Abstract：
OBJECTIVE:To determine the probability of detecting the gestational sac of a normal intrauterine pregnancy by vaginal ultrasound at different gestational ages and serum hCG concentrations. DESIGN:Prospective, randomized study. SETTING:Pregnant human volunteers in a university-based clinical research environment. PATIENTS:Women with viable pregnancies who conceived spontaneously or after ovulation induction. INTERVENTIONS:Vaginal ultrasound and serum hCG determinations were performed between 20 and 30 days after conception. The timing of the tests was determined randomly. MAIN OUTCOME MEASURE:Detection of gestational sac. RESULTS:The probability of detecting a gestational sac increased significantly with both gestational age and serum hCG concentration, but the regression on gestational age fitted the data much better than the regression on loge (hCG). The probability of detecting a sac was similar in multiple and singleton pregnancies of the same gestational age but, for a given hCG concentration, the probability of detecting a sac was lower for multiple than for singleton pregnancies because multiple gestations were associated with higher serum hCG concentrations than singleton pregnancies of the same gestational age. CONCLUSION:If it is known, gestational age rather than the serum hCG concentration should be used to determine whether the gestational sac of an intrauterine pregnancy should be detectable by vaginal ultrasound. Failure to image a gestational sac > or = 24 days after conception is presumptive evidence of an ectopic pregnancy. Reliance on serum hCG rather than gestational age may lead to an erroneous diagnosis of ectopic pregnancy in women with multiple pregnancies.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Kadar N,Bohrer M,Kemmann E,Shelden Rdoi
10.1016/s0015-0282(16)56749-1subject
Has Abstractpub_date
1994-06-01 00:00:00pages
1016-20issue
6eissn
0015-0282issn
1556-5653pii
S0015-0282(16)56749-1journal_volume
61pub_type
临床试验,杂志文章,随机对照试验abstract：:This retrospective cohort study compared blastocyst transfers in 136 fresh oocyte donor cycles and 69 autologous cycles using blastocysts derived from culture of thawed bipronuclear oocytes, all with oocytes derived from patients or donors less than 35 years old. The autologous cycles and oocyte donor cycles had simil...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.07.966
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVE:To investigate whether components of the Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway are present and active in human sperm. DESIGN:Comparative study. SETTING:Reproductive biology department. PATIENT(S):Nine sperm donors. INTERVENTION(S):Sperm were exposed to interfer...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(01)01896-9
更新日期：2001-08-01 00:00:00
abstract：:The ability to predict the outcome of a pregnancy of unknown location (PUL) has been extensively studied over the past decade. Between 8%-14% of PULs will develop into ectopic pregnancies (EP), and therefore the need to confirm pregnancy location is not without good reason. Strategies to predict EP in the PUL populati...
journal_title：Fertility and sterility
pub_type： 评论,杂志文章
doi：10.1016/j.fertnstert.2012.09.032
更新日期：2012-11-01 00:00:00
abstract：OBJECTIVE:To determine the effects of dietary carrots and retinoic acid on P secretion in the in vitro perfused rabbit ovary. DESIGN:Controlled experiment. SETTING:Laboratory. SUBJECTS:Sexually mature New Zealand white rabbits. INTERVENTION(S):Experiments were done in vitro using an isolated rabbit ovarian perfusio...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(97)81529-4
更新日期：1997-08-01 00:00:00
abstract：OBJECTIVE:To analyze the activity of cytosolic carbonic anhydrases (CAs) during the pre- and postimplantation stages of pregnancy in mice. Furthermore, to investigate the CA activity in mice in which abortion was induced by injection of substance P. DESIGN:Controlled animal experiment. SETTING:University research lab...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2004.03.033
更新日期：2004-10-01 00:00:00
abstract：:A laparotomy was performed in 40 rats and the cecum was subjected to a standardized trauma. Half the rats were treated with oxyphenbutazone in a dose of 40 mg/kg body weight daily for 14 days. The remaining 20 rats served as controls. All of the rats were killed 2 weeks after the laparotomy, and the number of intraper...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)42731-7
更新日期：1977-08-01 00:00:00
abstract：OBJECTIVE:To describe an ovarian abscess presenting very late after oocyte retrieval for IVF with several unusual clinical features. DESIGN:Case report. SETTING:Academic medical center. PATIENT(S):A 35-year-old nulliparous woman underwent IVF with uncomplicated transvaginal oocyte retrieval (TVOR), resulting in a di...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.12.045
