cells holds great promise for clinically applicable cell tracking using magnetic resonance imaging. For clinical application, an effectively and specifically labeled cell preparation is highly desired (i.e. a large amount of intracellular iron and a negligibl...

journal_title：Contrast media & molecular imaging

authors： van Buul GM,Farrell E,Kops N,van Tiel ST,Bos PK,Weinans H,Krestin GP,van Osch GJ,Bernsen MR

更新日期：2009-09-01 00:00:00

abstract：:The gonadotropin-releasing hormone (GnRH) receptor is overexpressed in the majority of tumors of the human reproductive system. The purpose of this study was to develop an 18F-labeled peptide for tumor GnRH receptor imaging. In this study, the GnRH (pGlu1-His2-Trp3-Ser4-Tyr5-Gly6-Leu7-Arg8-Pro9-Gly10-NH2) peptide anal...

journal_title：Contrast media & molecular imaging

authors： Huang S,Li H,Han Y,Fu L,Ren Y,Zhang Y,Li Y,Sun P,Wang M,Wu H,Wang Q,Hu K

更新日期：2019-03-07 00:00:00

abstract：:A specific mouse whole body coil and a dedicated gradient system at 4.7 T were coupled with an ultra-fast 3D gradient echo MRI and keyhole reconstruction technique to obtain 3D whole-body dynamic T(1)-weighted or T(2)*-weighted imaging. The technique was used to visualize the real-time distribution of non-targeting T(...

journal_title：Contrast media & molecular imaging

authors： Bled E,Hassen WB,Pourtau L,Mellet P,Lanz T,Schüler D,Voisin P,Franconi JM,Thiaudière E,Miraux S

更新日期：2011-07-01 00:00:00

abstract：Objective:We aimed to propose an automatic method based on Support Vector Machine (SVM) and Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to segment the tumor lesions of head and neck cancer (HNC). Materials and Methods:120 DCE-MRI samples were collected. Five curve features and two principal componen...

journal_title：Contrast media & molecular imaging

authors： Deng W,Luo L,Lin X,Fang T,Liu D,Dan G,Chen H

更新日期：2017-09-07 00:00:00

abstract：:An important challenge in medical diagnostics is to design all-in-one contrast agents that can be detected with multiple techniques such as magnetic resonance imaging (MRI), X-ray computed tomography (CT), positron emission tomography (PET), single photon emission tomography (SPECT) or fluorescence imaging (FI). Altho...

journal_title：Contrast media & molecular imaging

authors： van Schooneveld MM,Cormode DP,Koole R,van Wijngaarden JT,Calcagno C,Skajaa T,Hilhorst J,'t Hart DC,Fayad ZA,Mulder WJ,Meijerink A

更新日期：2010-07-01 00:00:00

abstract：:Sialic acid-binding immunoglobulin-like lectin 9 (Siglec-9) is a ligand of inflammation-inducible vascular adhesion protein-1 (VAP-1). We compared 68Ga-DOTA- and 18F-fluorodeoxyribose- (FDR-) labeled Siglec-9 motif peptides for PET imaging of inflammation. Methods. Firstly, we examined 68Ga-DOTA-Siglec-9 and 18F-FDR-S...

journal_title：Contrast media & molecular imaging

authors： Virtanen H,Silvola JMU,Autio A,Li XG,Liljenbäck H,Hellberg S,Siitonen R,Ståhle M,Käkelä M,Airaksinen AJ,Helariutta K,Tolvanen T,Veres TZ,Saraste A,Knuuti J,Jalkanen S,Roivainen A

更新日期：2017-12-31 00:00:00

abstract：:A generic site-specific conjugation method that generates a homogeneous product is of utmost importance in tracer development for molecular imaging and therapy. We explored the protein-ligation capacity of the enzyme Sortase A to label camelid single-domain antibody-fragments, also known as nanobodies. The versatility...

journal_title：Contrast media & molecular imaging

authors： Massa S,Vikani N,Betti C,Ballet S,Vanderhaegen S,Steyaert J,Descamps B,Vanhove C,Bunschoten A,van Leeuwen FW,Hernot S,Caveliers V,Lahoutte T,Muyldermans S,Xavier C,Devoogdt N

更新日期：2016-09-01 00:00:00

abstract：:Gold nanoparticles coated by gadolinium (III) chelates (Au@DTDTPA) where DTDTPA is a dithiolated bisamide derivative of diethylenetriamine-N,N,N',N'',N''-pentaacetic acid (DTPA), constituted contrast agents for both X-ray computed tomography and magnetic resonance imaging. In an MRI context, highly stable Gd(3+) compl...

