Ovum donation--a simplified approach.

Abstract:

:To date, ovum donation (OD) has involved luteinizing hormone (LH) synchronization between recipient and donor for normally cycling women, and a complex steroid replacement regimen given on a sequential and incremental basis for women with primary or secondary ovarian failure. The authors designed a simple hormonal regimen applicable to both normally cycling women starting early in the cycle, and to those with ovarian failure. It consists of administering 2 mg estradiol (E2) valerate orally three or four times daily, augmented with either 100 mg progesterone (P) in ethyl oleate intramuscularly daily or 100 mg oral progesterone (P) orally three times daily, starting on the day preceding the recovery of the donated oocytes. Gamete intrafallopian transfer procedure was undertaken for women with patent tubes and in vitro fertilization for those with obstructed tubes. The authors report their preliminary experience with 17 women who underwent ovum donation.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Serhal PF,Craft IL

doi

10.1016/s0015-0282(16)59354-6

subject

Has Abstract

pub_date

1987-08-01 00:00:00

pages

265-9

issue

2

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(16)59354-6

journal_volume

48

pub_type

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