更新日期：2006-07-01 00:00:00
abstract：OBJECTIVE:To determine Müllerian inhibiting substance (MIS) levels in follicular fluid (FF) and sera of IVF patients. DESIGN:Prospective study. SETTING:Fertility center. PATIENT(S):Sixty-six patients: 20 with tubal factor infertility, 17 with polycystic ovary syndrome (PCOS), and 29 with endometriosis. INTERVENTION...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(97)81417-3
更新日期：1997-05-01 00:00:00
abstract：OBJECTIVE:To report on chronic urinary retention after surgery for deep endometriosis and the possible risk factors for this complication. DESIGN:Descriptive study. SETTING:University hospital. PATIENT(S):Four patients with deep endometriosis who developed this complication. INTERVENTION(S):Laparoscopic surgery, in...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2010.07.1043
更新日期：2011-02-01 00:00:00
abstract：OBJECTIVE:To examine the factors influencing the development of adhesions after laparoscopic myomectomy (LM) and the efficacy of adhesion-preventing agents. DESIGN:Prospective nonrandomized study. SETTING:University-affiliated hospital. PATIENT(S):Three hundred seventy-two patients who underwent LM alone by the same...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/j.fertnstert.2007.05.021
更新日期：2008-05-01 00:00:00
abstract：OBJECTIVE:To assess the effects of age on the hormonal, metabolic, and ultrasonographic features of polycystic ovary syndrome (PCOS). DESIGN:Observational study. SETTING:University department of obstetrics and gynecology. PATIENT(S):Patients with PCOS (n = 1,212) and healthy women (n = 254). INTERVENTION(S):None. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2011.11.041
更新日期：2012-02-01 00:00:00
abstract：:In 6-day pregnant New Zealand White rabbits dosed intravenously with 3H-nicotine, the 3H-activity in the uterine fluid was approximately 5 to 11 times greater than that in the plasma at the corresponding times; 3H-nicotine itself accounted for most of this radioactivity. Dichlorodiphenyltrichloroethane (DDT) also accu...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1976-10-01 00:00:00
abstract：OBJECTIVE:To review our experience with low-dose IM methotrexate for the medical management of ectopic pregnancy (EP). DESIGN:Retrospective chart review. SETTING:Magee-Womens Hospital, Pittsburgh, Pennsylvania. PATIENT(S):The first 50 women treated by the resident service in whom EP was diagnosed and treated with me...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(97)00284-7
更新日期：1997-10-01 00:00:00
abstract：OBJECTIVE:To assess the capacity of human frozen-thawed ovarian follicles matured in xenografts to form metaphase II (MII) oocytes after xenotransplantation and exogenous stimulation. DESIGN:Prospective controlled animal study. SETTING:University hospital gynecology research unit. PATIENT(S):Ovarian fragments were o...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2014.01.038
更新日期：2014-05-01 00:00:00
abstract：:Nineteen vasectomized men were followed for 21 to 42 months after surgery, and their sera were tested for the presence of HL-A lymphocytoxic antibodies. In a previous study, the sera of two of these men had shown a definite increase in serum reactivity 6 to 12 months after surgery. Only one of the nineteen tested in t...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)42494-5
更新日期：1977-04-01 00:00:00
abstract：:Our rapid staining method, accomplished by adding the vital fluorochrome bisbenzimide (Hoechst 33342) directly into the sperm droplet before fertilization, eases visual interpretation of sperm penetration and decondensation. For both within- and between-experiment comparisons, inclusion of bisbenzimide did not influen...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:Effects of single subcutaneous doses (1, 5, 20, and 100 micrograms) of nafarelin, a potent gonadotropin-releasing hormone agonist, on the physiologic events of the human menstrual cycle were studied in 28 normal women. Nafarelin entered the circulation rapidly after injection. Peak concentrations were observed within ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)48432-3
更新日期：1985-03-01 00:00:00
abstract：OBJECTIVE:To investigate the expression and localization of interleukin-8 (IL-8) and monocyte chemotactic protein 1 (MCP-1) in women with and without endometriosis. DESIGN:Comparative immunohistochemical study. SETTING:Academic medical center. PATIENT(S):Ectopic (n = 24) and homologous eutopic endometrium (n = 24) f...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.12.067
更新日期：2009-03-01 00:00:00
abstract：:Anaphylactic reaction associated with hysteroscopy using 32% dextran-70 as a distending medium is a rare phenomenon. We report anaphylactic reaction associated with hysteroscopy using dextran that was delivered manually in three otherwise healthy women occurring within a 6-month period. The rapidity and pressure of de...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)54317-9