journal_title：Contrast media & molecular imaging

authors： Mogilireddy V,Déchamps-Olivier I,Alric C,Laurent G,Laurent S,Vander Elst L,Muller R,Bazzi R,Roux S,Tillement O,Chuburu F

更新日期：2015-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The purpose of this pilot study was to establish the ability of dynamic contrast enhanced computed tomography (DCE-CT) to detect changes in tumor blood flow (BF) and oxygenation induced by vasoactive substances in rats. MATERIALS AND METHODS:Under ultrasound guidance, a fiber-optic probe was g...

journal_title：Contrast media & molecular imaging

authors： Pollard RE,Larson RF

更新日期：2011-01-01 00:00:00

abstract：:Developing agents with 'seek, treat and see' capability is critical for personalized molecular medicine. Those agents will specifically target the disease markers for diagnosis and apply the biologically effective dose for treatment. Retinoids regulate a multitude of biological processes. In addition, retinoic acid ca...

journal_title：Contrast media & molecular imaging

authors： Wang W,Qiu X,Zhang F,Sun J,Cameron AG,Wendt JA,Mawad ME,Ke S

更新日期：2011-07-01 00:00:00

abstract：:Overexpression of the chemokine-4 receptor (CXCR4) in brain tumors is associated with high cancer cell invasiveness. Recently, we reported the preclinical evaluation of 99mTc-CXCR4-L (cyclo-D-Tyr-D-[NMe]Orn[EDDA-99mTc-6-hydrazinylnicotinyl]-Arg-NaI-Gly) as a SPECT radioligand capable of specifically detecting the CXCR...

journal_title：Contrast media & molecular imaging

authors： Vallejo-Armenta P,Santos-Cuevas C,Soto-Andonaegui J,Villanueva-Pérez RM,González-Díaz JI,García-Pérez FO,Arrellano-Zarate A,Luna-Gutiérrez M,Azorín-Vega E,Ocampo-García B,Ferro-Flores G

更新日期：2020-04-27 00:00:00

abstract：Purpose:Several meta-analyses have reported data about the diagnostic performance of positron emission tomography or positron emission tomography/computed tomography (PET or PET/CT) with different radiotracers in patients with suspicious lung cancer (LC) or pleural tumours (PT). This review article aims at providing an...

journal_title：Contrast media & molecular imaging

authors： Lococo F,Muoio B,Chiappetta M,Nachira D,Petracca Ciavarella L,Margaritora S,Treglia G

更新日期：2020-04-25 00:00:00

abstract：:The transplantation of pancreatic islets containing β-cells, which produce insulin, is an alternative approach to the treatment of type 1 diabetes mellitus. The non-invasive visualization of transplanted islets can be performed using MRI; however, this requires labeling of the islets with a suitable contrast agent pri...

journal_title：Contrast media & molecular imaging

authors： Herynek V,Berková Z,Dovolilová E,Jirák D,Kříž J,Girman P,Saudek F,Hájek M

更新日期：2011-07-01 00:00:00

abstract：Objective:To synthesize 68Ga-Glu-urea-Lys(Ahx)-HBED-CC (68Ga-PSMA-11) with a synthesis module and investigate PET-CT imaging to monitor PSMA expression during prostate cancer (PCa) progression and tumor growth in mice bearing subcutaneous PCa xenografts. Method:The radiochemical purity and stability of  68Ga-PSMA-11 w...

journal_title：Contrast media & molecular imaging

authors： Wang Y,Shao G,Wu J,Cui C,Zang S,Qiu F,Jia R,Wang Z,Wang F

更新日期：2018-04-26 00:00:00

abstract：:Quantum dot micelles (pQDs) with a paramagnetic coating are promising nanoparticles for bimodal molecular imaging. Their bright fluorescence allows for optical detection, while their Gd payload enables visualization with contrast-enhanced MRI. A popular approach in molecular MRI is the targeting of abundantly expresse...

journal_title：Contrast media & molecular imaging

authors： Starmans LW,Kok MB,Sanders HM,Zhao Y,Donegá Cde M,Meijerink A,Mulder WJ,Grüll H,Strijkers GJ,Nicolay K

更新日期：2011-03-01 00:00:00

abstract：:The aim of this work was to investigate the MRI findings on tumor xenografts induced in nude mice by the inoculation of human pancreatic cancer cells labeled with superparamagnetic iron oxide (SPIO), and to monitor the kinetics of SPIO distribution in tumor xenografts. The labeled cancer cells were subcutaneously inoc...