更新日期：1991-05-01 00:00:00
abstract：OBJECTIVE:To introduce a combined laparovaginal metroplasty approach to the treatment of bicornuate uterus. DESIGN:Case report. SETTING:Private community hospital. PATIENT:A nulliparous patient with three recurrent spontaneous midtrimester abortions and a double uterus on hysterosalpingogram was evaluated laparoscop...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)58235-1
更新日期：1996-04-01 00:00:00
abstract：OBJECTIVE:To improve the maturation rate of murine and human germinal vesicle (GV) oocytes using human tubal epithelial cells (hTECs). DESIGN:Murine and human GV oocytes were randomized to human tubal fluid (HTF) media alone or cocultured with mouse embryonic fibroblasts (MEFs) or primary hTECs or immortalized hTECS (...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2010.08.034
更新日期：2011-03-15 00:00:00
abstract：OBJECTIVE:To compare sperm morphology of electrostimulated ejaculates of spinal cord-injured (SCI) men with that of manual ejaculates of an able-bodied population. DESIGN:Retrospective study. PATIENTS:Spinal cord-injured men (n = 21) participating in a reproductive rehabilitation program and able-bodied men (n = 163)...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)57561-x
更新日期：1995-05-01 00:00:00
abstract：:To assess whether procedures of semen preparation can reduce the proportion of antibody-coated spermatozoa, semen samples with positive direct mixed antiglobulin reaction (MAR) were washed in media supplemented with 10% or 50% fetal cord serum (FCS). Washing reduced the MAR to a negative level, but the MAR was identic...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)53169-0
更新日期：1989-12-01 00:00:00
abstract：OBJECTIVE:To perform a systematic review and meta-analysis of studies that compared the prevalence of anxiety symptoms in women with polycystic ovary syndrome (PCOS) and control women. DESIGN:Meta-analysis and systematic review. SETTING:University practice. PATIENT(S):Cross-sectional studies comparing PCOS subjects ...
journal_title：Fertility and sterility
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.fertnstert.2011.10.022
更新日期：2012-01-01 00:00:00
abstract：OBJECTIVE:To study the correlation between genital phenotype and cystic fibrosis genotype in men lacking at least one vas deferens. DESIGN:Prospective study. SETTING:Institut Rhônalpin pour la Reproduction Humaine, Lyon-Bron, France. PATIENT(S):Forty-seven infertile men lacking at least one vas deferens. INTERVENTI...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(02)02954-0
更新日期：2002-05-01 00:00:00
abstract：:Hormonal profiles were compared in 14 ovulatory women who were treated with two different doses of gonadotropins in successive in vitro fertilization cycles. All patients suffered from mechanical causes of infertility. Serum estradiol (E2), follicle-stimulating hormone (FSH), luteinizing hormone (LH), and progesterone...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1988-06-01 00:00:00
abstract：:The use of cryopreserved semen offers the possibility of home insemination by the instructed partner. A comparative study was designed whereby participants were randomly allocated to use home or clinic insemination for six cycles. If no pregnancy had occurred after six cycles, the site of insemination was switched to ...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0015-0282(16)59956-7
更新日期：1988-06-01 00:00:00
abstract：:The addition of 4% dl-methionine to a diet of 18% or 12% casein reduced pregnancy maintenance in the rat from 100% to 48% and 5%, respectively. Fetal weight was subnormal. The major influence of methionine was not due to reduced food intake as determined by pair-fed controls but was related to reduced ovarian function...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)42563-x
更新日期：1977-05-01 00:00:00
abstract：:One hundred and twenty rats were divided into six groups and laparotomized. In three of the groups the cecum was left intact. In one of these groups the cecum was only lifted up through the abdominal incision and then replaced in the abdominal cavity. In another group the intact cecum was bathed with a certain amount ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)43584-3
更新日期：1978-10-01 00:00:00
abstract：OBJECTIVE:To determine whether there is an association between abnormal semen parameters and occupational exposures to organic solvents, metals, and pesticides. DESIGN:Case-control study using three case groups based on different cutoff values for semen parameters and one standard reference group. SETTING:University ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(98)00542-1
更新日期：1999-04-01 00:00:00