journal_title：Contrast media & molecular imaging

authors： Wu CY,Pu Y,Liu G,Shao Y,Ma QS,Zhang XM

更新日期：2012-01-01 00:00:00

abstract：Objective:To provide a clinically relevant overview of the analytical interference by contrast agents (CA) in laboratory blood test measurements. Materials and Methods:The effects of five CAs, gadobutrol, gadoterate meglumine, gadoxetate disodium, iodixanol, and iomeprol, were studied on the 29 most frequently perform...

journal_title：Contrast media & molecular imaging

authors： Otnes S,Fogh-Andersen N,Rømsing J,Thomsen HS

更新日期：2017-04-10 00:00:00

abstract：:Glioblastoma multiforme is the most aggressive form of brain tumor. Early and accurate diagnosis of glioma and its borders is an important step for its successful treatment. One of the promising targets for selective visualization of glioma and its margins is connexin 43 (Cx43), which is highly expressed in reactive a...

journal_title：Contrast media & molecular imaging

authors： Abakumova T,Abakumov M,Shein S,Chelushkin P,Bychkov D,Mukhin V,Yusubalieva G,Grinenko N,Kabanov A,Nukolova N,Chekhonin V

更新日期：2016-01-01 00:00:00

abstract：:Targeted magnetic resonance contrast agents (e.g. iron oxide nanoparticles) have the potential to become highly selective imaging tools. In this context, quantification of the coupled amount of protein is essential for the design of antibody- or antibody fragment-conjugated nanoparticles. Nevertheless, the presence of...

journal_title：Contrast media & molecular imaging

authors： Rimkus G,Bremer-Streck S,Grüttner C,Kaiser WA,Hilger I

更新日期：2011-05-01 00:00:00

abstract：:To date, the combination of histological sectioning, staining, and microscopic assessment of the 2D sections is still the golden standard for structural and compositional analysis of biological tissues. X-ray microfocus computed tomography (microCT) is an emerging 3D imaging technique with high potential for 3D struct...

journal_title：Contrast media & molecular imaging

authors： de Bournonville S,Vangrunderbeeck S,Kerckhofs G

更新日期：2019-02-28 00:00:00

abstract：:Stem cells, cancer cells and immune cells were labeled by co-incubation with a new ultra-small iron oxide nanoparticle called Molday ION Rhodamine-B (MIRB). Iron staining, fluorescence imaging, transmission electron microscopy and flow cytometry were used to assess cell viability, function and labeling efficiency. Thi...

journal_title：Contrast media & molecular imaging

authors： McFadden C,Mallett CL,Foster PJ

更新日期：2011-11-01 00:00:00

abstract：:In vivo molecular imaging with targeted MRI contrast agents will require sensitive methods to quantify local concentrations of contrast agent, enabling not only imaging-based recognition of pathological biomarkers but also detection of changes in expression levels as a consequence of disease development, therapeutic i...

journal_title：Contrast media & molecular imaging

authors： Kok MB,de Vries A,Abdurrachim D,Prompers JJ,Grüll H,Nicolay K,Strijkers GJ

更新日期：2011-01-01 00:00:00

abstract：:Two novel Gd-based contrast agents (CAs) for the molecular imaging of matrix metalloproteinases (MMPs) were synthetized and characterized in vitro and in vivo. These probes were based on the PLG*LWAR peptide sequence, known to be hydrolyzed between Gly and Leu by a broad panel of MMPs. A Gd-DOTA chelate was conjugated...

journal_title：Contrast media & molecular imaging

authors： Gringeri CV,Menchise V,Rizzitelli S,Cittadino E,Catanzaro V,Dati G,Chaabane L,Digilio G,Aime S

更新日期：2012-03-01 00:00:00

abstract：:The aim of this study was to compare intratumoural heterogeneity and longitudinal changes assessed by dynamic contrast-enhanced ultrasound (DCE-US) and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in prostate tumour xenografts. In vivo DCE-US and DCE-MRI were obtained 24 h pre- (day 0) and post- (day...

journal_title：Contrast media & molecular imaging

authors： Arteaga-Marrero N,Rygh CB,Mainou-Gomez JF,Nylund K,Roehrich D,Heggdal J,Matulaniec P,Gilja OH,Reed RK,Svensson L,Lutay N,Olsen DR

更新日期：2015-11-01 00:00:00